New insights provided by a comparison of impaired deformability with erythrocyte oxidative stress for sickle cell disease

Blood Cells, Molecules, and Diseases

Volumn 52, Issue 4, 2014, Pages 230-235

  Barodka, Viachaslau M ^a   Nagababu, Enika ^b   Mohanty, Joy G ^b   Nyhan, Daniel ^a   Berkowitz, Dan E ^a   Rifkind, Joseph M ^b   Strouse, John J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Deformability; Erythrocytes; Fluorescence; Heme degradation; Hemoglobin; Sickle cell disease

Indexed keywords

HEMOGLOBIN; HEMOPROTEIN;

ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE SEVERITY; ERYTHROCYTE DEFORMABILITY; HUMAN; MOLECULAR PATHOLOGY; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN POLYMORPHISM; QUANTITATIVE ANALYSIS; SICKLE CELL ANEMIA;

DEFORMABILITY; ERYTHROCYTES; FLUORESCENCE; HEME DEGRADATION; HEMOGLOBIN; SICKLE CELL DISEASE;

ADOLESCENT; ADULT; ANEMIA, SICKLE CELL; CHILD; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTES; ERYTHROCYTES, ABNORMAL; FEMALE; FETAL HEMOGLOBIN; HEME; HEMOGLOBIN, SICKLE; HEMOGLOBINS; HUMANS; MALE; OXIDATIVE STRESS; PROTEOLYSIS; SICKLE CELL TRAIT; YOUNG ADULT;

EID: 84895548557     PISSN: 10799796     EISSN: 10960961     Source Type: Journal    
DOI: 10.1016/j.bcmd.2013.10.004     Document Type: Article

References (38)

