메뉴 건너뛰기




Volumn 35, Issue 3, 2014, Pages 311-315

Neuronal nicotinic acetylcholine receptors are important targets for alcohol reward and dependence

Author keywords

abused substance; alcoholism; ethanol reward and dependence; mesolimbic dopamine system; nicotine; nicotinic acetylcholine receptor; smoking

Indexed keywords

ACAMPROSATE; ALCOHOL; CP 601932; CYTISINE; DISULFIRAM; LOBELINE; LOBELINE MECAMYLAMINE; MECAMYLAMINE; NALTREXONE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; PF 4575180; SAZETIDINE A; UNCLASSIFIED DRUG; VARENICLINE; DRUGS USED IN THE TREATMENT OF ADDICTION;

EID: 84895545435     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.181     Document Type: Review
Times cited : (31)

References (50)
  • 1
  • 2
    • 79961060508 scopus 로고    scopus 로고
    • World Health Organization Editors. Geneva, Switzerland: World Health Organization
    • World Health Organization Editors. Global status report on noncommunicable diseases. Geneva, Switzerland: World Health Organization; 2010.
    • (2010) Global Status Report on Noncommunicable Diseases
  • 4
    • 58349118731 scopus 로고    scopus 로고
    • Neurobiology of alcohol dependence: Focus on motivational mechanisms
    • Gilpin NW, Koob GF. Neurobiology of alcohol dependence: focus on motivational mechanisms. Alcohol Res Health 2008; 31: 185-95.
    • (2008) Alcohol Res Health , vol.31 , pp. 185-195
    • Gilpin, N.W.1    Koob, G.F.2
  • 6
    • 33644875171 scopus 로고    scopus 로고
    • Binge drinking and mortality after acute myocardial infarction
    • Mukamal KJ, Maclure M, Muller JE, Mittleman MA. Binge drinking and mortality after acute myocardial infarction. Circulation 2005; 112: 3839-45.
    • (2005) Circulation , vol.112 , pp. 3839-3845
    • Mukamal, K.J.1    MacLure, M.2    Muller, J.E.3    Mittleman, M.A.4
  • 8
    • 77956163104 scopus 로고    scopus 로고
    • Ethanol action on dopaminergic neurons in the ventral tegmental area: Interaction with intrinsic ion channels and neurotransmitter inputs
    • Morikawa H, Morrisett RA. Ethanol action on dopaminergic neurons in the ventral tegmental area: interaction with intrinsic ion channels and neurotransmitter inputs. Int Rev Neurobiol 2010; 91: 235-88.
    • (2010) Int Rev Neurobiol , vol.91 , pp. 235-288
    • Morikawa, H.1    Morrisett, R.A.2
  • 9
    • 84894096256 scopus 로고    scopus 로고
    • Association of gamma-aminobutyric acid a receptor α 2 gene (GABRA2) with alcohol use disorder
    • doi: 10.1038/npp.2013.291
    • Li D, Sulovari A, Cheng C, Zhao H, Kranzler HR, Gelernter J. Association of gamma-aminobutyric acid a receptor α 2 gene (GABRA2) with alcohol use disorder. Neuropsychopharmacology 2013; doi: 10.1038/npp.2013.291.
    • (2013) Neuropsychopharmacology
    • Li, D.1    Sulovari, A.2    Cheng, C.3    Zhao, H.4    Kranzler, H.R.5    Gelernter, J.6
  • 10
    • 0029879993 scopus 로고    scopus 로고
    • Addictive drugs and brain stimulation reward
    • Wise RA. Addictive drugs and brain stimulation reward. Annu Rev Neurosci 1996; 19: 319-40.
    • (1996) Annu Rev Neurosci , vol.19 , pp. 319-340
    • Wise, R.A.1
  • 11
    • 0017122866 scopus 로고
    • Alcoholism, cigarette smoking, coffee drinking and extraversion
    • Ayers J, Ruff CF, Templer DI. Alcoholism, cigarette smoking, coffee drinking and extraversion. J Stud Alcohol 1976; 37: 983-5.
    • (1976) J Stud Alcohol , vol.37 , pp. 983-985
    • Ayers, J.1    Ruff, C.F.2    Templer, D.I.3
  • 12
    • 11844276603 scopus 로고    scopus 로고
    • Neuronal nicotinic receptors: From structure to pathology
    • Gotti C, Clementi F. Neuronal nicotinic receptors: from structure to pathology. Prog Neurobiol 2004; 74: 363-96.
