-
1
-
-
71449099347
-
The balance of autocrine vegf-A and vegf-c determines podocyte survival
-
Muller-Deile J, Worthmann K, Saleem M et al. The balance of autocrine VEGF-A and VEGF-C determines podocyte survival. Am J Physiol Renal Physiol 2009; 297: F1656-F1667
-
(2009)
Am J Physiol Renal Physiol
, vol.297
-
-
Muller-Deile, J.1
Worthmann, K.2
Saleem, M.3
-
2
-
-
33746610964
-
Autocrine vegf-A system in podocytes regulates podocin and its interaction with cd2ap
-
Guan F, Villegas G, Teichman J et al. Autocrine VEGF-A system in podocytes regulates podocin and its interaction with CD2AP. Am J Physiol Renal Physiol 2006; 291: F422-F428
-
(2006)
Am J Physiol Renal Physiol
, vol.291
-
-
Guan, F.1
Villegas, G.2
Teichman, J.3
-
3
-
-
70349782389
-
An overview of small-molecule inhibitors of vegfr signaling
-
Ivy SP, Wick JY, Kaufman BM. An overview of small-molecule inhibitors of VEGFR signaling. Nat Rev Clin Oncol 2009; 6: 569-579
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 569-579
-
-
Ivy, S.P.1
Wick, J.Y.2
Kaufman, B.M.3
-
4
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel RS. Tumor angiogenesis. N Engl J Med 2008; 358: 2039-2049
-
(2008)
N Engl J Med
, vol.358
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
5
-
-
33144483703
-
Vascular endothelial growth factor localization in the adult
-
Maharaj AS, Saint-Geniez M, Maldonado AE et al. Vascular endothelial growth factor localization in the adult. Am J Pathol 2006; 168: 639-648
-
(2006)
Am J Pathol
, vol.168
, pp. 639-648
-
-
Maharaj, A.S.1
Saint-Geniez, M.2
Maldonado, A.E.3
-
6
-
-
0032907687
-
Vascular endothelial growth factor (VEGF) and its receptors
-
Neufeld G, Cohen T, Gengrinovitch S et al. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 1999; 13: 9-22
-
(1999)
FASEB J
, vol.13
, pp. 9-22
-
-
Neufeld, G.1
Cohen, T.2
Gengrinovitch, S.3
-
7
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki D, Itin A, Soffer D et al. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992; 359: 843-845
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
-
8
-
-
0242670019
-
Pdgfra activating mutations in gastrointestinal stromal tumors
-
Heinrich MC, Corless CL, Duensing A et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science 2003; 299: 708-710
-
(2003)
Science
, vol.299
, pp. 708-710
-
-
Heinrich, M.C.1
Corless, C.L.2
Duensing, A.3
-
9
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350: 2335-2342
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
11
-
-
34447329590
-
Spectrum of activity and mechanism of action of vegf/pdgf inhibitors
-
Homsi J, Daud AI. Spectrum of activity and mechanism of action of VEGF/PDGF inhibitors. Cancer Control 2007; 14: 285-294
-
(2007)
Cancer Control
, vol.14
, pp. 285-294
-
-
Homsi, J.1
Daud, A.I.2
-
12
-
-
40849130173
-
Vegf inhibition and renal thrombotic microangiopathy
-
Eremina V, Jefferson JA, Kowalewska J et al. VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med 2008; 358: 1129-1136
-
(2008)
N Engl J Med
, vol.358
, pp. 1129-1136
-
-
Eremina, V.1
Jefferson, J.A.2
Kowalewska, J.3
-
13
-
-
35948974274
-
Minimal change nephropathy and focal segmental glomerulosclerosis
-
Mathieson PW. Minimal change nephropathy and focal segmental glomerulosclerosis. Semin Immunopathol 2007; 29: 415-426
-
(2007)
Semin Immunopathol
, vol.29
, pp. 415-426
-
-
Mathieson, P.W.1
-
15
-
-
44349176408
-
RelA Ser276 phosphorylation is required for activation of a subset of NF-kappaB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes
-
Nowak DE, Tian B, Jamaluddin M et al. RelA Ser276 phosphorylation is required for activation of a subset of NF-kappaB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes. Mol Cell Biol 2008; 28: 3623-3638
-
(2008)
Mol Cell Biol
, vol.28
, pp. 3623-3638
-
-
Nowak, D.E.1
