The association between serum lipid levels, suicide ideation, and central serotonergic activity in patients with major depressive disorder

Journal of Affective Disorders

Volumn 159, Issue , 2014, Pages 62-65

  Park, Young Min ^a   Lee, Bun Hee ^a   Lee, Seung Hwan ^a  

^a Inje University College of Medicine   (South Korea)

Author keywords

Cholesterol; Depression; LDAEP; Lipid; Serotonin; Suicide ideation

Indexed keywords

BENZODIAZEPINE; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; TRIACYLGLYCEROL; ZOLPIDEM; LIPID;

ADULT; ARTICLE; BECK DEPRESSION INVENTORY; BODY MASS; CHOLESTEROL BLOOD LEVEL; CORRELATIONAL STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; EVOKED AUDITORY RESPONSE; FEMALE; HAMILTON SCALE; HUMAN; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; LOUDNESS DEPENDENCE OF AUDITORY EVOKED POTENTIAL; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MIDDLE AGED; MONOTHERAPY; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; SEROTONINERGIC SYSTEM; SUICIDAL IDEATION; TRIACYLGLYCEROL BLOOD LEVEL; AGED; BLOOD; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY;

ADULT; AGED; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER, MAJOR; EVOKED POTENTIALS, AUDITORY; FEMALE; HUMANS; LIPIDS; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; SEROTONIN; SUICIDAL IDEATION; TRIGLYCERIDES;

EID: 84895826254     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2014.01.016     Document Type: Article

References (31)

