An estimate of the prevalence of epilepsy in Sub-Saharan Africa: A systematic analysis

Journal of Global Health

Volumn 2, Issue 2, 2012, Pages

  Paul, Abigail ^a   Adeloye, Davies ^a   George Carey, Rhiannon ^a   Kolčić, Ivana ^b   Grant, Liz ^a   Chan, Kit Yee ^c,d  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF SPLIT   (Croatia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84895076558     PISSN: 20472978     EISSN: 20472986     Source Type: Journal    
DOI: 10.7189/jogh.02.020405     Document Type: Article

References (75)

1. World Health Organization. UN High-level Meeting on NCDs: Summary report of the discussions at the round tables. Geneva: WHO, 2011. Available at:http://www.who.int/nmh/events/moscow_ncds_2011/round_tables_ summary.pdf. Accessed: 8 February 2012
2. United Nations. Prevention and control of non-communicable diseases: Report of the Secretary-General-A/66/83. New York: UN, 2011. Available at: http://www.un.org/ga/search/view_doc.asp?symbol=A/66/83&referer=/ english/&Lang=E. Accessed: 08 February 2012
3. Alwan A, MacLean DR, Riley LM, d'Espaignet ET, Mathers CD, Stevens GA, et al. Monitoring and surveillance of chronic non-communicable diseases: progress and capacity in high-burden countries. Lancet. 2010;376:1861-8 Medline:21074258 doi:10.1016/S0140-6736(10)61853-3
4. Beaglehole R, Bonita R, Horton R, Adams C, Alleyne G, Asaria P, et al. Priority actions for the non-communicable disease crisis. Lancet. 2011;377:1438-47. Medline:21474174 doi:10.1016/S0140-6736(11)60393-0
5. Chan KY. A health policy and systems approach to addressing the growing burden of noncommunicable diseases in China. J Glob Health. 2011;1:28-31
6. World Health Organization. The Global burden of diseases, injuries and risk factors study: Operations manual. Geneva: WHO, 2009
7. Newton CR, Garcia HH. Epilepsy in poor regions of the world. Lancet. 2012;380:1193-201. Medline:23021288 doi:10.1016/S0140-6736(12)61381-6
8. Birbeck G, Chomba E, Atadzhanov M, Mbewe E, Haworth A. The social and economic impact of epilepsy in Zambia: a cross-sectional study. Lancet Neurol. 2007;6:39-44. Medline:17166800 doi:10.1016/S1474-4422(06)70629-9
9. Baingana FK, Bos ER. Changing patterns of disease and mortality in Sub-Saharan Africa: An Overview. IN: Disease and Mortality in Sub-Saharan Africa. Washington DC: The World Bank, 2006. Available at: http://www. dcp2.org/file/66/Disease%20and%20Mortality%20in%20SSA.pdf. Accessed: 24 April 2012
10. Baskind R, Birbeck GL. Epilepsy-associated stigma in Sub-Saharan Africa: The social landscape of a disease. Epilepsy Behav. 2005;7:68-73. Medline:15978874 doi:10.1016/j.yebeh.2005.04.009
11. Viteva E. Impact of stigma on the quality of life of patients with refractory epilepsy. Seizure. 2012; pii:S1059-1311(12)00285-3. Medline:23137970
12. Nubukpo P, Preux PM, Houinato D, Radji A, Grunitzky EK, Avodé G, et al. Psychosocial issues in people with epilepsy in Togo and Benin (West Africa) I. Anxiety and depression measured using Goldberg's scale. Epilepsy Behav. 2004;5:722-7. Medline:15380125 doi:10.1016/j.yebeh.2004.07.001
13. Osungbade KO, Siyanbade SL. Myths, misconceptions, and misunderstandings about epilepsy in a Nigerian rural community: implications for community health interventions. Epilepsy Behav. 2011;21:425-9. Medline: 21705278 doi:10.1016/j.yebeh.2011.05.014