Tian, B.2
Jamaluddin, M.3
-
16
-
-
0032039076
-
Phosphorylation of nf-kappa b p65 by pka stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator cbp/p300
-
Zhong H, Voll RE, Ghosh S. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol Cell 1998; 1: 661-671
-
(1998)
Mol Cell
, vol.1
, pp. 661-671
-
-
Zhong, H.1
Voll, R.E.2
Ghosh, S.3
-
17
-
-
70349675898
-
Nuclear nf-kappab p65 phosphorylation at serine 276 by protein kinase a contributes to the malignant phenotype of head and neck cancer
-
Arun P, Brown MS, Ehsanian R et al. Nuclear NF-kappaB p65 phosphorylation at serine 276 by protein kinase A contributes to the malignant phenotype of head and neck cancer. Clin Cancer Res 2009; 15: 5974-5984
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5974-5984
-
-
Arun, P.1
Brown, M.S.2
Ehsanian, R.3
-
18
-
-
72449132908
-
Vegf signalling inhibition-induced proteinuria: Mechanisms, significance and management
-
Izzedine H, Massard C, Spano JP et al. VEGF signalling inhibition-induced proteinuria: Mechanisms, significance and management. Eur J Cancer 2010; 46: 439-448
-
(2010)
Eur J Cancer
, vol.46
, pp. 439-448
-
-
Izzedine, H.1
Massard, C.2
Spano, J.P.3
-
19
-
-
34247597779
-
Proteinuria in a patient receiving anti-vegf therapy for metastatic renal cell carcinoma
-
Roncone D, Satoskar A, Nadasdy T et al. Proteinuria in a patient receiving anti-VEGF therapy for metastatic renal cell carcinoma. Nat Clin Pract Nephrol 2007; 3: 287-293
-
(2007)
Nat Clin Pract Nephrol
, vol.3
, pp. 287-293
-
-
Roncone, D.1
Satoskar, A.2
Nadasdy, T.3
-
20
-
-
33846484966
-
Renal thrombotic microangiopathy caused by anti-VEGF-Antibody treatment for metastatic renal-cell carcinoma
-
Frangie C, Lefaucheur C, Medioni J et al. Renal thrombotic microangiopathy caused by anti-VEGF-Antibody treatment for metastatic renal-cell carcinoma. Lancet Oncol 2007; 8: 177-178
-
(2007)
Lancet Oncol
, vol.8
, pp. 177-178
-
-
Frangie, C.1
Lefaucheur, C.2
Medioni, J.3
-
22
-
-
58449096748
-
Thrombotic microangiopathy secondary to VEGF pathway inhibition by sunitinib
-
Bollee G, Patey N, Cazajous G et al. Thrombotic microangiopathy secondary to VEGF pathway inhibition by sunitinib. Nephrol Dial Transplant 2009; 24: 682-685
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 682-685
-
-
Bollee, G.1
Patey, N.2
Cazajous, G.3
-
23
-
-
34548305272
-
Vascular endothelial cellspecific NF-kappaB suppression attenuates hypertension-induced renal damage
-
Henke N, Schmidt-Ullrich R, Dechend R et al. Vascular endothelial cellspecific NF-kappaB suppression attenuates hypertension-induced renal damage. Circ Res 2007; 101: 268-276
-
(2007)
Circ Res
, vol.101
, pp. 268-276
-
-
Henke, N.1
Schmidt-Ullrich, R.2
Dechend, R.3
-
24
-
-
34548295887
-
Endothelial nf-kappab as a mediator of kidney damage: The missing link between systemic vascular and renal disease
-
Guzik TJ, Harrison DG. Endothelial NF-kappaB as a mediator of kidney damage: The missing link between systemic vascular and renal disease? Circ Res 2007; 101: 227-229
-
(2007)
Circ Res
, vol.101
, pp. 227-229
-
-
Guzik, T.J.1
Harrison, D.G.2
-
25
-
-
26944437123
-
Nf-kappab-dependent increase in intrarenal angiotensin ii induced by proteinuria
-
Takase O, Marumo T, Imai N et al. NF-kappaB-dependent increase in intrarenal angiotensin II induced by proteinuria. Kidney Int 2005; 68: 464-473
-
(2005)
Kidney Int
, vol.68
, pp. 464-473
-
-
Takase, O.1
Marumo, T.2
Imai, N.3
-
26
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
Yang JC, Haworth L, Sherry RM et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003; 349: 427-434
-
(2003)
N Engl J Med
, vol.349
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
-
27
-
-
0033538057
-
The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling
-
