Prebiotic and probiotic supplementation prevents rhinovirus infections in preterm infants: A randomized, placebo-controlled trial

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 2, 2014, Pages 405-413

  Luoto, Raakel ^a   Ruuskanen, Olli ^a   Waris, Matti ^b   Kalliomäki, Marko ^a   Salminen, Seppo ^b   Isolauri, Erika ^a  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

Galacto oligosaccharide; gut microbiota; Lactobacillus rhamnosus GG; polydextrose; prebiotic; preterm infant; probiotic; respiratory tract infections; rhinovirus

Indexed keywords

GALACTO-OLIGOSACCHARIDE; GUT MICROBIOTA; LACTOBACILLUS RHAMNOSUS GG; POLYDEXTROSE; PREBIOTIC; PRETERM INFANT; PROBIOTIC; RATE RATIO; RESPIRATORY SYNCYTIAL VIRUS; RESPIRATORY TRACT INFECTION; RESPIRATORY TRACT INFECTIONS; RHINOVIRUS; RR; RSV; RTI;

DNA, VIRAL; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; INFANT, PREMATURE; MALE; PICORNAVIRIDAE INFECTIONS; PREBIOTICS; PROBIOTICS; RESPIRATORY TRACT DISEASES; RHINOVIRUS; VIRAL LOAD;

EID: 84895063754     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.08.020     Document Type: Article

References (37)

