메뉴 건너뛰기




Volumn 264, Issue , 2014, Pages 99-111

Epigenetic regulation in neurodevelopment and neurodegenerative diseases

Author keywords

Alzheimer's disease; Epigenetics; Huntington's disease; Imprinting disorders; Neurodevelopment; Parkinson's disease

Indexed keywords

DNA METHYLTRANSFERASE; GLIAL FIBRILLARY ACIDIC PROTEIN; METHYL CPG BINDING PROTEIN 2; PROTEIN S100B;

EID: 84895897607     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.11.040     Document Type: Review
Times cited : (78)

References (179)
  • 1
    • 84859107964 scopus 로고    scopus 로고
    • Cellular models to investigate biochemical pathways in Parkinson's disease
    • Alberio T., Lopiano L., Fasano M. Cellular models to investigate biochemical pathways in Parkinson's disease. FEBS J 2012, 279:1146-1155.
    • (2012) FEBS J , vol.279 , pp. 1146-1155
    • Alberio, T.1    Lopiano, L.2    Fasano, M.3
  • 2
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir R.E., Van den Veyver I.B., Wan M., Tran C.Q., Francke U., Zoghbi H.Y. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 1999, 23:185-188.
    • (1999) Nat Genet , vol.23 , pp. 185-188
    • Amir, R.E.1    Van den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 4
    • 34548202642 scopus 로고    scopus 로고
    • Nap1l2 promotes histone acetylation activity during neuronal differentiation
    • Attia M., Rachez C., De Pauw A., Avner P., Rogner U.C. Nap1l2 promotes histone acetylation activity during neuronal differentiation. Mol Cell Biol 2007, 27:6093-6102.
    • (2007) Mol Cell Biol , vol.27 , pp. 6093-6102
    • Attia, M.1    Rachez, C.2    De Pauw, A.3    Avner, P.4    Rogner, U.C.5
  • 5
    • 11844279705 scopus 로고    scopus 로고
    • DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2
    • Bai S., Ghoshal K., Datta J., Majumder S., Yoon S.O., Jacob S.T. DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2. Mol Cell Biol 2005, 25:751-766.
    • (2005) Mol Cell Biol , vol.25 , pp. 751-766
    • Bai, S.1    Ghoshal, K.2    Datta, J.3    Majumder, S.4    Yoon, S.O.5    Jacob, S.T.6
  • 6
    • 19344378337 scopus 로고    scopus 로고
    • REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
    • Ballas N., Grunseich C., Lu D.D., Speh J.C., Mandel G. REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 2005, 121:645-657.
    • (2005) Cell , vol.121 , pp. 645-657
    • Ballas, N.1    Grunseich, C.2    Lu, D.D.3    Speh, J.C.4    Mandel, G.5
  • 7
    • 60749102039 scopus 로고    scopus 로고
    • Non-cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology
    • Ballas N., Lioy D.T., Grunseich C., Mandel G. Non-cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology. Nat Neurosci 2009, 12:311-317.
    • (2009) Nat Neurosci , vol.12 , pp. 311-317
    • Ballas, N.1    Lioy, D.T.2    Grunseich, C.3    Mandel, G.4
  • 8
    • 25844443895 scopus 로고    scopus 로고
    • History of genetic disease: the molecular genetics of Huntington disease - a history
    • Bates G.P. History of genetic disease: the molecular genetics of Huntington disease - a history. Nat Rev Genet 2005, 6:766-773.
    • (2005) Nat Rev Genet , vol.6 , pp. 766-773
    • Bates, G.P.1
  • 9
    • 67249150482 scopus 로고    scopus 로고
    • Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus
    • Ben-Shachar S., Chahrour M., Thaller C., Shaw C.A., Zoghbi H.Y. Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus. Hum Mol Genet 2009, 18:2431-2442.
    • (2009) Hum Mol Genet , vol.18 , pp. 2431-2442
    • Ben-Shachar, S.1    Chahrour, M.2    Thaller, C.3    Shaw, C.A.4    Zoghbi, H.Y.5
  • 10
    • 84860229552 scopus 로고    scopus 로고
    • The epigenetic effects of butyrate: potential therapeutic implications for clinical practice
    • Berni Canani R., Di Costanzo M., Leone L. The epigenetic effects of butyrate: potential therapeutic implications for clinical practice. Clin Epigenetics 2012, 4:4.
    • (2012) Clin Epigenetics , vol.4 , pp. 4
    • Berni Canani, R.1    Di Costanzo, M.2    Leone, L.3
  • 11
    • 77957927865 scopus 로고    scopus 로고
    • The genetics of Alzheimer disease: back to the future
    • Bertram L., Lill C.M., Tanzi R.E. The genetics of Alzheimer disease: back to the future. Neuron 2010, 68:270-281.
    • (2010) Neuron , vol.68 , pp. 270-281
    • Bertram, L.1    Lill, C.M.2    Tanzi, R.E.3
  • 12
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002, 16:6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 13
    • 84866723225 scopus 로고    scopus 로고
    • A critical and cell-autonomous role for MeCP2 in synaptic scaling up
    • Blackman M.P., Djukic B., Nelson S.B., Turrigiano G.G. A critical and cell-autonomous role for MeCP2 in synaptic scaling up. J Neurosci 2012, 32:13529-13536.
    • (2012) J Neurosci , vol.32 , pp. 13529-13536
    • Blackman, M.P.1    Djukic, B.2    Nelson, S.B.3    Turrigiano, G.G.4
  • 14
    • 0038206578 scopus 로고    scopus 로고
    • Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment
    • Blalock E.M., Chen K.-C., Sharrow K., Herman J.P., Porter N., Foster T., Landfield P. Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment. J Neurosci 2003, 23:3807-3819.