14. International League Against Epilepsy. Epilepsy defined. The ILAE newsletter 2006;2:1-8
15. Preux PM, Druet-Cabanac M. Epidemiology and aetiology of epilepsy in Sub-Saharan Africa. Lancet Neurol. 2005;4:21-31. Medline:15620854 doi:10.1016/S1474-4422(04)00963-9
16. Quet F, Guerchet M, Pion SD, Ngoungou EB, Nicoletti A, Preux PM. Meta-analysis of the association between cysticercosis and epilepsy in Africa. Epilepsia. 2010;51:830-7. Medline:19919664 doi:10.1111/j.1528-1167.2009.02401.x
17. Kanobana K, Praet N, Kabwe C, Dorny P, Lukanu P, Madinga J, et al. High prevalence of Taeniasolium cysticercosis in a village community of Bas-Congo, Democratic Republic of Congo. Int J Parasitol. 2011;41:1015-8. Medline:21763695 doi:10.1016/j.ijpara.2011.06.004
18. Kaiser C, Kipp W, Asaba G, Mugisa C, Kabagambe G, Rating D, et al. The prevalence of epilepsy follows the distribution of onchocerciasis in a West Ugandan focus. Bull World Health Organ. 1996;74:361-7. Medline: 8823957
19. World Health Organization. WHO global malaria report: World malaria report 2010. Geneva: WHO, 2010
20. Idro R, Ndiritu M, Ogutu B, Mithwani S, Berkley J, Crawley J, et al. Burden, features, and outcome of neurological involvement in acute falciparum malaria in Kenyan children. JAMA. 2007;297:2232-40. Medline: 17519413 doi:10.1001/jama.297.20.2232
21. Pearson L, Larsson M, Fauveau V, Standley J. Childbirth care. In: World Health Organization: Opportunities for Africa's newborns: Practical data, policy and programmatic support for newborn care in Africa. Geneva: WHO, 2007
22. Burton KJ, Rogathe J, Whittaker R, Mankad K, Hunter E, Burton MJ, et al. Epilepsy in Tanzanian children: Association with perinatal events and other risk factors. Epilepsia. 2012;53:752-60. Medline:22308971 doi:10.1111/j.1528-1167.2011.03395.x
23. Mung'ala-Odera V, White S, Meehan R, Otieno GO, Njuguna P, Mturi N, et al. Prevalence, incidence and risk factors of epilepsy in older children in rural Kenya. Seizure. 2008;17:396-404. Medline:18249012 doi:10.1016/j. seizure.2007.11.028
24. Edwards T, Scott AG, Munyoki G, Mung'ala-Odera V, Chengo E, Bauni E, et al. Active convulsive epilepsy in a rural district of Kenya: a study of prevalence and possible risk factors. Lancet Neurol. 2008;7:50-6. Medline: 18068520 doi:10.1016/S1474-4422(07)70292-2
25. International League Against Epilepsy. Guidelines for epidemiologic studies on epilepsy: Commission on epidemiology and prognosis. Epilepsia. 1993;34:592-6. Medline:8330566 doi:10.1111/j.1528-1157.1993. tb00433.x
26. Annegers JF, Hauser WA, Coan SP, Rocca WA. A Population-Based Study of Seizures after Traumatic Brain Injuries. N Engl J Med. 1998;338:20-4. Medline:9414327 doi:10.1056/NEJM199801013380104
27. Diop AG, de Boer HM, Mandlhate C, Prilipko L, Meinardi H. The global campaign against epilepsy in Africa. Acta Trop. 2003;87:149-59. Medline:12781390 doi:10.1016/S0001-706X(03)00038-X
28. Njamanshi AK, Sini V, Djientcheu VP, Ongolo-Zogo P, Mapoure Y, Yepnjio FN, et al. Risk factors associated with epilepsy in a rural area in Cameroon: A preliminary study. Afr J Neurol Sci. 2007;26:18-26
29. Kullmann DM. Genetics of epilepsy. J Neurol Neurosurg Psychiatry. 2002;73:II32-5. Medline:12536158 doi:10.1136/jnnp.73.suppl_2.ii32
