메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages 62-67

Pilot clinical trial on the efficacy of prophylactic use of vitamin K 1-based cream (Vigorskin) to prevent cetuximab-induced skin rash in patients with metastatic colorectal cancer

Author keywords

Acneiform rash; Cetuximab plus chemotherapy; Phytomenadione; Prevention; Topical treatment

Indexed keywords

ACNEIFORM RASH; CETUXIMAB PLUS CHEMOTHERAPY; PHYTOMENADIONE; PREVENTION; TOPICAL TREATMENT;

EID: 84895074194     PISSN: 15330028     EISSN: 19380674     Source Type: Journal    
DOI: 10.1016/j.clcc.2013.10.001     Document Type: Article
Times cited : (37)

References (39)
  • 1
    • 73249130298 scopus 로고    scopus 로고
    • Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: The CELIM randomised phase 2 trial
    • G. Folprecht, T. Gruenberger, and W.O. Bechstein et al. Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial Lancet Oncol 11 2004 38 47
    • (2004) Lancet Oncol , vol.11 , pp. 38-47
    • Folprecht, G.1    Gruenberger, T.2    Bechstein, W.O.3
  • 2
    • 2142641698 scopus 로고    scopus 로고
    • Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
    • L.B. Saltz, N.J. Meropol, and P.J. Loehrer et al. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor J Clin Oncol 22 2004 1201 1208
    • (2004) J Clin Oncol , vol.22 , pp. 1201-1208
    • Saltz, L.B.1    Meropol, N.J.2    Loehrer, P.J.3
  • 3
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • D. Cunningham, Y. Humblet, and S. Siena et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer N Engl J Med 351 2004 337 345
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 4
    • 36148941301 scopus 로고    scopus 로고
    • Cetuximab for the treatment of colorectal cancer
    • D.J. Jonker, C.J. O'Callaghan, and C.S. Karapetis et al. Cetuximab for the treatment of colorectal cancer N Engl J Med 357 2007 2040 2048
    • (2007) N Engl J Med , vol.357 , pp. 2040-2048
    • Jonker, D.J.1    O'Callaghan, C.J.2    Karapetis, C.S.3
  • 5
    • 44249111440 scopus 로고    scopus 로고
    • EPIC: Phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer
    • A.F. Sobrero, J. Maurel, and L. Fehrenbacher et al. EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer J Clin Oncol 26 2008 2311 2319
    • (2008) J Clin Oncol , vol.26 , pp. 2311-2319
    • Sobrero, A.F.1    Maurel, J.2    Fehrenbacher, L.3
  • 6
    • 33750615769 scopus 로고    scopus 로고
    • Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines
    • H.J. Lenz, E. Van Cutsem, and S. Khambata-Ford et al. Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines J Clin Oncol 24 2006 4914 4921
    • (2006) J Clin Oncol , vol.24 , pp. 4914-4921
    • Lenz, H.J.1    Van Cutsem, E.2    Khambata-Ford, S.3
  • 7
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • E. Van Cutsem, C.H. Kohne, and E. Hitre et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer N Engl J Med 360 2009 1408 1417
    • (2009) N Engl J Med , vol.360 , pp. 1408-1417
    • Van Cutsem, E.1    Kohne, C.H.2    Hitre, E.3
  • 8
    • 79956310674 scopus 로고    scopus 로고
    • Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: The OPUS study
    • C. Bokemeyer, I. Bondarenko, and J.T. Hartmann et al. Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study Ann Oncol 22 2011 1535 1546
    • (2011) Ann Oncol , vol.22 , pp. 1535-1546
    • Bokemeyer, C.1    Bondarenko, I.2    Hartmann, J.T.3
