메뉴 건너뛰기




Volumn 39, Issue 2, 2014, Pages 225-232

1-Methyl-4-phenylpyridinium-induced cell death via autophagy through a Bcl-2/Beclin 1 complex-dependent pathway

Author keywords

Apoptosis; Autophagy; Bcl 2; Beclin 1; MPP+; mTOR; Oxidative stress

Indexed keywords

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BLOTTING, WESTERN; CELL DEATH; CELL LINE, TUMOR; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MEMBRANE PROTEINS; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SUBSTANTIA NIGRA; TOR SERINE-THREONINE KINASES;

EID: 84895088810     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-013-1208-8     Document Type: Article
Times cited : (32)

References (24)
  • 1
    • 0035120203 scopus 로고    scopus 로고
    • Further evidence for mitochondrial dysfunction in progressive supranuclear palsy
    • 1:CAS:528:DC%2BD3MXhtV2gu7Y%3D 11170735 10.1006/exnr.2000.7607
    • Albers DS, Swerdlow RH, Manfredi G, Gajewski C, Yang L, Parker WD Jr, Beal MF (2001) Further evidence for mitochondrial dysfunction in progressive supranuclear palsy. Exp Neurol 168(1):196-198
    • (2001) Exp Neurol , vol.168 , Issue.1 , pp. 196-198
    • Albers, D.S.1    Swerdlow, R.H.2    Manfredi, G.3    Gajewski, C.4    Yang, L.5    Parker Jr., W.D.6    Beal, M.F.7
  • 2
    • 0022478363 scopus 로고
    • + on endogenous dopamine release from the rat corpus striatum superfused in vitro
    • 1:CAS:528:DyaL28XitVSjs74%3D 3485463 10.1016/0006-8993(86)91050-4
    • + on endogenous dopamine release from the rat corpus striatum superfused in vitro. Brain Res 368(1):134-140
    • (1986) Brain Res , vol.368 , Issue.1 , pp. 134-140
    • Chang, G.D.1    Ramirez, V.D.2
  • 3
    • 0032904243 scopus 로고    scopus 로고
    • Apoptotic mechanisms in neurodegeneration: Possible relevance to glaucoma
    • 10230602
    • Tatton WG (1999) Apoptotic mechanisms in neurodegeneration: possible relevance to glaucoma. Eur J Ophthalmol 9(Suppl 1):S22-S29
    • (1999) Eur J Ophthalmol , vol.9 , Issue.SUPPL. 1
    • Tatton, W.G.1
  • 4
    • 34447118322 scopus 로고    scopus 로고
    • Melatonin protects SK-N-SH neuroblastoma cells from amphetamine-induced neurotoxicity
    • 1:CAS:528:DC%2BD2sXosFCjt7c%3D 17614837 10.1111/j.1600-079X.2007.00444.x
    • Klongpanichapak S, Phansuwan-Pujito P, Ebadi M, Govitrapong P (2007) Melatonin protects SK-N-SH neuroblastoma cells from amphetamine-induced neurotoxicity. J Pineal Res 43(1):65-73
    • (2007) J Pineal Res , vol.43 , Issue.1 , pp. 65-73
    • Klongpanichapak, S.1    Phansuwan-Pujito, P.2    Ebadi, M.3    Govitrapong, P.4
  • 5
    • 0036715414 scopus 로고    scopus 로고
    • Apoptotic molecules and MPTP-induced cell death
    • 1:CAS:528:DC%2BD38XmsVCit7w%3D 12200191 10.1016/S0892-0362(02)00213-1
    • Nicotra A, Parvez S (2002) Apoptotic molecules and MPTP-induced cell death. Neurotoxicol Teratol 24(5):599-605
    • (2002) Neurotoxicol Teratol , vol.24 , Issue.5 , pp. 599-605
    • Nicotra, A.1    Parvez, S.2
  • 6
    • 0037418614 scopus 로고    scopus 로고
    • Apoptotic mechanisms and antiapoptotic therapy in the MPTP model of Parkinson's disease
    • 1:CAS:528:DC%2BD3sXhvFeqsrc%3D 12628749 10.1016/S0378-4274(02)00428-9
    • Eberhardt O, Schulz JB (2003) Apoptotic mechanisms and antiapoptotic therapy in the MPTP model of Parkinson's disease. Toxicol Lett 139(2-3):135-151
    • (2003) Toxicol Lett , vol.139 , Issue.2-3 , pp. 135-151
    • Eberhardt, O.1    Schulz, J.B.2
  • 7
    • 59149091414 scopus 로고    scopus 로고
    • Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells
    • 1:CAS:528:DC%2BD1MXit1Gqurg%3D 19054297 10.1111/j.1600-079X.2008.00648.x
    • Kongsuphol P, Mukda S, Nopparat C, Villarroel A, Govitrapong P (2009) Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells. J Pineal Res 46(2):199-206
    • (2009) J Pineal Res , vol.46 , Issue.2 , pp. 199-206
    • Kongsuphol, P.1    Mukda, S.2    Nopparat, C.3    Villarroel, A.4    Govitrapong, P.5
  • 8
    • 34247186472 scopus 로고    scopus 로고
    • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    • 1:CAS:528:DC%2BD2sXjslOmtLs%3D 17347651 10.1038/sj.emboj.7601623
    • Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z (2007) Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J 26(7):1749-1760
    • (2007) EMBO J , vol.26 , Issue.7 , pp. 1749-1760
    • Scherz-Shouval, R.1    Shvets, E.2    Fass, E.3    Shorer, H.4    Gil, L.5    Elazar, Z.6
  • 9
    • 33847048316 scopus 로고    scopus 로고
    • Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
    • 1:CAS:528:DC%2BD2sXhsV2gtbc%3D 17200184 10.2353/ajpath.2007.060524
    • Zhu JH, Horbinski C, Guo F, Watkins S, Uchiyama Y, Chu CT (2007) Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death. Am J Pathol 170(1):75-86
    • (2007) Am J Pathol , vol.170 , Issue.1 , pp. 75-86
    • Zhu, J.H.1    Horbinski, C.2    Guo, F.3    Watkins, S.4    Uchiyama, Y.5    Chu, C.T.6
  • 10
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • 1:CAS:528:DC%2BD2sXhtlGmsrjP 18006683 10.1101/gad.1599207
    • Mizushima N (2007) Autophagy: process and function. Genes Dev 21(22):2861-2873
    • (2007) Genes Dev , vol.21 , Issue.22 , pp. 2861-2873
    • Mizushima, N.1
  • 11
    • 35448981935 scopus 로고    scopus 로고
    • Autophagy: From phenomenology to molecular understanding in less than a decade
    • 1:CAS:528:DC%2BD2sXhtF2qsL3I 17712358 10.1038/nrm2245
    • Klionsky DJ (2007) Autophagy: from phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol 8(11):931-937
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.11 , pp. 931-937
    • Klionsky, D.J.1
  • 12
    • 4344595626 scopus 로고    scopus 로고
    • Regulation and role of autophagy in mammalian cells
    • 1:CAS:528:DC%2BD2cXmvFemu7o%3D 15325584 10.1016/j.biocel.2004.02.002
    • Meijer AJ, Codogno P (2004) Regulation and role of autophagy in mammalian cells. Int J Biochem Cell Biol 36(12):2445-2462
    • (2004) Int J Biochem Cell Biol , vol.36 , Issue.12 , pp. 2445-2462
    • Meijer, A.J.1    Codogno, P.2
  • 13
    • 33747881231 scopus 로고    scopus 로고
    • Autophagy in neurodegenerative disease: Friend, foe or turncoat?
    • 1:CAS:528:DC%2BD28XptVGntLg%3D 16859759 10.1016/j.tins.2006.07.003
    • Nixon RA (2006) Autophagy in neurodegenerative disease: friend, foe or turncoat? Trends Neurosci 29(9):528-535
    • (2006) Trends Neurosci , vol.29 , Issue.9 , pp. 528-535
    • Nixon, R.A.1
  • 14
    • 33645512801 scopus 로고    scopus 로고
    • Bcl-2 inhibition of autophagy: A new route to cancer?
    • 1:CAS:528:DC%2BD28Xitlersrs%3D 16540632 10.1158/0008-5472.CAN-05-4412
    • Pattingre S, Levine B (2006) Bcl-2 inhibition of autophagy: a new route to cancer? Cancer Res 66(6):2885-2888
    • (2006) Cancer Res , vol.66 , Issue.6 , pp. 2885-2888
    • Pattingre, S.1    Levine, B.2
  • 15
    • 20344406240 scopus 로고    scopus 로고
    • Autophagy in metazoans: Cell survival in the land of plenty
    • 1:CAS:528:DC%2BD2MXks1Gmtb0%3D 15928708 10.1038/nrm1660
