Phenotypic Characterization and In Vivo Localization of Human Adipose-Derived Mesenchymal Stem Cells

Molecules and Cells

Volumn 35, Issue 6, 2013, Pages 557-564

  Ryu, Young Joon ^c   Cho, Tae Jun ^a,b   Lee, Dong Sup ^d   Choi, Jin Young ^b   Cho, Jaejin ^a,b  

^a Department of Dental Regenerative Biotechnology ^*

^b BK 21 Plus   (South Korea)

^c Kangwon National University College of Medicine   (South Korea)

^d Seoul National University College of Medicine   (South Korea)

Author keywords

adipose tissue; immunohistochemistry; in situ localization; mesenchymal stem cells; ultrastructure

Indexed keywords

BIOLOGICAL MARKER; MEMBRANE METALLOENDOPEPTIDASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR;

ADIPOSE TISSUE; ADVENTITIA; AUTOTRANSPLANTATION; CELL CULTURE; CYTOLOGY; HUMAN; IMMUNOPHENOTYPING; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; METABOLISM; NUCLEOLUS; PHYSIOLOGY; PROCEDURES; PSEUDOPODIUM; STEM CELL NICHE; TISSUE REGENERATION; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ADIPOSE TISSUE; ADVENTITIA; BIOLOGICAL MARKERS; CELL NUCLEOLUS; CELLS, CULTURED; GUIDED TISSUE REGENERATION; HUMANS; IMMUNOPHENOTYPING; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICROSCOPY, ELECTRON, TRANSMISSION; NEPRILYSIN; PSEUDOPODIA; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; STEM CELL NICHE; TRANSPLANTATION, AUTOLOGOUS;

EID: 84894500563     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-013-0112-z     Document Type: Article

References (40)