1. Food and Agriculture Organization of the United Nations, World Health Organization. Report of a joint FAO/WHO expert consultation on evaluation of health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria. Available at: www.who.int/entity/foodsafety/ publications/fs-management/en/probiotics.pdf. Accessed November 2009.
2. M. Pineiro, N.G. Asp, G. Reid, S. Macfarlane, L. Morelli, and O. Brunser et al. FAO Technical meeting on prebiotics J Clin Gastroenterol 42(Suppl 3 Pt 2) 2008 S156 S159
3. E.K. Vouloumanou, G.C. Makris, D.E. Karageorgopoulos, and M.E. Falagas Probiotics for the prevention of respiratory tract infections: a systematic review Int J Antimicrob Agents 34 2009 197
4. S. Weichert, H. Schroten, and R. Adam The role of prebiotics and probiotics in prevention and treatment of childhood infectious diseases Pediatr Infect Dis J 31 2012 859 862
5. A.A. Sharma, R. Jen, A. Butler, and P.M. Lavoie The developing human preterm neonatal immune system: a case for more research in this area Clin Immunol 145 2012 61 68
6. A. Pärtty, R. Luoto, M. Kalliomäki, S. Salminen, and E. Isolauri Effects of early prebiotic and probiotic supplementation on development of gut microbiota and fussing and crying in preterm infants: a randomized, double-blind, placebo-controlled trial J Pediatr 2013 Jul 31 [Epub ahead of print] doi:10.1016/j.jpeds.2013.05.035
7. V. Peltola, M. Waris, R. Osterback, P. Susi, O. Ruuskanen, and T. Hyypiä Rhinovirus transmission within families with children: incidence of symptomatic and asymptomatic infections J Infect Dis 197 2008 382 389
8. M. Koskenvuo, M. Möttönen, M. Waris, T. Allander, T.T. Salmi, and O. Ruuskanen Human bocavirus in children with acute lymphoblastic leukemia Eur J Pediatr 167 2008 1011 1015
9. N.J. McLeish, J. Witteveldt, L. Clasper, C. McIntyre, and Leitch EC. McWilliam et al. Development and assay of RNA transcripts of enterovirus species A to D, rhinovirus species A to C, and human parechovirus: assessment of assay sensitivity and specificity of real-time screening and typing methods J Clin Microbiol 50 2012 2910 2917
10. Z. Weizman, G. Asli, and A. Alsheikh Effect of a probiotic infant formula on infections in child care centers: comparison of two probiotic agents Pediatrics 115 2005 5 9
11. S. Arslanoglu, G.E. Moro, and G. Boehm Early supplementation of prebiotic oligosaccharides protects formula-fed infants against infections during the first 6 months of life J Nutr 137 2007 2420 2424
12. S. Arslanoglu, G.E. Moro, J. Schmitt, L. Tandoi, S. Rizzardi, and G. Boehm Early dietary intervention with a mixture of prebiotic oligosaccharides reduces the incidence of allergic manifestations and infections during the first two years of life J Nutr 138 2008 1091 1095
13. K. Kukkonen, E. Savilahti, T. Haahtela, K. Juntunen-Backman, R. Korpela, and T. Poussa et al. Long-term safety and impact on infection rates of postnatal probiotic and prebiotic (synbiotic) treatment: randomized, double-blind, placebo-controlled trial Pediatrics 122 2008 8 12
14. S. Rautava, S. Salminen, and E. Isolauri Specific probiotics in reducing the risk of acute infections in infancy-a randomised, double-blind, placebo-controlled study Br J Nutr 101 2009 1722 1726
15. T. Taipale, K. Pienihäkkinen, E. Isolauri, C. Larsen, E. Brockmann, and P. Alanen et al. Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in infancy Br J Nutr 105 2011 409 416
16. J. Maldonado, F. Cañabate, L. Sempere, F. Vela, A.R. Sánchez, and E. Narbona et al. Human milk probiotic Lactobacillus fermentum CECT5716 reduces the incidence of gastrointestinal and upper respiratory tract infections in infants J Pediatr Gastroenterol Nutr 54 2012 55 61
17. M. Gil-Campos, MÁ López, M.V. Rodriguez-Benítez, J. Romero, I. Roncero, and M.D. Linares et al. Lactobacillus fermentum CECT 5716 is safe and well tolerated in infants of 1-6 months of age: a randomized controlled trial Pharmacol Res 65 2012 231 238
18. M. Kalliomäki, S. Salminen, T. Poussa, and E. Isolauri Probiotics during the first 7 years of life: a cumulative risk reduction of eczema in a randomized, placebo-controlled trial J Allergy Clin Immunol 119 2007 1019 1021
19. L.V. Hooper, D.R. Littman, and A.J. Macpherson Interactions between the microbiota and the immune system Science 336 2012 1268 1273
20. T. Olszak, D. An, S. Zeissig, M.P. Vera, J. Richter, and A. Franke et al. Microbial exposure during early life has persistent effects on natural killer T cell function Science 336 2012 489 493
21. J.J. Faith, J.L. Guruge, M. Charbonneau, S. Subramanian, H. Seedorf, and A.L. Goodman et al. The long-term stability of the human gut microbiota Science 341 2013 1237439
22. T. Jartti, and M. Korppi Rhinovirus-induced bronchiolitis and asthma development Pediatr Allergy Immunol 22 2011 350 355
23. U. Glück, and J.O. Gebbers Ingested probiotics reduce nasal colonization with pathogenic bacteria (Staphylococcus aureus, Streptococcus pneumoniae, and beta-hemolytic streptococci) Am J Clin Nutr 77 2003 517 520
24. T. Ichinohe, I.K. Pang, Y. Kumamoto, D.R. Peaper, J.H. Ho, and T.S. Murray et al. Microbiota regulates immune defense against respiratory tract influenza A virus infection Proc Natl Acad Sci U S A 108 2011 5354 5359
25. M.G. Gareau, P.M. Sherman, and W.A. Walker Probiotics and the gut microbiota in intestinal health and disease Nat Rev Gastroenterol Hepatol 7 2010 503 514
26. K. Ganguli, D. Meng, S. Rautava, L. Lu, W.A. Walker, and N. Nanthakumar Probiotics prevent necrotizing enterocolitis by modulating enterocyte genes that regulate innate immune-mediated inflammation Am J Physiol Gastrointest Liver Physiol 304 2013 G132 G141
27. J. Villena, E. Chiba, Salva S. Tomosada, G. Marranzino, and H. Kitazawa et al. Orally administered Lactobacillus rhamnosus modulates the respiratory immune response triggered by the viral pathogen-associated molecular pattern poly(I: C) BMC Immunol 13 2012 53
28. C. Archambaud, M.A. Nahori, Bécavin C. Soubigou, L. Laval, and P. Lechat et al. Impact of lactobacilli on orally acquired listeriosis Proc Natl Acad Sci U S A 109 2012 16684 16689
29. P. Brandtzaeg The mucosal immune system and its integration with the mammary glands J Pediatr 156 suppl 2010 S8 S15
30. S.E. Jacobs, D.M. Lamson, K. St George, and T.J. Walsh Human rhinoviruses Clin Microbiol Rev 26 2012 135 162
31. O. Ruuskanen, M. Waris, and O. Ramilo New aspects on human rhinovirus infections Pediatr Infect Dis J 32 2013 553 555
32. R.R. Jansen, J. Wieringa, S.M. Koekkoek, C.E. Visser, D. Pajkrt, and R. Molenkamp et al. Frequent detection of respiratory viruses without symptoms: toward defining clinically relevant cutoff values J Clin Microbiol 49 2011 2631 2636
33. L.R. Krilov, L.B. Weiner, R. Yogev, J. Fergie, B.Z. Katz, and K.J. Henrickson et al. The 2009 COID recommendations for RSV prophylaxis: issues of efficacy, cost, and evidence-based medicine Pediatrics 124 2009 1682 1684
34. M.O. Blanken, M.M. Rovers, J.M. Molenaar, P.L. Winkler-Seinstra, A. Meijer, and J.L. Kimpen et al. Respiratory syncytial virus and recurrent wheeze in healthy preterm infants N Engl J Med 368 2013 1791 1799
35. R.O. van Piggelen, A.M. van Loon, T.G. Krediet, and M.A. Verboon-Maciolek Human rhinovirus causes severe infection in preterm infants Pediatr Infect Dis J 29 2010 364 365
36. E.K. Miller, J. Bugna, R. Libster, B.E. Shepherd, P.M. Scalzo, and P.L. Acosta et al. Human rhinoviruses in severe respiratory disease in very low birth weight infants Pediatrics 129 2012 e60 e67
37. Q. Hao, Z. Lu, B.R. Dong, C.Q. Huang, and T. Wu Probiotics for preventing acute upper respiratory tract infections Cochrane Database Syst Rev 9 2011 CD006895