Treatment of extremely high risk and resistant gestational trophoblastic neoplasia patients in King Chulalongkorn Memorial Hospital

Asian Pacific Journal of Cancer Prevention

Volumn 15, Issue 2, 2014, Pages 925-928

  Oranratanaphan, Shina ^a   Lertkhachonsuk, Ruangsak ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Gestational trophoblastic neoplasia; High risk cases; Recurrence; Salvage treatment

Indexed keywords

ANTINEOPLASTIC AGENT;

ADOLESCENT; ADULT; ARTICLE; CANCER STAGING; DRUG RESISTANCE; FEMALE; FOLLOW UP; HUMAN; MIDDLE AGED; MORTALITY; PATHOLOGY; PREGNANCY; PROGNOSIS; RETROSPECTIVE STUDY; RISK FACTOR; SURVIVAL RATE; TROPHOBLASTIC TUMOR; TUMOR RECURRENCE; YOUNG ADULT;

ADOLESCENT; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; DRUG RESISTANCE, NEOPLASM; FEMALE; FOLLOW-UP STUDIES; GESTATIONAL TROPHOBLASTIC DISEASE; HUMANS; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PREGNANCY; PROGNOSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE; YOUNG ADULT;

EID: 84894675438     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2014.15.2.925     Document Type: Article

References (16)

1. Alazzam M, Tidy J, Osborne R, et al (2012). Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia. Cochrane Database Syst Rev, 12, 8891.
2. Bianconi M, Jankilevich G, Otero S, Nassif J, Storino C (2007). Successful salvage of a relapsed high risk gestational trophoblastic neoplasia patient using capecitabine. Gynecol Oncol, 106, 268-71.
3. Cyriac S, Rajendranath R, Sridevi V, Sagar TG (2011). Etoposide, cisplatin-etoposide, methotrexate, actinomycin-D as primary treatment for management of very-high-risk gestational trophoblastic neoplasia. Int J Gynaecol Obstet, 115, 37-9.
4. Deng L, Zhang J, Wu T, Lawrie TA (2013). Combination chemotherapy for primary treatment of high-risk gestational trophoblastic tumour. Cochrane Database Syst Rev, 1, 5196.
5. Feng F, Xiang Y, Wan X, Geng S, Wang T (2011). Salvage combination chemotherapy with floxuridine, dactinomycin, etoposide, and vincristine (FAEV) for patients with relapsed/chemoresistant gestational trophoblastic neoplasia. Ann Oncol, 22, 1588-94.
6. Hertz R, Li Mc, Spencer Db (1956). Effect of methotrexate therapy upon choriocarcinoma and chorioadenoma. Proc Soc Exp Biol Med, 93, 361-6.
7. Limpongsanurak S, Sitthisomwong T (1999). Metastatic Gestational Trophoblastic Neoplasia at King Chulalongkorn Memorial Hospital. Trophoblast Res, 13, 205-11.
8. Lurain JR, Elfstrand EP (1995). Single-agent methotrexate chemotherapy for the treatment of nonmetastatic gestational trophoblastic tumors. Am J Obstet Gynecol, 172, 574-9.
9. Lurain JR, Singh DK, Schink JC (2010). Management of metastatic high-risk gestational trophoblastic neoplasia: FIGO stages II-IV: risk factor score ≥ 7. J Reprod Med, 55, 199-207.
10. Lurain JR (2011). Gestational trophoblastic disease II: classification and management of gestational trophoblastic neoplasia. Am J Obstet Gynecol, 204, 11-8.
11. Lurain JR, Schink JC (2012). Importance of salvage therapy in the management of high-risk gestational trophoblastic neoplasia. J Reprod Med, 57, 219-24.
12. Osborne R, Dodge J (2012). Gestational trophoblastic neoplasia. Obstet Gynecol Clin North Am, 39, 195-212.
13. Patel SM, Desai A (2010). Management of drug resistant gestational trophoblastic neoplasia. J Reprod Med, 55, 296-300.
14. Roberts JP, Lurain JR (1996). Treatment of low-risk metastatic gestational trophoblastic tumors with single-agent chemotherapy. Am J Obstet Gynecol, 174, 1917-23.
15. Rodriguez N, Goldstein DP, Berkowitz RS (2010). Treating gestational trophoblastic disease. Expert Opin Pharmacother, 11, 3027-39.
16. Wang J, Short D, Sebire NJ, et al (2008). Salvage chemotherapy of relapsed or high-risk gestational trophoblastic neoplasia (GTN) with paclitaxel/cisplatin alternating with paclitaxel/etoposide (TP/TE). Ann Oncol, 19, 1578-83.