DNA persistence after treatment of Lyme borreliosis

Folia Microbiologica

Volumn 59, Issue 2, 2014, Pages 115-125

  Picha D ^a   Moravcova L ^a   Vanousova D ^a   Hercogova J ^a   Blechova Z ^a  

^a UNIVERSITY HOSPITAL BULOVKA   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA;

ARTICLE; BODY FLUID; BORRELIA BURGDORFERI; GENETICS; HUMAN; ISOLATION AND PURIFICATION; LYME DISEASE; MICROBIOLOGY; POLYMERASE CHAIN REACTION; TIME;

BODY FLUIDS; BORRELIA BURGDORFERI GROUP; DNA, BACTERIAL; HUMANS; LYME DISEASE; POLYMERASE CHAIN REACTION; TIME FACTORS;

EID: 84894608376     PISSN: 00155632     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12223-013-0272-4     Document Type: Article

References (32)

1. Aberer E, Bergmann AR, Derler A, Schmidt B (2007) Course of Borrelia burgdorferi DNA shedding in urine after treatment. Acta Derm Venereol 87: 39-42.
2. Bathe CH, Schwartz RA (2011) Lyme disease: part II. Management and prevention. J Am Acad Dermatol 64: 639-653.
3. Bergmann AR, Schmidt BL, Derler AM, Aberer E (2002) Importance of sample preparation for molecular diagnosis of Lyme borreliosis from urine. J Clin Microbiol 40: 4581-4584.
4. Busson A, Reynders M, van den Wijngaert S, Dahma H, Decolvenaer M, Vasseeuer L, Vandenberg O (2012) Evaluation of commercial screening tests and blot assays for the diagnosis of Lyme borreliosis. Diagn Microbiol Infect Dis 73: 246-251.
5. Cabello FC, Godfrey HP, Newman SA (2007) Hidden in plain sight: Borrelia burgdorferi and the extracellular matrix. Trends Microbiol 15: 350-354.
6. Dumler JS (2003) Molecular methods for ehrlichiosis and Lyme disease. Clin Lab Med 23: 867-884.
7. Embers ME, Barthold SW, Borda JT, Bowers L, Doyle L, Hodzic E, Jacobs MB, Hasenkampf NR, Martin DS, Narasimhan S, Phillippi-Falkenstein KM, Purcell JE, Ratterree MS, Philipp MT (2012) Persistence of Borrelia burgdorferi in rhesus macaques following antibiotic treatment of disseminated infection. PLoS One.: e29914. doi: 10. 1371/journal. pone. 0029914.
8. Feder HM Jr, Johnson BJ, O'Connell S, Shapiro ED, Steere AC, Wormser GP, Ad Hoc International Lyme Disease Group, Agger WA, Artsob H, Auwaerter P, Dumler JS, Bakken JS, Bockenstedt LK, Green J, Dattwyler RJ, Munoz J, Nadelman RB, Schwartz I, Draper T, McSweegan E, Halperin JJ, Klempner MS, Krause PJ, Mead P, Morshed M, Porwancher R, Radolf JD, Smith RP Jr, Sood S, Weinstein A, Wong SJ, Zemel L (2007) A critical appraisal of "chronic Lyme disease". N Engl J Med 357: 1422-1430.
9. Hodzic E, Feng S, Holden K, Freet KJ, Barthold SW (2008) Persistence of Borrelia burgdorferi following antibiotic treatment in mice. Antimicrob Agents Chemother 52: 1728-1736.
10. Hulínská D, Votýpka J, Valešová M (1999) Borrelia garinii and Borrelia afzelii in patients with Lyme arthritis. Zentralbl Bakteriol 289: 301-318.
11. Iyer R, Mukherjee P, Wang K, Simons J, Wormser GP, Schwartz I (2012) Detection of Borrelia burgdorferi nucleic acids after antibiotic treatment does not confirm viability. J Clin Microbiol 51(3): 857-62. doi: 10. 1128/JCM. 02785-12.
12. Kaiser R, Lücking CH (1993) Intrathecal synthesis of specific antibodies in neuroborreliosis, comparison of different ELISA techniques and calculation methods. J Neurol Sci 118: 64-72.
13. Lantos PM (2011) Chronic Lyme disease: the controversies and the science. Expert Rev Anti-Infect Ther 9: 787-797.
14. Lebech AM (2002) Polymerase chain reaction in diagnosis of Borrelia burgdorferi infection and studies on taxonomic classification. APMIS 110(Suppl 105): 1-40.
