BK virus disease after allogeneic stem cell transplantation: A cohort analysis

Biology of Blood and Marrow Transplantation

Volumn 20, Issue 4, 2014, Pages 564-570

  Rorije, Nienke M G ^a,b   Shea, Margaret M ^a   Satyanarayana, Gowri ^a   Hammond, Sarah P ^a,c   Ho, Vincent T ^c   Baden, Lindsey R ^a,c   Antin, Joseph H ^c   Soiffer, Robert J ^c   Marty, Francisco M ^a,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

Allogeneic stem cell transplantation; BK virus; Cord blood transplantation; Graft versus host disease; Human BK polyomavirus

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE; FLUDARABINE; GLUCOCORTICOID; METHOTREXATE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; TACROLIMUS;

ACUTE GRAFT VERSUS HOST DISEASE; ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; AGED; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ALLOGENEIC STEM CELL TRANSPLANTATION; ANEMIA; ARTICLE; BK VIRUS; BK VIRUS INFECTION; CHRONIC MYELOID LEUKEMIA; CHRONOTHERAPY; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG MEGADOSE; EPIDEMIOLOGY; FEMALE; GRAFT VERSUS HOST REACTION; HAZARD RATIO; HODGKIN DISEASE; HUMAN; IMMUNOPROPHYLAXIS; INCIDENCE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORBIDITY; MUCOSA INFLAMMATION; MULTIPLE MYELOMA; MYELOABLATIVE CONDITIONING; MYELODYSPLASTIC SYNDROME; MYELOPROLIFERATIVE DISORDER; NONHODGKIN LYMPHOMA; PLASMA CELL DYSCRASIA; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; RISK FACTOR; THROMBOTIC THROMBOCYTOPENIC PURPURA; UMBILICAL CORD BLOOD; URINALYSIS; URINARY TRACT DISEASE; URINE; VIRUS DETECTION; YOUNG ADULT;

ALLOGENEIC STEM CELL TRANSPLANTATION; BK VIRUS; CORD BLOOD TRANSPLANTATION; GRAFT-VERSUS-HOST DISEASE; HUMAN BK POLYOMAVIRUS;

ADULT; AGED; BK VIRUS; CHRONIC DISEASE; CORD BLOOD STEM CELL TRANSPLANTATION; CYCLOPHOSPHAMIDE; FEMALE; GRAFT VS HOST DISEASE; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MALE; MIDDLE AGED; MYCOPHENOLIC ACID; MYELOABLATIVE AGONISTS; POLYOMAVIRUS INFECTIONS; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS; TUMOR VIRUS INFECTIONS;

EID: 84895819022     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2014.01.014     Document Type: Article

References (46)