30. Yemadje LP, Houinato D, Quet F, Druet-Cabanac M, Preux PM. Understanding the differences in prevalence of epilepsy in tropical regions. Epilepsia. 2011;52:1376-81. Medline:21627649 doi:10.1111/j.1528-1167.2011.03099.x
31. Yemadje LP, Houinato D, Boumediene F, Ngoungou EB, Preux PM, et al. Prevalence of epilepsy in the 15 years and older in Benin: A door-to-door nationwide survey. Epilepsy Res. 2012;99:318-26. Medline:22281063 doi:10.1016/j.eplepsyres.2011.12.012
32. Ngoungou EB, Quet F, Minso M, Assengone-Zeh Y, Houinato D, Druet-Cabanac M, et al. First populationbased survey of epilepsy in Gabon, Central Africa. Neuroepidemiology. 2009;33:68-78
33. Balogou AAK, Grunitzky EK, Belo M, Sankaredja M, Djagba DD, Tatagan-Agbi K, et al. Management of epilepsy patients in Batamaribadistricy, Togo. Acta Neurol Scand. 2007;116:211-6. Medline:17824896 doi:10.1111/ j.1600-0404.2007.00871.x
34. Avode DG, Bouteille B, Houngbe F, Adjien C, Adjide C, Houinato D, Druet-Cabanac M. Epilepsy, cysticercosis and neurocysticercosis in Benin. Eur Neurol. 1998;39:60-1. Medline:9476727
35. Ngugi AK, Bottomley C, Kleinschmidt I, Sander JW, Newton CR. Estimation of the burden of active and life-time epilepsy: A meta-analytic approach. Epilepsia. 2010;51:883-90. Medline:20067507 doi:10.1111/j.1528-1167.2009.02481.x
36. United Nations Statistics Division. Composition of macro geographical (continental) regions, geographical subregions, and selected economic and other groupings. New York: UN, 2011. Available at:http://unstats.un.org/ unsd/methods/m49/m49regin.htm. Accessed: 16 March 2012
37. Prischich F, De Rinaldis M, Bruno F, Egeo G, Santori C, Zappaterreno A, et al. High prevalence of epilepsy in a village in the Littoral Province of Cameroon. Epilepsy Res. 2008;82:200-10. Medline:18976884 doi:10.1016/j. eplepsyres.2008.09.004
38. Osuntokun BO, Adeuja AOG, Nottidge VA, Bademosi O, Olumide A, Ige O, et al. Prevalence of the Epilepsies in Nigerian Africans: A community-Based Study. Epilepsia. 1987;28:272-9. Medline:3582291 doi:10.1111/j.1528-1157.1987.tb04218.x
39. Simms V, Atijosan O, Kuper H, Nuhu A, Rischewski D, Lavy C. Prevalence of epilepsy in Rwanda: a national crosssectional survey. Trop Med Int Health. 2008;13:1047-53. Medline:18564351 doi:10.1111/j.1365-3156.2008.02108.x
40. Duggan MB. Epilepsy in rural Ugandan children: seizure pattern, age of onset and associated findings. Afr Health Sci. 2010;10:218-25. Medline:21327131
41. Pan African Association of Neurological Sciences (PAANS). Congress Report. In: 14th Congress Pan African Association of Neurological Sciences, May 21-24, 2000, Blantyre, Malawi. Available at: http://ajns.paans.org/ article.php3?id_article=179. Accessed: 28 April 2012
42. Placencia M, Shorvan SD, Paredes V, Sander JW, Suarez J, Cascante SM. Epileptic seizures in an Andean region of Ecuador: incidence and prevalence and regional variation. Brain. 1992;115:771-82. Medline:1628201 doi:10.1093/brain/115.3.771
43. Durkin MS, Davidson LL, Desai P, Hasan ZM, Khan N, Thorburn MJ, et al. Validity of the ten questions screened for childhood disability: Results from population-based studies in Bangladesh, Jamaica and Pakistan. Epidemiology. 1994;5:283-9. Medline:7518697 doi:10.1097/00001648-199405000-00005
44. Ndoye NF, Sow AD, Diop AG, Sessouma B, Sene-Diouf F, Boissy L, et al. Prevalence of epilepsy its treatment gap and knowledge, attitude and practice of its population in sub-urban Senegal an ILAE/IBE/WHO study. Seizure. 2005;14:106-11. Medline:15694563 doi:10.1016/j.seizure.2004.11.003
