A role for c-Kit in the maintenance of undifferentiated human mesenchymal stromal cells

Biomaterials

Volumn 35, Issue 11, 2014, Pages 3618-3626

  Suphanantachat, Supreda ^a,b   Iwata, Takanori ^b   Ishihara, Jun ^b,c   Yamato, Masayuki ^b   Okano, Teruo ^b   Izumi, Yuichi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b Tokyo Women s Medical University Waseda University Joint Institution for Advanced Biomedical Sciences   (Japan)

^c THE UNIVERSITY OF TOKYO   (Japan)

Author keywords

C Kit receptor; Cell differentiation; Growth factors; Mesenchymal stromal cells; Periodontal ligament; Stem cell factor

Indexed keywords

CELL CULTURE; LIGAMENTS; PHOSPHATASES; STEM CELLS; TISSUE ENGINEERING; TRANSCRIPTION;

CELL DIFFERENTIATION; GROWTH FACTOR; MESENCHYMAL STROMAL CELLS; PERIODONTAL LIGAMENT; STEM CELL FACTOR;

CELL ENGINEERING;

ALKALINE PHOSPHATASE; ENAMEL PROTEIN; FIBROBLAST GROWTH FACTOR 2; LIPOPROTEIN LIPASE; MESSENGER RNA; OSTEOCALCIN; OSTEOPONTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA1;

ADIPOCYTE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE REPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MESENCHYMAL STROMA CELL; OSTEOBLAST; PRIORITY JOURNAL; UPREGULATION;

C-KIT RECEPTOR; CELL DIFFERENTIATION; GROWTH FACTORS; MESENCHYMAL STROMAL CELLS; PERIODONTAL LIGAMENT; STEM CELL FACTOR;

ADIPOGENESIS; ALKALINE PHOSPHATASE; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTORS, FIBROBLAST GROWTH FACTOR; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, MESSENGER; RNA, SMALL INTERFERING; STEM CELL FACTOR;

EID: 84894933732     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.01.031     Document Type: Article

References (43)

