Transient neonatal zinc deficiency due to a new autosomal dominant mutation in gene SLC30A2 (ZnT-2)

Pediatric Dermatology

Volumn 31, Issue 2, 2014, Pages 251-252

  Lova Navarro, Miguel ^a   Vera Casaño, Ángel ^a   Benito Lõpez, Carmen ^b   Fernández Ballesteros, María D ^a   Godoy Díaz, Daniel J ^a   Crespo Erchiga, Antonio ^a   Romero Brufau, Santiago ^c  

^a HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^b HOSPITAL MATERNO INFANTIL   (Spain)

^c MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; STEROID; ZINC; CATION TRANSPORT PROTEIN; SLC30A2 PROTEIN, HUMAN;

ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CASE REPORT; FEMALE; GENE; GENE MUTATION; HUMAN; INFANT; NEWBORN DISEASE; PRIORITY JOURNAL; SKIN DEFECT; SLC30A2 GENE; TRANSIENT NEONATAL ZINC DEFICIENCY; ZINC BLOOD LEVEL; ZINC DEFICIENCY; BREAST MILK; CHEMISTRY; GENETICS; METAL METABOLISM, INBORN ERRORS; MUTATION;

CATION TRANSPORT PROTEINS; FEMALE; HUMANS; INFANT; METAL METABOLISM, INBORN ERRORS; MILK, HUMAN; MUTATION; ZINC;

EID: 84895920452     PISSN: 07368046     EISSN: 15251470     Source Type: Journal    
DOI: 10.1111/pde.12257     Document Type: Article

References (5)

1. Kumar P, Lal NR, Mondal AK, et al. Zinc and skin: a brief summary. Dermatol Online J 2012; 18: 1.
2. Murthy SC, Udagani MM, Badakali AV, et al. Symptomatic zinc deficiency in a full-term breast-fed infant. Dermatol Online J 2010; 16: 3.
3. Chowanadisai W, Lönnerdal B, Kelleher SL,. Identification of a mutation in SLC30A2 (ZnT-2) in women with low milk zinc concentration that results in transient neonatal zinc deficiency. J Biol Chem 2006; 281: 39699-39707.
4. Lasry I, Seo YA, Ityel H, et al. A dominant negative heterozygous G87R mutation in the zinc transporter, ZnT-2 (SLC30A2), results in transient neonatal zinc deficiency. J Biol Chem 2012; 287: 29348-29361.
5. Glover MT, Atherton DJ,. Transient zinc deficiency in two full-term breast-fed siblings associated with low maternal breast milk zinc concentration. Pediatr Dermatol 1988; 5: 10-13.