45. Wang IJ, Chu SY, Wang CY, Wang PJ, Hwu WL. Maple syrup urine disease presenting with neonatal status epilepticus: report of one case. Acta Paediatr Taiwan. 2003;44:246-8. Medline:14674232
46. Tekle-Haimanot R, Forsgren L, Abebe M, Gebre-Mariam A, Heijbel J, Holmgren G, et al. Clinical and electroencephalographic characteristics of epilepsy in rural Ethiopia: a community-based study. Epilepsy Res. 1990;7:230-9. Medline:2289482 doi:10.1016/0920-1211(90)90020-V
47. Andriantseheno LM, Ralaizandriny D. Community prevalence of epilepsy in the Malagasy. Epilepsia. 2004;16:83-6
48. Christianson AL, Zwane ME, Manga P, Rosen E, Venter A, Kromberg JG. Epilepsy in rural South African children-prevalence, associated disability and management. S Afr Med J. 2000;90:262-6. Medline:10853404
49. Coleman R, Loppy L, Walraven G. The treatment gap and primary health care for people with epilepsy in rural Gambia. Bull World Health Organ. 2002;80:378-83. Medline:12077613
50. Debrock C, Preux PC, Houinato D, Druet-Cabanac M, Kassa F, Adjien C, et al. Estimation of the prevalence of epilepsy in the Benin region of Zinvie using the capture-recapture method. Int J Epidemiol. 2000;29:330-5. Medline:10817133 doi:10.1093/ije/29.2.330
51. Pan African Association of Neurological Sciences (PAANS). Congress Report. In: 12th Congress Pan African Association of Neurological Sciences, May 18-23, 1996, Durban, South Africa. Available at: http://ajns.paans. org/article.php3?id_articlr=179. Accessed: 28 April 2012
52. Dent W, Helbok R, Matuja WBP, Scheunemann S, Schmutzhard E. Prevalence of active epilepsy in a rural area in South Tanzania: A door-to-door survey. Epilepsia. 2005;46:1963-9. Medline:16393163 doi:10.1111/j.1528-1167.2005.00338.x
53. Longe AC, Osuntokun BO. Prevalence of neurological disorders in Udo, a rural community on southern Nigeria. Trop Geogr Med. 1989;41:36-40. Medline:2763344
54. Rwiza HT, Kilonzo GP, Haule J, Matuja WBP, Mteza I, Mbena P, et al. Prevalence and incidence of epilepsy in Ulanga, a rural Tanzanian district: A community-based study. Epilepsia. 1992;33:1051-6. Medline:1464263 doi:10.1111/j.1528-1157.1992.tb01758.x
55. Winkler AS, Kerschbaumsteiner K, Stelzhammer B, Meindl M, Kaaya J, Schumtzhard E. Prevalence, incidence and clinical characteristics of epilepsy-A community-based door-to-door study in northern Tanzania. Epilepsia. 2009;50:2310-3. Medline:19583783 doi:10.1111/j.1528-1167.2009.02184.x
56. Dozie INS, Onwuliri COE, Nwoke BEB, Chukwuocha UM, Chikwendu CI, Okoro I, et al. Onchocerciasis and epilepsy in parts of the Imo river basin, Nigeria: A preliminary report. Public Health. 2006;120:448-50. Medline: 16524608 doi:10.1016/j.puhe.2005.10.010
57. Shorvon SD, Farmer PJ. Epilepsy in developing countries: a review of epidemiological, sociocultural, and treatment aspects. Epilepsia. 1988;29:S36-54. Medline:3292235 doi:10.1111/j.1528-1157.1988.tb05790.x
58. Dumas M, Gunitzky E, Deniau M, Dabis F, Bouteille B, Belo M, et al. Epidemiological study of neuro-cysticercosis in northern Togo (West Africa). Acta Leiden. 1989;57:191-6. Medline:2488997
