Lymphopenia-induced proliferation in Aire-deficient mice helps to explain their autoimmunity and differences from human patients

Frontiers in Immunology

Volumn 5, Issue FEB, 2014, Pages

  Kisand, Kai ^a   Peterson, Pärt ^a   Laan, Martti ^a  

^a UNIVERSITY OF TARTU   (Estonia)

Author keywords

AIRE; APECED; Autoantigens; Immune privilege; Lymphopenia induced proliferation; Negative selection; NOD; Thymus

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR7; HERMES ANTIGEN; INTERLEUKIN 21; INTERLEUKIN 5; INTERLEUKIN 7; INTERPHOTORECEPTOR RETINOID BINDING PROTEIN; L SELECTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; T LYMPHOCYTE RECEPTOR; TYROSINASE RELATED PROTEIN 1;

ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; APOPTOSIS; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CELL INFILTRATION; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; GENE MUTATION; HOMEOSTASIS; HUMAN; LYMPHOCYTOPENIA; NONHUMAN; PIGMENT EPITHELIUM; REGULATORY T LYMPHOCYTE; REVIEW; THYMOCYTE;

EID: 84895532029     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00051     Document Type: Review

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