Elderly patients with CKD - Dilemmas in dialysis therapy and vascular access

Nature Reviews Nephrology

Volumn 10, Issue 2, 2014, Pages 116-122

  Vachharajani, Tushar J ^a   Moist, Louise M ^b   Glickman, Marc H ^c   Vazquez, Miguel A ^d   Polkinghorne, Kevan R ^e   Lok, Charmaine E ^f   Lee, Timmy C ^g  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b WESTERN UNIVERSITY   (Canada)

^c EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e MONASH MEDICAL CENTRE   (Australia)

^f UNIVERSITY OF TORONTO   (Canada)

^g University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; CATHETERS, INDWELLING; DECISION MAKING; HUMANS; KIDNEY FAILURE, CHRONIC; RENAL DIALYSIS;

EID: 84895072313     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2013.256     Document Type: Review

References (73)

1. Collins, A. J. et al. US Renal Data System 2012 Annual Data Report. Am. J. Kidney Dis. 61 (Suppl. 1), A7 (2013).
2. Brown, E. A. & Johansson, L. Epidemiology and management of end-stage renal disease in the elderly. Nat. Rev. Nephrol. 7, 591-598 (2011).
3. Prakash, S. & O'Hare, A. M. Interaction of aging and chronic kidney disease. Semin. Nephrol. 29, 497-503 (2009).
4. Kurella, M., Covinsky, K. E., Collins, A. J. & Chertow, G. M. Octogenarians and nonagenarians starting dialysis in the United States. Ann. Intern. Med. 146, 177-183 (2007).
5. Arnold, R. M. & Zeidel, M. L. Dialysis in frail elders - a role for palliative care. N. Engl. J. Med. 361, 1597-1598 (2009).
6. Carson, R. C., Juszczak, M., Davenport, A. & Burns, A. Is maximum conservative management an equivalent treatment option to dialysis for elderly patients with significant comorbid disease? Clin. J. Am. Soc. Nephrol. 4, 1611-1619 (2009).
7. Davison, S. N. Integrating palliative care for patients with advanced chronic kidney disease: recent advances, remaining challenges. J. Palliat. Care 27, 53-61 (2011).
8. Canaud, B. et al. Clinical practices and outcomes in elderly hemodialysis patients: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Clin. J. Am. Soc. Nephrol. 6, 1651-1662 (2011).
9. Tamura, M. K., Tan, J. C. & O'Hare, A. M. Optimizing renal replacement therapy in older adults: a framework for making individualized decisions. Kidney Int. 82, 261-269 (2012).
10. Canadian Institute for Health Information. Canadian organ replacement register annual report. Treatment of end stage organ failure in Canada, 2000 to 2009 [online], https://secure.cihi.ca/freeproducts/2011CORRAnnualReportfinale. pdf (2011).
11. DeSilva, R. N. et al. Fistula first is not always the best strategy for the elderly. J. Am. Soc. Nephrol. 24, 1297-1304 (2013).
12. Moosa, M. R. & Kidd, M. The dangers of rationing dialysis treatment: the dilemma facing a developing country. Kidney Int. 70, 1107-1114 (2006).
13. Rehman, R., Schmidt, R. J. & Moss, A. H. Ethical and legal obligation to avoid long-term tunneled catheter access. Clin. J. Am. Soc. Nephrol. 4, 456-460 (2009).
14. Quinn, R. R. et al. The Vascular Access Questionnaire: assessing patient-reported views of vascular access. J. Vasc. Access 9, 122-128 (2008).
15. Xi, W. et al. Patient attitudes towards the arteriovenous fistula: a qualitative study on vascular access decision making. Nephrol. Dial. Transplant. 26, 3302-3308 (2011).
16. Leermakers, J. J. et al. Cost-effectiveness of vascular access for haemodialysis: arteriovenous fistulas versus arteriovenous grafts. Eur. J. Vasc. Endovasc. Surg. 45, 84-92 (2013).
17. Xue, H., Lacson, E. Jr, Wang, W., Curhan, G. C. & Brunelli, S. M. Choice of vascular access among incident hemodialysis patients: a decision and cost-utility analysis. Clin. J. Am. Soc. Nephrol. 5, 2289-2296 (2010).
18. Rosas, S. E. & Feldman, H. I. Synthetic vascular hemodialysis access versus native arteriovenous fistula: a cost-utility analysis. Ann. Surg. 255, 181-186 (2012).
19. Moist, L. M. et al. Optimal hemodialysis vascular access in the elderly patient. Semin. Dial. 25, 640-648 (2012).
20. Joly, D. et al. Octogenarians reaching end-stage renal disease: cohort study of decision-making and clinical outcomes. J. Am. Soc. Nephrol. 14, 1012-1021 (2003).
21. Keith, D. S., Nichols, G. A., Gullion, C. M., Brown, J. B. & Smith, D. H. Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization. Arch. Intern. Med. 164, 659-663 (2004).