1. L.G. Almeida-Montes, V. Valles-Sanchez, J. Moreno-Aguilar, R.A. Chavez-Balderas, J.A. Garcia-Marin, J.F. Cortes Sotres, and G. Hheinze-Martin Relation of serum cholesterol, lipid, serotonin and tryptophan levels to severity of depression and to suicide attempts J. Psychiatry Neurosci. 25 2000 371 377
2. T.J. Chen, Y.W. Yu, M.C. Chen, S.Y. Wang, S.J. Tsai, and T.W. Lee Serotonin dysfunction and suicide attempts in major depressives: an auditory event-related potential study Neuropsychobiology 52 2005 28 36 (Pubitemid 40910947)
3. D. De Berardis, S. Marini, M. Piersanti, M. Cavuto, G. Perna, A. Valchera, M. Mazza, M. Fornaro, F. Iasevoli, G. Martinotti, and M. Di Giannantonio The relationships between cholesterol and suicide: an update ISRN Psychiatry 2012 2012 387901
4. E.A. Deisenhammer, K. Kramer-Reinstadler, D. Liensberger, G. Kemmler, H. Hinterhuber, and W.W. Fleischhacker No evidence for an association between serum cholesterol and the course of depression and suicidality Psychiatry Res. 121 2004 253 261 (Pubitemid 37522178)
5. H. Engelberg Low serum cholesterol and suicide Lancet 339 1992 727 729
6. P. Fischer, E. Gruenblatt, P. Pietschmann, and K.H. Tragl Serotonin transporter polymorphism and LDL-cholesterol Mol. Psychiatry 11 2006 707 709
7. U. Hegerl, and G. Juckel Intensity dependence of auditory evoked potentials as an indicator of central serotonergic neurotransmission: a new hypothesis Biol. Psychiatry 33 1993 173 187 (Pubitemid 23089966)
8. U. Hegerl, J. Gallinat, and G. Juckel Event-related potentials. Do they reflect central serotonergic neurotransmission and do they predict clinical response to serotonin agonists? J. Affect. Disord. 62 2001 93 100 (Pubitemid 32126614)
9. J.R. Hibbeln, and N. Salem Jr. Risks of cholesterol-lowering therapies Biol. Psychiatry 40 1996 686 687
10. G. Juckel, and U. Hegerl Evoked potentials, serotonin, and suicidality Pharmacopsychiatry 27 Suppl. 1 1994 S27 S29
11. G. Juckel, U. Hegerl, M. Molnar, V. Csepe, and G. Karmos Auditory evoked potentials reflect serotonergic neuronal activity - a study in behaving cats administered drugs acting on 5-HT1A autoreceptors in the dorsal raphe nucleus Neuropsychopharmacology 21 1999 710 716
12. D.H. Kim, and Y.M. Park The association between suicidality and serotonergic dysfunction in depressed patients J. Affect. Disord. 148 2013 72 76
13. H.J. Lee, and Y.K. Kim Serum lipid levels and suicide attempts Acta Psychiatr. Scand. 108 2003 215 221
14. K.S. Lee, Y.M. Park, and S.H. Lee Serotonergic dysfunction in patients with bipolar disorder assessed by the loudness dependence of the auditory evoked potential Psychiatry Investig. 9 2012 298 306
15. D. Lester The concentration of neurotransmitter metabolites in the cerebrospinal fluid of suicidal individuals: a meta-analysis Pharmacopsychiatry 28 1995 45 50
16. G. Lindberg, G. Larsson, S. Setterlind, and L. Rastam Serum lipids and mood in working men and women in Sweden J. Epidemiol. Community Health 48 1994 360 363 (Pubitemid 24271306)
17. M. Maes, J. Delanghe, H.Y. Meltzer, S. Scharpe, P. D×Hondt, and P. Cosyns Lower degree of esterification of serum cholesterol in depression: relevance for depression and suicide research Acta Psychiatr. Scand. 90 1994 252 258 (Pubitemid 24303592)
18. J.J. Mann, D. Currier, B. Stanley, M.A. Oquendo, L.V. Amsel, and S.P. Ellis Can biological tests assist prediction of suicide in mood disorders? Int. J. Neuropsychopharmacol. 9 2006 465 474 (Pubitemid 43979707)
19. L. McNally, Z. Bhagwagar, and J. Hannestad Inflammation, glutamate, and glia in depression: a literature review CNS Spectr 13 2008 501 510 (Pubitemid 351965454)
20. K. Paplos, B. Havaki-Kontaxaki, P. Ferentinos, M. Dasopoulou, and V. Kontaxakis Alexithymia, depression and serum lipids in suicide attempters Psychiatrike 23 2012 149 152
21. Y.M. Park Relationship between SSRI-induced sexual dysfunction and central serotonergic activity based on the loudness dependence of auditory evoked potentials Psychopharmacology (Berl.) 231 2014 551 555
22. Y.M. Park, and S.H. Lee Can the loudness dependence of auditory evoked potentials and suicidality be used to differentiate between depressive patients with and without bipolarity Psychiatry Investig. 10 2013 143 147
23. Y.M. Park, and S.H. Lee Clinical usefulness of loudness dependence of auditory evoked potentials (LDAEP) in patients with bipolar disorder Psychiatry Investig. 10 2013 233 237
24. Y.M. Park, S.H. Lee, S. Kim, and S.M. Bae The loudness dependence of the auditory evoked potential (LDAEP) in schizophrenia, bipolar disorder, major depressive disorder, anxiety disorder, and healthy controls Prog. Neuropsychopharmacol. Biol. Psychiatry 34 2010 313 316
25. Y.M. Park, D.W. Kim, S. Kim, C.H. Im, and S.H. Lee The loudness dependence of the auditory evoked potential (LDAEP) as a predictor of the response to escitalopram in patients with generalized anxiety disorder Psychopharmacology (Berl.) 213 2011 625 632
26. Y.M. Park, S.H. Lee, and E.J. Park Usefulness of LDAEP to predict tolerability to SSRIs in major depressive disorder: a case report Psychiatry Investig. 9 2012 80 82
27. J. Penttinen Hypothesis: low serum cholesterol, suicide, and interleukin-2 Am. J. Epidemiol. 141 1995 716 718
28. M. Pompili, G. Serafini, M. Innamorati, A.M. Moller-Leimkuhler, G. Giupponi, P. Girardi, R. Tatarelli, and D. Lester The hypothalamic-pituitary- adrenal axis and serotonin abnormalities: a selective overview for the implications of suicide prevention Eur. Arch. Psychiatry Clin. Neurosci. 260 2010 583 600
29. F. Pozzi, A. Troisi, M. Cerilli, A.M. Autore, C. Lo Castro, D. Ribatti, and G. Frajese Serum cholesterol and impulsivity in a large sample of healthy young men Psychiatry Res. 120 2003 239 245 (Pubitemid 38366051)
30. E. Repo-Tiihonen, P. Halonen, J. Tiihonen, and M. Virkkunen Total serum cholesterol level, violent criminal offences, suicidal behavior, mortality and the appearance of conduct disorder in Finnish male criminal offenders with antisocial personality disorder Eur. Arch. Psychiatry Clin. Neurosci. 252 2002 8 11 (Pubitemid 36056685)
31. J. Rybakowski, J. Ainiyet, Z. Szajnerman, and M. Zakrzewska The study of the relationship between cholesterol and lipid concentration and suicidal behavior in patients with schizophrenia affective illness Psychiatr. Pol. 30 1996 699 712 (Pubitemid 26392311)