Infection-related mortality is higher for kidney allograft recipients with pretransplant diabetes mellitus

Diabetologia

Volumn 57, Issue 3, 2014, Pages 554-561

  Hayer, Manvir K ^a   Farrugia, Daniela ^a   Begaj, Irena ^a   Ray, Daniel ^a   Sharif, Adnan ^a  

^a QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

Cytomegalovirus; Diabetes mellitus; Infection; Kidney allograft; Kidney transplantation; Mortality; Sepsis

Indexed keywords

IMMUNOSUPPRESSIVE AGENT;

ADULT; AGE DISTRIBUTION; ALLOGRAFT; BACTERIAL PNEUMONIA; CAUSE OF DEATH; COMORBIDITY; COMPARATIVE STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; EPIDEMIOLOGY; FEMALE; GRAFT REJECTION; GRAM POSITIVE INFECTION; HERPES VIRUS INFECTION; HUMAN; IMMUNOCOMPROMISED PATIENT; IMMUNOLOGY; KIDNEY TRANSPLANTATION; MALE; MICROBIOLOGY; MIDDLE AGED; MORTALITY; POSTOPERATIVE COMPLICATION; RETROSPECTIVE STUDY; RISK FACTOR; UNITED KINGDOM;

ADULT; AGE DISTRIBUTION; ALLOGRAFTS; CAUSE OF DEATH; COMORBIDITY; DIABETES MELLITUS; DIABETIC NEPHROPATHIES; ENGLAND; FEMALE; GRAFT REJECTION; GRAM-POSITIVE BACTERIAL INFECTIONS; HERPESVIRIDAE INFECTIONS; HUMANS; IMMUNOCOMPROMISED HOST; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; PNEUMONIA, BACTERIAL; POSTOPERATIVE COMPLICATIONS; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84894590818     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3124-5     Document Type: Article

References (37)

