메뉴 건너뛰기




Volumn 32, Issue 2, 2014, Pages 65-67

Dose-finding trial designs for combination therapies in oncology

Author keywords

[No Author keywords available]

Indexed keywords

NERATINIB; TEMSIROLIMUS; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERBB2 PROTEIN, HUMAN;

EID: 84894872013     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2013.52.9198     Document Type: Editorial
Times cited : (26)

References (19)
  • 1
    • 84894807977 scopus 로고    scopus 로고
    • Phase I study of neratinib in combination with temsirolimus in patients with human epidermal growth factor receptor 2-dependent and other solid tumors
    • Gandhi L, Bahleda R, Tolaney SM, et al: Phase I study of neratinib in combination with temsirolimus in patients with human epidermal growth factor receptor 2-dependent and other solid tumors. J Clin Oncol 32:68-75, 2014
    • (2014) J Clin Oncol , vol.32 , pp. 68-75
    • Gandhi, L.1    Bahleda, R.2    Tolaney, S.M.3
  • 2
    • 2942739164 scopus 로고    scopus 로고
    • A non-parametric approach to the design and analysis of two-dimensional dose-finding trials
    • DOI 10.1002/sim.1796
    • Ivanova A, Wang K: A non-parametric approach to the design and analysis of two-dimensional dose-finding trials. Stat Med 23:1861-1870, 2004 (Pubitemid 38787088)
    • (2004) Statistics in Medicine , vol.23 , Issue.12 , pp. 1861-1870
    • Ivanova, A.1    Wang, K.2
  • 3
    • 0024452804 scopus 로고
    • Design and analysis of phase I clinical trials
    • Storer BE: Design and analysis of phase I clinical trials. Biometrics 45:925-937, 1989
    • (1989) Biometrics , vol.45 , pp. 925-937
    • Storer, B.E.1
  • 4
    • 0041833622 scopus 로고    scopus 로고
    • Dose-finding with two agents in Phase I oncology trials
    • DOI 10.1111/1541-0420.00058
    • Thall PF, Millikan RE, Mueller P, et al: Dose-finding with two agents in phase I oncology trials. Biometrics 59:487-496, 2003 (Pubitemid 37093387)
    • (2003) Biometrics , vol.59 , Issue.3 , pp. 487-496
    • Thall, P.F.1    Millikan, R.E.2    Mueller, P.3    Lee, S.-J.4
  • 5
    • 4444244983 scopus 로고    scopus 로고
    • Designs for single- or multiple-agent phase I trials
    • DOI 10.1111/j.0006-341X.2004.00215.x
    • Conaway MR, Dunbar S, Peddada SD: Designs for single- or multiple-agent phase I trials. Biometrics 60:661-669, 2004 (Pubitemid 39181110)
    • (2004) Biometrics , vol.60 , Issue.3 , pp. 661-669
    • Conaway, M.R.1    Dunbar, S.2    Peddada, S.D.3
  • 6
    • 15044354311 scopus 로고    scopus 로고
    • Two-dimensional dose finding in discrete dose space
    • DOI 10.1111/j.0006-341X.2005.030540.x
    • Wang K, Ivanova A: Two-dimensional dose finding in discrete dose space. Biometrics 61:217-222, 2005 (Pubitemid 40380982)
    • (2005) Biometrics , vol.61 , Issue.1 , pp. 217-222
    • Wang, K.1    Ivanova, A.2
  • 7
    • 78049256742 scopus 로고    scopus 로고
    • Dose-escalation models for combination phase I trials in oncology
    • Hamberg P, Ratain MJ, Lesaffre E, et al: Dose-escalation models for combination phase I trials in oncology. Eur J Cancer 46:2870-2878, 2010
    • (2010) Eur J Cancer , vol.46 , pp. 2870-2878
    • Hamberg, P.1    Ratain, M.J.2    Lesaffre, E.3
  • 8
    • 0026362859 scopus 로고
    • Selecting combinations of chemotherapeutic drugs to maximize dose intensity
    • Simon R, Korn EL: Selecting combinations of chemotherapeutic drugs to maximize dose intensity. J Biopharm Stat 247-258, 1991
    • (1991) J Biopharm Stat , pp. 247-258
    • Simon, R.1    Korn, E.L.2
  • 9
    • 63849316345 scopus 로고    scopus 로고
    • Bayesian dose-finding in oncology for drug combinations by copula regression
    • Yin G, Yuan Y: Bayesian dose-finding in oncology for drug combinations by copula regression. J R Stat Soc: Series C (Applied Statistics) 58:211-224, 2009
    • (2009) J R Stat Soc: Series C (Applied Statistics) , vol.58 , pp. 211-224