22. Kooman, J. P., Cornelis, T., van der Sande, F. M. & Leunissen, K. M. Renal replacement therapy in geriatric end-stage renal disease patients: a clinical approach. Blood Purif. 33, 171-176 (2012).
23. Murtagh, F. E., Cohen, L. M. & Germain, M. J. The "no dialysis" option. Adv. Chronic Kidney Dis. 18, 443-449 (2011).
24. Knauf, F. & Aronson, P. S. ESRD as a window into America's cost crisis in health care. J. Am. Soc. Nephrol. 20, 2093-2097 (2009).
25. Murtagh, F. E. et al. Dialysis or not? A comparative survival study of patients over 75 years with chronic kidney disease stage 5. Nephrol. Dial. Transplant. 22, 1955-1962 (2007).
26. Chandna, S. M. et al. Survival of elderly patients with stage 5 CKD: comparison of conservative management and renal replacement therapy. Nephrol. Dial. Transplant. 26, 1608-1614 (2011).
27. Murtagh, F. E., Addington-Hall, J. M. & Higginson, I. J. End-stage renal disease: a new trajectory of functional decline in the last year of life. J. Am. Geriatr. Soc. 59, 304-308 (2011).
28. Da Silva-Gane, M. et al. Quality of life and survival in patients with advanced kidney failure managed conservatively or by dialysis. Clin. J. Am. Soc. Nephrol. 7, 2002-2009 (2012).
29. Kurella Tamura, M. et al. Functional status of elderly adults before and after initiation of dialysis. N. Engl. J. Med. 361, 1539-1547 (2009).
30. Jassal, S. V., Chiu, E. & Hladunewich, M. Loss of independence in patients starting dialysis at 80 years of age or older. N. Engl. J. Med. 361, 1612-1613 (2009).
31. Burns, A. & Davenport, A. Functional status of elderly adults receiving dialysis. N. Engl. J. Med. 362, 468 (2010).
32. Noble, H., Meyer, J., Bridges, J., Kelly, D. & Johnson, B. Patient experience of dialysis refusal or withdrawal - a review of the literature. J. Ren. Care 34, 94-100 (2008).
33. Collins, A. J. et al. US Renal Data System 2010 Annual Data Report. Am. J. Kidney Dis. 57 (Suppl. 1), A8 (2011).
34. Mehrotra, R., Chiu, Y. W., Kalantar-Zadeh, K., Bargman, J. & Vonesh, E. Similar outcomes with hemodialysis and peritoneal dialysis in patients with end-stage renal disease. Arch. Intern. Med. 171, 110-118 (2011).
35. Weinhandl, E. D. et al. Propensity-matched mortality comparison of incident hemodialysis and peritoneal dialysis patients. J. Am. Soc. Nephrol. 21, 499-506 (2010).
36. Jaar, B. G. et al. Timing, causes, predictors and prognosis of switching from peritoneal dialysis to hemodialysis: a prospective study. BMC Nephrol. 10, 3 (2009).
37. Lim, W. H., Dogra, G. K., McDonald, S. P., Brown, F. G. & Johnson, D. W. Compared with younger peritoneal dialysis patients, elderly patients have similar peritonitis-free survival and lower risk of technique failure, but higher risk of peritonitis-related mortality. Perit. Dial. Int. 31, 663-671 (2011).
38. Wu, A. W. et al. Changes in quality of life during hemodialysis and peritoneal dialysis treatment: generic and disease specific measures. J. Am. Soc. Nephrol. 15, 743-753 (2004).
39. Praga, M. et al. Type of vascular access and survival among very elderly hemodialysis patients. Nephron Clin. Pract. 124, 47-53 (2013).
40. Perl, J. et al. Hemodialysis vascular access modifies the association between dialysis modality and survival. J. Am. Soc. Nephrol. 22, 1113-1121 (2011).
41. Lok, C. E. et al. Risk equation determining unsuccessful cannulation events and failure to maturation in arteriovenous fistulas (REDUCE FTM I). J. Am. Soc. Nephrol. 17, 3204-3212 (2006).
42. Richardson, A. I. 2nd et al. Should fistulas really be first in the elderly patient? J. Vasc. Access 10, 199-202 (2009).
43. Bass, E. B. et al. How strong are patients' preferences in choices between dialysis modalities and doses? Am. J. Kidney Dis. 44, 695-705 (2004).
44. Harris, S. A., Lamping, D. L., Brown, E. A., Constantinovici, N. & North Thames Dialysis Study (NTDS) Group. Clinical outcomes and quality of life in elderly patients on peritoneal dialysis versus hemodialysis. Perit. Dial. Int. 22, 463-470 (2002).
45. Belasco, A., Barbosa, D., Bettencourt, A. R., Diccini, S. & Sesso, R. Quality of life of family caregivers of elderly patients on hemodialysis and peritoneal dialysis. Am. J. Kidney Dis. 48, 955-963 (2006).
46. Foley, R. N. et al. Chronic kidney disease and the risk for cardiovascular disease, renal replacement, and death in the United States Medicare population, 1998 to 1999. J. Am. Soc. Nephrol. 16, 489-495 (2005).
