Changes in the clinical impact of high-risk human leukocyte antigen allele mismatch combinations on the outcome of unrelated bone marrow transplantation

Biology of Blood and Marrow Transplantation

Volumn 20, Issue 4, 2014, Pages 526-535

  Kanda, Yoshinobu ^a   Kanda, Junya ^a   Atsuta, Yoshiko ^b   Fuji, Shigeo ^c   Maeda, Yoshinobu ^d   Ichinohe, Tastuo ^e   Takanashi, Minoko ^f   Ohashi, Kazuteru ^g   Fukuda, Takahiro ^c   Miyamura, Koichi ^h   Mori, Takehiko ⁱ   Sao, Hiroshi ^j   Kobayashi, Naoki ^k   Iwato, Koji ^l   Sawada, Akihisa ^m   Mori, Shinichiro ⁿ  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CANCER CENTER HOSPITAL   (Japan)

^d OKAYAMA UNIVERSITY   (Japan)

^e HIROSHIMA UNIVERSITY   (Japan)

^f SUWA RED CROSS HOSPITAL   (Japan)

^g TOKYO METROPOLITAN KOMAGOME HOSPITAL   (Japan)

^h JAPANESE RED CROSS NAGOYA FIRST HOSPITAL   (Japan)

ⁱ KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^j Meitetsu Hospital   (Japan)

^k SAPPORO HOKUYU HOSPITAL   (Japan)

^l ATOMIC BOMB SURVIVORS HOSPITAL   (Japan)

^m RESEARCH INSTITUTE FOR MATERNAL AND CHILD HEALTH   (Japan)

ⁿ ST LUKE'S INTERNATIONAL HOSPITAL   (Japan)

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Author keywords

Bone marrow transplantation; Graft versus host disease; Human leukocyte antigens; Leukemia

Indexed keywords

CYCLOSPORIN A; HLA ANTIGEN; TACROLIMUS;

ACUTE GRAFT VERSUS HOST DISEASE; ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE MYELOBLASTIC LEUKEMIA; ADULT; ALLELE; ARTICLE; BONE MARROW TRANSPLANTATION; CANCER PATIENT; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GRAFT RECIPIENT; GRAFT VERSUS HOST REACTION; HAZARD RATIO; HIGH RISK HLA ALLELE MISMATCH; HIGH RISK PATIENT; HISTOCOMPATIBILITY; HLA MATCHING; HLA SYSTEM; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LOW RISK POPULATION; MAJOR CLINICAL STUDY; MALE; MYELODYSPLASTIC SYNDROME; OPERATION DURATION; OVERALL SURVIVAL; SURGICAL RISK; TREATMENT OUTCOME; UNRELATED DONORS; WHOLE BODY RADIATION;

BONE MARROW TRANSPLANTATION; GRAFT-VERSUS-HOST DISEASE; HUMAN LEUKOCYTE ANTIGENS; LEUKEMIA;

ADOLESCENT; ADULT; AGE FACTORS; ALLELES; FEMALE; GENE EXPRESSION; GRAFT VS HOST DISEASE; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; MALE; RISK; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; TIME FACTORS; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME; UNRELATED DONORS;

EID: 84895790901     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2014.01.003     Document Type: Article

References (14)

1. Flomenberg N., Baxter-Lowe L.A., Confer D., et al. Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. Blood 2004, 104:1923-1930.
2. Lee S.J., Klein J., Haagenson M., et al. High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation. Blood 2007, 110:4576-4583.
3. Petersdorf E.W., Anasetti C., Martin P.J., et al. Limits of HLA mismatching in unrelated hematopoietic cell transplantation. Blood 2004, 104:2976-2980.
4. Sasazuki T., Juji T., Morishima Y., et al. Effect of matching of class I HLA alleles on clinical outcome after transplantation of hematopoietic stem cells from an unrelated donor. Japan Marrow Donor Program. NEngl J Med 1998, 339:1177-1185.
5. Kanda Y., Kanda J., Atsuta Y., et al. Impact of a single human leucocyte antigen (HLA) allele mismatch on the outcome of unrelated bone marrow transplantation over two time periods. A retrospective analysis of 3003 patients from the HLA Working Group of the Japan Society for Blood and Marrow Transplantation. Br J Haematol 2013, 161:566-577.
6. Zino E., Frumento G., Marktel S., et al. AT-cell epitope encoded by a subset of HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation. Blood 2004, 103:1417-1424.
7. Kawase T., Morishima Y., Matsuo K., et al. High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism. Blood 2007, 110:2235-2241.
8. Atsuta Y., Suzuki R., Yoshimi A., et al. Unification of hematopoietic stem cell transplantation registries in Japan and establishment of the TRUMP System. Int J Hematol 2007, 86:269-274.
9. Morishima Y., Sasazuki T., Inoko H., et al. The clinical significance of human leukocyte antigen (HLA) allele compatibility in patients receiving a marrow transplant from serologically HLA-A, HLA-B, and HLA-DR matched unrelated donors. Blood 2002, 99:4200-4206.
10. Gray R.J. Aclass of k-sample tests for comparing the cumulative incidence of a competing risk. Ann Stat 1988, 16:1141-1154.
11. Fine J.P., Gray R.J. Aproportional hazards model for subdistribution of a competing risk. JAm Stat Assoc 1999, 94:456-509.
12. Kanda Y. Investigation of the freely available easy-to-use software "EZR" (Easy R) for medical statistics. Bone Marrow Transplant 2013, 48:452-458.
13. Morishima Y., Yabe T., Matsuo K., et al. Effects of HLA allele and killer immunoglobulin-like receptor ligand matching on clinical outcome in leukemia patients undergoing transplantation with T-cell-replete marrow from an unrelated donor. Biol Blood Marrow Transplant 2007, 13:315-328.
14. Leung W. Use of NK cell activity in cure by transplant. Br J Haematol 2011, 155:14-29.