    • (2003) J Neurosci , vol.23 , pp. 3807-3819
    • Blalock, E.M.1    Chen, K.-C.2    Sharrow, K.3    Herman, J.P.4    Porter, N.5    Foster, T.6    Landfield, P.7
  • 15
    • 84869089691 scopus 로고    scopus 로고
    • Epigenetic inheritance of disease and disease risk
    • Bohacek J., Mansuy I.M. Epigenetic inheritance of disease and disease risk. Neuropsychopharmacology 2013, 38:220-236.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 220-236
    • Bohacek, J.1    Mansuy, I.M.2
  • 18
    • 83855163995 scopus 로고    scopus 로고
    • Uncovering the role of 5-hydroxymethylcytosine in the epigenome
    • Branco M.R., Ficz G., Reik W. Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat Rev Genet 2012, 13:7-13.
    • (2012) Nat Rev Genet , vol.13 , pp. 7-13
    • Branco, M.R.1    Ficz, G.2    Reik, W.3
  • 21
    • 0030006003 scopus 로고    scopus 로고
    • DNA mismatch repair and DNA methylation in adult brain neurons
    • Brooks P.J., Marietta C., Goldman D. DNA mismatch repair and DNA methylation in adult brain neurons. J Neurosci 1996, 16:939-945.
    • (1996) J Neurosci , vol.16 , pp. 939-945
    • Brooks, P.J.1    Marietta, C.2    Goldman, D.3
  • 22
    • 56349116391 scopus 로고    scopus 로고
    • Molecular genetics of Alzheimer's disease: an update
    • Brouwers N., Sleegers K., Van Broeckhoven C. Molecular genetics of Alzheimer's disease: an update. Ann Med 2008, 40:562-583.
    • (2008) Ann Med , vol.40 , pp. 562-583
    • Brouwers, N.1    Sleegers, K.2    Van Broeckhoven, C.3
  • 25
    • 61849157257 scopus 로고    scopus 로고
    • Alzheimer's disease
    • Burns A., Iliffe S. Alzheimer's disease. BMJ 2009, 338:b158.
    • (2009) BMJ , vol.338
    • Burns, A.1    Iliffe, S.2
  • 26
    • 0035816661 scopus 로고    scopus 로고
    • A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
    • Cao X., Sudhof T.C. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 2001, 293:115-120.
    • (2001) Science , vol.293 , pp. 115-120
    • Cao, X.1    Sudhof, T.C.2
  • 27
    • 0033651946 scopus 로고    scopus 로고
    • Prader-Willi and Angelman syndromes: sister imprinted disorders
    • Cassidy S.B., Dykens E., Williams C.A. Prader-Willi and Angelman syndromes: sister imprinted disorders. Am J Med Genet 2000, 97:136-146.
    • (2000) Am J Med Genet , vol.97 , pp. 136-146
    • Cassidy, S.B.1    Dykens, E.2    Williams, C.A.3
  • 28
    • 84863281305 scopus 로고    scopus 로고
    • Age-related memory impairment is associated with disrupted multivariate epigenetic coordination in the hippocampus
    • Castellano J.F., Fletcher B.R., Kelley-Bell B., Kim D.H., Gallagher M., Rapp P.R. Age-related memory impairment is associated with disrupted multivariate epigenetic coordination in the hippocampus. PLoS One 2012, 7:e33249.
    • (2012) PLoS One , vol.7
    • Castellano, J.F.1    Fletcher, B.R.2    Kelley-Bell, B.3    Kim, D.H.4    Gallagher, M.5    Rapp, P.R.6
  • 29
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • Chahrour M., Jung S.Y., Shaw C., Zhou X., Wong S.T., Qin J., Zoghbi H.Y. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 2008, 320:1224-1229.
    • (2008) Science , vol.320 , pp. 1224-1229
    • Chahrour, M.1    Jung, S.Y.2    Shaw, C.3    Zhou, X.4    Wong, S.T.5    Qin, J.6    Zoghbi, H.Y.7
  • 30
    • 35648978121 scopus 로고    scopus 로고
    • The story of Rett syndrome: from clinic to neurobiology
    • Chahrour M., Zoghbi H.Y. The story of Rett syndrome: from clinic to neurobiology. Neuron 2007, 56:422-437.
    • (2007) Neuron , vol.56 , pp. 422-437
    • Chahrour, M.1    Zoghbi, H.Y.2
  • 31
    • 77955406842 scopus 로고    scopus 로고
    • Angelman syndrome, a genomic imprinting disorder of the brain
    • Chamberlain S.J., Lalande M. Angelman syndrome, a genomic imprinting disorder of the brain. J Neurosci 2010, 30:9958-9963.
    • (2010) J Neurosci , vol.30 , pp. 9958-9963
    • Chamberlain, S.J.1    Lalande, M.2
  • 32
    • 77952885487 scopus 로고    scopus 로고
    • Neurodevelopmental disorders involving genomic imprinting at human chromosome 15q11-q13
    • Chamberlain S.J., Lalande M. Neurodevelopmental disorders involving genomic imprinting at human chromosome 15q11-q13. Neurobiol Dis 2010, 39:13-20.
    • (2010) Neurobiol Dis , vol.39 , pp. 13-20
    • Chamberlain, S.J.1    Lalande, M.2
  • 33
    • 0035093830 scopus 로고    scopus 로고
    • Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
    • Chen R.Z., Akbarian S., Tudor M., Jaenisch R. Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat Genet 2001, 27:327-331.
    • (2001) Nat Genet , vol.27 , pp. 327-331
    • Chen, R.Z.1    Akbarian, S.2    Tudor, M.3    Jaenisch, R.4
  • 37
    • 84862317109 scopus 로고    scopus 로고
    • Genetics and epigenetics of Parkinson's disease
    • Coppede F. Genetics and epigenetics of Parkinson's disease. ScientificWorldJournal 2012, 2012:489830.
    • (2012) ScientificWorldJournal , vol.2012 , pp. 489830
    • Coppede, F.1
  • 38
    • 77953892400 scopus 로고    scopus 로고
    • Molecular mechanisms of neurodegeneration in Alzheimer's disease
    • Crews L., Masliah E. Molecular mechanisms of neurodegeneration in Alzheimer's disease. Hum Mol Genet 2010, 19:R12-R20.