59. Kaamugisha J, Feksi AT. Determining the prevalence of epilepsy in the semi-urban population of Nakuru, Kenya, comparing two independent methods not apparently used before in epilepsy studies. Neuroepidemiology 1988;7:115-21. Medline:3136404 doi:10.1159/000110144
60. Kabore JK, Cabore TW, Melaku Z, Druet-Cabanac M. Epilepsy in a focus of onchocerciasis in Burkina Faso. Lancet. 1996;347:836. Medline:8622372 doi:10.1016/S0140-6736(96)90917-4
61. Almu S, Tadesse Z, Cooper P, Hackett R. The prevalence of epilepsy in the Zay Society, Ethiopia-An area of high prevalence. Seizure. 2006;15:211-3. Medline:16488161 doi:10.1016/j.seizure.2006.01.004
62. Goudsmit J, van der Waals FW, Gajdusek DC. Epilepsy in the Gbawein and Wroughbarh Clan of the Grand Bassa County, Liberia: the endemic occurrence of 'see-ee' in the native population. Neuroepidemiology. 1983;2:24-34. doi:10.1159/000110507
63. Nitiéma P, Carabin H, Hounton S, Praet N, Cowan LD, Ganaba R, et al. Prevalence case-control study of epilepsy in three Burkina Faso villages. Acta Neurol Scand. 2012;126:270-8. Medline:22289127 doi:10.1111/j.1600-0404.2011.01639.x
64. Atijosan O, Kuper H, Rischewski D, Simms V, Lavy C. Musculoskeletal impairment survey in Rwanda: design of survey tool, survey methodology, and results of the pilot study (a cross sectional survey). BMC Musculoskelet Disord. 2007;8:30. Medline:17391509 doi:10.1186/1471-2474-8-30
65. Banerjee PN, Hauser WA. Incidence and Prevalence.IN: Epilepsy: A Comprehensive Textbook, Volume 1. Philadelphia: Lippincott Williams and Wilkins, 2008
66. Mac TL, Tran DS, Quet F, Odermatt P, Preux PM, Tan CT. Epidemiology, aetiology, and clinical management of epilepsy in Asia: a systematic review. Lancet Neurol. 2007;6:533-43. Medline:17509488 doi:10.1016/S1474-4422(07)70127-8
67. Bharucha NE. Epidemiology. In: World Health Organization. Atlas: Epilepsy care in the world 2005. Geneva: WHO, 2005
68. Hotez PJ, Kamath A. Neglected tropical diseases in Sub-Saharan Africa: review of their prevalence, distribution, and disease burden. PLoS Negl Trop Dis. 2009;3:e412. Medline:19707588 doi:10.1371/journal. pntd.0000412
69. Sander JWAS, Shorvon SD. Incidence and prevalence studies in epilepsy and their methodological problems: a review. J Neurol Neurosurg Psychiatry. 1987;50:829-39. Medline:3305790 doi:10.1136/jnnp.50.7.829
70. Jilek-Aall L, Jilek M, Kaaya J, Mkombachepa L, Hillary K. Psychological studies of epilepsy in Africa. Soc Sci Med. 1997;45:783-95. Medline:9226801 doi:10.1016/S0277-9536(96)00414-5
71. Rwiza HT, Matuja WBP, Kilonzo GP, Haule J, Mbena P, Mwang'ombola R, et al. Knowledge, attitude, and practice toward epilepsy among rural Tanzanian residents. Epilepsia. 1993;34:1017-23. Medline:8243350 doi:10.1111/j.1528-1157.1993.tb02127.x
72. Foster G. The capacity of the extended family safety net for orphans in Africa. Psychol Health Med. 2000;5:55-62 doi:10.1080/135485000106007
73. ILAE/IBE/WHO. Global campaign against epilepsy: Out of the Shadows. Heemstede: International Bureau for Epilepsy, 2003. Available at: http://www.who.int/mental_health/management/en/GcaeBroEn.pdf. Accessed: 26 April 2012
74. World Health Organization. Epilepsy in the WHO African region: Bridging the gap. Brazzaville: WHO, 2004
75. Kenya Association for the Welfare of People with Epilepsy. Public education and awareness creation. Nairobi: KAWE, 2008. Available at: http://www.kawe-kenya.org/SubProgrammes.php?id=19. Accessed: 26 April 2012