    • Yin, G.1    Yuan, Y.2
  • 10
    • 0001553174 scopus 로고
    • An algorithm for isotonic regression for two or more independent variables
    • Dykstra R, Robertson T: An algorithm for isotonic regression for two or more independent variables. Ann Stat 10:708-716, 1982
    • (1982) Ann Stat , vol.10 , pp. 708-716
    • Dykstra, R.1    Robertson, T.2
  • 11
    • 0025148278 scopus 로고
    • Continual reassessment method: A practical design for phase 1 clinical trials in cancer
    • DOI 10.2307/2531628
    • O'Quigley J, Pepe M, Fisher L: Continual reassessment method: A practical design for phase 1 clinical trials in cancer. Biometrics 46:33-48, 1990 (Pubitemid 20245604)
    • (1990) Biometrics , vol.46 , Issue.1 , pp. 33-48
    • O'Quigley, J.1    Pepe, M.2    Fisher, L.3
  • 12
    • 33746402001 scopus 로고    scopus 로고
    • Consistency of continual reassessment method under model misspecification
    • Shen LZ, O'Quigley J: Consistency of continual reassessment method under model misspecification. Biometrika 83:395-405, 1996
    • (1996) Biometrika , vol.83 , pp. 395-405
    • Shen, L.Z.1    O'Quigley, J.2
  • 14
    • 77951528602 scopus 로고    scopus 로고
    • Model-based phase I designs incorporating toxicity and efficacy for single and dual agent drug combinations: Methods and challenges
    • Mandrekar SJ, Qin R, Sargent DJ: Model-based phase I designs incorporating toxicity and efficacy for single and dual agent drug combinations: Methods and challenges. Stat Med 29:1077-1083, 2010
    • (2010) Stat Med , vol.29 , pp. 1077-1083
    • Mandrekar, S.J.1    Qin, R.2    Sargent, D.J.3
  • 15
    • 84905681807 scopus 로고    scopus 로고
    • CRM trials for assessing toxicity and efficacy
    • John Crowley, Antje Hoering: Boca Raton, FL, CRC Press
    • Mandrekar SJ, Sargent DJ: CRM trials for assessing toxicity and efficacy, in John Crowley, Antje Hoering: Handbook of Statistics in Clinical Oncology (ed 3). Boca Raton, FL, CRC Press, 2012, pp 85-96
    • (2012) Handbook of Statistics in Clinical Oncology (Ed 3) , pp. 85-96
    • Mandrekar, S.J.1    Sargent, D.J.2
  • 16
    • 34547659861 scopus 로고    scopus 로고
    • A parallel phase I/II clinical trial design for combination therapies
    • Huang X, Biswas S, Oki Y, et al: A parallel phase I/II clinical trial design for combination therapies. Biometrics 63:429-436, 2007
    • (2007) Biometrics , vol.63 , pp. 429-436
    • Huang, X.1    Biswas, S.2    Oki, Y.3
  • 17
    • 35348894983 scopus 로고    scopus 로고
    • Adaptive designs for selecting drug combinations based on efficacy-toxicity response
    • Dragalin V, Fedorov VV, Wu Y: Adaptive designs for selecting drug combinations based on efficacy-toxicity response. J Stat Plan Inference 138:352-373, 2008
    • (2008) J Stat Plan Inference , vol.138 , pp. 352-373
    • Dragalin, V.1    Fedorov, V.V.2    Wu, Y.3
  • 18
    • 34248324496 scopus 로고    scopus 로고
    • An adaptive phase I design for identifying a biologically optimal dose for dual agent drug combinations
    • DOI 10.1002/sim.2707
    • Mandrekar SJ, Cui Y, Sargent DJ: An adaptive phase I design for identifying a biologically optimal dose for dual agent drug combinations. Stat Med 26:2317-2330, 2007 (Pubitemid 46730251)
    • (2007) Statistics in Medicine , vol.26 , Issue.11 , pp. 2317-2330
    • Mandrekar, S.J.1    Cui, Y.2    Sargent, D.J.3
  • 19
    • 36248945137 scopus 로고    scopus 로고
    • Recent developments in adaptive designs for phase I/II dose-finding studies
    • DOI 10.1080/10543400701645116, PII 785295976
    • Zohar S, Chevret S: Recent developments in adaptive designs for Phase I/II dose-finding studies. J Biopharm Stat 17:1071-1083, 2007 (Pubitemid 350135835)
    • (2007) Journal of Biopharmaceutical Statistics , vol.17 , Issue.6 , pp. 1071-1083
    • Zohar, S.1    Chevret, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.