The measurement of anti-müllerian hormone: A critical appraisal

Journal of Clinical Endocrinology and Metabolism

Volumn 99, Issue 3, 2014, Pages 723-732

  Rustamov, Oybek ^a   Smith, Alexander ^a   Roberts, Stephen A ^b   Yates, Allen P ^a   Fitzgerald, Cheryl ^a   Krishnan, Monica ^c   Nardo, Luciano G ^d   Pemberton, Philip W ^a  

^a MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^d Reproductive Medicine and Surgery Unit   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MUELLERIAN INHIBITING FACTOR;

BLOOD SAMPLING; BLOOD STORAGE; DILUTION; GOOD LABORATORY PRACTICE; HORMONE BLOOD LEVEL; HORMONE DETERMINATION; HUMAN; INTERMETHOD COMPARISON; LOW TEMPERATURE; MENSTRUAL CYCLE; PRIORITY JOURNAL; REFERENCE VALUE; REVIEW; ROOM TEMPERATURE; STORAGE TEMPERATURE; VALIDATION PROCESS;

ANTI-MULLERIAN HORMONE; BLOOD PRESERVATION; BLOOD SPECIMEN COLLECTION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOASSAY; REPRODUCIBILITY OF RESULTS; TEMPERATURE;

EID: 84895814447     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-3476     Document Type: Review

References (54)