1. Gay I.C., Chen S., MacDougall M. Isolation and characterization of multipotent human periodontal ligament stem cells. Orthod Craniofac Res 2007, 10:149-160.
2. Iwata T., Yamato M., Tsuchioka H., Takagi R., Mukobata S., Washio K., et al. Periodontal regeneration with multi-layered periodontal ligament-derived cell sheets in a canine model. Biomaterials 2009, 30:2716-2723.
3. Iwata T., Yamato M., Zhang Z., Mukobata S., Washio K., Ando T., et al. Validation of human periodontal ligament-derived cells as a reliable source for cytotherapeutic use. JClin Periodontol 2010, 37:1088-1099.
4. Lindroos B., Maenpaa K., Ylikomi T., Oja H., Suuronen R., Miettinen S. Characterisation of human dental stem cells and buccal mucosa fibroblasts. Biochem Biophys Res Commun 2008, 368:329-335.
5. Seo B.M., Miura M., Gronthos S., Bartold P.M., Batouli S., Brahim J., et al. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 2004, 364:149-155.
6. Xu J., Wang W., Kapila Y., Lotz J., Kapila S. Multiple differentiation capacity of STRO-1+/CD146+ PDL mesenchymal progenitor cells. Stem Cells Dev 2009, 18:487-496.
7. Murakami Y., Kojima T., Nagasawa T., Kobayashi H., Ishikawa I. Novel isolation of alkaline phosphatase-positive subpopulation from periodontal ligament fibroblasts. JPeriodontol 2003, 74:780-786.
8. Crisan M., Yap S., Casteilla L., Chen C.W., Corselli M., Park T.S., et al. Aperivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 2008, 3:301-313.
9. Caplan A.I., Correa D. The MSC: an injury drugstore. Cell Stem Cell 2011, 9:11-15.
10. Shi S., Gronthos S. Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp. JBone Miner Res 2003, 18:696-704.
11. Dennis J.E., Carbillet J.P., Caplan A.I., Charbord P. The STRO-1+ marrow cell population is multipotential. Cells Tissues Organs 2002, 170:73-82.
12. Quirici N., Soligo D., Bossolasco P., Servida F., Lumini C., Deliliers G.L. Isolation of bone marrow mesenchymal stem cells by anti-nerve growth factor receptor antibodies. Exp Hematol 2002, 30:783-791.
13. Yarden Y., Kuang W.J., Yang-Feng T., Coussens L., Munemitsu S., Dull T.J., et al. Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J 1987, 6:3341-3351.
14. Williams D.E., Eisenman J., Baird A., Rauch C., Van Ness K., March C.J., et al. Identification of a ligand for the c-kit proto-oncogene. Cell 1990, 63:167-174.
15. Zsebo K.M., Wypych J., McNiece I.K., Lu H.S., Smith K.A., Karkare S.B., et al. Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium. Cell 1990, 63:195-201.
16. Kitamura Y., Hirotab S. Kit as a human oncogenic tyrosine kinase. Cell Mol Life Sci 2004, 61:2924-2931.
17. Blume-Jensen P., Claesson-Welsh L., Siegbahn A., Zsebo K.M., Westermark B., Heldin C.H. Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis. EMBO J 1991, 10:4121-4128.
18. Ashman L.K. The biology of stem cell factor and its receptor C-kit. Int J Biochem Cell Biol 1999, 31:1037-1051.
19. Broudy V.C., Lin N., Zsebo K.M., Birkett N.C., Smith K.A., Bernstein I.D., et al. Isolation and characterization of a monoclonal antibody that recognizes the human c-kit receptor. Blood 1992, 79:338-346.
20. Kajstura J., Rota M., Hall S.R., Hosoda T., D'Amario D., Sanada F., et al. Evidence for human lung stem cells. NEngl J Med 2011, 364:1795-1806.
21. Sakaguchi Y., Sekiya I., Yagishita K., Muneta T. Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source. Arthritis Rheum 2005, 52:2521-2529.
22. Bearzi C., Rota M., Hosoda T., Tillmanns J., Nascimbene A., De Angelis A., et al. Human cardiac stem cells. Proc Natl Acad Sci U S A 2007, 104:14068-14073.
23. Haynesworth S.E., Baber M.A., Caplan A.I. Cytokine expression by human marrow-derived mesenchymal progenitor cells invitro: effects of dexamethasone and IL-1 alpha. JCell Physiol 1996, 166:585-592.
24. Wagers A.J. The stem cell niche in regenerative medicine. Cell Stem Cell 2012, 10:362-369.
25. Haase H.R., Bartold P.M. Enamel matrix derivative induces matrix synthesis by cultured human periodontal fibroblast cells. JPeriodontol 2001, 72:341-348.
26. Oates T.W., Rouse C.A., Cochran D.L. Mitogenic effects of growth factors on human periodontal ligament cells invitro. JPeriodontol 1993, 64:142-148.
27. Takayama S., Murakami S., Miki Y., Ikezawa K., Tasaka S., Terashima A., et al. Effects of basic fibroblast growth factor on human periodontal ligament cells. JPeriodontal Res 1997, 32:667-675.
28. Murakami S. Periodontal tissue regeneration by signaling molecule(s): what role does basic fibroblast growth factor (FGF-2) have in periodontal therapy?. Periodontol 2000 2011, (56):188-208.
29. Washio K., Iwata T., Mizutani M., Ando T., Yamato M., Okano T., et al. Assessment of cell sheets derived from human periodontal ligament cells: a pre-clinical study. Cell Tissue Res 2010, 341:397-404.
30. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 2001, 25:402-408.
31. Bianco P., Robey P.G., Simmons P.J. Mesenchymal stem cells: revisiting history, concepts, and assays. Cell Stem Cell 2008, 2:313-319.
32. Dominici M., Le Blanc K., Mueller I., Slaper-Cortenbach I., Marini F., Krause D., et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The international society for cellular therapy position statement. Cytotherapy 2006, 8:315-317.
33. Majumdar M.K., Thiede M.A., Mosca J.D., Moorman M., Gerson S.L. Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells. JCell Physiol 1998, 176:57-66.
34. Muguruma Y., Yahata T., Miyatake H., Sato T., Uno T., Itoh J., et al. Reconstitution of the functional human hematopoietic microenvironment derived from human mesenchymal stem cells in the murine bone marrow compartment. Blood 2006, 107:1878-1887.
35. Nagatomo K., Komaki M., Sekiya I., Sakaguchi Y., Noguchi K., Oda S., et al. Stem cell properties of human periodontal ligament cells. JPeriodontal Res 2006, 41:303-310.
36. Hayami T., Zhang Q., Kapila Y., Kapila S. Dexamethasone's enhancement of osteoblastic markers in human periodontal ligament cells is associated with inhibition of collagenase expression. Bone 2007, 40:93-104.
37. Aubin J.E. Regulation of osteoblast formation and function. Rev Endocr Metab Disord 2001, 2:81-94.
38. Rosen E.D., Walkey C.J., Puigserver P., Spiegelman B.M. Transcriptional regulation of adipogenesis. Genes Dev 2000, 14:1293-1307.
39. Lee H.K., Lee B.H., Park S.A., Kim C.W. The proteomic analysis of an adipocyte differentiated from human mesenchymal stem cells using two-dimensional gel electrophoresis. Proteomics 2006, 6:1223-1229.
40. Muraglia A., Cancedda R., Quarto R. Clonal mesenchymal progenitors from human bone marrow differentiate invitro according to a hierarchical model. JCell Sci 2000, 113(Pt 7):1161-1166.
41. Caplan A.I. Mesenchymal stem cells. JOrthop Res 1991, 9:641-650.
42. Pittenger M.F., Mackay A.M., Beck S.C., Jaiswal R.K., Douglas R., Mosca J.D., et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999, 284:143-147.
43. Dey D., Han L., Bauer M., Sanada F., Oikonomopoulos A., Hosoda T., et al. Dissecting the molecular relationship among various cardiogenic progenitor cells. Circ Res 2013, 112:1253-1262.