1. Copelan E.A. Hematopoietic stem-cell transplantation. NEngl J Med 2006, 354:1813-1826.
2. Pasquini M, Wang Z. Current use and outcome of hematopoietic stem cell transplantation. CIBMTR Summ. Slides 2011. Available at:. Accessed April 21,2012. http://www.cibmtr.org.
3. Gardner S., Field A., Coleman D., Hulme B. New papovavirus (B.K.) isolated from urine after renal transplantion. Lancet 1971, 1:253-257.
4. Chesters P.M., Heritage J., McCance D.J. Persistence of DNA sequences of BK virus and JC virus in normal persistence human tissues and in diseased tissues. JInfect Dis 1983, 147:676-684.
5. Reploeg M.D., Storch G.A., Clifford D.B. Bk virus: a clinical review. Clin Infect Dis 2001, 33:191-202.
6. Arthur R.R., Shah K.V., Baust S.J., Santos G.W., Saral R. Association of BK viruria with hemorrhagic cystitis in recipients of bone marrow transplants. NEngl J Med 1986, 315:230-234.
7. Bedi A., Miller C.B., Hanson J.L., et al. Association of BK virus with failure of prophylaxis against hemorrhagic cystitis following bone marrow transplantation. JClin Oncol 1995, 13:1103-1109.
8. Lekakis L.J., Macrinici V., Baraboutis I.G., et al. BK virus nephropathy after allogeneic stem cell transplantation: a case report and literature review. Am J Hematol 2009, 84:243-246.
9. Limaye A.P., Smith K.D., Cook L., et al. Polyomavirus nephropathy in native kidneys of non-renal transplant recipients. Am J Transplant 2005, 5:614-620.
10. Dalianis T., Ljungman P. Full myeloablative conditioning and an unrelated HLA mismatched donor increase the risk for BK virus-positive hemorrhagic cystitis in allogeneic hematopoetic stem cell transplanted patients. Anticancer Res 2011, 31:939-944.
11. Dropulic L.K., Jones R.J. Polyomavirus BK infection in blood and marrow transplant recipients. Bone Marrow Transplant 2008, 41:11-18.
12. Bennett S.M., Broekema N.M., Imperiale M.J. BK polyomavirus: Emerging pathogen. Microbes Infect 2012, 14:672-683.
13. Leung A.Y.H., Suen C., Lie A., et al. Quantification of polyoma BK viruria in hemorrhagic cystitis complicating bone marrow transplantation. Blood 2001, 98:1971-1978.
14. O'Donnell P.H., Swanson K., Josephson M.A., et al. BK virus infection is associated with hematuria and renal impairment in recipients of allogeneic hematopoietic stem cell transplants. Biol. Blood Marrow Transplant 2009, 15:1038-1048.
15. Apperley J.F., Rice S.J., Bishop J.A., et al. Late-onset hemorrhagic cystitis associated with urinary excretion of polyomaviruses after bone marrow transplantation. Transplantation 1987, 43:108-112.
16. Erard V., Storer B., Corey L., et al. BK virus infection in hematopoietic stem cell transplant recipients: frequency, risk factors, and association with postengraftment hemorrhagic cystitis. Clin Infect Dis 2004, 39:1861-1865.
17. Erard V., Kim H.W., Corey L., et al. BK DNA viral load in plasma: evidence for an association with hemorrhagic cystitis in allogeneic hematopoietic cell transplant recipients. Blood 2005, 106:1130-1132.
18. Sencer S.F., Haake R.J., Weisdorf D.J. Hemorrhagic cystitis after bone marrow transplantation. Transplantation 1993, 56:875-879.
19. Seber A., Shu X.O., Defor T., et al. Risk factors for severe hemorrhagic cystitis following BMT. Bone Marrow Transplant 1999, 23:35-40.
20. Leung A.Y.H., Mak R., Lie A.K.W., et al. Clinicopathological features and risk factors of clinically overt haemorrhagic cystitis complicating bone marrow transplantation. Bone Marrow Transplant 2002, 29:509-513.
21. Asano Y., Kanda Y., Ogawa N., et al. Male predominance among Japanese adult patients with late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation. Bone Marrow Transplant 2003, 32:1175-1179.
22. Tsuboi K., Kishi K., Ohmachi K., et al. Multivariate analysis of risk factors for hemorrhagic cystitis after hematopoietic stem cell transplantation. Bone Marrow Transplant 2003, 32:903-907.
23. Yamamoto R., Kusumi E., Kami M., et al. Late hemorrhagic cystitis after reduced-intensity hematopoietic stem cell transplantation (RIST). Bone Marrow Transplant 2003, 32:1089-1095.
24. El-Zimaity M., Saliba R., Chan K., et al. Hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation: donor type matters. Blood 2004, 103:4674-4680.
25. Giraud G., Bogdanovic G., Priftakis P., et al. The incidence of hemorrhagic cystitis and BK-viruria in allogeneic hematopoietic stem cell recipients according to intensity of the conditioning regimen. Haematologica 2006, 91:401-404.
26. Wong A.S.Y., Chan K.-H., Cheng V.C.C., et al. Relationship of pretransplantation polyoma BK virus serologic findings and BK viral reactivation after hematopoietic stem cell transplantation. Clin Infect Dis 2007, 44:830-837.