    • (2004) Prog Neurobiol , vol.74 , pp. 363-396
    • Gotti, C.1    Clementi, F.2
  • 13
    • 80052037658 scopus 로고    scopus 로고
    • Naturally-expressed nicotinic acetylcholine receptor subtypes
    • Wu J, Lukas RJ. Naturally-expressed nicotinic acetylcholine receptor subtypes. Biochem Pharmacol 2011; 82: 800-7.
    • (2011) Biochem Pharmacol , vol.82 , pp. 800-807
    • Wu, J.1    Lukas, R.J.2
  • 14
    • 33748895080 scopus 로고    scopus 로고
    • Roles of nicotinic acetylcholine receptor beta subunits in function of human alpha4-containing nicotinic receptors
    • Wu J, Liu Q, Yu K, Hu J, Kuo YP, Segerberg M, et al. Roles of nicotinic acetylcholine receptor beta subunits in function of human alpha4-containing nicotinic receptors. J Physiol 2006; 576: 103-18.
    • (2006) J Physiol , vol.576 , pp. 103-118
    • Wu, J.1    Liu, Q.2    Yu, K.3    Hu, J.4    Kuo, Y.P.5    Segerberg, M.6
  • 15
    • 0035282788 scopus 로고    scopus 로고
    • Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei
    • Klink R, de Kerchove d'Exaerde A, Zoli M, Changeux JP. Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei. J Neurosci 2001; 21: 1452-63.
    • (2001) J Neurosci , vol.21 , pp. 1452-1463
    • Klink, R.1    De Kerchove D'Exaerde, A.2    Zoli, M.3    Changeux, J.P.4
  • 17
    • 0027438502 scopus 로고
    • The mesolimbic dopamine-activating properties of ethanol are antagonized by mecamylamine
    • Blomqvist O, Engel JA, Nissbrandt H, Soderpalm B. The mesolimbic dopamine-activating properties of ethanol are antagonized by mecamylamine. Eur J Pharmacol 1993; 249: 207-13.
    • (1993) Eur J Pharmacol , vol.249 , pp. 207-213
    • Blomqvist, O.1    Engel, J.A.2    Nissbrandt, H.3    Soderpalm, B.4
  • 18
    • 0030608347 scopus 로고    scopus 로고
    • Voluntary ethanol intake in the rat: Effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment
    • Blomqvist O, Ericson M, Johnson DH, Engel JA, Soderpalm B. Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment. Eur J Pharmacol 1996; 314: 257-67.
    • (1996) Eur J Pharmacol , vol.314 , pp. 257-267
    • Blomqvist, O.1    Ericson, M.2    Johnson, D.H.3    Engel, J.A.4    Soderpalm, B.5
  • 19
    • 36348949690 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors in the ventral tegmental area mediate the dopamine activating and reinforcing properties of ethanol cues
    • Löf E, Olausson P, deBejczy A, Stomberg R, McIntosh JM, Taylor JR, et al. Nicotinic acetylcholine receptors in the ventral tegmental area mediate the dopamine activating and reinforcing properties of ethanol cues. Psychopharmacology 2007; 195: 333-43.
    • (2007) Psychopharmacology , vol.195 , pp. 333-343
    • Löf, E.1    Olausson, P.2    Debejczy, A.3    Stomberg, R.4    McIntosh, J.M.5    Taylor, J.R.6
  • 20
    • 60549110829 scopus 로고    scopus 로고
    • Effects of subunit selective nACh receptors on operant ethanol self-administration and relapse-like ethanol-drinking behavior
    • Kuzmin A, Jerlhag E, Liljequist S, Engel J. Effects of subunit selective nACh receptors on operant ethanol self-administration and relapse-like ethanol-drinking behavior. Psychopharmacology 2009; 203: 99-108.
    • (2009) Psychopharmacology , vol.203 , pp. 99-108
    • Kuzmin, A.1    Jerlhag, E.2    Liljequist, S.3    Engel, J.4
  • 21
    • 67349161456 scopus 로고    scopus 로고
    • Modulation of ethanol drinking-in-The-dark by mecamylamine and nicotinic acetylcholine receptor agonists in C57BL/6J mice
    • Hendrickson LM, Zhao-Shea R, Tapper AR. Modulation of ethanol drinking-in-the-dark by mecamylamine and nicotinic acetylcholine receptor agonists in C57BL/6J mice. Psychopharmacology 2009; 204: 563-72.
