Adrenomedullin and intermedin gene transcription is increased in leukocytes of patients with chronic heart failure at different stages of the disease

Peptides

Volumn 55, Issue , 2014, Pages 13-16

  Manuela, Cabiati ^a   Laura, Sabatino ^a   Benedetta, Svezia ^a   Raffaele, Caruso ^b   Alessandro, Verde ^c   Chiara, Caselli ^a   Tommaso, Prescimone ^a   Daniela, Giannessi ^a   Silvia, D R ^a  

^a INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^b CNR   (Italy)

^c OSPEDALE NIGUARDA CA GRANDA   (Italy)

Author keywords

Adrenomedullin; Heart failure; Human leukocytes; Intermedin; Leukocyte mRNA expression; Real Time PCR

Indexed keywords

ADRENOMEDULLIN; INTERMEDIN; MESSENGER RNA; ADM2 PROTEIN, HUMAN; PEPTIDE HORMONE;

ADULT; ARTICLE; BLOOD SAMPLING; CARDIAC PATIENT; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; FEMALE; GENE EXPRESSION PROFILING; GENE FUNCTION; HEART FAILURE; HUMAN; HUMAN CELL; LEUKOCYTE; MALE; MIDDLE AGED; NEW YORK HEART ASSOCIATION CLASS; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SEROLOGY TEST KIT; TRANSCRIPTOMICS; BLOOD; CHRONIC DISEASE; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PATHOLOGY;

ADRENOMEDULLIN; CHRONIC DISEASE; FEMALE; HEART FAILURE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; PEPTIDE HORMONES; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 84895835128     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2014.01.028     Document Type: Article

References (25)