1. Durlinger AL, Kramer P, Karels B, et al. Control of primordial follicle recruitment by anti-Müllerian hormone in the mouse ovary. Endocrinology. 1999;140:5789-5796. (Pubitemid 30645368)
2. Durlinger AL, Gruijters MJ, Kramer P, et al. Anti-Müllerian hormone attenuates the effects of FSH on follicle development in the mouse ovary. Endocrinology. 2001;142:4891-4899. (Pubitemid 33022365)
3. van Rooij IA, Broekmans FJ, te Velde ER, et al. Serum anti-Müllerian hormone levels: a novel measure of ovarian reserve. Hum Reprod. 2002;17:3065-3071. (Pubitemid 35469254)
4. Nelson SM, Yates RW, Fleming R. Serum anti-Müllerian hormone and FSH: prediction of live birth and extremes of response in stimulated cycles-implications for individualization of therapy. Hum Reprod. 2007;22:2414-2421. (Pubitemid 47289055)
5. Nardo LG, Gelbaya TA, Wilkinson H, et al. Circulating basal anti-Müllerian hormone levels as predictor of ovarian response inwomen undergoing ovarian stimulation for in vitro fertilization. Fertil Steril. 2009;92:1586-1593.
6. Yates AP, Rustamov O, Roberts SA, et al. Anti-Mullerian hormone-tailored stimulation protocols improve outcomes whilst reducing adverse effects and costs of IVF. Hum Reprod. 2011;26:2353-2362.
7. Lane AH, Lee MM, Fuller AF Jr, Kehas DJ, Donahoe PK, MacLaughlin DT. Diagnostic utility of Müllerian inhibiting substance determination in patients with primary and recurrent granulosa cell tumors. Gynecol Oncol. 1999;73:51-55. (Pubitemid 29177599)
8. Anderson RA. Pretreatment serum anti-müllerian hormone predicts long-term ovarian function and bone mass after chemotherapy for early breast cancer. J Clin Endocrinol Metab. 2011;96:1336-1343.
9. Broer SL, Eijkemans MJ, Scheffer GJ, et al. Anti-mullerian hormone predicts menopause: a long-term follow-up study in normoovulatory women. J Clin Endocrinol Metab. 2011;96:2532-2539.
10. van Disseldorp J, Lambalk CB, Kwee J, et al. Comparison of interand intra-cycle variability of anti-Mullerian hormone and antral follicle counts. Hum Reprod. 2010;25:221-227.
11. Hudson PL, Dougas I, Donahoe PK, et al. An immunoassay to detect human müllerian inhibiting substance in males and females during normal development. J Clin Endocrinol Metab. 1990;70:16-22.
12. Nelson SM, La Marca A. The journey from the old to the new AMH assay: how to avoid getting lost in the values. Reprod Biomed Online. 2011;23:411-420.
13. Rustamov O, Smith A, Roberts SA, et al. Anti-Mullerian hormone: poor assay reproducibility in a large cohort of subjects suggests sample instability. Hum Reprod. 2012;27:3085-3091.
14. Rustamov O, Smith A, Roberts SA, et al. Author reply: reproducibility of AMH. Hum Reprod. 2012;27:3641-3642.
15. Han X, McShane M, Sahertian R, White C, Ledger W. Pre-mixing samples with assay buffer is an essential pre-requisite for reproducible Antimullerian Hormone (AMH) measurement using the Beckman Coulter Gen II assay (Gen II). Hum Reprod 2013;28(suppl 1):i76 -i78 (abstract).
16. Al-Qahtani A, Muttukrishna S, Appasamy M, et al. Development of a sensitive enzyme immunoassay for anti-Müllerian hormone and the evaluation of potential clinical applications in males and females. Clin Endocrinol (Oxf). 2005;63:267-273. (Pubitemid 41233443)
17. Zhao J, Ng SY, Rivnay B, Leader BS. Serum anti-Müllerian hormone (AMH) measurement: inter-assay agreement and temperature stability. Fertil Steril. 2007;88(suppl 1):S174.
18. Kumar A, Kalra B, Patel A, McDavid L, Roudebush WE. Development of a second generation anti-Müllerian hormone (AMH) ELISA. J Immunol Methods. 2010;362:51-59.
19. Fleming R, Nelson SM. Reproducibility of AMH. Hum Reprod. 2012;27:3639-3641; author reply 3641-3642.
20. Fleming R, Fairbairn C, Blaney C, Lucas D, Gaudoin M. Stability of AMH measurement in blood and avoidance of proteolytic changes. Reprod Biomed Online. 2013;26:130-132.
21. Rey R, Lordereau-Richard I, Carel JC, et al. Anti-müllerian hormone and testosterone serum levels are inversely during normal and precocious pubertal development. J Clin Endocrinol Metab. 1993;77:1220-1226. (Pubitemid 23345473)
22. Long WQ, Ranchin V, Pautier P, et al. Detection of minimal levels of serum anti-Müllerian hormone during follow-up of patients with ovarian granulosa cell tumor by means of a highly sensitive enzyme-linked immunosorbent assay. J Clin Endocrinol Metab. 2000;85:540-544. (Pubitemid 32273631)
23. Preissner CM, Morbeck DE, Gada RP, Grebe SK. Validation of a second generation assay for anti-Mullerian hormone. Clin Chem. 2010;56(suppl):A54.
24. Cappy H, Pigny P, Leroy-Billiard M, Dewailly D, Catteau-Jonard S. Falsely elevated serum antimüllerian hormone level in a context of heterophilic interference. Fertil Steril. 2013;99:1729-1732.
25. Bungum L, Jacobsson AK, Rosén F, et al. Circadian variation in concentration of anti-Müllerian hormone in regularly menstruating females: relation to age, gonadotrophin and sex steroid levels. Hum Reprod. 2011;26:678-684.
26. Cook CL, Siow Y, Taylor S, Fallat ME. Serum müllerian-inhibiting substance levels during normal menstrual cycles. Fertil Steril. 2000;73:859-861. (Pubitemid 30154132)
27. La Marca A, Malmusi S, Giulini S, et al. Anti-Müllerian hormone plasma levels in spontaneous menstrual cycle and during treatment with FSH to induce ovulation. Hum Reprod. 2004;19:2738-2741. (Pubitemid 40028941)
28. La Marca A, Stabile G, Artenisio AC, Volpe A. Serum anti-Mullerian hormone throughout the human menstrual cycle. Hum Reprod. 2006;21:3103-3107. (Pubitemid 44811610)
29. Streuli I, Fraisse T, Chapron C, Bijaoui G, Bischof P, de Ziegler D. Clinical uses of anti-Müllerian hormone assays: pitfalls and promises. Fertil Steril. 2009;91:226-230.