    • (2010) Hum Mol Genet , vol.19
    • Crews, L.1    Masliah, E.2
  • 41
    • 84895860417 scopus 로고    scopus 로고
    • Genome-wide exploration of DNA methylation in the aging brain and its relation to Alzheimer's disease
    • (April (Meeting Abstracts 1)): P05070.
    • De Jager P, Srivatsava G, Eaton M, Chibnik L, Kellis M, Bennett D (2012) Genome-wide exploration of DNA methylation in the aging brain and its relation to Alzheimer's disease. Neurology 78(April (Meeting Abstracts 1)): P05070.
    • (2012) Neurology , vol.78
    • De Jager, P.1    Srivatsava, G.2    Eaton, M.3    Chibnik, L.4    Kellis, M.5    Bennett, D.6
  • 43
    • 77957243426 scopus 로고    scopus 로고
    • Parkinson's disease: is there a strong environmental contribution?
    • Elbaz A., Moisan F. Parkinson's disease: is there a strong environmental contribution?. Rev Neurol (Paris) 2010, 166:757-763.
    • (2010) Rev Neurol (Paris) , vol.166 , pp. 757-763
    • Elbaz, A.1    Moisan, F.2
  • 44
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 2007, 8:286-298.
    • (2007) Nat Rev Genet , vol.8 , pp. 286-298
    • Esteller, M.1
  • 45
    • 77954034515 scopus 로고    scopus 로고
    • Additive effects of physical exercise and environmental enrichment on adult hippocampal neurogenesis in mice
    • Fabel K., Wolf S.A., Ehninger D., Babu H., Leal-Galicia P., Kempermann G. Additive effects of physical exercise and environmental enrichment on adult hippocampal neurogenesis in mice. Front Neurosci 2009, 3:50.
    • (2009) Front Neurosci , vol.3 , pp. 50
    • Fabel, K.1    Wolf, S.A.2    Ehninger, D.3    Babu, H.4    Leal-Galicia, P.5    Kempermann, G.6
  • 48
    • 78049427089 scopus 로고    scopus 로고
    • Introduction to epigenomics and epigenome-wide analysis
    • Fazzari M.J., Greally J.M. Introduction to epigenomics and epigenome-wide analysis. Methods Mol Biol 2010, 620:243-265.
    • (2010) Methods Mol Biol , vol.620 , pp. 243-265
    • Fazzari, M.J.1    Greally, J.M.2
  • 49
    • 76549135113 scopus 로고    scopus 로고
    • Evolution in health and medicine Sackler colloquium: stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease
    • Feinberg A.P., Irizarry R.A. Evolution in health and medicine Sackler colloquium: stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease. Proc Natl Acad Sci U S A 2010, 107:1757-1764.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 1757-1764
    • Feinberg, A.P.1    Irizarry, R.A.2
  • 50
    • 16444381345 scopus 로고    scopus 로고
    • Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
    • Feng J., Chang H., Li E., Fan G. Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J Neurosci Res 2005, 79:734-746.
    • (2005) J Neurosci Res , vol.79 , pp. 734-746
    • Feng, J.1    Chang, H.2    Li, E.3    Fan, G.4
  • 51
    • 34247469843 scopus 로고    scopus 로고
    • Epigenetic regulation of neural gene expression and neuronal function
    • Feng J., Fouse S., Fan G. Epigenetic regulation of neural gene expression and neuronal function. Pediatr Res 2007, 61:58R-63R.
    • (2007) Pediatr Res , vol.61
    • Feng, J.1    Fouse, S.2    Fan, G.3
  • 52
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • Feng J., Zhou Y., Campbell S.L., Le T., Li E., Sweatt J.D., Silva A.J., Fan G. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci 2010, 13:423-430.
    • (2010) Nat Neurosci , vol.13 , pp. 423-430
    • Feng, J.1    Zhou, Y.2    Campbell, S.L.3    Le, T.4    Li, E.5    Sweatt, J.D.6    Silva, A.J.7    Fan, G.8
  • 55
    • 34248523169 scopus 로고    scopus 로고
    • Recovery of learning and memory is associated with chromatin remodelling
    • Fischer A., Sananbenesi F., Wang X., Dobbin M., Tsai L.H. Recovery of learning and memory is associated with chromatin remodelling. Nature 2007, 447:178-182.
    • (2007) Nature , vol.447 , pp. 178-182
    • Fischer, A.1    Sananbenesi, F.2    Wang, X.3    Dobbin, M.4    Tsai, L.H.5
  • 58
    • 0037423186 scopus 로고    scopus 로고
    • The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation
    • Fuks F., Hurd P.J., Wolf D., Nan X., Bird A.P., Kouzarides T. The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation. J Biol Chem 2003, 278:4035-4040.
    • (2003) J Biol Chem , vol.278 , pp. 4035-4040
    • Fuks, F.1    Hurd, P.J.2    Wolf, D.3    Nan, X.4    Bird, A.P.5    Kouzarides, T.6
  • 59
    • 79960007644 scopus 로고    scopus 로고
    • The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells
    • Gao Z., Ure K., Ding P., Nashaat M., Yuan L., Ma J., Hammer R.E., Hsieh J. The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells. J Neurosci 2011, 31:9772-9786.
    • (2011) J Neurosci , vol.31 , pp. 9772-9786
    • Gao, Z.1    Ure, K.2    Ding, P.3    Nashaat, M.4    Yuan, L.5    Ma, J.6    Hammer, R.E.7    Hsieh, J.8
  • 61
    • 84864003941 scopus 로고    scopus 로고
    • Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation
    • Gonzales M.L., Adams S., Dunaway K.W., LaSalle J.M. Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation. Mol Cell Biol 2012, 32:2894-2903.
    • (2012) Mol Cell Biol , vol.32 , pp. 2894-2903
    • Gonzales, M.L.1    Adams, S.2    Dunaway, K.W.3    LaSalle, J.M.4
  • 62
    • 0028267714 scopus 로고
    • Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice
    • Goto K., Numata M., Komura J.I., Ono T., Bestor T.H., Kondo H. Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation 1994, 56:39-44.
