Advances and future directions in the targeting of HER2-positive breast cancer: Implications for the future

Current Treatment Options in Oncology

Volumn 15, Issue 1, 2014, Pages 41-54

  Subbiah, Ishwaria M ^a   Gonzalez Angulo, Ana Maria ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

HER2 positive breast cancer; Immunotherapy; Pertuzumab; PI3K signaling; T DM1; Trastuzumab resistance

Indexed keywords

CANCER VACCINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MAYTANSINE; PERTUZUMAB; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SCATTER FACTOR RECEPTOR; TRASTUZUMAB; TRASTUZUMAB EMTANSINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHOSPHORYLATION; BREAST CANCER; CANCER IMMUNOTHERAPY; CANCER STAGING; DIMERIZATION; DISEASE FREE SURVIVAL; DRUG RECEPTOR BINDING; DRUG RESPONSE; DRUG TARGETING; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HER2 GENE; HUMAN; IMMUNOTHERAPY; IN VITRO STUDY; IN VIVO STUDY; LIGAND BINDING; ONCOGENE; PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); RANDOMIZED CONTROLLED TRIAL (TOPIC); REGULATORY MECHANISM; RISK ASSESSMENT; SIGNAL TRANSDUCTION;

ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR TARGETED THERAPY; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN MULTIMERIZATION; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

EID: 84894660263     PISSN: 15272729     EISSN: 15346277     Source Type: Journal    
DOI: 10.1007/s11864-013-0262-4     Document Type: Article

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