27. Giraud G., Priftakis P., Bogdanovic G., et al. BK-viruria and haemorrhagic cystitis are more frequent in allogeneic haematopoietic stem cell transplant patients receiving full conditioning and unrelated-HLA-mismatched grafts. Bone Marrow Transplant 2008, 41:737-742.
28. Tanaka K., Hori T., Hatakeyama N., et al. Quantification of BK polyoma viruria in Japanese children and adults with hemorrhagic cystitis complicating stem cell transplantation. JMed Virol 2008, 80:2108-2112.
29. De Padua Silva L., Patah P., Saliba R.M., et al. Hemorrhagic cystitis after allogeneic hematopoietic stem cell transplants is the complex result of BK virus infection, preparative regimen intensity and donor type. Haematologica 2010, 95:1183-1190.
30. Arai Y., Maeda T., Sugiura H., et al. Risk factors for and prognosis of hemorrhagic cystitis after allogeneic stem cell transplantation: Retrospective analysis in a single institution. Hematology 2012, 17:207-214.
31. Mori Y., Miyamoto T., Kato K., et al. Different risk factors related to adenovirus- or BK virus-associated hemorrhagic cystitis following allogeneic stem cell transplantation. Biol Blood Marrow Transplant 2012, 18:458-465.
32. Alyea E.P., Kim H.T., Ho V., et al. Comparative outcome of nonmyeloablative and myeloablative allogeneic hematopoietic cell transplantation for patients older than 50 years of age. Blood 2005, 105:1810-1814.
33. Mohty M., Gaugler B. Advances in umbilical cord transplantation: the role of thymoglobulin/ATG in cord blood transplantation. Best Pract Res Clin Haematol 2010, 23:275-282.
34. Cutler C., Stevenson K., Kim H.T., et al. Double umbilical cord blood transplantation with reduced intensity conditioning and sirolimus-based GVHD prophylaxis. Bone Marrow Transplant 2011, 46:659-667.
35. Shepherd B.J.D., Pringle L.E., Barnett M.J., et al. Mesna versus hyperhydration for the prevention of cyclophosphamide-induced hemorrhagic cystitis in bone marrow transplantation. JClin Oncol 1991, 9:2016-2020.
36. Ho V.T., Aldridge J., Kim H.T., et al. Comparison of tacrolimus and sirolimus (Tac/Sir) versus tacrolimus, sirolimus, and mini-methotrexate (Tac/Sir/MTX) as acute graft-versus-host disease prophylaxis after reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation. Biol Blood Marrow Transplant 2009, 15:844-850.
37. Cutler C., Li S., Ho V.T., et al. Extended follow-up of methotrexate-free immunosuppression using sirolimus and tacrolimus in related and unrelated donor peripheral blood stem cell transplantation. Blood 2007, 109:3108-3114.
38. Marty F.M., Bryar J., Browne S.K., et al. Sirolimus-based graft-versus-host disease prophylaxis protects against cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation: a cohort analysis. Blood 2007, 110:2-4.
39. Przepiorka D., Weisdorf D., Martin P., et al. 1994 Consensus Conference on Acute GVHD Grading. Bone Marrow Transplant 1995, 15:825-828.
40. Hill J.A., Koo S., Guzman Suarez B.B., et al. Cord-blood hematopoietic stem cell transplant confers an increased risk for human herpesvirus-6-associated acute limbic encephalitis: a cohort analysis. Biol. Blood Marrow Transplant 2012, 18:1638-1648.
41. Schulze M., Beck R., Igney A., et al. Computed tomography findings of human polyomavirus BK (BKV)-associated cystitis in allogeneic hematopoietic stem cell transplant recipients. Acta Radiol 2008, 49:1187-1194.
42. Leung A.Y.H., Chan M.T.L., Yuen K., et al. Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation. Clin Infect Dis 2005, 40:528-537.
43. Miller A.N., Glode A., Hogan K.R., et al. Efficacy and safety of ciprofloxacin for prophylaxis of polyomavirus BK virus-associated hemorrhagic cystitis in allogeneic hematopoietic stem cell transplantation recipients. Biol Blood Marrow Transplant 2011, 17:1176-1181.
44. Marty F.M., Lee S.J., Fahey M.M., et al. Infliximab use in patients with severe graft-versus-host disease and other emerging risk factors of non-Candida invasive fungal infections in allogeneic hematopoietic stem cell transplant recipients: a cohort study. Blood 2003, 102:2768-2776.
45. Leung A.Y.H., Yuen K.-Y., Kwong Y.-L. Polyoma BK virus and haemorrhagic cystitis in haematopoietic stem cell transplantation: a changing paradigm. Bone Marrow Transplant 2005, 36:929-937.
46. Syrjala K.L., Langer S.L., Abrams J.R., et al. Late effects of hematopoietic cell transplantation among 10-year adult survivors compared with case-matched controls. JClin Oncol 2005, 23:6596-6606.