Thakker GD, Hajjar DP, Muller WA et al. The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling. J Biol Chem 1999; 274: 10002-10007
-
(1999)
J Biol Chem
, vol.274
, pp. 10002-10007
-
-
Thakker, G.D.1
Hajjar, D.P.2
Muller, W.A.3
-
28
-
-
33845953426
-
Phosphorylation of tyr1214 within vegfr-2 triggers the recruitment of nck and activation of fyn leading to sapk2/p38 activation and endothelial cell migration in response to vegf
-
Lamalice L, Houle F, Huot J. Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF. J Biol Chem 2006; 281: 34009-34020
-
(2006)
J Biol Chem
, vol.281
, pp. 34009-34020
-
-
Lamalice, L.1
Houle, F.2
Huot, J.3
-
29
-
-
20044394412
-
Vegf treatment induces signaling pathways that regulate both actin polymerization and depolymerization
-
Gong C, Stoletov KV, Terman BI. VEGF treatment induces signaling pathways that regulate both actin polymerization and depolymerization. Angiogenesis 2004; 7: 313-321
-
(2004)
Angiogenesis
, vol.7
, pp. 313-321
-
-
Gong, C.1
Stoletov, K.V.2
Terman, B.I.3
-
30
-
-
77955870854
-
Overexpression of vegf-A in podocytes of adult mice causes glomerular disease
-
Veron D, Reidy KJ, Bertuccio C et al. Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease. Kidney Int 2010; 77: 989-999
-
(2010)
Kidney Int
, vol.77
, pp. 989-999
-
-
Veron, D.1
Reidy, K.J.2
Bertuccio, C.3
-
31
-
-
81155123707
-
Vascular endothelial growth factor receptor 2 direct interaction with nephrin links vegf-A signals to actin in kidney podocytes
-
Bertuccio C, Veron D, Aggarwal PK et al. Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes. J Biol Chem 2011; 286: 39933-39944
-
(2011)
J Biol Chem
, vol.286
, pp. 39933-39944
-
-
Bertuccio, C.1
Veron, D.2
Aggarwal, P.K.3
-
32
-
-
77957861954
-
Glomerular structure and function require paracrine, not autocrine, vegf-vegfr-2 signaling
-
Sison K, Eremina V, Baelde H et al. Glomerular structure and function require paracrine, not autocrine, VEGF-VEGFR-2 signaling. J Am Soc Nephrol 2010; 21: 1691-1701
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1691-1701
-
-
Sison, K.1
Eremina, V.2
Baelde, H.3
-
33
-
-
84867519785
-
Soluble flt1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function
-
Jin J, Sison K, Li C et al. Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function. Cell 2012; 151: 384-399
-
(2012)
Cell
, vol.151
, pp. 384-399
-
-
Jin, J.1
Sison, K.2
Li, C.3
-
34
-
-
67849096609
-
Sorafenib inhibits nuclear factor kappa b, decreases inducible nitric oxide synthase and cyclooxygenase-2 expression, and restores working memory in appswe mice
-
Echeverria V, Burgess S, Gamble-George J et al. Sorafenib inhibits nuclear factor kappa B, decreases inducible nitric oxide synthase and cyclooxygenase-2 expression, and restores working memory in APPswe mice. Neuroscience 2009; 162: 1220-1231
-
(2009)
Neuroscience
, vol.162
, pp. 1220-1231
-
-
Echeverria, V.1
Burgess, S.2
Gamble-George, J.3
-
35
-
-
77953835378
-
C-mip impairs podocyte proximal signaling and induces heavy proteinuria
-
Zhang SY, Kamal M, Dahan K et al. c-mip impairs podocyte proximal signaling and induces heavy proteinuria. Sci Signal 2010; 3: Ra39
-
(2010)
Sci Signal
, vol.3
-
-
Zhang, S.Y.1
Kamal, M.2
Dahan, K.3
-
36
-
-
84874658636
-
Upregulation of c-mip is closely related to podocyte dysfunction in membranous nephropathy
-
Sendeyo K, Audard V, Zhang SY et al. Upregulation of c-mip is closely related to podocyte dysfunction in membranous nephropathy. Kidney Int 2013; 83: 414-425
-
(2013)
Kidney Int
, vol.83
, pp. 414-425
-
-
Sendeyo, K.1
Audard, V.2
Zhang, S.Y.3
-
37
-
-
33745812440
-
Genetic and functional analyses of membrane cofactor protein (cd46) mutations in atypical hemolytic uremic syndrome
-
Fremeaux-Bacchi V, Moulton EA, Kavanagh D et al. Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome. J Am Soc Nephrol 2006; 17: 2017-2025