  • 9
    • 79959337678 scopus 로고    scopus 로고
    • Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: Results of the randomised phase 3 MRC COIN trial
    • T.S. Maughan, R.A. Adams, and C.G. Smith et al. Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial Lancet 377 2011 2103 2114
    • (2011) Lancet , vol.377 , pp. 2103-2114
    • Maughan, T.S.1    Adams, R.A.2    Smith, C.G.3
  • 10
    • 38549088386 scopus 로고    scopus 로고
    • Dermatologic toxicities associated with EGFR inhibitors: The clinical psychologist's perspective. Impact on health-related quality of life and implications for clinical management of psychological sequelae
    • L.I. Wagner, and M.E. Lacouture Dermatologic toxicities associated with EGFR inhibitors: the clinical psychologist's perspective. Impact on health-related quality of life and implications for clinical management of psychological sequelae Oncology (Williston Park) 21 2007 34 36
    • (2007) Oncology (Williston Park) , vol.21 , pp. 34-36
    • Wagner, L.I.1    Lacouture, M.E.2
  • 11
    • 67349083594 scopus 로고    scopus 로고
    • Skin toxicities associated with epidermal growth factor receptor inhibitors
    • T. Li, and R. Perez-Soler Skin toxicities associated with epidermal growth factor receptor inhibitors Target Oncol 4 2009 107 119
    • (2009) Target Oncol , vol.4 , pp. 107-119
    • Li, T.1    Perez-Soler, R.2
  • 12
    • 77949270340 scopus 로고    scopus 로고
    • Psychological effects of cetuximab-induced cutaneous rash in advanced colorectal cancer patients
    • F. Romito, F. Giuliani, and C. Cormio et al. Psychological effects of cetuximab-induced cutaneous rash in advanced colorectal cancer patients Support Care Cancer 18 2010 329 334
    • (2010) Support Care Cancer , vol.18 , pp. 329-334
    • Romito, F.1    Giuliani, F.2    Cormio, C.3
  • 13
    • 77956802819 scopus 로고    scopus 로고
    • Effects of epidermal growth factor receptor inhibitor-induced dermatologic toxicities on quality of life
    • S.S. Joshi, S. Ortiz, and J.N. Witherspoon et al. Effects of epidermal growth factor receptor inhibitor-induced dermatologic toxicities on quality of life Cancer 116 2010 3916 3923
    • (2010) Cancer , vol.116 , pp. 3916-3923
    • Joshi, S.S.1    Ortiz, S.2    Witherspoon, J.N.3
  • 14
    • 84872115684 scopus 로고    scopus 로고
    • Quality of life analysis in patients with KRAS wild-type metastatic colorectal cancer treated first-line with cetuximab plus irinotecan, fluorouracil and leucovorin
    • I. Lang, C.H. Kohne, and G. Folprecht et al. Quality of life analysis in patients with KRAS wild-type metastatic colorectal cancer treated first-line with cetuximab plus irinotecan, fluorouracil and leucovorin Eur J Cancer 49 2012 439 448
    • (2012) Eur J Cancer , vol.49 , pp. 439-448
    • Lang, I.1    Kohne, C.H.2    Folprecht, G.3
  • 15
    • 33748935930 scopus 로고    scopus 로고
    • Dermatologic side effects associated with the epidermal growth factor receptor inhibitors
    • A.L. Agero, S.W. Dusza, and C. Benvenuto-Andrade et al. Dermatologic side effects associated with the epidermal growth factor receptor inhibitors J Am Acad Dermatol 55 2006 657 670
    • (2006) J Am Acad Dermatol , vol.55 , pp. 657-670
    • Agero, A.L.1    Dusza, S.W.2    Benvenuto-Andrade, C.3
  • 16
    • 67650695000 scopus 로고    scopus 로고