    • Lum JJ, DeBerardinis RJ, Thompson CB (2005) Autophagy in metazoans: cell survival in the land of plenty. Nat Rev Mol Cell Biol 6(6):439-448
    • (2005) Nat Rev Mol Cell Biol , vol.6 , Issue.6 , pp. 439-448
    • Lum, J.J.1    Deberardinis, R.J.2    Thompson, C.B.3
  • 16
    • 35848947235 scopus 로고    scopus 로고
    • Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: Implications for neurodegeneration and cell death
    • 1:CAS:528:DC%2BD2sXhtlOhsL%2FK 2779565 17622797
    • Chu CT, Zhu J, Dagda R (2007) Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death. Autophagy 3(6):663-666
    • (2007) Autophagy , vol.3 , Issue.6 , pp. 663-666
    • Chu, C.T.1    Zhu, J.2    Dagda, R.3
  • 18
    • 0035032723 scopus 로고    scopus 로고
    • Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
    • 1:CAS:528:DC%2BD3MXks1Cqtbc%3D 1083858 11306555 10.1093/embo-reports/ kve061
    • Kihara A, Kabeya Y, Ohsumi Y, Yoshimori T (2001) Beclin- phosphatidylinositol 3-kinase complex functions at the trans-Golgi network. EMBO Rep 2(4):330-335
    • (2001) EMBO Rep , vol.2 , Issue.4 , pp. 330-335
    • Kihara, A.1    Kabeya, Y.2    Ohsumi, Y.3    Yoshimori, T.4
  • 19
    • 10344262564 scopus 로고    scopus 로고
    • Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
    • 1:CAS:528:DC%2BD2cXhtVarsL%2FJ 15558033 10.1038/ncb1192
    • Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, Thompson CB, Tsujimoto Y (2004) Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 6(12):1221-1228
    • (2004) Nat Cell Biol , vol.6 , Issue.12 , pp. 1221-1228
    • Shimizu, S.1    Kanaseki, T.2    Mizushima, N.3    Mizuta, T.4    Arakawa-Kobayashi, S.5    Thompson, C.B.6    Tsujimoto, Y.7
  • 20
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • 1:CAS:528:DC%2BD3cXovFaiurk%3D 11060023 10.1093/emboj/19.21.5720
    • Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E, Ohsumi Y, Yoshimori T (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19(21):5720-5728
    • (2000) EMBO J , vol.19 , Issue.21 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3    Yamamoto, A.4    Kirisako, T.5    Noda, T.6    Kominami, E.7    Ohsumi, Y.8    Yoshimori, T.9
  • 21
    • 64549084052 scopus 로고    scopus 로고
    • Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death
    • 1:CAS:528:DC%2BD1MXkslymt78%3D 19318089 10.1016/j.bbrc.2009.03.095
    • Park KJ, Lee SH, Lee CH, Jang JY, Chung J, Kwon MH, Kim YS (2009) Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death. Biochem Biophys Res Commun 382(4):726-729
    • (2009) Biochem Biophys Res Commun , vol.382 , Issue.4 , pp. 726-729
    • Park, K.J.1    Lee, S.H.2    Lee, C.H.3    Jang, J.Y.4    Chung, J.5    Kwon, M.H.6    Kim, Y.S.7
  • 22
    • 53549089861 scopus 로고    scopus 로고
    • Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation
    • 1:CAS:528:DC%2BD1cXht12rurnM 2677707 18769111
    • Wei Y, Sinha S, Levine B (2008) Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation. Autophagy 4(7):949-951
    • (2008) Autophagy , vol.4 , Issue.7 , pp. 949-951
    • Wei, Y.1    Sinha, S.2    Levine, B.3
  • 23
    • 34548834983 scopus 로고    scopus 로고
    • Autophagy and clearence of apoptotic cells
    • 10.1051/medsci/20072389696
    • Pattingre S, Codogno P (2007) Autophagy and clearence of apoptotic cells. Med Sci (Paris) 23(8-9):696-698
    • (2007) Med Sci (Paris) , vol.23 , Issue.8-9 , pp. 696-698
    • Pattingre, S.1    Codogno, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.