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2017-2025
-
-
Fremeaux-Bacchi, V.1
Moulton, E.A.2
Kavanagh, D.3
-
38
-
-
0035885927
-
Specific von willebrand factor-cleaving protease in thrombotic microangiopathies: A study of 111 cases
-
Veyradier A, Obert B, Houllier A et al. Specific von Willebrand factor-cleaving protease in thrombotic microangiopathies: A study of 111 cases. Blood 2001; 98: 1765-1772
-
(2001)
Blood
, vol.98
, pp. 1765-1772
-
-
Veyradier, A.1
Obert, B.2
Houllier, A.3
-
39
-
-
0034796901
-
Lf15-0195 prevents the induction and inhibits the progression of rat anti-gbm disease
-
Tesch GH, Hill PA, Wei M et al. LF15-0195 prevents the induction and inhibits the progression of rat anti-GBM disease. Kidney Int 2001; 60: 1354-1365
-
(2001)
Kidney Int
, vol.60
, pp. 1354-1365
-
-
Tesch, G.H.1
Hill, P.A.2
Wei, M.3
-
40
-
-
35848934112
-
Quantification of renal pathology by image analysis
-
Rangan GK, Tesch GH. Quantification of renal pathology by image analysis. Nephrology (Carlton) 2007; 12: 553-558
-
(2007)
Nephrology (Carlton
, vol.12
, pp. 553-558
-
-
Rangan, G.K.1
Tesch, G.H.2
-
41
-
-
0015620349
-
A technique for ultracryotomy of cell suspensions and tissues
-
Tokuyasu KT. A technique for ultracryotomy of cell suspensions and tissues. J Cell Biol 1973; 57: 551-565
-
(1973)
J Cell Biol
, vol.57
, pp. 551-565
-
-
Tokuyasu, K.T.1
-
42
-
-
0031563832
-
Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines
-
Mundel P, Reiser J, Zuniga Mejia Borja A et al. Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines. Exp Cell Res 1997; 236: 248-258
-
(1997)
Exp Cell Res
, vol.236
, pp. 248-258
-
-
Mundel, P.1
Reiser, J.2
Zuniga Mejia Borja, A.3
-
43
-
-
0029059060
-
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
-
Beg AA, Sha WC, Bronson RT et al. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature 1995; 376: 167-170
-
(1995)
Nature
, vol.376
, pp. 167-170
-
-
Beg, A.A.1
Sha, W.C.2
Bronson, R.T.3
-
44
-
-
0026489365
-
The high mobility group protein hmg i(y) is required for nf-kappa b-dependent virus induction of the human ifnbeta gene
-
Thanos D, Maniatis T. The high mobility group protein HMG I(Y) is required for NF-kappa B-dependent virus induction of the human IFNbeta gene. Cell 1992; 71: 777-789
-
(1992)
Cell
, vol.71
, pp. 777-789
-
-
Thanos, D.1
Maniatis, T.2
-
45
-
-
59249088848
-
C-mip interacts physically with RelA and inhibits nuclear factor kappa B activity
-
Kamal M, Valanciute A, Dahan K et al. C-mip interacts physically with RelA and inhibits nuclear factor kappa B activity. Mol Immunol 2009; 46: 991-998
-
(2009)
Mol Immunol
, vol.46
, pp. 991-998
-
-
Kamal, M.1
Valanciute, A.2
Dahan, K.3
-
46
-
-
0036024957
-
Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation
-
Wells J, Farnham PJ. Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation. Methods 2002; 26: 48-56
-
(2002)
Methods
, vol.26
, pp. 48-56
-
-
Wells, J.1
Farnham, P.J.2
-
47
-
-
0034911645
-
Transcriptional and posttranscriptional alterations of IkappaBalpha in active minimal-change nephrotic syndrome
-
Sahali D, Pawlak A, Le Gouvello S et al. Transcriptional and posttranscriptional alterations of IkappaBalpha in active minimal-change nephrotic syndrome. J Am Soc Nephrol 2001; 12: 1648-1658
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 1648-1658
-
-
Sahali, D.1
Pawlak, A.2
Le Gouvello, S.3
-
48
-
-
0024404496
-
Uv-induced dna damage is an intermediate step in uv-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein
-
Stein B, Rahmsdorf HJ, Steffen A et al. UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein. Mol Cell Biol 1989; 9: 5169-5181
-
(1989)
Mol Cell Biol
, vol.9
, pp. 5169-5181
-
-
Stein, B.1
Rahmsdorf, H.J.2
Steffen, A.3
|