1. Ajmani R.S., Fleg J.L., Demehin A.A., et al. Oxidative stress and hemorheological changes induced by acute treadmill exercise. Clin. Hemorheol. Microcirc. 2003, 28:29-40.
2. Akinola N.O., Stevens S.M., Franklin I.M., et al. Rheological changes in the prodromal and established phases of sickle cell vaso-occlusive crisis. Br. J. Haematol. 1992, 81:598-602.
3. Baldeiras I., Santana I., Proenca M.T., et al. Peripheral oxidative damage in mild cognitive impairment and mild Alzheimer's disease. J. Alzheimers Dis. 2008, 15:117-128.
4. Ballas S.K. Sickle cell anemia with few painful crises is characterized by decreased red cell deformability and increased number of dense cells. Am. J. Hematol. 1991, 36:122-130.
5. Ballas S.K., Smith E.D. Red blood cell changes during the evolution of the sickle cell painful crisis. Blood 1992, 79:2154-2163.
6. Barabino G.A., Platt M.O., Kaul D.K. Sickle cell biomechanics. Annu. Rev. Biomed. Eng. 2010, 12:345-367.
7. Baskurt O.K., Boynard M., Cokelet G.C., et al. New guidelines for hemorheological laboratory techniques. Clin. Hemorheol. Microcirc. 2009, 42:75-97.
8. Brugnara C. Membrane transport of Na and K and cell dehydration in sickle erythrocytes. Experientia 1993, 49:100-109.
9. Bunn H.F. Pathogenesis and treatment of sickle cell disease. N. Engl. J. Med. 1997, 337:762-769.
10. Caimi G. Erythrocyte peroxide metabolism, plasma lipid pattern and hemorheological profile in chronic renal failure. J. Nephrol. 2002, 15:104-108.
11. Canessa M. Red cell volume-related ion transport systems in hemoglobinopathies. Hematol. Oncol. Clin. N. Am. 1991, 5:495-516.
12. Connes P., Hue O., Tripette J., Hardy-Dessources M.D. Blood rheology abnormalities and vascular cell adhesion mechanisms in sickle cell trait carriers during exercise. Clin. Hemorheol. Microcirc. 2008, 39:179-184.
13. Connor J., Pak C.C., Schroit A.J. Exposure of phosphatidylserine in the outer leaflet of human red blood cells. Relationship to cell density, cell age, and clearance by mononuclear cells. J. Biol. Chem. 1994, 269:2399-2404.
14. Giulivi C., Hochstein P., Davies K.J. Hydrogen peroxide production by red blood cells. Free Radic. Biol. Med. 1994, 16:123-129.
15. Hebbel R.P. The sickle erythrocyte in double jeopardy: autoxidation and iron decompartmentalization. Semin. Hematol. 1990, 27:51-69.
16. Hebbel R.P. Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology. Blood 1991, 77:214-237.
17. Kaul D.K., Liu X.D., Chang H.Y., et al. Effect of fetal hemoglobin on microvascular regulation in sickle transgenic-knockout mice. J. Clin. Invest. 2004, 114:1136-1145.
18. Lew V.L., Bookchin R.M. Osmotic effects of protein polymerization: analysis of volume changes in sickle cell anemia red cells following deoxy-hemoglobin S polymerization. J. Membr. Biol. 1991, 122:55-67.
19. Lew V.L., Bookchin R.M. Ion transport pathology in the mechanism of sickle cell dehydration. Physiol. Rev. 2005, 85:179-200.
20. Misra H.P., Fridovich I. The generation of superoxide radical during the autoxidation of hemoglobin. J. Biol. Chem. 1972, 247:6960-6962.
21. Mohandas N., Chasis J.A., Shohet S.B. The influence of membrane skeleton on red cell deformability, membrane material properties, and shape. Semin. Hematol. 1983, 20:225-242.
22. Mohandas N., Phillips W.M., Bessis M. Red blood cell deformability and hemolytic anemias. Semin. Hematol. 1979, 16:95-114.
23. Mohandas N., Hebbel R.P. Erythrocyte deformability, fragility and rheology. Sickle Cell Disease 1994, 205-216. Raven Press, New York. S.H. Embury, R.P. Hebbel, N. Mohandas, M.H. Steinberg (Eds.).
24. Mundee Y., Bigelow N.C., Davis B.H., Porter J.B. Flow cytometric method for simultaneous assay of foetal haemoglobin containing red cells, reticulocytes and foetal haemoglobin containing reticulocytes. Clin. Lab. Haematol. 2001, 23:149-154.
25. Nagababu E., Chrest F.J., Rifkind J.M. The origin of red cell fluorescence caused by hydrogen peroxide treatment. Free Radic. Biol. Med. 2000, 29:659-663.
26. Nagababu E., Fabry M.E., Nagel R.L., Rifkind J.M. Heme degradation and oxidative stress in murine models for hemoglobinopathies: thalassemia, sickle cell disease and hemoglobin C disease. Blood Cells Mol. Dis. 2008, 41:60-66.
27. Nagababu E., Gulyani S., Earley C.J., et al. Iron-deficiency anaemia enhances red blood cell oxidative stress. Free Radic. Res. 2008, 42:824-829.
28. Nagababu E., Mohanty J.G., Bhamidipaty S., et al. Role of the membrane in the formation of heme degradation products in red blood cells. Life Sci. 2010, 86:133-138.
29. Nagababu E., Rifkind J.M. Formation of fluorescent heme degradation products during the oxidation of hemoglobin by hydrogen peroxide. Biochem. Biophys. Res. Commun. 1998, 247:592-596.
30. Nagababu E., Rifkind J.M. Heme degradation during autoxidation of oxyhemoglobin. Biochem. Biophys. Res. Commun. 2000, 273:839-845.
31. Nagababu E., Rifkind J.M. Heme degradation by reactive oxygen species. Antioxid. Redox Signal. 2004, 6:967-978.
32. Piccinini G., Minetti G., Balduini C., Brovelli A. Oxidation state of glutathione and membrane proteins in human red cells of different age. Mech. Ageing Dev. 1995, 78:15-26.
33. Polat G., Tamer L., Tanriverdi K., et al. Levels of malondialdehyde, glutathione and ascorbic acid in idiopathic thrombocytopaenic purpura. East Afr. Med. J. 2002, 79:446-449.
34. Shaklai N., Sharma V.S., Ranney H.M. Interaction of sickle cell hemoglobin with erythrocyte membranes. Proc. Natl. Acad. Sci. U. S. A. 1981, 78:65-68.
35. Sheng K., Shariff M., Hebbel R.P. Comparative oxidation of hemoglobins A and S. Blood 1998, 91:3467-3470.
36. Shin S., Hou J.X., Suh J.S., Singh M. Validation and application of a microfluidic ektacytometer (RheoScan-D) in measuring erythrocyte deformability. Clin. Hemorheol. Microcirc. 2007, 37:319-328.
37. Wegner G., Kucera W., Lerche D. Investigations on the deformability of human red blood cells stored in different preservative solutions: influence of changed medium composition. Biomed. Biochim. Acta 1987, 46:605-609.
38. Winterbourn C.C. Oxidative denaturation in congenital hemolytic anemias: the unstable hemoglobins. Semin. Hematol. 1990, 27:41-50.