Biomarkers of cardiovascular disease are increased in untreated chronic periodontitis: A case control study

Australian Dental Journal

Volumn 59, Issue 1, 2014, Pages 29-36

  Ramirez J H ^a   Parra, B ^a   Gutierrez, S ^a   Arce, R M ^b   Jaramillo, A ^a   Ariza, Y ^a   Contreras, Adolfo ^a  

^a UNIVERSIDAD DEL VALLE   (Colombia)

^b AUGUSTA UNIVERSITY   (United States)

Author keywords

atherosclerosis; cardiovascular; endothelial; inflammation; Periodontal

Indexed keywords

BIOLOGICAL MARKER; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; PEROXIDASE; REACTIVE OXYGEN METABOLITE;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; ATHEROSCLEROSIS; BACTERIUM; BLOOD; CARDIOVASCULAR; CARDIOVASCULAR DISEASE; CASE CONTROL STUDY; CHRONIC PERIODONTITIS; CLINICAL TRIAL; COLOMBIA; ENDOTHELIAL; FEMALE; GINGIVITIS; HUMAN; INFLAMMATION; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; PERIODONTAL; POLYMERASE CHAIN REACTION; RISK FACTOR;

ATHEROSCLEROSIS; CARDIOVASCULAR; ENDOTHELIAL; INFLAMMATION; PERIODONTAL;

ADULT; ANALYSIS OF VARIANCE; BACTERIA; BIOLOGICAL MARKERS; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; CHRONIC PERIODONTITIS; COLOMBIA; E-SELECTIN; FEMALE; GINGIVITIS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; PEROXIDASE; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES; RISK FACTORS;

EID: 84894785284     PISSN: 00450421     EISSN: 18347819     Source Type: Journal    
DOI: 10.1111/adj.12139     Document Type: Article

References (25)

1. Pihlstrom BL, Michalowicz BS, Johnson NW,. Periodontal diseases. Lancet 2005; 366: 1809-1820.
2. Tatakis DN, Kumar PS,. Etiology and pathogenesis of periodontal diseases. Dent Clin North Am 2005; 49: 491-516.
3. Bahekar AA, Singh S, Saha S, Molnar J, Arora R,. The prevalence and incidence of coronary heart disease is significantly increased in periodontitis: a meta-analysis. Am Heart J 2007; 154: 830-837.
4. Higashi Y, Goto C, Jitsuiki D, et al,. Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients. Hypertension 2008; 51: 446-453.
5. Higashi Y, Goto C, Hidaka T, et al,. Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease. Atherosclerosis 2009; 206: 604-610.
6. Tonetti MS, D'Aiuto F, Nibali L, et al,. Treatment of periodontitis and endothelial function. N Engl J Med 2007; 356: 911-920.
7. Moutsopoulos NM, Madianos PN,. Low-grade inflammation in chronic infectious diseases: paradigm of periodontal infections. Ann N Y Acad Sci 2006; 1088: 251-264.
8. Gibson FC 3rd, Hong C, Chou HH, et al,. Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice. Circulation 2004; 109: 2801-2806.
9. Tovar SZE, Franco A, Jácome S, Ruiz J,. III Estudio Nacional en Salud Bucal (ENSAB III). Bogotá: Ministerio de Salud y Centro Nacional de Consultoría CNC, 1999.
10. Armitage GC,. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999; 4: 1-6.
11. Corretti MC, Anderson TJ, Benjamin EJ, et al,. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 2002; 39: 257-265.
12. Slots J,. Rapid identification of important periodontal microorganisms by cultivation. Oral Microbiol Immunol 1986; 1: 48-57.
13. Ashimoto A, Chen C, Bakker I, Slots J,. Polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions. Oral Microbiol Immunol 1996; 11: 266-273.
14. Zakynthinos E, Pappa N,. Inflammatory biomarkers in coronary artery disease. J Cardiol 2009; 53: 317-333.
15. Hernandez M, Gamonal J, Tervahartiala T, et al,. Associations between matrix metalloproteinase-8 and -14 and myeloperoxidase in gingival crevicular fluid from subjects with progressive chronic periodontitis: a longitudinal study. J Periodontol 2010; 81: 1644-1652.
16. Queiroz-Junior CM, Pacheco CM, Fonseca AH, Klein A, Caliari MV, de Francischi JN,. Myeloperoxidase content is a marker of systemic inflammation in a chronic condition: the example given by the periodontal disease in rats. Mediators Inflamm 2009; 2009: 760837.
17. Matthews JB, Wright HJ, Roberts A, Ling-Mountford N, Cooper PR, Chapple IL,. Neutrophil hyper-responsiveness in periodontitis. J Dent Res 2007; 86: 718-722.
18. Botero JE, Contreras A, Lafaurie G, Jaramillo A, Betancourt M, Arce RM,. Occurrence of periodontopathic and superinfecting bacteria in chronic and aggressive periodontitis subjects in a Colombian population. J Periodontol 2007; 78: 696-704.
19. Socransky SS, Haffajee AD,. Dental biofilms: difficult therapeutic targets. Periodontol 2000 2002; 28: 12-55.
20. Amar S, Gokce N, Morgan S, Loukideli M, Van Dyke TE, Vita JA,. Periodontal disease is associated with brachial artery endothelial dysfunction and systemic inflammation. Arterioscler Thromb Vasc Biol 2003; 23: 1245-1249.
21. Elter JR, Hinderliter AL, Offenbacher S, et al,. The effects of periodontal therapy on vascular endothelial function: a pilot trial. Am Heart J 2006; 151: 47.
22. Mercanoglu F, Oflaz H, Oz O, et al,. Endothelial dysfunction in patients with chronic periodontitis and its improvement after initial periodontal therapy. J Periodontol 2004; 75: 1694-1700.
23. Seinost G, Wimmer G, Skerget M, et al,. Periodontal treatment improves endothelial dysfunction in patients with severe periodontitis. Am Heart J 2005; 149: 1050-1054.
24. Blum A, Kryuger K, Mashiach Eizenberg M, et al,. Periodontal care may improve endothelial function. Eur J Intern Med 2007; 18: 295-298.
25. Accini JL, Sotomayor A, Trujillo F, Barrera JG, Bautista L, Lopez-Jaramillo P,. Colombian study to assess the use of noninvasive determination of endothelium-mediated vasodilatation (CANDEV). Normal values and factors associated. Endothelium 2001; 8: 157-166.