    • (1994) Differentiation , vol.56 , pp. 39-44
    • Goto, K.1    Numata, M.2    Komura, J.I.3    Ono, T.4    Bestor, T.H.5    Kondo, H.6
  • 63
    • 44649134044 scopus 로고    scopus 로고
    • Epigenetic codes in cognition and behaviour
    • Gräff J., Mansuy I.M. Epigenetic codes in cognition and behaviour. Behav Brain Res 2008, 192:70-87.
    • (2008) Behav Brain Res , vol.192 , pp. 70-87
    • Gräff, J.1    Mansuy, I.M.2
  • 64
    • 84876679234 scopus 로고    scopus 로고
    • Dynamic histone marks in the hippocampus and cortex facilitate memory consolidation
    • Gräff J., Woldemichael B.T., Berchtold D., Dewarrat G., Mansuy I.M. Dynamic histone marks in the hippocampus and cortex facilitate memory consolidation. Nat Commun 2012, 3:991.
    • (2012) Nat Commun , vol.3 , pp. 991
    • Gräff, J.1    Woldemichael, B.T.2    Berchtold, D.3    Dewarrat, G.4    Mansuy, I.M.5
  • 65
    • 37249010514 scopus 로고    scopus 로고
    • Structural basis for the recognition and cross-linking of amyloid fibrils by human apolipoprotein E
    • Gunzburg M.J., Perugini M.A., Howlett G.J. Structural basis for the recognition and cross-linking of amyloid fibrils by human apolipoprotein E. J Biol Chem 2007, 282:35831-35841.
    • (2007) J Biol Chem , vol.282 , pp. 35831-35841
    • Gunzburg, M.J.1    Perugini, M.A.2    Howlett, G.J.3
  • 66
    • 33847266846 scopus 로고    scopus 로고
    • Reversal of neurological defects in a mouse model of Rett syndrome
    • Guy J., Gan J., Selfridge J., Cobb S., Bird A. Reversal of neurological defects in a mouse model of Rett syndrome. Science 2007, 315:1143-1147.
    • (2007) Science , vol.315 , pp. 1143-1147
    • Guy, J.1    Gan, J.2    Selfridge, J.3    Cobb, S.4    Bird, A.5
  • 67
    • 0035094767 scopus 로고    scopus 로고
    • A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
    • Guy J., Hendrich B., Holmes M., Martin J.E., Bird A. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 2001, 27:322-326.
    • (2001) Nat Genet , vol.27 , pp. 322-326
    • Guy, J.1    Hendrich, B.2    Holmes, M.3    Martin, J.E.4    Bird, A.5
  • 69
    • 84856147847 scopus 로고    scopus 로고
    • Epigenetics in nucleotide repeat expansion disorders
    • He F., Todd P.K. Epigenetics in nucleotide repeat expansion disorders. Semin Neurol 2011, 31:470-483.
    • (2011) Semin Neurol , vol.31 , pp. 470-483
    • He, F.1    Todd, P.K.2
  • 70
    • 42649140229 scopus 로고    scopus 로고
    • Events at the transition between cell cycle exit and oligodendrocyte progenitor differentiation: the role of HDAC and YY1
    • He Y., Sandoval J., Casaccia-Bonnefil P. Events at the transition between cell cycle exit and oligodendrocyte progenitor differentiation: the role of HDAC and YY1. Neuron Glia Biol 2007, 3:221-231.
    • (2007) Neuron Glia Biol , vol.3 , pp. 221-231
    • He, Y.1    Sandoval, J.2    Casaccia-Bonnefil, P.3
  • 72
    • 77952678006 scopus 로고    scopus 로고
    • Epigenetic control of neural precursor cell fate during development
    • Hirabayashi Y., Gotoh Y. Epigenetic control of neural precursor cell fate during development. Nat Rev Neurosci 2010, 11:377-388.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 377-388
    • Hirabayashi, Y.1    Gotoh, Y.2
  • 74
    • 9344252804 scopus 로고    scopus 로고
    • Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells
    • Hsieh J., Nakashima K., Kuwabara T., Mejia E., Gage F.H. Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc Natl Acad Sci U S A 2004, 101:16659-16664.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 16659-16664
    • Hsieh, J.1    Nakashima, K.2    Kuwabara, T.3    Mejia, E.4    Gage, F.H.5
  • 75
    • 67650711853 scopus 로고    scopus 로고
    • DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation
    • Hutnick L.K., Golshani P., Namihira M., Xue Z., Matynia A., Yang X.W., Silva A.J., Schweizer F.E., Fan G. DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Hum Mol Genet 2009, 18:2875-2888.
    • (2009) Hum Mol Genet , vol.18 , pp. 2875-2888
    • Hutnick, L.K.1    Golshani, P.2    Namihira, M.3    Xue, Z.4    Matynia, A.5    Yang, X.W.6    Silva, A.J.7    Schweizer, F.E.8    Fan, G.9
  • 77
    • 0035839057 scopus 로고    scopus 로고
    • The role of DNA methylation in mammalian epigenetics
    • Jones P.A., Takai D. The role of DNA methylation in mammalian epigenetics. Science 2001, 293:1068-1070.
    • (2001) Science , vol.293 , pp. 1068-1070
    • Jones, P.A.1    Takai, D.2
  • 78
    • 77951842993 scopus 로고    scopus 로고
    • Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains
    • Jowaed A., Schmitt I., Kaut O., Wullner U. Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains. J Neurosci 2010, 30:6355-6359.
    • (2010) J Neurosci , vol.30 , pp. 6355-6359
    • Jowaed, A.1    Schmitt, I.2    Kaut, O.3    Wullner, U.4
  • 79
    • 79957533104 scopus 로고    scopus 로고
    • Non-coding RNAs as regulators of gene expression and epigenetics
    • Kaikkonen M.U., Lam M.T., Glass C.K. Non-coding RNAs as regulators of gene expression and epigenetics. Cardiovasc Res 2011, 90:430-440.
    • (2011) Cardiovasc Res , vol.90 , pp. 430-440
    • Kaikkonen, M.U.1    Lam, M.T.2    Glass, C.K.3
  • 82
    • 43049168861 scopus 로고    scopus 로고
    • Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation
    • Kim M.O., Chawla P., Overland R.P., Xia E., Sadri-Vakili G., Cha J.H. Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation. J Neurosci 2008, 28:3947-3957.