    • (2009) Psychopharmacology , vol.204 , pp. 563-572
    • Hendrickson, L.M.1    Zhao-Shea, R.2    Tapper, A.R.3
  • 22
    • 66049160668 scopus 로고    scopus 로고
    • Effects of mecamylamine on alcohol consumption and preference in male C57BL/6J mice
    • Farook JM, Lewis B, Gaddis JG, Littleton JM, Barron S. Effects of mecamylamine on alcohol consumption and preference in male C57BL/6J mice. Pharmacology 2009; 83: 379-84.
    • (2009) Pharmacology , vol.83 , pp. 379-384
    • Farook, J.M.1    Lewis, B.2    Gaddis, J.G.3    Littleton, J.M.4    Barron, S.5
  • 23
    • 84885607317 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors containing the alpha6 subunit contribute to ethanol activation of ventral tegmental area dopaminergic neurons
    • Liu L, Zhao-Shea R, McIntosh JM, Tapper AR. Nicotinic acetylcholine receptors containing the alpha6 subunit contribute to ethanol activation of ventral tegmental area dopaminergic neurons. Biochem Pharmacol 2013; 86: 1194-200.
    • (2013) Biochem Pharmacol , vol.86 , pp. 1194-1200
    • Liu, L.1    Zhao-Shea, R.2    McIntosh, J.M.3    Tapper, A.R.4
  • 24
    • 84856490958 scopus 로고    scopus 로고
    • Acquisition, expression, and reinstatement of ethanol-induced conditioned place preference in mice: Effects of exposure to stress and modulation by mecamylamine
    • Bhutada P, Mundhada Y, Ghodki Y, Dixit P, Umathe S, Jain K. Acquisition, expression, and reinstatement of ethanol-induced conditioned place preference in mice: effects of exposure to stress and modulation by mecamylamine. J Psychopharmacol 2012; 26: 315-23.
    • (2012) J Psychopharmacol , vol.26 , pp. 315-323
    • Bhutada, P.1    Mundhada, Y.2    Ghodki, Y.3    Dixit, P.4    Umathe, S.5    Jain, K.6
  • 25
    • 0037466294 scopus 로고    scopus 로고
    • Ethanol elevates accumbal dopamine levels via indirect activation of ventral tegmental nicotinic acetylcholine receptors
    • Ericson M, Molander A, Lof E, Engel JA, Soderpalm B. Ethanol elevates accumbal dopamine levels via indirect activation of ventral tegmental nicotinic acetylcholine receptors. Eur J Pharmacol 2003; 467: 85-93.
    • (2003) Eur J Pharmacol , vol.467 , pp. 85-93
    • Ericson, M.1    Molander, A.2    Lof, E.3    Engel, J.A.4    Soderpalm, B.5
  • 26
    • 14344260723 scopus 로고    scopus 로고
    • Is an alpha-conotoxin MII-sensitive mechanism involved in the neurochemical, stimulatory, and rewarding effects of ethanol?
    • Larsson A, Jerlhag E, Svensson L, Soderpalm B, Engel JA. Is an alpha-conotoxin MII-sensitive mechanism involved in the neurochemical, stimulatory, and rewarding effects of ethanol? Alcohol 2004; 34: 239-50.
    • (2004) Alcohol , vol.34 , pp. 239-250
    • Larsson, A.1    Jerlhag, E.2    Svensson, L.3    Soderpalm, B.4    Engel, J.A.5
  • 27
    • 77649238318 scopus 로고    scopus 로고
    • Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice
    • Kamens HM, Andersen J, Picciotto MR. Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice. Psychopharmacology 2010; 208: 613-26.
    • (2010) Psychopharmacology , vol.208 , pp. 613-626
    • Kamens, H.M.1    Andersen, J.2    Picciotto, M.R.3
  • 28
    • 84863094881 scopus 로고    scopus 로고
    • The alpha6 nicotinic acetylcholine receptor subunit influences ethanol-induced sedation
    • Kamens HM, Hoft NR, Cox RJ, Miyamoto JH, Ehringer MA. The alpha6 nicotinic acetylcholine receptor subunit influences ethanol-induced sedation. Alcohol 2012; 46: 463-71.
