Microsatellite polymorphism in the heme oxygenase-1 gene promoter is not associated with alcoholic liver disease severity

Hepatology

Volumn 59, Issue 1, 2014, Pages 352-353

  Lemaire, Anne ^a   Trépo, Eric ^a,b   Ouziel, Romy ^a,b   Gustot, Thierry ^a,b   Moreno, Christophe ^a,b   Degré, Delphine ^a,b   Minsart, Charlotte ^a   Quertinmont, Eric ^a   Vercruysse, Vincent ^a   De Wilde, Virginie ^b   Le Moine, Olivier ^b   Devière, Jacques ^a,b   Abramowicz, Marc ^a,b   Le Moine, Alain ^a,b   Lemmers, Arnaud ^a,b  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b ERASME HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

HEME OXYGENASE 1; MICROSATELLITE DNA;

ALCOHOL LIVER CIRRHOSIS; ALCOHOL LIVER DISEASE; DISEASE SEVERITY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HEME OXYGENASE 1 GENE; HOMOZYGOTE; HUMAN; LETTER; MICROSATELLITE INSTABILITY; MODEL FOR END STAGE LIVER DISEASE SCORE; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; ADULT; AGED; ANIMAL; FEMALE; GENETICS; MALE; MIDDLE AGED; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; FEMALE; HEME OXYGENASE-1; HUMANS; LIVER DISEASES, ALCOHOLIC; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC;

EID: 84894882582     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26534     Document Type: Letter

References (6)

1. Barikbin R, Neureiter D, Wirth J, Erhardt A, Schwinge D, Kluwe J, et al. Induction of heme oxygenase 1 prevents progression of liver fibrosis in Mdr2 knockout mice. Hepatology 2012;55:553-62.
2. Mandal P, Park PH, McMullen MR, Pratt BT, Nagy LE. The anti-inflammatory effect of adiponectin are mediated via a heme oxygenase-1-dependent pathway in rat Kuppfer cells. Hepatology 2010;51:1420-1429.
3. Louvet A, Teixeria-Clerc F, Chobert MN, Deveaux V, Pavoine C, Zimmer A, et al. Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice. Hepatology 2011;54:1217-1226.
4. Exner M, Minar E, Wagner O, Schillinger M. The role of heme oxygenase-1 promoter polymorphisms in human disease. Free Radic Biol Med 2004;37:1097-1104.
5. Yamada N, Yamaya M, Okinaga S, Nakayama K, Sekizawa K, Shibahara S, et al. Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. Am J Hum Genet 2000;66:187-195.
6. Trépo E, Gustot T, Degré D, Lemmers A, Verset L, Demetter P, et al. Common polymorphism in the PNPLA3/adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease. J Hepatol 2011;55:906-912.