    • (2008) J Neurosci , vol.28 , pp. 3947-3957
    • Kim, M.O.1    Chawla, P.2    Overland, R.P.3    Xia, E.4    Sadri-Vakili, G.5    Cha, J.H.6
  • 83
    • 79955060261 scopus 로고    scopus 로고
    • Regulation of expression and activity of DNA (cytosine-5) methyltransferases in mammalian cells
    • Kinney S.R., Pradhan S. Regulation of expression and activity of DNA (cytosine-5) methyltransferases in mammalian cells. Prog Mol Biol Transl Sci 2011, 101:311-333.
    • (2011) Prog Mol Biol Transl Sci , vol.101 , pp. 311-333
    • Kinney, S.R.1    Pradhan, S.2
  • 84
    • 8744229966 scopus 로고    scopus 로고
    • MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex
    • Klose R.J., Bird A.P. MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex. J Biol Chem 2004, 279:46490-46496.
    • (2004) J Biol Chem , vol.279 , pp. 46490-46496
    • Klose, R.J.1    Bird, A.P.2
  • 85
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: the mark and its mediators
    • Klose R.J., Bird A.P. Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 2006, 31:89-97.
    • (2006) Trends Biochem Sci , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 86
    • 33749583553 scopus 로고    scopus 로고
    • Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity
    • Kontopoulos E., Parvin J.D., Feany M.B. Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity. Hum Mol Genet 2006, 15:3012-3023.
    • (2006) Hum Mol Genet , vol.15 , pp. 3012-3023
    • Kontopoulos, E.1    Parvin, J.D.2    Feany, M.B.3
  • 88
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 2007, 128:693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 89
    • 70350432817 scopus 로고    scopus 로고
    • The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases
    • Lahiri D.K., Maloney B., Zawia N.H. The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases. Mol Psychiatry 2009, 14:992-1003.
    • (2009) Mol Psychiatry , vol.14 , pp. 992-1003
    • Lahiri, D.K.1    Maloney, B.2    Zawia, N.H.3
  • 90
    • 1942520420 scopus 로고    scopus 로고
    • Challenges in Parkinson's disease: restoration of the nigrostriatal dopamine system is not enough
    • Lang A.E., Obeso J.A. Challenges in Parkinson's disease: restoration of the nigrostriatal dopamine system is not enough. Lancet Neurol 2004, 3:309-316.
    • (2004) Lancet Neurol , vol.3 , pp. 309-316
    • Lang, A.E.1    Obeso, J.A.2
  • 91
    • 34748863568 scopus 로고    scopus 로고
    • High histone acetylation and decreased polycomb repressive complex 2 member levels regulate gene specific transcriptional changes during early embryonic stem cell differentiation induced by retinoic acid
    • Lee E.R., Murdoch F.E., Fritsch M.K. High histone acetylation and decreased polycomb repressive complex 2 member levels regulate gene specific transcriptional changes during early embryonic stem cell differentiation induced by retinoic acid. Stem Cells 2007, 25:2191-2199.
    • (2007) Stem Cells , vol.25 , pp. 2191-2199
    • Lee, E.R.1    Murdoch, F.E.2    Fritsch, M.K.3
  • 93
    • 79251647135 scopus 로고    scopus 로고
    • Neuronal chromatin dynamics of imprinting in development and disease
    • Leung K.N., Chamberlain S.J., Lalande M., LaSalle J.M. Neuronal chromatin dynamics of imprinting in development and disease. J Cell Biochem 2011, 112:365-373.
    • (2011) J Cell Biochem , vol.112 , pp. 365-373
    • Leung, K.N.1    Chamberlain, S.J.2    Lalande, M.3    LaSalle, J.M.4
  • 94
    • 84867633471 scopus 로고    scopus 로고
    • Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice
    • Li W., Calfa G., Larimore J., Pozzo-Miller L. Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice. Proc Natl Acad Sci U S A 2012, 109:17087-17092.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 17087-17092
    • Li, W.1    Calfa, G.2    Larimore, J.3    Pozzo-Miller, L.4
  • 97
    • 77956099873 scopus 로고    scopus 로고
    • Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation
    • Liu C., Teng Z.Q., Santistevan N.J., Szulwach K.E., Guo W., Jin P., Zhao X. Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation. Cell Stem Cell 2010, 6:433-444.
    • (2010) Cell Stem Cell , vol.6 , pp. 433-444
    • Liu, C.1    Teng, Z.Q.2    Santistevan, N.J.3    Szulwach, K.E.4    Guo, W.5    Jin, P.6    Zhao, X.7
  • 98
    • 3042631024 scopus 로고    scopus 로고
    • Gene regulation and DNA damage in the ageing human brain
    • Lu T., et al. Gene regulation and DNA damage in the ageing human brain. Nature 2004, 429:883-891.
    • (2004) Nature , vol.429 , pp. 883-891
    • Lu, T.1
  • 101
    • 35448949103 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells
    • Lyssiotis C.A., Walker J., Wu C., Kondo T., Schultz P.G., Wu X. Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells. Proc Natl Acad Sci U S A 2007, 104:14982-14987.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 14982-14987
    • Lyssiotis, C.A.1    Walker, J.2    Wu, C.3    Kondo, T.4    Schultz, P.G.5    Wu, X.6
  • 103
    • 65549144456 scopus 로고    scopus 로고
    • Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions
    • Maezawa I., Swanberg S., Harvey D., LaSalle J.M., Jin L.W. Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions. J Neurosci 2009, 29:5051-5061.
    • (2009) J Neurosci , vol.29 , pp. 5051-5061
    • Maezawa, I.1    Swanberg, S.2    Harvey, D.3    LaSalle, J.M.4    Jin, L.W.5
  • 104
    • 0141429160 scopus 로고    scopus 로고
    • A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations
    • Marambaud P., Wen P.H., Dutt A., Shioi J., Takashima A., Siman R., Robakis N.K. A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations. Cell 2003, 114:635-645.
