Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels

Journal of Neuroscience

Volumn 34, Issue 10, 2014, Pages 3653-3667

  Riccio, Antonio ^a,b   Li, Yan ^c   Tsvetkov, Evgeny ^c,d   Gapon, Svetlana ^a   Yao, Gui Lan ^b   Smith, Kiersten S ^c   Engin, Elif ^c   Rudolph, Uwe ^c   Bolshakov, Vadim Y ^c   Clapham, David E ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MCLEAN HOSPITAL   (United States)

^d SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

Author keywords

Amygdala; Anxiety; Cholecystokinin 4; Fear; TRP channel; TRPC4

Indexed keywords

CHOLECYSTOKININ B RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; METABOTROPIC RECEPTOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL 4;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; CONDITIONING; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ELEVATED PLUS MAZE TEST; FEAR; GAIT; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; LONG TERM POTENTIATION; MOUSE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

AMYGDALA; ANXIETY; CHOLECYSTOKININ 4; FEAR; TRP CHANNEL; TRPC4;

AMYGDALA; ANIMALS; ANXIETY; DOWN-REGULATION; EVOKED POTENTIALS, SOMATOSENSORY; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; TRPC CATION CHANNELS;

EID: 84895453029     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2274-13.2014     Document Type: Article

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