Simplified clinical prediction scores to target viral load testing in adults with suspected first line treatment failure in Phnom Penh, Cambodia

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Van Griensven, Johan ^a,b   Phan, Vichet ^a   Thai, Sopheak ^a   Koole, Olivier ^b,c   Lynen, Lutgarde ^b  

^a Sihanouk Hospital Center of HOPE   (Cambodia)

^b INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; EFAVIRENZ; HEMOGLOBIN; LAMIVUDINE; NEVIRAPINE; STAVUDINE; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ADULT; AREA UNDER THE CURVE; ARTICLE; CAMBODIA; CD4 LYMPHOCYTE COUNT; CLINICAL PREDICTION SCORE; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HOSPITAL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PREDICTIVE VALUE; RECEIVER OPERATING CHARACTERISTIC; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; VALIDATION PROCESS; VIRUS LOAD; HIV INFECTIONS; PROGNOSIS; REPRODUCIBILITY; TREATMENT FAILURE; VIROLOGY;

ADULT; ANTI-HIV AGENTS; CAMBODIA; CD4 LYMPHOCYTE COUNT; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; MALE; PROGNOSIS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TREATMENT FAILURE; VIRAL LOAD;

EID: 84895184761     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087879     Document Type: Article

References (24)

1. World Health Organization (2011) GLOBAL HIV/AIDS RESPONSE: Epidemic update and health sector progress towards Universal Access: Progress report, November 2011. Geneva, Switzerland.
2. Lynen L, van Griensven J, Elliott J (2010) Monitoring for treatment failure in patients on first-line antiretroviral treatment in resource-constrained settings. Curr Opin HIV AIDS 5: 1-5.
3. World Health Organization (2013) Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Recommendations for a public health approach. Geneva, Switzerland.
4. Reid SD, Fidler SJ, Cooke GS (2013) Tracking the progress of HIV: the impact of point-of-care tests on antiretroviral therapy. Clin Epidemiol 5: 387-396.
5. Kumarasamy N, Krishnan S (2013) Beyond first-line HIV treatment regimens: the current state of antiretroviral regimens, viral load monitoring, and resistance testing in resource-limited settings. Curr Opin HIV AIDS 8: 586-590.
6. World Health Organization (2006) Antiretroviral therapy for HIV infection in adults and adolescents: Recommendations for a public health approach: 2006 Revision. Geneva, Switzerland.
7. Rutherford GW, Anglemyer AT, Easterbrook PJ, Horvath T, Vitoria M, et al. (2013) Predicting treatment failure in adults and children on antiretroviral therapy: systematic review of the performance characteristics of the 2010 World Health Organization criteria for virologic failure.
8. Lynen L, An S, Koole O, Thai S, Ros S, et al. (2009) An algorithm to optimize viral load testing in HIV-positive patients with suspected first-line antiretroviral therapy failure in Cambodia. J Acquir Immune Defic Syndr 52: 40-48.
9. Abouyannis M, Menten J, Kiragga A, Lynen L, Robertson G, et al. (2011) Development and validation of systems for rational use of viral load testing in adults receiving first-line ART in sub-Saharan Africa. AIDS 25: 1627-1635.
10. Phan V, Thai S, Koole O, Menten J, Meheus F, et al. (2013) Validation of a clinical prediction score to target viral load testing in adults with suspected first line treatment failure in resource-constrained settings. J Acquir Immune Defic Syndr.
11. Labhardt ND, Lejone T, Setoko M, Poka M, Ehmer J, et al. (2012) A clinical prediction score in addition to WHO criteria for anti-retroviral treatment failure in resource-limited settings-experience from Lesotho. PLoS One 7: e47937.
12. Colebunders R, Moses KR, Laurence J, Shihab HM, Semitala F, et al. (2006) A new model to monitor the virological efficacy of antiretroviral treatment in resource-poor countries. Lancet Infect Dis 6: 53-59. (Pubitemid 41831378)
13. Meya D, Spacek LA, Tibenderana H, John L, Namugga I, et al. (2009) Development and evaluation of a clinical algorithm to monitor patients on antiretrovirals in resource-limited settings using adherence, clinical and CD4 cell count criteria. J Int AIDS Soc 12: 3.
14. World Health Organization (2010) Antiretroviral therapy for HIV infection in adults and adolescents, Recommendations for a public health approach, 2010 Revision. Geneva, Switzerland.
15. Choun K, Thai S, Pe R, Lorent N, Lynen L, et al. (2013) Incidence and risk factors for tuberculosis in HIV-infected patients while on antiretroviral treatment in Cambodia. Trans R Soc Trop Med Hyg 107: 235-42.
16. Thai S, Koole O, Un P, Ros S, De MP, et al. (2009) Five-year experience with scaling-up access to antiretroviral treatment in an HIV care programme in Cambodia. Trop Med Int Health 14: 1048-1058.
17. van Griensven J, Thai S (2011) Predictors of immune recovery and the association with late mortality while on antiretroviral treatment in Cambodia. Trans R Soc Trop Med Hyg 105: 694-703.
18. Seymour DG, Green M, Vaz FG (1990) Making better decisions: construction of clinical scoring systems by the Spiegelhalter-Knill-Jones approach. BMJ 300: 223-226. (Pubitemid 20045526)
19. Spiegelhalter DJ (1985) Statistical methodology for evaluating gastrointestinal symptoms. Clin Gastroenterol 14: 489-515.
20. Berkley JA, Ross A, Mwangi I, Osier FH, Mohammed M, et al. (2003) Prognostic indicators of early and late death in children admitted to district hospital in Kenya: cohort study. BMJ 326: 361-366.
21. Gilks CF, Walker AS, Munderi P, Kityo C, Reid A, et al. (2013) A single CD4 test with 250 cells/mm3 threshold predicts viral suppression in HIV-infected adults failing first-line therapy by clinical criteria. PLoS One 8: e57580.
22. Sukapirom K, Onlamoon N, Thepthai C, Polsrila K, Tassaneetrithep B, et al. (2011) Performance evaluation of the Alere PIMA CD4 test for monitoring HIV-infected individuals in resource-constrained settings. J Acquir Immune Defic Syndr 58: 141-147.
23. Holmberg L, Vickers A (2013) Evaluation of prediction models for decision-making: beyond calibration and discrimination. PLoS Med 10: e1001491.
24. McGinn TG, Guyatt GH, Wyer PC, Naylor CD, Stiell IG, et al. (2000) Users' guides to the medical literature: XXII: how to use articles about clinical decision rules. Evidence-Based Medicine Working Group. JAMA 284: 79-84. (Pubitemid 30445665)