Predictors of visual outcome in eyes with choroidal neovascularization secondary to age related macular degeneration treated with intravitreal bevacizumab monotherapy

International Journal of Ophthalmology

Volumn 6, Issue 1, 2013, Pages 62-66

  Chhablani, Jay ^a,b   Kim, Jae Suk ^a,c   Freeman, William R ^a   Kozak, Igor ^a   Wang, Hai Yan ^a   Cheng, Lingyun ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b L V PRASAD EYE INSTITUTE   (India)

^c Inje University College of Medicine   (South Korea)

Author keywords

Age related macular degeneration; Avastin; Choroidal neov ascularization; External limiting membrane

Indexed keywords

EID: 84894522228     PISSN: 22223959     EISSN: 22274898     Source Type: Journal    
DOI: 10.3980/j.issn.2222-3959.2013.01.13     Document Type: Article

References (24)

1. Pascolini D, Mariotti SP, Pokharel GP, Pararajasegaram R., Etya'ale D, Negrel AD, Resnikoff S. 2002 global update of available data on visual impairment: a compilation of population-based prevalence studies. Ophthalmic Epidemiol. 2004;11(2):67-115.
2. Resnikoff S, Pascolini D, Etya'ale D, Kocur I, Pararajasegaram R, Pokharel GP, Mariotti SP. Global data on visual impairment in the year 2002. Bull World Health Organ. 2004;82(11):844-851.
3. Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials - TAP report. Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group. Arch Ophthalmol. 1999;117(10):1329-1345.
4. Ozkiris A. Anti-VEGF agents for age-related macular degeneration. Expert Opin Ther Pat. 2010;20(1):103-118.
5. Mousa SA, Mousa SS Current status of vascular endothelial growth factor inhibition in age-related macular degeneration. BioDrugs. 2010;24(3):183-194.
6. Doris N, Hart PM, Chakravarthy U, McCleland J., Stevenson M, Hudson C, Jackson J. Relation between macular morphology and visual function in patients with choroidal neovascularisation of age related macular degeneration. Br J Ophthalmol. 2001;85(2):184-188.
7. Keane PA, Liakopoulos S, Chang KT, Wang M., Dustin L, Walsh AC, Sadda SR Relationship between optical coherence tomography retinal parameters and visual acuity in neovascular age-related macular degeneration. Ophthalmology. 2008;115(12):2206-2214.
8. Moutray T, Alarbi M, Mahon G., Stevenson M, Chakravarthy U. Relationships between clinical measures of visual function, fluorescein angiographic and optical coherence tomography features in patients with subfoveal choroidal neovascularisation. Br J Ophthalmol. 2008;92(3):361-364.
9. Unver YB, Yavuz GA, Bekiroglu N, Presti P., Li W, Sinclair SH Relationships between clinical measures of visual function and anatomic changes associated with bevacizumab treatment for choroidal neovascularization in age-related macular degeneration. Eye (Lond) 2009;23(2):453-460.
10. Wakabayashi T, Oshima Y, Fujimoto H., Murakami Y, Sakaguchi H, Kusaka S., Tano Y. Foveal microstructure and visual acuity after retinal detachment repair: imaging analysis by Fourier-domain optical coherence tomography. Ophthalmology. 2009;116(3):519-528.
11. Wakabayashi T, Fujiwara M, Sakaguchi H., Kusaka S, Oshima Y. Foveal microstructure and visual acuity in surgically closed macular holes: spectral-domain optical coherence tomographic analysis. Ophthalmology. 2010;117(9):1815-1824.
12. Murakami T, Nishijima K, Sakamoto A., Ota M, Horii T, Yoshimura N. Association of pathomorphology, photoreceptor status, and retinal thickness with visual acuity in diabetic retinopathy. Am J Ophthalmol. 2011;151(2):310-317.
13. Maheshwary AS, Oster SF, Yuson RM, Cheng L., Mojana F, Freeman WR The association between percent disruption of the photoreceptor inner segment-outer segment junction and visual acuity in diabetic macular edema. Am J Ophthalmol. 2010;150(1):63-67.
14. Li D, Kishi S. Loss of photoreceptor outer segment in acute zonal occult outer retinopathy. Arch Ophthalmol. 2007;125(9):1194-1200.
15. Oishi A, Hata M, Shimozono M., Mandai M, Nishida A, Kurimoto Y. The significance of external limiting membrane status for visual acuity in age-related macular degeneration. Am J Ophthalmol. 2010;150(1):27-32.
16. Shin HJ, Chung H, Kim HC Association between foveal microstructure and visual outcome in age-related macular degeneration. Retina. 2011;31(8):1627- 1636.
17. Kang S, Roh YJ One-year results of intravitreal ranibizumab for neovascular age-related macular degeneration and clinical responses of various subgroups. Jpn J Ophthalmol. 2009;53(4):389-395.
18. Levy J, Shneck M, Rosen S., Klemperer I, Rand D, Weinstein O., Pitchkhadze A, Belfair N, Lifshitz T. Intravitreal bevacizumab (avastin) for subfoveal neovascular age-related macular degeneration. Int Ophthalmol. 2009;29(5):349-357.
19. Spaide RF, Laud K, Fine HF, Klancnik JM, Jr, Meyerle CB, Yannuzzi LA, Sorenson J, Slakter J, Fisher YL, Cooney MJ. Intravitreal bevacizumab treatment of choroidal neovascularization secondary to age-related macular degeneration. Retina. 2006;26(4):383-390.
20. Piccolino FC, de la Longrais RR, Ravera G, Eandi CM, Ventre L, Abdollahi A, Manea M. The foveal photoreceptor layer and visual acuity loss in central serous chorioretinopathy. Am J Ophthalmol. 2005;139(1):87-99.
21. Hayashi H, Yamashiro K, Tsujikawa A., Ota M, Otani A, Yoshimura N. Association between foveal photoreceptor integrity and visual outcome in neovascular age-related macular degeneration. Am J Ophthalmol. 2009;148(1):83-89.
22. Bunt-Milam AH, Saari JC, Klock IB, Garwin GG Zonulae adherentes pore size in the external limiting membrane of the rabbit retina. Invest Ophthalmol Vis Sci. 1985;26(10):1377-1380.
23. Theodossiadis PG, Grigoropoulos VG, Theodossiadis GP The significance of the external limiting membrane in the recovery of photoreceptor layer after successful macular hole closure: a study by spectral domain optical coherence tomography. Ophthalmologica. 2011;225(3):176-184.
24. Dimitrov PN, Robman LD, Varsamidis M, Aung KZ, Makeyeva GA, Guymer RH, Vingrys AJ Visual function tests as potential biomarkers in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2011;52(13):9457-9469.