    • Clinical predictors of severe cetuximab-induced rash: Observations from 933 patients enrolled in North Central Cancer Treatment Group study N0147
    • A. Jatoi, E.M. Green, and K.M. Rowland et al. Clinical predictors of severe cetuximab-induced rash: observations from 933 patients enrolled in North Central Cancer Treatment Group study N0147 Oncology 77 2009 120 123
    • (2009) Oncology , vol.77 , pp. 120-123
    • Jatoi, A.1    Green, E.M.2    Rowland, K.M.3
  • 17
    • 67650702948 scopus 로고    scopus 로고
    • Risk of high-grade skin rash in cancer patients treated with cetuximab - An antibody against epidermal growth factor receptor: Systemic review and meta-analysis
    • X. Su, M.E. Lacouture, and Y. Jia et al. Risk of high-grade skin rash in cancer patients treated with cetuximab - an antibody against epidermal growth factor receptor: systemic review and meta-analysis Oncology 77 2009 124 133
    • (2009) Oncology , vol.77 , pp. 124-133
    • Su, X.1    Lacouture, M.E.2    Jia, Y.3
  • 18
    • 67449107894 scopus 로고    scopus 로고
    • Correlation between efficacy and skin rash occurrence following treatment with the epidermal growth factor receptor inhibitor cetuximab: A single institution retrospective analysis
    • M. Orditura, F. De Vita, and G. Galizia et al. Correlation between efficacy and skin rash occurrence following treatment with the epidermal growth factor receptor inhibitor cetuximab: a single institution retrospective analysis Oncol Rep 21 2009 1023 1028
    • (2009) Oncol Rep , vol.21 , pp. 1023-1028
    • Orditura, M.1    De Vita, F.2    Galizia, G.3
  • 19
    • 84865092896 scopus 로고    scopus 로고
    • Intrapatient cetuximab dose escalation in metastatic colorectal cancer according to the grade of early skin reaction: The randomized EVEREST study
    • E. Van Cutsem, D. Teipar, and D. Vanbeckevoort et al. Intrapatient cetuximab dose escalation in metastatic colorectal cancer according to the grade of early skin reaction: the randomized EVEREST study J Clin Oncol 30 2012 2861 2868
    • (2012) J Clin Oncol , vol.30 , pp. 2861-2868
    • Van Cutsem, E.1    Teipar, D.2    Vanbeckevoort, D.3
  • 20
    • 79952601240 scopus 로고    scopus 로고
    • Management of skin toxicity associated with cetuximab treatment in combination with chemotherapy or radiotherapy
    • C. Pinto, C.A. Barone, and G. Girolomoni et al. Management of skin toxicity associated with cetuximab treatment in combination with chemotherapy or radiotherapy Oncologist 16 2011 228 238
    • (2011) Oncologist , vol.16 , pp. 228-238
    • Pinto, C.1    Barone, C.A.2    Girolomoni, G.3
  • 21
    • 79958043820 scopus 로고    scopus 로고
    • Cetuximab in the treatment of patients with colorectal cancer
    • C.R. Garrett, and C. Eng Cetuximab in the treatment of patients with colorectal cancer Expert Opin Biol Ther 11 2011 937 949
    • (2011) Expert Opin Biol Ther , vol.11 , pp. 937-949
    • Garrett, C.R.1    Eng, C.2
  • 22
    • 36849093857 scopus 로고    scopus 로고
    • Randomized double-blind trial of prophylactic oral minocycline and topical tazarotene for cetuximab-associated acne-like eruption
    • A. Scope, A.L. Agero, and S.W. Dusza et al. Randomized double-blind trial of prophylactic oral minocycline and topical tazarotene for cetuximab-associated acne-like eruption J Clin Oncol 25 2007 5390 5396
    • (2007) J Clin Oncol , vol.25 , pp. 5390-5396
    • Scope, A.1    Agero, A.L.2    Dusza, S.W.3
  • 23
    • 50249101750 scopus 로고    scopus 로고