1. Rich J, Lee JC (2005) The pathogenesis of Staphylococcus aureus infection in the diabetic NOD mouse. Diabetes 54:2904-2910
2. Hirsch T, Spielmann M, Zuhaili B et al (2008) Enhanced susceptibility to infections in a diabetic wound healing model. BMC Surg 8:2482-2485
3. Rees DA, Alcolado JC (2005) Animal models of diabetes mellitus. Diabet Med 22:359-370
4. Bach JF (2005) Infections and autoimmune diseases. J Autoimmun 25:74-80
5. Joshi N, Caputo GM, Weitekamp MR, Karchmer AW (1999) Infections in patients with diabetes mellitus. N Engl J Med 341:1906-1912
6. Muller LM, Gorter KJ, Hak E, Goudzwaard WL et al (2005) Increased risk of common infections in patients with type 1 and type 2 diabetes mellitus. Clin Infect Dis 41:281-288
7. Peleg AY, Weerarathna T, McCarthy JS, Davis TM (2007) Common infections in diabetes: pathogenesis, management and relationship to glycaemic control. Diabetes Metab Res Rev 23:3-13
8. Bertoni AG, Saydah S, Brancati FL (2001) Diabetes and the risk of infection-related mortality in the U.S. Diabetes Care 24(6):1044-1049
9. Gu K, Cowie CC, Harris MI (1998) Mortality in adults with and without diabetes in a national cohort of the U.S. population, 1971-1993. Diabetes Care 21:1138-1145
10. Moss SE, Klien R, Klein BEK (1991) Cause-specific mortality in a population-based study of diabetes. Am J Public Health 81:1158-1162
11. US Renal Data System (2012) USRDS 2011 annual data report: atlas of chronic kidney disease and end-stage renal disease in the United States. Am J Kidney Dis 59(Suppl 1):e1-e420
12. Briggs JD (2001) Causes of death after renal transplantation. Nephrol Dial Transplant 16:1545-1549
13. Koh GC, Peacock SJ, van der Poll T, Wiersinga WJ (2012) The impact of diabetes on the pathogenesis of sepsis. Eur J Clin Microbiol Infect Dis 31:379-388
14. Kato S, Chmielewski M, Honda H et al (2008) Aspects of immune dysfunction in end-stage renal disease. Clin J Am Soc Nephrol 3:1526-1533
15. Lansang MC, Ma L, Schold JD, Meier-Kriesche HU, Kaplan B (2006) The relationship between diabetes and infectious hospitalizations in renal transplant recipients. Diabetes Care 29:1659-1660
16. OPCS-4 classification - NHS Connecting for Health. Available from www.connectingforhealth.nhs.uk. Accessed 12 June 2013
17. World Health Organization: International Classification of Diseases (ICD). Available from www.who.int/classifications/icd/en. Accessed 5 June 2013
18. Department for Communities and Local Government. The English Indices of Deprivation 2010. Available from www.gov.uk/government/publications/english- indices-of-deprivation-2010. Accessed17 June 2013
19. von Elm E, Altman DG, Egger M et al (2007) The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 370(9596):1453-1457
20. Steenkamp R, Shaw C, Feest T (2013) UK Renal Registry 15th Annual Report: Chapter 5, Survival and causes of death of UK adult patients on renal replacement therapy in 2011: national and centre-specific analyses. Nephron Clin Pract 123(Suppl 1):93-123
21. Zykova SN, Jenssen TG, Berdal M et al (2000) Altered cytokine and nitric oxide secretion in vitro by macrophages from diabetic type II-like db/db mice. Diabetes 49:1451-1458
22. Al-Mashat HA, Kandru S, Liu R et al (2006) Diabetes enhances mRNA levels of proapoptotic genes and caspase activity, which contribute to impaired healing. Diabetes 55:487-495
23. Ilyas R, Wallis R, Soilleux EJ et al (2011) High glucose disrupts oligosaccharide recognition function via competitive inhibition: a potential mechanism for immune dysregulation in diabetes mellitus. Immunobiology 216:126-131
24. Price CL, Hassi HO, English NR et al (2010) Methylglyoxal modulates immune responses: relevance to diabetes. J Cell Mol Med 14:1806-1815
25. Benfield T, Jensen JS, Nordestgaard BG (2007) Influence of diabetes and hyperglycaemia on infectious disease hospitalisation and outcome. Diabetologia 50:549-554
26. Marelli D, Laks H, Patel B et al (2003) Heart transplantation in patients with diabetes mellitus in the current era. J Heart Lung Transplant 22:1091-1097
27. Thomas MC, Mathew TH, Russ GR et al (2001) Early peri-operative glycaemic control and allograft rejection in patients with diabetes mellitus: a pilot study. Transplantation 72:1321-1324
28. Kotton CN, Fishman JA (2005) Viral infection in the renal transplant recipient. J Am Soc Nephrol 16:1758-1774
29. Yoon JW (1990) The role of viruses and environmental factors in the induction of diabetes. Curr Top Microbiol Immunol 164:95-123
30. Pak CY, McArthur RG, Eun HM, Yoon JW (1988) Association of cytomegalovirus infection with autoimmune type 1 diabetes. Lancet 332:1-4
31. Hjelmesaeth J, Muller F, Jenssen T, Rollag H, Sagedal S, Hartmann A (2005) Is there a link between cytomegalovirus infection and new-onset diabetes after transplantation? Potential mechanisms of virus induced beta-cell damage. Nephrol Dial Transplant 20:2311-2315
32. Leung Ki EL, Venetz JP, Meylan P, Lamoth F, Ruiz J, Pascual M (2008) Cytomegalovirus infection and new-onset diabetes after transplantation. Clin Transplant 22:245-249
33. Sharif A, Baboolal K (2011) Complications of new onset diabetes after kidney transplantation. Nat Rev Nephrol 8:34-42
34. Benavides FG, Bolumar F, Peris R (1989) Quality of death certificates in Valencia, Spain. Am J Public Health 79:1352-1354
35. Pinner R, Tetutsh SM, Simonsen L et al (1996) Trends in infectious disease mortality in the United States. JAMA 275:189-193
36. Kircher T, Nelson J, Burdo H (1985) The autopsy as a measure of accuracy of the death certificate. N Engl J Med 313:1263-1269
37. Lloyd-Jones DM, Martin DO, Larson MG, Levy D (1998) Accuracy of death certificates for coding coronary heart disease as the cause of death. Ann Intern Med 129:1020-1026