Enzyme reaction kinetics, metabolic enzyme phenotype, and metabolites of berberine

Chinese Traditional and Herbal Drugs

Volumn 44, Issue 23, 2013, Pages 3334-3340

  Chen, Jian Long ^a,b   Zhang, Yu Ling ^a,b   Dong, Yu ^b   Zhang, Lei ^a   Liu, Dan ^a   Yang, Jian Long ^a   Cai, Guang Zhi ^a   Gong, Ji Yu ^a   Cui, Han Ming ^b  

^a CHANGCHUN UNIVERSITY   (China)

^b INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Berberine; Berberrubine; Demethyleneberberine; Metabolic pathway; Metabolites; Pooled human liver microsomes; Recombinant human cytochrome enzyme P450 isozyme; Thalifendine

Indexed keywords

BERBERINE; BEROLINE; CYTOCHROME P450 1A2; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 ISOENZYME; FURAFYLLINE; THALIFENDINE;

ARTICLE; CHEMICAL STRUCTURE; CLEARANCE; ENZYME KINETICS; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; METABOLISM; METABOLITE; MICHAELIS MENTEN KINETICS; PHENOTYPE; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VELOCITY;

EID: 84895788783     PISSN: 02532670     EISSN: None     Source Type: Journal    
DOI: 10.7501/j.issn.0253-2670.2013.23.014     Document Type: Article

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