    • Tetracycline to prevent epidermal growth factor receptor inhibitor-induced skin rashes: Results of a placebo-controlled trial from the North Central Cancer Treatment Group (N03CB)
    • A. Jatoi, K. Rowland, and J.A. Sloan et al. Tetracycline to prevent epidermal growth factor receptor inhibitor-induced skin rashes: results of a placebo-controlled trial from the North Central Cancer Treatment Group (N03CB) Cancer 113 2008 847 853
    • (2008) Cancer , vol.113 , pp. 847-853
    • Jatoi, A.1    Rowland, K.2    Sloan, J.A.3
  • 24
    • 77950495095 scopus 로고    scopus 로고
    • Skin toxicity evaluation protocol with panitumumab (STEPP), a phase II, open-label, randomized trial evaluating the impact of a pre-emptive skin treatment regimen on skin toxicities and quality of life in patients with metastatic colorectal cancer
    • M.E. Lacouture, E.P. Mitchell, and B. Piperdi et al. Skin toxicity evaluation protocol with panitumumab (STEPP), a phase II, open-label, randomized trial evaluating the impact of a pre-emptive skin treatment regimen on skin toxicities and quality of life in patients with metastatic colorectal cancer J Clin Oncol 28 2010 1351 1357
    • (2010) J Clin Oncol , vol.28 , pp. 1351-1357
    • Lacouture, M.E.1    Mitchell, E.P.2    Piperdi, B.3
  • 26
    • 33847012963 scopus 로고    scopus 로고
    • Acneiform eruptions associated with epidermal growth factor receptor-targeted chemotherapy
    • C.A. DeWitt, A.E. Siroy, and S.P. Stone Acneiform eruptions associated with epidermal growth factor receptor-targeted chemotherapy J Am Acad Dermatol 56 2007 500 505
    • (2007) J Am Acad Dermatol , vol.56 , pp. 500-505
    • Dewitt, C.A.1    Siroy, A.E.2    Stone, S.P.3
  • 27
    • 43749094998 scopus 로고    scopus 로고
    • The epidermal growth factor receptor system in skin repair and inflammation
    • S. Pastore, F. Mascia, and V. Mariani et al. The epidermal growth factor receptor system in skin repair and inflammation J Invest Dermatol 128 2008 1365 1374
    • (2008) J Invest Dermatol , vol.128 , pp. 1365-1374
    • Pastore, S.1    Mascia, F.2    Mariani, V.3
  • 28
    • 79952013114 scopus 로고    scopus 로고
    • Interdisciplinary management of EGFR-inhibitor-induced skin reactions: A German expert opinion
    • K. Potthoff, R. Hofheinz, and J.C. Hassel et al. Interdisciplinary management of EGFR-inhibitor-induced skin reactions: a German expert opinion Ann Oncol 22 2010 524 535
    • (2010) Ann Oncol , vol.22 , pp. 524-535
    • Potthoff, K.1    Hofheinz, R.2    Hassel, J.C.3
  • 29
    • 67649959737 scopus 로고    scopus 로고
    • The therapeutic potential of phosphatase inhibitors
    • V.V. Vintonyak, A.P. Antonchick, and D. Rauh et al. The therapeutic potential of phosphatase inhibitors Curr Opin Chem Biol 13 2009 272 283
    • (2009) Curr Opin Chem Biol , vol.13 , pp. 272-283
    • Vintonyak, V.V.1    Antonchick, A.P.2    Rauh, D.3
  • 30
    • 33749002673 scopus 로고    scopus 로고
    • Topical vitamin K3 (Vit K3, Menadione) prevents erlotinib and cetuximab-induced EGFR inhibition in the skin
    • abstract 3036
    • R. Perez-Soler, Y. Zou, and T. Li et al. Topical vitamin K3 (Vit K3, Menadione) prevents erlotinib and cetuximab-induced EGFR inhibition in the skin ASCO Annual Meeting Proceedings 2006 abstract 3036
    • (2006) ASCO Annual Meeting Proceedings
    • Perez-Soler, R.1    Zou, Y.2    Li, T.3
  • 31
