Chemopreventive effects of berries and berry components in the rodent esophagus

Berries and Cancer Prevention

Volumn , Issue , 2011, Pages 143-161

  Seguin, Claire M ^a   Wang, Li Shu ^a   Stoner, Gary D ^b  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Berries; Cancer; Chemoprevention; Esophagus; Molecular biomarkers; Rodent

Indexed keywords

EID: 84894762933     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4419-7554-6_8     Document Type: Chapter

References (34)

1. Alibardi L, Toni M (2007) Characterization of keratins and associated proteins involved in the corneification of crocodilian epidermis. Tissue Cell 39:311-323
2. Barch DH, Jacoby RF, Brasitus TA et al (1991) Incidence of Harvey ras oncogene point mutations and their expression in methylbenzylnitrosamine-induced esophageal tumorigenesis. Carcinogenesis 12:2373-2377
3. Carlton PS, Kresty LA, Siglin JC et al (2001) Inhibition of N-nitrosomethylbenzylamine-induced tumorigenesis in the rat esophagus by dietary freeze-dried strawberries. Carcinogenesis 2: 441-446
4. Chen T, Hwang H, Rose ME et al (2006) Chemopreventive properties of black raspberries in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis: down-regulation of COX-2, iNOS and c-Jun. Cancer Res 66:2853-2859
5. Chen T, Rose ME, Hwang H et al (2006) Black raspberries inhibit N-nitrosomethylbenzylamine-induced angiogenesis in rat esophagus parallel to the suppression of COX-2 and iNOS. Carcinogenesis 27:2301-2307
6. Chen T, Stoner GD (2004) Inducible nitric oxide synthase expression in N-nitrosomethylbenzy-lamine (NMBA)-induced rat esophageal tumorigenesis. Mol Carcinog 40:232-240
7. Daniel EM, Krupnick AD, Heur YH et al (1989) Extraction, stability, and quantitation of ellagic acid in various fruits and nuts. J Food Comp Anal 2:338-349
8. DeMeester SR (2009) Epidemiology and biology of esophageal cancer. Gastrointest Cancer Res 3:S2-S5
9. Folkman J (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285:1182-1186
10. Garcia M, Jemal A, Ward EM et al (2007) Global cancer facts and figures 2007. American Cancer Society, Atlanta, GA
11. Gross PM, Zhang X, Zhang R (2006) Wolfberry: nature's bounty of nutrition and health, BookSurge Publishing, http://www.wolfberry.org
12. Hecht SS, Huang C, Stoner GD et al (2006) Identification of cyanidin glycosides as constituents of freeze-dried black raspberries which inhibit anti-benzo(a)pyrene-7, 8-diol-9, 10-epoxide induced NFkB and AP-1 activity. Carcinogenesis 27:1617-1626
13. Huang C, Huang Y, Li J et al (2002) Inhibition of BPDE-induced transactivation of AP-1 and NFkB by black raspberry extracts. Cancer Res 62:6857-6863
14. Kresty LA, Morse MA, Morgan C et al (2001) Chemoprevention of esophageal tumorigenesis by dietary administration of lyophilized black raspberries. Cancer Res 61:6112-6119
15. Kurtz A, Signer A, Cabal-Manzano RH et al (2004) Differential regulation of a fibroblast growth factor-binding protein during skin carcinogenesis and wound healing. Neoplasia 6:595-602
16. Liston BW, Gupta A, Nines R et al (2001) Incidence and effects of Ha-ras codon 12 G-A transition mutations in preneoplastic lesions induced by N-nitrosomethylbenzylamine (NMBA) in the rat esophagus. Mol Carcinog 32:1-8
17. Mandal S, Stoner GD (1990) Inhibition of N-nitrosobenzylmethylamine induced eosphageal tumorigenesis in rats by ellagic acid. Carcinogenesis 11:55-61
18. Namkoong H, Shin SM, Kim HK et al (2006) The bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein. BMC Cancer 6:74
19. Noguchi T, Takeno S, Shibata T et al (2002) VEGF-C expression correlates with histologi-cal differentiation and metastasis in squamous cell carcinoma of the esophagus. Oncol Rep 9:995-999
20. Ribeiro U Jr, Posner MC, Safatle-Ribeiro AV et al (1997) Risk factors for squamous cell carcinoma of the oesophagus. Br J Surg 83:1174-1185
21. Seeram NP (2006) Berries. In: Heber D, Blackburn G, Go V, Milner J (eds) Nutritional oncology. Elsevier, Inc., Amsterdam
22. Stoner GD, Dombkowski AA, Reen RK et al (2008a) Carcinogen-altered genes in rat esophagus positively modulated to normal levels of expression by both black raspberries and phenylethyl isothiocyanate. Cancer Res 68:6460-6467
23. Stoner GD, Gupta A (2001) Etiology and chemoprevention of esophageal squamous cell carcinoma. Carcinogenesis 22:1737-1746
24. Stoner GD, Wang LS, Casto BC (2008b) Laboratory and clinical studies of cancer chemopreven-tion by antioxidants in berries. Carcinogenesis 29:1665-1674
25. Stoner GD, Wang LS, Chen T (2007a) Chemoprevention of esophageal squamous cell carcinoma. Toxicol Appl Pharmacol 224:337-349
26. Stoner GD, Wang LS, Seguin C et al (2010) Multiple berry types prevent N-nitrosomethyl-benzylamine-induced esophageal cancer in rats. Pharm Res 27:1138-1145
27. Stoner GD, Wang LS, Zikri N et al (2007b) Cancer prevention with freeze-dried berries and berry components. Sem Cancer Biol 17:403-410
28. Tanaka H, Kijima H, Tokunaga T et al (1999) Frequent expression of inducible nitric oxide synthase in esophageal squamous cell carcinomas. Int J Oncol 14:1069-1073
29. Wang LS, Dombkowski AA, Rocha C et al (2010a) Effects of black raspberries on late events in N-nitrosomethylbenzylamine-induced rat esophageal carcinogenesis as determined by DNA microarray. Mol Carcinog (in press)
30. Wang LS, Hecht S, Carmella S et al (2009) Anthocyanins in black raspberries prevent esophageal tumors in rats. Cancer Prev Res 2(1):84-93. doi:10.1158/1940-6207.CPAR-08-0155
31. Wang LS, Hecht SS, Carmella SG et al (2010b) Berry ellagitannins may not be sufficient for prevention of tumors in the rodent esophagus. J Agric Food Chem 58:3992-3995
32. Wang Z, Tang L, Sun G et al (2006) Etiological study of esophageal squamous cell carcinoma in an endemic region: a population-based case control study in Huaian, China. BMC Cancer 6:287
33. Xue H, Aziz RM, Sun N et al (2001) Inhibition of cellular transformation by berry extracts. Carcinogenesis 22:351-361
34. Yang W (1992) Exposure level of N-nitrosamines in the gastric juice and its inhibition by vitamin C in high risk areas of esophageal cancer. Chin J Oncol 14:407-410