Increased heart attacks in men using testosterone: The UK importantly lags far behind the US in prescribing testosterone

BMJ (Online)

Volumn 348, Issue , 2014, Pages

  Wolfe, Sidney M ^a  

^a Public Citizen Health Research Group   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TESTOSTERONE DERIVATIVE;

BLOOD EXAMINATION; CARDIOVASCULAR RISK; DRUG APPROVAL; DRUG MARKETING; FATIGUE; FOOD AND DRUG ADMINISTRATION; HEART INFARCTION; HORMONE DETERMINATION; HUMAN; MALE; PRESCRIPTION; PRIORITY JOURNAL; PUBLIC HEALTH; SHORT SURVEY; TREATMENT INDICATION; UNITED KINGDOM; UNITED STATES;

AGED; DRUG APPROVAL; DRUG LABELING; DRUG PRESCRIPTIONS; GREAT BRITAIN; HUMANS; MALE; MYOCARDIAL INFARCTION; RISK FACTORS; TESTOSTERONE; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 84895543935     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.g1789     Document Type: Short Survey

References (9)

1. Public Citizen petition. www.citizen.org/hrg2184.
2. Xu L, Freeman G, Cowling BJ, Schooling CM. Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled trials. BMC Medicine 2013;11:108.
3. Letter to Guido Rasi, executive director of the European Medicines Agency, from Public Citizen. 2014. www.citizen.org/hrg2186.
4. Finkle, WD, Greenland S, Ridgeway GK, Adams JL, Frasco MA, Hoover RN. Increased risks of non-fatal myocardial infarction following testosterone therapy prescription in men. Plos One 2014, doi:10.1371/journal.pone.0085805.
5. Basaria S, Coviello AD, Travison TG, Storer TW, Farwell WR, Jette AM, et al. Adverse events associated with testosterone administration. N Engl J Med 2010;363:109-22.
6. US Food and Drug Administration. FDA evaluating risk of stroke, heart attack and death with FDA-approved testosterone products. 31 January 2014. www.fda.gov/Drugs/DrugSafety/ucm383904.htm.
7. Avorn, JA. Powerful medicines: the benefits, risks and costs of prescription medicines . Vintage Books, 2005.
8. Baillargeon J, Urban RJ, Ottenbacher KJ, Pierson KS, Goodwin JS. Trends in androgen prescribing in the United States, 2001 to 2011. JAMA Intern Med 2013;173:1465-6.
9. Layton J B, Dongmei L, Meier CR, Sharpless J, Stürmer T, Jick SS, et al. Testosterone lab testing and initiation in the United Kingdom and the United States, 2000-2011. J Clin Endocrinol Metab 2014:jc20133570.