1. D. Bell, and B.J. McDermott Intermedin (adrenomedullin-2): a novel counter-regulatory peptide in the cardiovascular and renal systems Br J Pharmacol 153 2008 S247 S262
2. M. Cabiati, L. Sabatino, R. Caruso, C. Caselli, T. Prescimone, and D. Giannessi et al. Gene expression of C-type natriuretic peptide and of its specific receptor NPR-B in human leukocytes of healthy and heart failure subjects Peptides 37 2012 240 246
3. M. Cabiati, R. Caruso, A. Verde, L. Sabatino, M.A. Morales, and S. Del Ry Transcriptomic profiling of the four adenosine receptors in human leukocytes of heart failure patients Biomed Res Int 2013 569438 10.1155/2013/569438
4. M. Cabiati, L. Sabatino, R. Caruso, A. Verde, C. Caselli, and T. Prescimone et al. C-type natriuretic peptide transcriptomic profiling increases in human leukocytes of patients with chronic heart failure as a function of clinical severity Peptides 47 2013 110 114
5. B. Cam-Etoz, N. Isbil-Buyukcoskun, and K. Ozluk Cardiovascular effects of the intracerebroventricular injection of adrenomedullin: roles of the peripheral vasopressin and central cholinergic systems Braz J Med Biol Res 45 2012 250 255
6. Y.S. Gong, X.F. Fan, X.M. Wu, L.G. Hu, C.S. Tang, and Y.Z. Pang et al. Changes of intermedin/adrenomedullin 2 and its receptors in the right ventricle of rats with chronic hypoxic pulmonary hypertension Sheng Li Xue Bao 59 2007 210 221
7. N. Hirayama, K. Kitamura, T. Imamura, J. Kato, Y. Koiwaya, and T. Tsuji et al. Molecular forms of circulating adrenomedullin in patients with congestive heart failure J Endocrinol 160 1999 297 303 (Pubitemid 29074701)
8. D. Holmes, M. Campbell, M. Harbinson, and D. Bell Protective effects of intermedin on cardiovascular, pulmonary and renal diseases: comparison with adrenomedullin and CGRP Curr Protein Pept Sci 14 2013 294 329
9. Y. Hong, D.L. Hay, R. Quirion, and D.R. Poyner The pharmacology of adrenomedullin 2/intermedin Br J Pharmacol 166 2012 110 120
10. N. Iqbal, K.S. Alim, H. Aramin, F. Iqbal, E. Green, and E. Higginbotham et al. Novel biomarkers for heart failure Expert Rev Cardiovasc Ther 11 2013 1155 1169
11. M. Jougasaki, R.J. Rodeheffer, M.M. Redfield, K. Yamamoto, C.M. Wei, and L.J. McKinley et al. Cardiac secretion of adrenomedullin in heart failure J Clin Invest 97 1996 2370 2376 (Pubitemid 26165726)
12. M. Jougasaki, and J.C. Burnett Jr. Adrenomedullin: potential in physiology and pathophysiology Life Sci 66 2000 855 872 (Pubitemid 30084473)
13. A. Kubo, N. Minamino, Y. Isumi, K. Kangawa, K. Dohi, and H. Matsuo Adrenomedullin production is correlated with differentiation in human leukemia cell lines and peripheral blood monocytes FEBS Lett 426 1998 233 237 (Pubitemid 28198133)
14. A. Kubo, N. Minamino, Y. Isumi, T. Katafuchi, K. Kangawa, and K. Dohi et al. Production of adrenomedullin in macrophage cell line and peritoneal macrophage J Biol Chem 273 1998 16730 16738 (Pubitemid 28311697)
15. M.A. Morales, S. Del Ry, U. Startari, M. Maltinti, C. Prontera, and M. Emdin et al. Plasma adrenomedullin relation with Doppler-derived dP/dt in patients with congestive heart failure Clin Cardiol 29 2006 126 130
16. M.G. Nicholls, C.J. Charles, J.G. Lainchbury, L.K. Lewis, M.T. Rademaker, and A.M. Richards et al. Adrenomedullin in heart failure Hypertens Res 26 2003 S135 S140
17. H. Nishida, T. Horio, Y. Suzuki, Y. Iwashima, K. Kamide, and K. Kangawa et al. Plasma adrenomedullin as an independent predictor of future cardiovascular events in high-risk patients: comparison with C-reactive protein and adiponectin Peptides 29 2008 599 605
18. F. Pousset, F. Masson, O. Chavirovskaia, R. Isnard, A. Carayon, and J.L. Golmard et al. Plasma adrenomedullin, a new independent predictor of prognosis in patients with chronic heart failure Eur Heart J 21 2000 1009 1014 (Pubitemid 30312090)
19. Y.W. Qin, X. Teng, J.Q. He, J. Du, C.S. Tang, and Y.F. Qi Increased plasma levels of intermedin and brain natriuretic peptide associated with severity of coronary stenosis in acute coronary syndrome Peptides 42 2013 84 88
20. J. Roh, C.L. Chang, A. Bhalla, C. Klein, and S.Y. Hsu Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes J Biol Chem 279 2004 7264 7274 (Pubitemid 38248876)
21. K. Swedberg, J. Cleland, H. Dargie, H. Drexler, F. Follath, and M. Komajda et al. Task Force for the Diagnosis, Treatment of Chronic Heart Failure of the European Society of Cardiology. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology Eur Heart J 26 2005 1115 1140
22. Y. Takei, K. Inoue, M. Ogoshi, T. Kawahara, H. Bannai, and S. Miyano Identification of novel adrenomedullin in mammals: a potent cardiovascular and renal regulator FEBS Lett 556 2004 53 58 (Pubitemid 38058554)
23. T. Tsuruda, and J.C. Burnett Jr. Adrenomedullin: an autocrine/paracrine factor for cardiorenal protection Circ Res 90 2002 625 627 (Pubitemid 34640877)
24. H.K. Wong, T.T. Cheung, and B.M. Cheung Adrenomedullin and cardiovascular diseases JRSM Cardiovasc Dis 2012 PII: cvd.2012.012003
25. H.Y. Zhang, W. Jiang, J.Y. Liu, Y. Li, C.L. Chen, and H.B. Xin et al. Intermedin is upregulated and has protective roles in a mouse ischemia/reperfusion model Hypertens Res 32 2009 861 868