A little CFTR goes a long way: CFTR-dependent sweat secretion from G551D and R117H-5T cystic fibrosis subjects taking ivacaftor

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Char, Jessica E ^a   Wolfe, Marlene H ^a   Cho, Hyung Ju ^a   Park, Il Ho ^a   Jeong, Jin Hyeok ^a   Frisbee, Eric ^a   Dunn, Colleen ^b   Davies, Zoe ^b   Milla, Carlos ^b   Moss, Richard B ^b   Thomas, Ewart A C ^a   Wine, Jeffrey J ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; IVACAFTOR; PROTEIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG CONCENTRATION; DRUG EFFICACY; FEMALE; GENE DELETION; GENE MUTATION; GENOTYPE; HUMAN; IN VIVO STUDY; MALE; MULTICENTER STUDY (TOPIC); PATCH CLAMP TECHNIQUE; PROTEIN FUNCTION; SWEAT GLAND; SWEATING; WILD TYPE;

AMINO ACID SUBSTITUTION; AMINOPHENOLS; CASE-CONTROL STUDIES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FEMALE; HUMANS; MALE; QUINOLONES; SWEAT; SWEAT GLANDS;

EID: 84895543366     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088564     Document Type: Article

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