    • (2003) Cell , vol.114 , pp. 635-645
    • Marambaud, P.1    Wen, P.H.2    Dutt, A.3    Shioi, J.4    Takashima, A.5    Siman, R.6    Robakis, N.K.7
  • 105
    • 0036897351 scopus 로고    scopus 로고
    • Histone deacetylase activity is necessary for oligodendrocyte lineage progression
    • Marin-Husstege M., Muggironi M., Liu A., Casaccia-Bonnefil P. Histone deacetylase activity is necessary for oligodendrocyte lineage progression. J Neurosci 2002, 22:10333-10345.
    • (2002) J Neurosci , vol.22 , pp. 10333-10345
    • Marin-Husstege, M.1    Muggironi, M.2    Liu, A.3    Casaccia-Bonnefil, P.4
  • 106
    • 0242300612 scopus 로고    scopus 로고
    • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
    • Martinowich K., Hattori D., Wu H., Fouse S., He F., Hu Y., Fan G., Sun Y.E. DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 2003, 302:890-893.
    • (2003) Science , vol.302 , pp. 890-893
    • Martinowich, K.1    Hattori, D.2    Wu, H.3    Fouse, S.4    He, F.5    Hu, Y.6    Fan, G.7    Sun, Y.E.8
  • 110
    • 79956209852 scopus 로고    scopus 로고
    • Adult neurogenesis in the mammalian brain: significant answers and significant questions
    • Ming G.L., Song H. Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron 2011, 70:687-702.
    • (2011) Neuron , vol.70 , pp. 687-702
    • Ming, G.L.1    Song, H.2
  • 111
    • 0030582991 scopus 로고    scopus 로고
    • Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile Parkinsonism and Parkinson's disease
    • Mogi M., Harada M., Narabayashi H., Inagaki H., Minami M., Nagatsu T. Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile Parkinsonism and Parkinson's disease. Neurosci Lett 1996, 211:13-16.
    • (1996) Neurosci Lett , vol.211 , pp. 13-16
    • Mogi, M.1    Harada, M.2    Narabayashi, H.3    Inagaki, H.4    Minami, M.5    Nagatsu, T.6
  • 114
    • 4143141064 scopus 로고    scopus 로고
    • Developmental stage dependent regulation of DNA methylation and chromatin modification in a immature astrocyte specific gene promoter
    • Namihira M., Nakashima K., Taga T. Developmental stage dependent regulation of DNA methylation and chromatin modification in a immature astrocyte specific gene promoter. FEBS Lett 2004, 572:184-188.
    • (2004) FEBS Lett , vol.572 , pp. 184-188
    • Namihira, M.1    Nakashima, K.2    Taga, T.3
  • 115
    • 75649094081 scopus 로고    scopus 로고
    • Pharmacology of epigenetics in brain disorders
    • Narayan P., Dragunow M. Pharmacology of epigenetics in brain disorders. Br J Pharmacol 2010, 159:285-303.
    • (2010) Br J Pharmacol , vol.159 , pp. 285-303
    • Narayan, P.1    Dragunow, M.2
  • 117
    • 82955220477 scopus 로고    scopus 로고
    • Alzheimer's disease: pathological mechanisms and recent insights
    • Niedowicz D.M., Nelson P.T., Murphy M.P. Alzheimer's disease: pathological mechanisms and recent insights. Curr Neuropharmacol 2011, 9:674-684.
    • (2011) Curr Neuropharmacol , vol.9 , pp. 674-684
    • Niedowicz, D.M.1    Nelson, P.T.2    Murphy, M.P.3
  • 119
    • 33645451188 scopus 로고    scopus 로고
    • The role of DMDs in the maintenance of epigenetic states
    • Paoloni-Giacobino A., Chaillet J. The role of DMDs in the maintenance of epigenetic states. Cytogenet Genome Res 2006, 113:116-121.
    • (2006) Cytogenet Genome Res , vol.113 , pp. 116-121
    • Paoloni-Giacobino, A.1    Chaillet, J.2
  • 122
    • 56449115830 scopus 로고    scopus 로고
    • Different methylation of the TNF-alpha promoter in cortex and substantia nigra: implications for selective neuronal vulnerability
    • Pieper H.C., Evert B.O., Kaut O., Riederer P.F., Waha A., Wullner U. Different methylation of the TNF-alpha promoter in cortex and substantia nigra: implications for selective neuronal vulnerability. Neurobiol Dis 2008, 32:521-527.
    • (2008) Neurobiol Dis , vol.32 , pp. 521-527
    • Pieper, H.C.1    Evert, B.O.2    Kaut, O.3    Riederer, P.F.4    Waha, A.5    Wullner, U.6
  • 123
    • 41149142015 scopus 로고    scopus 로고
    • Epigenetics and complex disease: from etiology to new therapeutics
    • Ptak C., Petronis A. Epigenetics and complex disease: from etiology to new therapeutics. Annu Rev Pharmacol Toxicol 2008, 48:257-276.
    • (2008) Annu Rev Pharmacol Toxicol , vol.48 , pp. 257-276
    • Ptak, C.1    Petronis, A.2
  • 124
    • 0347624644 scopus 로고    scopus 로고
    • Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration
    • Rouaux C., Jokic N., Mbebi C., Boutillier S., Loeffler J.P., Boutillier A.L. Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration. EMBO J 2003, 22:6537-6549.
    • (2003) EMBO J , vol.22 , pp. 6537-6549
    • Rouaux, C.1    Jokic, N.2    Mbebi, C.3    Boutillier, S.4    Loeffler, J.P.5    Boutillier, A.L.6
  • 125
    • 33947534891 scopus 로고    scopus 로고
    • Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats
    • Rowe W.B., et al. Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats. J Neurosci 2007, 27:3098-3110.
    • (2007) J Neurosci , vol.27 , pp. 3098-3110
    • Rowe, W.B.1
  • 126
    • 33947534891 scopus 로고    scopus 로고
    • Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats
    • Rowe W.B., Blalock E.M., Chen K.C., Kadish I., Wang D., Barrett J.E., Thibault O., Porter N.M., Rose G.M., Landfield P.W. Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats. J Neurosci 2007, 27:3098-3110.