47. O'Hare, A. M. et al. Age affects outcomes in chronic kidney disease. J. Am. Soc. Nephrol. 18, 2758-2765 (2007).
48. O'Hare, A. M. et al. When to refer patients with chronic kidney disease for vascular access surgery: should age be a consideration? Kidney Int. 71, 555-561 (2007).
49. Oliver, M. J. et al. Likelihood of starting dialysis after incident fistula creation. Clin. J. Am. Soc. Nephrol. 7, 466-471 (2012).
50. Cooper, B. A. et al. A randomized, controlled trial of early versus late initiation of dialysis. N. Engl. J. Med. 363, 609-619 (2010).
51. Eriksen, B. O. & Ingebretsen, O. C. The progression of chronic kidney disease: a 10-year population-based study of the effects of gender and age. Kidney Int. 69, 375-382 (2006).
52. Arteriovenous Fistula First. Fistula First Catheter (FF/CL) Data [online], http://www.fistulafirst.org/AboutFistulaFirst/ FisultaFirstCatheterLastFFCLData.aspx (2013).
53. Vascular Access Work Group. Clinical practice guidelines for vascular access. Am. J. Kidney Dis. 48 (Suppl. 1), S176-S247 (2006).
54. Vascular Access Work Group. Clinical practice guidelines for vascular access. Am. J. Kidney Dis. 48 (Suppl. 1), S248-S273 (2006).
55. Lee, T., Barker, J. & Allon, M. Comparison of survival of upper arm arteriovenous fistulas and grafts after failed forearm fistula. J. Am. Soc. Nephrol. 18, 1936-1941 (2007).
56. Lok, C. E. et al. Cumulative patency of contemporary fistulas versus grafts (2000-2010). Clin. J. Am. Soc. Nephrol. 8, 810-818 (2013).
57. Lok, C. E. et al. Arteriovenous fistula outcomes in the era of the elderly dialysis population. Kidney Int. 67, 2462-2469 (2005).
58. O'Hare, A. M. Vascular access for hemodialysis in older adults: a "patient first" approach. J. Am. Soc. Nephrol. 24, 1187-1190 (2013).
59. Keuter, X. H. et al. A randomized multicenter study of the outcome of brachial-basilic arteriovenous fistula and prosthetic brachial-antecubital forearm loop as vascular access for hemodialysis. J. Vasc. Surg. 47, 395-401 (2008).
60. Allon, M. Current management of vascular access. Clin. J. Am. Soc. Nephrol. 2, 786-800 (2007).
61. Lazarides, M. K., Georgiadis, G. S., Antoniou, G. A. & Staramos, D. N. A meta-analysis of dialysis access outcome in elderly patients. J. Vasc. Surg. 45, 420-426 (2007).
62. Weale, A. R. et al. Radiocephalic and brachiocephalic arteriovenous fistula outcomes in the elderly. J. Vasc. Surg. 47, 144-150 (2008).
63. Jindal, K. et al. Hemodialysis clinical practice guidelines for the Canadian Society of Nephrology. J. Am. Soc. Nephrol. 17 (Suppl. 1), S1-S27 (2006).
64. Vachharajani, T. J. et al. Re-evaluating the Fistula First Initiative in octogenarians on hemodialysis. Clin. J. Am. Soc. Nephrol. 6, 1663-1667 (2011).
65. Glickman, M. H. et al. Multicenter evaluation of a polytetrafluoroethylene vascular access graft as compared with the expanded polytetrafluoroethylene vascular access graft in hemodialysis applications. J. Vasc. Surg. 34, 465-472 (2001).
66. Garland, J. S. et al. Prevalence and associations of coronary artery calcification in patients with stages 3 to 5 CKD without cardiovascular disease. Am. J. Kidney Dis. 52, 849-858 (2008).
67. Hassan, N. A., D'Orsi, E. T., D'Orsi, C. J. & O'Neill, W. C. The risk for medial arterial calcification in CKD. Clin. J. Am. Soc. Nephrol. 7, 275-279 (2012).
68. Newman, A. B. et al. Coronary artery calcification in older adults to age 99: prevalence and risk factors. Circulation 104, 2679-2684 (2001).
69. Leon, C. & Asif, A. Arteriovenous access and hand pain: the distal hypoperfusion ischemic syndrome. Clin. J. Am. Soc. Nephrol. 2, 175-183 (2007).
70. Salman, L., Asif, A. & Beathard, G. A. Retrograde angiography and the risk of arteriovenous fistula perforation. Semin. Dial. 22, 698-701 (2009).
71. Zamani, P., Kaufman, J. & Kinlay, S. Ischemic steal syndrome following arm arteriovenous fistula for hemodialysis. Vasc. Med. 14, 371-376 (2009).
72. Davidson, D. et al. Steal syndrome complicating upper extremity hemoaccess procedures: incidence and risk factors. Can. J. Surg. 46, 408-412 (2003).
73. Rooijens, P. P. et al. Autogenous radial-cephalic or prosthetic brachial-antecubital forearm loop AVF in patients with compromised vessels? A randomized, multicenter study of the patency of primary hemodialysis access. J. Vasc. Surg. 42, 481-486 (2005).