Alignment of multiple glial cell populations in 3D nanofiber scaffolds: Toward the development of multicellular implantable scaffolds for repair of neural injury

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 10, Issue 2, 2014, Pages 291-295

  Weightman, Alan ^a   Jenkins, Stuart ^a   Pickard, Mark ^a   Chari, Divya ^a   Yang, Ying ^a  

^a KEELE UNIVERSITY   (United Kingdom)

Author keywords

3D implant; Electrospinning; Nanofiber scaffolds; Neural regeneration; Neuroglia

Indexed keywords

3D IMPLANT; ELECTROSPINNING; NANOFIBER SCAFFOLDS; NEURAL REGENERATION; NEUROGLIA;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; COCULTURE TECHNIQUES; HYDROGELS; MYELIN SHEATH; NANOFIBERS; NERVE REGENERATION; NEUROGLIA; NEURONS; OLIGODENDROGLIA; RATS; RATS, SPRAGUE-DAWLEY; STEM CELLS; TISSUE SCAFFOLDS;

EID: 84895067423     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2013.09.001     Document Type: Article

References (10)

1. Yiu G., He Z. Glial inhibition of CNS axon regeneration. Nat Rev Neurosci 2006, 7:617-627.
2. Shibuya S., Yamamoto T., Itano T. Glial and axonal regeneration following spinal cord injury. Cell Adh Migr 2009, 3:99-106.
3. Pfrieger F.W. Roles of glial cells in synapse development. Cell Mol Life Sci 2009, 66:2037-2047.
4. Gerardo-Nava J., Führmann T., Klinkhammer K., Seiler N., Mey J., Klee D., et al. Human neural cell interactions with orientated electrospun nanofibers in vitro. Nanomedicine (Lond) 2009, 4:11-30.
5. East E., de Oliveira D.B., Golding J.P., Phillips J.B. Alignment of astrocytes increases neuronal growth in three-dimensional collagen gels and is maintained following plastic compression to form a spinal cord repair conduit. Tissue Eng Part A 2010, 16:3173-3184.
6. McCarthy K.D., de Vellis J. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 1980, 85:890-902.
7. Yang Y., Wimpenny I., Ahearne M. Portable nanofiber meshes dictate cell orientation throughout three-dimensional hydrogels. Nanomedicine: NBM 2011, 7:131-136.
8. Kubinová S., Syková E. Biomaterials combined with cell therapy for treatment of spinal cord injury. Regen Med 2012, 7:207-224.
9. Wang D.D., Bordey A. The astrocyte odyssey. Prog Neurobiol 2008, 86:342-367.
10. Daud M.F., Pawar K.C., Claeyssens F., Ryan A.J., Haycock J.W. An aligned 3D neuronal-glial co-culture model for peripheral nerve studies. Biomaterials 2012, 33:5901-5913.