    • (2007) J Neurosci , vol.27 , pp. 3098-3110
    • Rowe, W.B.1    Blalock, E.M.2    Chen, K.C.3    Kadish, I.4    Wang, D.5    Barrett, J.E.6    Thibault, O.7    Porter, N.M.8    Rose, G.M.9    Landfield, P.W.10
  • 127
    • 73949103869 scopus 로고    scopus 로고
    • Epigenetic mediation of environmental influences in major psychotic disorders
    • Rutten B.P., Mill J. Epigenetic mediation of environmental influences in major psychotic disorders. Schizophr Bull 2009, 35:1045-1056.
    • (2009) Schizophr Bull , vol.35 , pp. 1045-1056
    • Rutten, B.P.1    Mill, J.2
  • 130
    • 84870016257 scopus 로고    scopus 로고
    • Female Mecp2+/- mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies
    • Samaco R.C., McGraw C.M., Ward C.S., Sun Y., Neul J.L., Zoghbi H.Y. Female Mecp2+/- mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies. Hum Mol Genet 2013, 22:96-109.
    • (2013) Hum Mol Genet , vol.22 , pp. 96-109
    • Samaco, R.C.1    McGraw, C.M.2    Ward, C.S.3    Sun, Y.4    Neul, J.L.5    Zoghbi, H.Y.6
  • 133
    • 52949153556 scopus 로고    scopus 로고
    • A mechanistic view of genomic imprinting
    • Sha K. A mechanistic view of genomic imprinting. Annu Rev Genomics Hum Genet 2008, 9:197-216.
    • (2008) Annu Rev Genomics Hum Genet , vol.9 , pp. 197-216
    • Sha, K.1
  • 134
    • 22344446199 scopus 로고    scopus 로고
    • Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain
    • Shen S., Li J., Casaccia-Bonnefil P. Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol 2005, 169:577-589.
    • (2005) J Cell Biol , vol.169 , pp. 577-589
    • Shen, S.1    Li, J.2    Casaccia-Bonnefil, P.3
  • 136
  • 142
    • 84857166398 scopus 로고    scopus 로고
    • Mutation of MeCP2 alters transcriptional regulation of select immediate-early genes
    • Su D., Cha Y.M., West A.E. Mutation of MeCP2 alters transcriptional regulation of select immediate-early genes. Epigenetics 2012, 7:146-154.
    • (2012) Epigenetics , vol.7 , pp. 146-154
    • Su, D.1    Cha, Y.M.2    West, A.E.3
  • 143
    • 1042289730 scopus 로고    scopus 로고
    • Decreased cAMP response element-mediated transcription: an early event in exon 1 and full-length cell models of Huntington's disease that contributes to polyglutamine pathogenesis
    • Sugars K.L., Brown R., Cook L.J., Swartz J., Rubinsztein D.C. Decreased cAMP response element-mediated transcription: an early event in exon 1 and full-length cell models of Huntington's disease that contributes to polyglutamine pathogenesis. J Biol Chem 2004, 279:4988-4999.
    • (2004) J Biol Chem , vol.279 , pp. 4988-4999
    • Sugars, K.L.1    Brown, R.2    Cook, L.J.3    Swartz, J.4    Rubinsztein, D.C.5
  • 144
    • 0035830503 scopus 로고    scopus 로고
    • Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms
    • Sun Y., Nadal-Vicens M., Misono S., Lin M.Z., Zubiaga A., Hua X., Fan G., Greenberg M.E. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 2001, 104:365-376.
    • (2001) Cell , vol.104 , pp. 365-376
    • Sun, Y.1    Nadal-Vicens, M.2    Misono, S.3    Lin, M.Z.4    Zubiaga, A.5    Hua, X.6    Fan, G.7    Greenberg, M.E.8
  • 147
    • 77949874234 scopus 로고    scopus 로고
    • Histone variants - ancient wrap artists of the epigenome
    • Talbert P.B., Henikoff S. Histone variants - ancient wrap artists of the epigenome. Nat Rev Mol Cell Biol 2010, 11:264-275.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 264-275
    • Talbert, P.B.1    Henikoff, S.2
  • 150
    • 61449339872 scopus 로고    scopus 로고
    • DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker
    • Tost J. DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker. Methods Mol Biol 2009, 507:3-20.
    • (2009) Methods Mol Biol , vol.507 , pp. 3-20
    • Tost, J.1
  • 152
    • 0037180492 scopus 로고    scopus 로고
    • Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain
    • Tudor M., Akbarian S., Chen R.Z., Jaenisch R. Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain. Proc Natl Acad Sci U S A 2002, 99:15536-15541.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 15536-15541
    • Tudor, M.1    Akbarian, S.2    Chen, R.Z.3    Jaenisch, R.4
  • 157
    • 70449725209 scopus 로고    scopus 로고
    • Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies
    • Urdinguio R.G., Sanchez-Mut J.V., Esteller M. Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. Lancet Neurol 2009, 8:1056-1072.
    • (2009) Lancet Neurol , vol.8 , pp. 1056-1072
    • Urdinguio, R.G.1    Sanchez-Mut, J.V.2    Esteller, M.3
  • 159
    • 25444533023 scopus 로고    scopus 로고
    • Exercise enhances learning and hippocampal neurogenesis in aged mice
    • van Praag H., Shubert T., Zhao C., Gage F.H. Exercise enhances learning and hippocampal neurogenesis in aged mice. J Neurosci 2005, 25:8680-8685.
    • (2005) J Neurosci , vol.25 , pp. 8680-8685
    • van Praag, H.1    Shubert, T.2    Zhao, C.3    Gage, F.H.4
  • 160
    • 78049294740 scopus 로고    scopus 로고
    • Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1
    • Villeneuve L.M., Kato M., Reddy M.A., Wang M., Lanting L., Natarajan R. Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1. Diabetes 2010, 59:2904-2915.
