Detrimental effects of metronidazole on selected innate immunological indicators in common carp (Cyprinus carpio L.)

Bulletin of Environmental Contamination and Toxicology

Volumn 92, Issue 2, 2014, Pages 196-201

  Han, Junyan ^a   Zhang, Lizhu ^a   Yang, Shaobin ^a   Wang, Jun ^a   Tan, Dehong ^b  

^a SHENYANG UNIVERSITY   (China)

^b SHENYANG AGRICULTURAL UNIVERSITY   (China)

Author keywords

Fish; Innate immunity; Metronidazole; Pharmaceuticals; Respiratory burst

Indexed keywords

ANTIINFECTIVE AGENT; METRONIDAZOLE;

ANIMAL; ARTICLE; CARP; CYTOLOGY; DRUG EFFECT; IMMUNOLOGY; INNATE IMMUNITY; KIDNEY; PHYSIOLOGY; TOXICITY TESTING; WATER POLLUTANT;

ANIMALS; ANTI-INFECTIVE AGENTS; CARPS; IMMUNITY, INNATE; KIDNEY; METRONIDAZOLE; TOXICITY TESTS; WATER POLLUTANTS, CHEMICAL;

EID: 84895008855     PISSN: 00074861     EISSN: 14320800     Source Type: Journal    
DOI: 10.1007/s00128-013-1173-6     Document Type: Article

References (24)

1. Bols NC, Brubacher JL, Ganassin RC, Lee LEJ (2001) Ecotoxicology and innate immunity in fish. Dev Comp Immunol 25:853-873 (Pubitemid 32780995)
2. El-Nahas AF, El-Ashmawy IM (2004) Reproductive and cytogenetic toxicity of metronidazole in male mice. Pharmacol Toxicol 94:226-231 (Pubitemid 38667868)
3. Fang Z, Chen J, Qiu X, Qiu X, Cheng W, Zhu L (2011) Effective removal of antibiotic metronidazole from water by nanoscale zero-valent iron particles. Desalination 268(1):60-67
4. Fararjeh M, Mohammad MK, Bustanji Y, AlKhatib H, Abdalla S (2008) Evaluation of immunosuppression induced by metronidazole in Balb/c mice and human peripheral blood lymphocytes. Int J Immunopharmacol 8:341-350
5. Guardiola F, Cerezuela R, Meseguer J, Esteban M (2012) Modulation of the immune parameters and expression of genes of gilthead seabream (Sparus aurata L.) by dietary administration of oxytetracycline. Aquaculture 334-337:51-57
6. Hamoutene D, Payne J, Volkoff H (2008) Effects of tebufenozide on some aspects of lake trout (Salvelinus namaycush) immune response. Ecotoxicol Environ Saf 69:173-179 (Pubitemid 350182455)
7. Han J, Cai H, Wang J, Liu G (2013) Detrimental Effects of Metronidazole on the Liver of Freshwater Common Carp (Cyprinus carpio L.). Bull Environ Contam Toxicol 91:444-449
8. Isidori M, Nardelli A, Parrella A, Pascarella L, Previtera L (2006) A multispecies study to assess the toxic and genotoxic effect of pharmaceuticals: furosemide and its photoproduct. Chemosphere 63:785-793
9. Kollner B, Wasserrab B, Kotterba G, Fischer U (2002) Evaluation of immune functions of rainbow trout (Oncorhynchus mykiss) - how can environmental influences be detected? Toxicol Lett 131:83-95 (Pubitemid 34464096)
10. Kum C, Sekkin S (2011) The immune system drugs in fish: immune function, immunoassay, drugs, recent advances in fish farms, Dr. Faruk Aral (Ed.), ISBN: 978-953-307-759-8, InTech
11. Li ZH, Velisek J, Zlabek V, Grabic R, Machova J, Kolarova J et al (2011) Chronic toxicity of verapamil on juvenile rainbow trout (Oncorhynchus mykiss): effects on morphological indices, hematological parameters and antioxidant responses. J Hazard Mater 185:870-880
12. Lunden T, Bylund G (2002) Effect of sulphadiazine and trimethoprim on the immune response of rainbow trout (Oncorhynchus mykiss). Vet Immunol Immunopathol 85:99-108 (Pubitemid 34175080)
13. Lunden T, Lilius EM, Bylund G (2002) Respiratory burst activity of rainbow trout (Oncorhynchus mykiss) phagocytes is modulated by antimicrobial drugs. Aquaculture 207:203-212 (Pubitemid 34548660)
14. Maher HM, Youssef RM, Khalil RH, El-Bahr SM (2008) Simultaneous multiresidue determination of metronidazole and spiramycin in fish muscle using high performance liquid chromatography with UV detection. J Chromatogr B 876:175-181
15. Nayak A, Das B, Kohli M, Mukherjee S (2004) The immunosuppressive effect of α-permethrin on Indian major carp, rohu (Labeo rohita Ham.). Fish Shellfish Immunol 16:41-50 (Pubitemid 38086332)
16. Nishimuta K, Ito Y (2003) Effects of metronidazole and tinidazole ointments on models for inflammatory dermatitis in mice. Arch Dermatol Res 294:544-551 (Pubitemid 36384684)
17. Rizzo A, Paolillo R, Guida L, Annunziata M, Bevilacqua N, Tufano MA (2010) Effect of metronidazole and modulation of cytokine production on human periodontal ligament cells. Int Immunopharmacol 10:744-750
18. Rodriguez L, Livengood EJ, Miles RD, Chapman FA (2011) Uptake of metronidazole in Artemia at different developmental life stages. J Aquat Anim Health 23:100-102
19. Salo HM, Hebert N, Dautremepuits C, Cejka P, Cyr DG, Fournier M (2007) Effects of montreal municipal sewage effluents on immune responses of juvenile female rainbow trout (Oncorhynchus mykiss). Aquatic Toxicol 84:406-414 (Pubitemid 47331690)
20. Shemer H, Kunukcu YK, Linden KG (2006) Degradation of the pharmaceutical metronidazole via UV, Fenton and photo-Fenton processes. Chemosphere 63:269-276
21. Theophilus J, Rao P (2011) Electrophoretic studies on the serum proteins of the three species of genus Channa. Indian J Fish 35:294-297
22. Wang GX, Wang Y, Wu ZF, Jiang HF, Dong RQ, Li FY, Liu XL (2011) Immunomodulatory effects of secondary metabolites from thermophilic Anoxybacillus kamchatkensis XA-1 on carp, Cyprinus carpio. Fish Shellfish Immunol 30:1331-1338
23. West AP, Shadel GS, Ghosh S (2011) Mitochondria in innate immune responses. Nat Rev Immunol 11(6):389-402
24. Whyte SK (2007) The innate immune response of finfish - a review of current knowledge. Fish Shellfish Immunol 23:1127-1151 (Pubitemid 350030541)