Plasma coenzyme Q10 levels in type 2 diabetic patients with retinopathy

International Journal of Ophthalmology

Volumn 6, Issue 5, 2013, Pages 675-679

  Ates, Orhan ^a   Bilen, Habip ^b   Keles, Sadullah ^a   Hakan Alp, H ^a   Keleş, Mevlüt Sait ^a   Yildirim, Kenan ^a   Öndas, Osman ^a   Can Pinar, L ^a   Civelekler, Mustafa ^c   Baykal, Orhan ^a  

^a ATATURK UNIVERSITY   (Turkey)

^b ATATÜRK UNIVERSITY   (Turkey)

^c Etimesgut Military Hospital   (Turkey)

Author keywords

Coenzyme Q10; Diabetic; Retinopathy

Indexed keywords

EID: 84894538765     PISSN: 22223959     EISSN: 22274898     Source Type: Journal    
DOI: 10.3980/j.issn.2222-3959.2013.05.24     Document Type: Article

References (34)

1. Son SM. Reactive oxygen and nitrogen species in pathogenesis of vascular complications of diabetes. Diabetes Metab J. 2012;36(3):190-198.
2. Antonetti DA, Klein R, Gardner TW. Diabetic retinopathy. N Engl J Med. 2012;366(13):1227-1239.
3. Crawford TN, Alfaro DV, Kerrison JB, Jablon EP. Diabetic retinopathy and angiogenesis. Curr Diabetes Rev. 2009;5(1):8-13.
4. Gündüz K, Bakri SJ. Management of proliferative diabetic retinopathy. Compr Ophthalmol Update. 2007;8(5):245-256.
5. Ishibashi T. Cell biology of intraocular vascular diseases. Nihon Ganka Gakkai Zasshi. 1999;103(12):923-947.
6. Trudeau K, Molina A J, Roy S. High glucose induces mitochondrial morphology and metabolic changes in retinal pericytes. Invest Ophthalmol. Vis Sci. 2011;52(12):8657-8664.
7. El-Asrar A M. Role of inflammation in the pathogenesis of diabetic retinopathy. Middle East Afr J Ophthalmol. 2012;19(1):70-74.
8. Arden GB, Sivaprasad S. Hypoxia and oxidative stress in the causation of diabetic retinopathy. Curr Diabetes Rev. 2011;7(5):291-304.
9. Kasznicki J, Kosmalski M, Sliwinska A, Mrowicka M, Stanczyk M, Majsterek I, Drzewoski J. Evaluation of oxidative stress markers in pathogenesis of diabetic neuropathy. Mol Biol Rep. 2012;39(9):8669-8678.
10. Sahnoun Z, Jamoussi K, Zeghal KM. Free radicals and antioxidants: physiology, human pathology and therapeutic aspects (part II) Therapie. 1998;53(4):315-339.
11. Raffaele M, Donato DP, Chiara V, Angelica C, Alessandra F, Claudio C, Maria Dolores P D, Massimiliano C, Carlo N. Lipid peroxidation and total antioxidant capacity in vitreous, aqueou s humor, and blood samples from patients with diabetic retinopathy. Mol Vis. 2011;17:1298-1304.
12. Miranda M, Muriach M, Roma J, Bosch-Morell F, Genovés JM, Barcia J, Araiz J, Díaz-Llospis M, Romero FJ. Oxidative stress in a model of experimental diabetic retinopathy: the utility of peroxinytrite scavengers. Arch Soc Esp Oftalmol. 2006;81(1):27-32.
13. Santos JM, Tewari S, Goldberg A F, Kowluru RA. Mitochondrial biogenesis and the development of diabetic retinopathy. Free Radic Biol Med. 2011;51(10):1849-1860.
14. Kanwar M, Chan PS, Kern TS, Kowluru RA. Oxidative damage in the retinal mitochondria of diabetic mice: possible protection by superoxide dismutase. Invest Ophthalmol Vis Sci. 2007;48(8):3805-3811.
15. Ostman B, Sjödin A, Michaëlsson K, Byberg L. Coenzyme Q1 0 supplementation and exercise-induced oxidative stress in humans. Nutrition. 2012;28(4):403-417.
16. Littaru GP, Langsjoen P. Coensyme Q10 and statins: biochemical and clinical implications. Mitochondrion. 2007;7:S168-174.
17. Chinnery P, Majamaa K, Turnbull D, Thorburn D. Treatment for mitochondrial disorders. Cochrane Database Syst Rev. 2006;25(1): CD004426.