    • (2012) Alcohol , vol.46 , pp. 463-471
    • Kamens, H.M.1    Hoft, N.R.2    Cox, R.J.3    Miyamoto, J.H.4    Ehringer, M.A.5
  • 29
    • 84875644942 scopus 로고    scopus 로고
    • The alpha5 neuronal nicotinic acetylcholine receptor subunit plays an important role in the sedative effects of ethanol but does not modulate consumption in mice
    • Santos N, Chatterjee S, Henry A, Holgate J, Bartlett SE. The alpha5 neuronal nicotinic acetylcholine receptor subunit plays an important role in the sedative effects of ethanol but does not modulate consumption in mice. Alcohol Clin Exp Res 2013; 37: 655-62.
    • (2013) Alcohol Clin Exp Res , vol.37 , pp. 655-662
    • Santos, N.1    Chatterjee, S.2    Henry, A.3    Holgate, J.4    Bartlett, S.E.5
  • 30
    • 77955403546 scopus 로고    scopus 로고
    • Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption
    • Hendrickson LM, Zhao-Shea R, Pang X, Gardner PD, Tapper AR. Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption. J Neurosci 2010; 30: 10169-76.
    • (2010) J Neurosci , vol.30 , pp. 10169-10176
    • Hendrickson, L.M.1    Zhao-Shea, R.2    Pang, X.3    Gardner, P.D.4    Tapper, A.R.5
  • 33
    • 84901234557 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors in the ventral tegmental area are important targets for nicotine and ethanol co-dependence
    • doi:10.4172/2167-0501.S1-002
    • Taylor DH, Steffensen SC, Wu J. Nicotinic acetylcholine receptors in the ventral tegmental area are important targets for nicotine and ethanol co-dependence. Biochem Pharmacol 2013; doi:10.4172/2167-0501.S1-002.
    • (2013) Biochem Pharmacol
    • Taylor, D.H.1    Steffensen, S.C.2    Wu, J.3
  • 34
    • 0030175612 scopus 로고    scopus 로고
    • Nicotinic receptors in the development and modulation of CNS synapses
    • Role LW, Berg DK. Nicotinic receptors in the development and modulation of CNS synapses. Neuron 1996; 16: 1077-85.
    • (1996) Neuron , vol.16 , pp. 1077-1085
    • Role, L.W.1    Berg, D.K.2
  • 35
    • 84901234557 scopus 로고    scopus 로고
    • Nicotine enhances the excitability of gaba neurons in the ventral tegmental area via activation of alpha 7 nicotinic receptors on glutamate terminals
    • Taylor DH, Burman PN, Hansen MD, Wilcox RS, Larsen BR, Blanchard JK, et al. Nicotine enhances the excitability of gaba neurons in the ventral tegmental area via activation of alpha 7 nicotinic receptors on glutamate terminals. Biochem Pharmacol 2013; S1-007.
    • (2013) Biochem Pharmacol
    • Taylor, D.H.1    Burman, P.N.2    Hansen, M.D.3    Wilcox, R.S.4    Larsen, B.R.5    Blanchard, J.K.6
  • 36
    • 0031032949 scopus 로고    scopus 로고
    • Presynaptic nicotinic ACh receptors
    • Wonnacott S. Presynaptic nicotinic ACh receptors. Trends Neurosci 1997; 20: 92-8.
    • (1997) Trends Neurosci , vol.20 , pp. 92-98
    • Wonnacott, S.1
  • 37
    • 63849158510 scopus 로고    scopus 로고
    • Acute alcohol action and desensitization of ligand-gated ion channels
    • Dopico AM, Lovinger DM. Acute alcohol action and desensitization of ligand-gated ion channels. Pharmacol Rev 2009; 61: 98-114.
    • (2009) Pharmacol Rev , vol.61 , pp. 98-114
    • Dopico, A.M.1    Lovinger, D.M.2
  • 38
    • 0030824009 scopus 로고    scopus 로고
    • Accumbal dopamine overflow after ethanol: Localization of the antagonizing effect of mecamylamine
    • Blomqvist O, Ericson M, Engel JA, Soderpalm B. Accumbal dopamine overflow after ethanol: localization of the antagonizing effect of mecamylamine. Eur J Pharmacol 1997; 334: 149-56.