15. Mygland A, Ljostad U, Fingerle V, Rupprecht T, Schmutzhard E, Steiner I (2009) EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis. Eur J Neurol 17: 8-16.
16. Nocton JJ, Dressler F, Rutledge BJ, Rys PN, Persinf DH, Steere AC (1994) Detection of Borrelia burgdorferi DNAby polymerase chain reaction in synovial fluid in Lyme arthritis. N Engl J Med 330: 229-234.
17. Nolte O (2012) Nucleid acid amplification based diagnostic of lyme (neuro-)borreliosis-lost in the jungle of methods, targets, and assays? Open Neurol J 6(Suppl 1-M): 129-139.
18. Pícha D, Moravcová L, Ždárský E, Marešová V, Hulínský V (2005) PCR in Lyme neuroborreliosis: a prospective study. Acta Neurol Scand 112: 287-292.
19. Pícha D, Moravcová L, Holečková D, Ždárský E, Valešová M, Marešová V, Hercogová J, Vaňousová D (2008) Examination of specific DNA by PCR in patients with different forms of Lyme borreliosis. Int J Dermatol 47: 1004-1010.
20. Priem S, Burmester GR, Kamradt T, Wolbart K, Rittig MG, Krause A (1998) Detection of Borrelia burgdorferi by polymerase chain reaction in synovial membrane, but not in synovial fluid from patients with persisting Lyme arthritis after antibiotic therapy. Ann Rheum Dis 57: 118-121.
21. Rauter C, Mueller M, Diterich I, Zeller S, Hassler D, Meergans T, Hartung T (2005) Critical evaluation of urine-based PCR assay for diagnosis of Lyme borreliosis. Clin Diagn Lab Immunol 12: 910-917.
22. Stanek G, Wormser GP, Gray J, Strle F (2012) Lyme borreliosis. Lancet 379: 461-473.
23. Steere AC, Angelis SM (2006) Therapy for Lyme arthritis. Arthritis Rheum 54: 3079-3086.
24. Straubinger RK (2000) PCR-based quantification of Borrelia burgdorferi organisms in canine tissues over a 500-day postinfection period. J Clin Microbiol 38: 2191-2199.
25. Stricker RB (2007) Counterpoint: long-term antibiotic therapy improves persistent symptoms associated with Lyme disease. Clin Infect Dis 45: 149-157.
26. Strle F, Cheng Y, Cimperman J, Maraspin V, Lotric-Furlan S, Nelson JA, Picken MM, Ruzic-Sabljic E, Picken RN (1995) Persistence of Borrelia burgdorferi sensulato in resolved erythema migrans lesions. Clin Infect Dis 21: 380-389.
27. Varde S, Wormser GP, Nowakowski J, Nadelman RB, Bittker S, Cooper D, Schwartz I (1999) Lyme disease: disparity between culture and polymerase chain reaction detection of Borrelia burgdorferi after exposure to ceftriaxone in vitro. Conn Med 63: 589-591.
28. Wilske B, Fingerle V, Schulte-Spechtel U (2007) Microbiological and serological diagnosis of Lyme borreliosis. FEMS Immunol Med Microbiol 49: 13-21.
29. Wormser GP, Shapiro ED (2009) Implications of gender in chronic Lyme disease. J Womens Health 18: 831-834.
30. Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS, Krause PJ, Bakken JS, Strle F, Stanek G, Bockenstedt L, Fish D, Dumler JS, Nadelman RB (2006) The clinical assessment, treatment and prevention of Lyme disease, human granulocytic anaplasmosis and Babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. IDSA Guidelines. Clin Infect Dis. 43: 1089-1134.
31. Wormser GP, Nadelman RB, Schwartz I (2012) The amber theory of Lyme arthritis: initial description and clinical implication. Clin Rheumatol 31: 989-994.
32. Yrjänäinen H, Hytönen J, Hartiala P, Oksi J, Viljanen MK (2010) Persistence of borrelial DNA in the joints of Borrelia burgdorferi-infected mice after ceftriaxone treatment. APMIS 118: 665-673.