30. Hehenkamp WJ, Looman CW, Themmen AP, de Jong FH, Te Velde ER, Broekmans FJ. Anti-Müllerian hormone levels in the spontaneous menstrual cycle do not show substantial fluctuation. J Clin Endocrinol Metab. 2006;91:4057-4063. (Pubitemid 44536885)
31. Lahlou N, Chabbert-Buffet N, Gainer E, Roger M, Bouchard P. Diphasic pattern of anti-Mullerian hormone (AMH) in ovulatory cycles as evidenced by means of ultra-sensitive assay: new insights into ovarian function. Fertil Steril. 2006;86(suppl):S11.
32. Tsepelidis S, Devreker F, Demeestere I, Flahaut A, Gervy Ch, Englert Y. Stable serum levels of anti-Müllerian hormone during the menstrual cycle: a prospective study in normo-ovulatory women. Hum Reprod. 2007;22:1837-1840. (Pubitemid 47062749)
33. Wunder DM, Bersinger NA, Yared M, Kretschmer R, Birkhäuser MH. Statistically significant changes of antimüllerian hormone and inhibin levels during the physiologic menstrual cycle in reproductive age women. Fertil Steril. 2008;89:927-933. (Pubitemid 351491234)
34. van Disseldorp J, Faddy MJ, Themmen AP, et al. Relationship of serum antimüllerian hormone concentration to age at menopause. J Clin Endocrinol Metab. 2008;93:2129-2134. (Pubitemid 351831526)
35. Sowers M, McConnell D, Gast K, et al. Anti-Müllerian hormone and inhibin B variability during normal menstrual cycles. Fertil Steril. 2010;94:1482-1486.
36. Robertson DM, Hale GE, Fraser IS, Hughes CL, Burger HG. Changes in serum antimüllerian hormone levels across the ovulatory menstrual cycle in late reproductive age. Menopause. 2011;18:521-524.
37. Overbeek A, Broekmans FJ, Hehenkamp WJ, et al. Intra-cycle fluctuations of anti-Müllerian hormone in normalwomenwith a regular cycle: a re-analysis. Reprod Biomed Online. 2012;24:664-669.
38. Roberts SA. Variability in anti-Mullerian hormone levels: a comment on Sowers et al, "Anti-Müllerian hormone and inhibin B variability during normal menstrual cycles." Fertil Steril. 2010;94:e59.
39. Sowers M, McConnell D, Gast K, et al. Author reply: Variability in anti-Mullerian hormone levels: a comment on Sowers et al, "Anti- Müllerian hormone and inhibin B variability during normal menstrual cycles." Fertil Steril. 2010;94:e60.
40. Hadlow N, Longhurst K, McClements A, Natalwala J, Brown SJ, Matson PL. Variation in antimüllerian hormone concentration during the menstrual cycle may change the clinical classification of the ovarian response. Fertil Steril. 2013;99:1791-1797.
41. Fanchin R, Taieb J, Lozano DH, Ducot B, Frydman R, Bouyer J. High reproducibility of serum anti-Mullerian hormone measurements suggests a multi-staged follicular secretion and strengthens its role in the assessment of ovarian follicular status. Hum Reprod. 2005;20:923-927. (Pubitemid 40667836)
42. Dorgan JF, Spittle CS, Egleston BL, Shaw CM, Kahle LL, Brinton LA. Assay reproducibility and within-person variation of Müllerian inhibiting substance. Fertil Steril. 2010;94:301-304.
43. Rustamov O, Pemberton PW, Roberts SA, et al. The reproducibility of serum anti-Müllerian hormone in subfertile women: within and between patient variability. Fertil Steril. 2011;95:1185-1187.
44. Fréour T, Mirallié S, Bach-Ngohou K, Denis M, Barrière P, Masson D. Measurement of serum anti-Müllerian hormone by Beckman Coulter ELISA and DSL ELISA: comparison and relevance in assisted reproduction technology (ART). Clin Chim Acta. 2007;375:162-164. (Pubitemid 44584224)
45. Bersinger NA, Wunder D, Birkhäuser MH, Guibourdenche J. Measurement of anti-mullerian hormone by Beckman Coulter ELISA and DSL ELISA in assisted reproduction: differences between serum and follicular fluid. Clin Chim Acta. 2007;384:174-175. (Pubitemid 47248647)
46. Taieb J, Belville C, Coussieu C, Guibourdenche J, Picard JY, Di clemente N. Two immunoassays for antimullerian hormone measurement: analytical and clinical performances [in French]. Ann Biol Clin (Paris). 2008;66:537-547.
47. Lee JR, Kim SH, Jee BC, Suh CS, Kim KC, Moon SY. Antimüllerian hormone as a predictor of controlled ovarian hyperstimulation outcome: comparison of two commercial immunoassay kits. Fertil Steril. 2011;95:2602-2604.
48. Li HW, Ng EH, Wong BP, Anderson RA, Ho PC, Yeung WS. Correlation between three assay systems for anti-Müllerian hormone (AMH) determination. J Assist Reprod Genet. 2012;29:1443-1446.
49. Pigny P, Dassonneville A, Catteau-Jonard S, Decanter C, Dewailly D. Comparative analysis of two-widely used immunoassays for the measurement of serum AMH in women. Hum Reprod. 2013;28(suppl 1):i311-i316.
50. Gada R, Hughes P, Amols M, et al. Validation and comparison of AMH serum levels using the original active MIS/AMH ELISA to the new active AMH Gen II ELISA. Fertil Steril. 2011;95(suppl):S23.
51. Wallace AM, Faye SA, Fleming R, Nelson SM. A multicentre evaluation of the new Beckman Coulter anti-Mullerian hormone immunoassay (AMH Gen II). Ann Clin Biochem. 2011;48:370-373.
52. The Doctors Laboratory. Lab Report newsletter: Winter 2007/2008. TDL Test Update. Anti-Müllerian Hormone (AMH). http://www.tdlpathology.com/about- tdl/publications/lab-report-newsletter/winter-20072008. Accessed October 2, 2013.
53. Brodin T, Hadziosmanovic N, Berglund L, Olovsson M, Holte J. Antimullerian hormone levels are strongly associated with live birth rates after assisted reproduction. J Clin Endocrinol Metab. 2013;98(3):1107-1104.
54. National Institute for Health and Care Excellence. NICE clinical guideline CG156. Fertility: assessment and treatment for people with fertility problems. http://www.nice.org.uk/Guidance/cg156. Accessed October 2, 2013.