18. Ernster L, Dallner G. Biochemical, physiogical and medical aspects of ubiquinone function. Biochim Biophys Acta. 1995;271(1):195-204.
19. Stocker R, Bowry VW, Frei B. Ubiquinol-10 protects human l ow density lipoprotein more efficiently against lipid peroxidation than does al-pha-tocopherol. Proc Natl Acad Sci. 1991;88(5):1646-1650.
20. Yamashita S, Yamamoto Y. Simultaneous detection of ubiquinol and ubiquinone in human plasma as a marker of oxidative stress. Anal Biochem. 1997;250(1):66-73.
21. Giannubilo SR, Tiano L, Cecchi S, Principi F, Tranquilli AL, Littarru GP. Plasma coenzyme Q10 is increased during gestational diabetes. DiabetesRes Clin Pract. 2011;94(2):230-235.
22. Early Treatment Diabetic Retinopathy Study Research Group Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Ophthalmology. 1991;98(5 Suppl):823-833.
23. Mosca F, Fattorini D, Bompadre S, Littarru GP. Assay of coenzyme Q (10) in plasma by a single dilution step. Anal Biochem. 2002;305(1):49-54.
24. Tomasetti M, Alleva R, Solenghi MD, Littarru GP. Distribution of antioxidants among blood components and lipoproteins: significance of li-pids/CoQ10 ratio as a possible marker of increased risk for atherosclerosis. Biofactors. 1999;9(2-4):231-240.
25. Mateos R, Lecumberri E, Ramos S, Goya L, Bravo L. Determination of malondialdehyde (MDA) by high-performance liquid chromatography in serum and liver as a biomarker for oxidative stress. Application to a rat model for hypercholesterolemia and evaluation of the effect of diets rich in phenolic antioxidants from fruits. Chromatogr B Analyt Technol Biomed Life Sci. 2005;827(1):76-82.
26. Soliman GZ. Blood lipid peroxidation (superoxide dismutase, malondialdehyde, glutathione) levels in Egyptian type 2 diabetic patients. Singapore Med J. 2008;49(2):129-136.
27. Kesavulu MM, Giri R, Kameswara Rao B, Apparao C. Lipid peroxidation and antioxidant enzyme levels in type 2 diabetics with microvascular complications. Diabetes Metab. 2000;26(5):387-392.
28. Mahboob M, Rahman MF, Grover P. Serum lipid peroxidation and antioxidant enzyme levels in male and female diabetic patients. Singapore Med J. 2005;46(7):322-324.
29. Palanduz S, Ademoǧlu E, Gökkusu C, Tamer S. Plasma antioxidants and type 2 diabetes mellitus. Res Commun Mol Pathol Pharmacol. 2001;109(5-6):309-318.
30. El-ghoroury EA, Raslan HM, Badawy EA, El-Saaid GS, Agybi MH, Siam I, Salem SI. Malondialdehyde and coenzyme Q10 in platelets and serum in type 2 diabetes mellitus: correlation with glycemic control. Blood Coagul Fibrinolysis. 2009;20(4):248-251.
31. Lim SC, Tan HH, Goh SK, Sunramaniam T, Sum CF, Tan IK, Lee BL, Ong CN. (Oxidative burden in prediabtic and diabetic individuals: evidence of plasma Coenzyme Q10. Diabet Med. 2006;23(12):1344-1349.
32. Zhang Y, Aberg F, Appelkvist EL, Dallner G, Ernster L. Uptake of dietary coenzyme Q supplement is limited in rat. J Nutr. 1995;125(3):446-453.
33. Menke T, Niklowitz P, Wiesel T, Andler W. Antioxidant level and redox status of coenzyme Q10 in the plasma and blood cells of children with diabetes mellitus type 1. Pediatr Diabetes. 2008;9(6):540-545.
34. Sourris KC, Harcourt BE, Tang PH, Morley AL, Huynh K, Penfold SA, Coughlan MT, Cooper ME, Nguyen TV, Ritchie RH, Forbes JM. Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes. Free Radic Biol Med. 2012;52(3):716-723.