    • (2010) Diabetes , vol.59 , pp. 2904-2915
    • Villeneuve, L.M.1    Kato, M.2    Reddy, M.A.3    Wang, M.4    Lanting, L.5    Natarajan, R.6
  • 161
    • 79959730772 scopus 로고    scopus 로고
    • Epigenetics: deciphering its role in diabetes and its chronic complications
    • Villeneuve L.M., Reddy M.A., Natarajan R. Epigenetics: deciphering its role in diabetes and its chronic complications. Clin Exp Pharmacol Physiol 2011, 38:401-409.
    • (2011) Clin Exp Pharmacol Physiol , vol.38 , pp. 401-409
    • Villeneuve, L.M.1    Reddy, M.A.2    Natarajan, R.3
  • 163
    • 49949108971 scopus 로고    scopus 로고
    • Age-specific epigenetic drift in late-onset Alzheimer's disease
    • Wang S.C., Oelze B., Schumacher A. Age-specific epigenetic drift in late-onset Alzheimer's disease. PLoS One 2008, 3:e2698.
    • (2008) PLoS One , vol.3
    • Wang, S.C.1    Oelze, B.2    Schumacher, A.3
  • 164
    • 33749241112 scopus 로고    scopus 로고
    • Transition of mouse de novo methyltransferases expression from Dnmt3b to Dnmt3a during neural progenitor cell development
    • Watanabe D., Uchiyama K., Hanaoka K. Transition of mouse de novo methyltransferases expression from Dnmt3b to Dnmt3a during neural progenitor cell development. Neuroscience 2006, 142:727-737.
    • (2006) Neuroscience , vol.142 , pp. 727-737
    • Watanabe, D.1    Uchiyama, K.2    Hanaoka, K.3
  • 166
    • 79957567315 scopus 로고    scopus 로고
    • Physical exercise increases adult neurogenesis and telomerase activity, and improves behavioral deficits in a mouse model of schizophrenia
    • Wolf S.A., Melnik A., Kempermann G. Physical exercise increases adult neurogenesis and telomerase activity, and improves behavioral deficits in a mouse model of schizophrenia. Brain Behav Immun 2011, 25:971-980.
    • (2011) Brain Behav Immun , vol.25 , pp. 971-980
    • Wolf, S.A.1    Melnik, A.2    Kempermann, G.3
  • 167
    • 0033569641 scopus 로고    scopus 로고
    • Epigenetics: regulation through repression
    • Wolffe A.P., Matzke M.A. Epigenetics: regulation through repression. Science 1999, 286:481-486.
    • (1999) Science , vol.286 , pp. 481-486
    • Wolffe, A.P.1    Matzke, M.A.2
  • 168
    • 84876135874 scopus 로고    scopus 로고
    • Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome
    • Wood S.H., Craig T., Li Y., Merry B., de Magalhaes J.P. Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome. Age (Dordr) 2012, 4:4.
    • (2012) Age (Dordr) , vol.4 , pp. 4
    • Wood, S.H.1    Craig, T.2    Li, Y.3    Merry, B.4    de Magalhaes, J.P.5
  • 169
    • 77954842322 scopus 로고    scopus 로고
    • Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
    • Wu H., Coskun V., Tao J., Xie W., Ge W., Yoshikawa K., Li E., Zhang Y., Sun Y.E. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 2010, 329:444-448.
    • (2010) Science , vol.329 , pp. 444-448
    • Wu, H.1    Coskun, V.2    Tao, J.3    Xie, W.4    Ge, W.5    Yoshikawa, K.6    Li, E.7    Zhang, Y.8    Sun, Y.E.9
  • 170
    • 38149024924 scopus 로고    scopus 로고
    • Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD
    • Wu J., Basha M.R., Brock B., Cox D.P., Cardozo-Pelaez F., McPherson C.A., Harry J., Rice D.C., Maloney B., Chen D., Lahiri D.K., Zawia N.H. Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD. J Neurosci 2008, 28:3-9.
    • (2008) J Neurosci , vol.28 , pp. 3-9
    • Wu, J.1    Basha, M.R.2    Brock, B.3    Cox, D.P.4    Cardozo-Pelaez, F.5    McPherson, C.A.6    Harry, J.7    Rice, D.C.8    Maloney, B.9    Chen, D.10    Lahiri, D.K.11    Zawia, N.H.12
  • 173
    • 0035846826 scopus 로고    scopus 로고
    • Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide
    • Yasojima K., Akiyama H., McGeer E.G., McGeer P.L. Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide. Neurosci Lett 2001, 297:97-100.
    • (2001) Neurosci Lett , vol.297 , pp. 97-100
    • Yasojima, K.1    Akiyama, H.2    McGeer, E.G.3    McGeer, P.L.4
  • 175
    • 84865802076 scopus 로고    scopus 로고
    • Nutrition, adult hippocampal neurogenesis and mental health
    • Zainuddin M.S., Thuret S. Nutrition, adult hippocampal neurogenesis and mental health. Br Med Bull 2012, 103:89-114.
    • (2012) Br Med Bull , vol.103 , pp. 89-114
    • Zainuddin, M.S.1    Thuret, S.2
  • 176
    • 78650304236 scopus 로고    scopus 로고
    • Charting histone modifications and the functional organization of mammalian genomes
    • Zhou V.W., Goren A., Bernstein B.E. Charting histone modifications and the functional organization of mammalian genomes. Nat Rev Genet 2011, 12:7-18.
    • (2011) Nat Rev Genet , vol.12 , pp. 7-18
    • Zhou, V.W.1    Goren, A.2    Bernstein, B.E.3
  • 178
    • 34347364706 scopus 로고    scopus 로고
    • Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease
    • Zuccato C., Belyaev N., Conforti P., Ooi L., Tartari M., Papadimou E., MacDonald M., Fossale E., Zeitlin S., Buckley N., Cattaneo E. Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease. J Neurosci 2007, 27:6972-6983.
    • (2007) J Neurosci , vol.27 , pp. 6972-6983
    • Zuccato, C.1    Belyaev, N.2    Conforti, P.3    Ooi, L.4    Tartari, M.5    Papadimou, E.6    MacDonald, M.7    Fossale, E.8    Zeitlin, S.9    Buckley, N.10    Cattaneo, E.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.