    • 80455162338 scopus 로고    scopus 로고
    • The phosphatase inhibitor menadione (vitamin K3) protects cells from EGFR inhibition by erlotinib and cetuximab
    • R. Perez-Soler, Y. Zou, and T. Li et al. The phosphatase inhibitor menadione (vitamin K3) protects cells from EGFR inhibition by erlotinib and cetuximab Clin Cancer Res 17 2011 6766 6777
    • (2011) Clin Cancer Res , vol.17 , pp. 6766-6777
    • Perez-Soler, R.1    Zou, Y.2    Li, T.3
  • 32
    • 84895077129 scopus 로고    scopus 로고
    • Steroids and immunosuppressive agents potentiate the cytotoxicity of the EGFR inhibitor erlotinib in human keratinocytes whereas Vit K3 exerts a protective effect: Implications for the management of skin rash
    • abstract 9124
    • R. Perez-Soler, Y. Zou, and T. Li et al. Steroids and immunosuppressive agents potentiate the cytotoxicity of the EGFR inhibitor erlotinib in human keratinocytes whereas Vit K3 exerts a protective effect: implications for the management of skin rash ASCO Annual Meeting Proceedings 2007 abstract 9124
    • (2007) ASCO Annual Meeting Proceedings
    • Perez-Soler, R.1    Zou, Y.2    Li, T.3
  • 33
    • 84875369304 scopus 로고    scopus 로고
    • Phytomenadione pre-treatment in EGFR inhibitor-induced folliculitis
    • H. Tomkova, M. Pospiskova, and M. Zabojnikova et al. Phytomenadione pre-treatment in EGFR inhibitor-induced folliculitis J Eur Acad Dermatol Venereol 27 2013 514 519
    • (2013) J Eur Acad Dermatol Venereol , vol.27 , pp. 514-519
    • Tomkova, H.1    Pospiskova, M.2    Zabojnikova, M.3
  • 34
    • 77749296181 scopus 로고    scopus 로고
    • Management of cutaneous side-effects of cetuximab therapy in patients with metastatic colorectal cancer
    • J. Ocvirk, and S. Cencelj Management of cutaneous side-effects of cetuximab therapy in patients with metastatic colorectal cancer J Eur Acad Dermatol Venereol 24 2010 453 459
    • (2010) J Eur Acad Dermatol Venereol , vol.24 , pp. 453-459
    • Ocvirk, J.1    Cencelj, S.2
  • 36
    • 84895073408 scopus 로고    scopus 로고
    • 1 cream in the management of skin rash during anti-EGFR monoclonal antibody (mAb) treatment in patients with metastatic cancer: First analysis of an observational Italian study
    • abstract
    • 1 cream in the management of skin rash during anti-EGFR monoclonal antibody (mAb) treatment in patients with metastatic cancer: first analysis of an observational Italian study Gastrointestinal Cancers Symposium 2011 abstract
    • (2011) Gastrointestinal Cancers Symposium
    • Pinto, C.1
  • 37
  • 38
    • 12744281454 scopus 로고    scopus 로고
    • version 3.0. Accessed: September 21, 2013
    • Common Terminology Criteria for Adverse Events, version 3.0. Available at: ctep.cancer.gov/reporting/ctc.html. Accessed: September 21, 2013.
    • Common Terminology Criteria for Adverse Events
  • 39
    • 39149084687 scopus 로고    scopus 로고
    • Efficacy and skin toxicity management with cetuximab in metastatic colorectal cancer: Outcomes from an oncologic/dermatologic cooperation
    • P. Racca, L. Fanchini, and V. Caliendo et al. Efficacy and skin toxicity management with cetuximab in metastatic colorectal cancer: outcomes from an oncologic/dermatologic cooperation Clin Colorectal Cancer 7 2008 48 54
    • (2008) Clin Colorectal Cancer , vol.7 , pp. 48-54
    • Racca, P.1    Fanchini, L.2    Caliendo, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.