    • (1997) Eur J Pharmacol , vol.334 , pp. 149-156
    • Blomqvist, O.1    Ericson, M.2    Engel, J.A.3    Soderpalm, B.4
  • 39
    • 0033011345 scopus 로고    scopus 로고
    • Unrestricted free-choice ethanol self-administration in rats causes long-term neuroadaptations in the nucleus accumbens and caudate putamen
    • Nestby P, Vanderschuren LJ, De Vries TJ, Mulder AH, Wardeh G, Hogenboom F, et al. Unrestricted free-choice ethanol self-administration in rats causes long-term neuroadaptations in the nucleus accumbens and caudate putamen. Psychopharmacology 1999; 141: 307-14.
    • (1999) Psychopharmacology , vol.141 , pp. 307-314
    • Nestby, P.1    Vanderschuren, L.J.2    De Vries, T.J.3    Mulder, A.H.4    Wardeh, G.5    Hogenboom, F.6
  • 40
    • 0032500881 scopus 로고    scopus 로고
    • Voluntary ethanol intake in the rat and the associated accumbal dopamine overflow are blocked by ventral tegmental mecamylamine
    • Ericson M, Blomqvist O, Engel JA, Soderpalm B. Voluntary ethanol intake in the rat and the associated accumbal dopamine overflow are blocked by ventral tegmental mecamylamine. Eur J Pharmacol 1998; 358: 189-96.
    • (1998) Eur J Pharmacol , vol.358 , pp. 189-196
    • Ericson, M.1    Blomqvist, O.2    Engel, J.A.3    Soderpalm, B.4
  • 41
  • 43
    • 0032895274 scopus 로고    scopus 로고
    • Ethanol modulation of nicotinic acetylcholine receptor currents in cultured cortical neurons
    • Aistrup GL, Marszalec W, Narahashi T. Ethanol modulation of nicotinic acetylcholine receptor currents in cultured cortical neurons. Mol Pharmacol 1999; 55: 39-49.
    • (1999) Mol Pharmacol , vol.55 , pp. 39-49
    • Aistrup, G.L.1    Marszalec, W.2    Narahashi, T.3
  • 44
    • 0025061018 scopus 로고
    • Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitro
    • Brodie MS, Shefner SA, Dunwiddie TV. Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitro. Brain Res 1990; 508: 65-9.
    • (1990) Brain Res , vol.508 , pp. 65-69
    • Brodie, M.S.1    Shefner, S.A.2    Dunwiddie, T.V.3
  • 45
    • 0031885254 scopus 로고    scopus 로고
    • The effects of ethanol on dopaminergic neurons of the ventral tegmental area studied with intracellular recording in brain slices
    • Brodie MS, Appel SB. The effects of ethanol on dopaminergic neurons of the ventral tegmental area studied with intracellular recording in brain slices. Alcohol Clin Exp Res 1998; 22: 236-44.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 236-244
    • Brodie, M.S.1    Appel, S.B.2
  • 48
    • 33744531492 scopus 로고    scopus 로고
    • Effect of oral acamprosate on abstinence in patients with alcohol dependence in a double-blind, placebo-controlled trial: The role of patient motivation
    • Mason BJ, Goodman AM, Chabac S, Lehert P. Effect of oral acamprosate on abstinence in patients with alcohol dependence in a double-blind, placebo-controlled trial: the role of patient motivation. J Psychiatr Res 2006; 40: 383-93.
    • (2006) J Psychiatr Res , vol.40 , pp. 383-393
    • Mason, B.J.1    Goodman, A.M.2    Chabac, S.3    Lehert, P.4
  • 49
    • 67649985942 scopus 로고    scopus 로고
    • Alcoholism: A systems approach from molecular physiology to addictive behavior
    • Spanagel R. Alcoholism: a systems approach from molecular physiology to addictive behavior. Physiol Rev s 2009; 89: 649-705.
    • (2009) Physiol Rev S , vol.89 , pp. 649-705
    • Spanagel, R.1
  • 50
    • 84861757581 scopus 로고    scopus 로고
    • Cholinergic receptor system as a target for treating alcohol abuse and dependence
    • Rahman S, Prendergast MA. Cholinergic receptor system as a target for treating alcohol abuse and dependence. Recent Pat CNS Drug Discov 2012; 7: 145-50.
    • (2012) Recent Pat CNS Drug Discov , vol.7 , pp. 145-150
    • Rahman, S.1    Prendergast, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.