1. Allt, G., Lawrenson, J.G., Pericytes: cell biology and pathology. Cells Tissues Organs, 169, 2001, 1–11.
2. Armulik, A., Abramsson, A., Betsholtz, C., Endotheli- al/pericyte interactions. Circ. Res., 97, 2005, 512–523.
3. Ball, S.G., Shuttleworth, C.A., Kielty, C.M., Platelet- derived growth factor receptors regulate mesenchymal stem cell fate: implications for neovascularization. Exp. Opin. Biol. Ther. 10 (2010), 57–71.
4. Caplan, A.I., All MSCs are pericytes? Cell Stem Cell., 11, 2008, 229–230.
5. Cho, T.-J., Kim, J., Kwon, S.-K., Oh, K., Lee, J.-A., Lee, D.-S., Cho, J., Park, S., A potent small-molecule inducer of chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells. Chem. Sci., 3, 2012 3071-3071.
6. Crisan, M., Yap, S., Casteilla, L., Chen, C.W., Corselli, M., Park, T.S., Andriolo, G., Sun, B., Zheng, B., Zhang, L., et al. A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell, 3, 2008, 301–313.
7. Deslex, S., Negrel, R., Vannier, C., Etienne, J., Ailhaud, G., Differentiation of human adipocyte precursors in a chemically defined serum-free medium. Int. J. Obes. 11 (1987), 19–27.
8. Dore-Duffy, P., Cleary, K., Morphology and properties of pericytes. Methods Mol. Biol., 686, 2011, 49–68.
9. Gimble, J.M., Katz, A.J., Bunnell, B.A., Adipose-derived stem cells for regenerative medicine. Circ. Res., 100, 2007, 1249–1260.
10. Gronthos, S., Franklin, D.M., Leddy, H.A., Robey, P.G., Storms, R.W., Gimble, J.M., Surface protein characterization of human adipose tissue-derived stromal cells. J. Cell. Physiol., 189, 2001, 54–63.
11. Hauner, H., Schmid, P., Pfeiffer, E.F., Glucocorticoids and insulin promote the differentiation of human adipocyte precursor cells into fat cells. J. Clin. Endocrinol. Metab., 64, 1987, 832–835.
12. Klein, D., Hohn, H.P., Kleff, V., Tilki, D., Ergün, S., Vascular wall-resident stem cells. Histol. Histopathol., 25, 2010, 681–689.
13. Krenacs, T., Zsakovics, I., Diczhazi, C., Ficsor, L., Varga, V.S., Molnar, B., The potential of digital microscopy in breast pathology. Pathol. Oncol. Res., 15, 2009, 55–58.
14. Musina, R.A., Bekchanova, E.S., Sukhikh, G.T., Comparison of mesenchymal stem cells obtained from different human tissues. Bull. Exp. Biol. Med., 139, 2005, 504–509.
15. Lin, G., Garcia, M., Ning, H., Banie, L., Guo, Y.L., Lue, T.F., Lin, C.S., Defining stem and progenitor cells within adipose tissue. Stem Cells Dev. 17 (2008), 1053–1063.
16. Lin, C.S., Xin, Z.C., Deng, C.H., Ning, H., Lin, G., Lue, T.F., Defining adipose tissue-derived stem cells in tissue and in culture. Histol. Histopathol., 25, 2010, 807–815.
17. Locke, M., Feisst, V., Dunbar, P.R., Concise review: human adipose-derived stem cells: separating promise from clinical need. Stem Cells, 29, 2011, 404–411.
18. Majesky, M.W., Dong, X.R., Hoglund, V., Mahoney, W.M. Jr., Daum, G., The adventitia: a dynamic interface containing resident progenitor cells. Arterioscler. Thromb. Vasc. Biol. 31 (2011), 1530–1539.
19. Majesky, M.W., Dong, X.R., Regan, J.N., Hoglund, V.J., Vascular smooth muscle progenitor cells: building and repairing blood vessels. Circ. Res., 108, 2011, 365–377.
20. Mariotti, E., Mirabelli, P., Abate, G., Schiattarella, M., Martinelli, P., Fortunato, G., Di Noto, R., Del Vecchio, L., Comparative characteristics of mesenchymal stem cells from human bone marrow and placenta: CD10, CD49d, and CD56 make a difference. Stem Cells Dev., 17, 2008, 1039–1041.
21. McIntosh, K., Zvonic, S., Garrett, S., Mitchell, J.B., Floyd, Z.E., Hammill, L., Kloster, A., Di Halvorsen, Y., Ting, J.P., Storms, R.W., et al. The immunogenicity of human adipose-derived cells: temporal changes in vitro. Stem Cells, 24, 2006, 1246–1253.
22. Mitchell, J.B., McIntosh, K., Zvonic, S., Garrett, S., Floyd, Z.E., Kloster, A., Di Halvorsen, Y., Storms, R.W., Goh, B., Kilroy, G., et al. Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers. Stem Cells 24 (2006), 376–385.
23. Musina, R.A., Bekchanova, E.S., Sukhikh, G.T., Comparison of mesenchymal stem cells obtained from different human tissues. Bull. Exp. Biol. Med., 139, 2005, 504–509.
24. Nakagami, H., Morishita, R., Maeda, K., Kikuchi, Y., Ogihara, T., Kaneda, Y., Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy. J. Atheroscler. Thromb., 13, 2006, 77–81.
25. Ning, H., Lin, G., Lue, T.F., Lin, C.S., Neuron-like differentiation of adipose tissue-derived stromal cells and vascular smooth muscle cells. Differentiation, 74, 2006, 510–518.
26. Pacilli, A., Pasquinelli, G., Vascular wall resident progenitor cells: a review. Exp. Cell Res. 315 (2009), 901–914.
27. Papanicolaou, G.N., A new procedure for staining vaginal smears. Science 95 (1942), 438–439.
28. Pasquinelli, G., Tazzari, P., Ricci, F., Vaselli, C., Buzzi, M., Conte, R., Orrico, C., Foroni, L., Stella, A., Alviano, F., et al. Ultrastructural characteristics of human mesenchymal stromal (stem) cells derived from bone marrow and term placenta. Ultra- struct. Pathol., 31, 2007, 23–31.
29. Pettersson, P., Cigolini, M., Sjöström, L., Smith, U., Björntorp, P., Cells in human adipose tissue developing into adipocytes. Acta Med. Scand., 215, 1984, 447–451.
30. Psaltis, P.J., Zannettino, A.C., Worthley, S.G., Gronthos, S., Concise review: mesenchymal stromal cells: potential for cardiovascular repair. Stem Cells, 26, 2008, 2201–2210.
31. Rodbell, M., Jones, A.B., Chiappe de Cingolani, G.E., Birn- baumer, L., The actions of insulin and catabolic hormones on the plasma membrane of the fat cells. Recent Prog. Horm. Res. 24 (1968), 215–254.
32. Schäffler, A., Büchler, C., Concise review: adipose tissue-derived stromal cells–basic and clinical implications for novel cell-based therapies. Stem Cells., 25, 2007, 818–827.
33. Sims, D.E., The pericyte-a review. Tissue Cell, 18, 1986, 153–174.
34. Tholpady, S.S., Llull, R., Ogle, R.C., Rubin, J.P., Futrell, J.W., Katz, A.J., Adipose tissue: stem cells and beyond. Clin. Plast Surg., 33, 2006, 55–62.
35. Traktuev, D.O., Merfeld-Clauss, S., Li, J., Kolonin, M., Arap, W., Pasqualini, R., Johnstone, B.H., March, K.L., A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks. Circ. Res., 102, 2008, 77–85.
36. Vandenabeele, F., De Bari, C., Moreels, M., Lambrichts, I., Dell'Accio, F., Lippens, P.L., Luyten, F.P., Morphological and immunocytochemical characterization of cultured fibroblast-like cells derived from adult human synovial membrane. Arch. Histol. Cytol., 66, 2003, 145–153.
37. Wilson, A., Butler, P.E., Seifalian, A.M., Adipose-derived stem cells for clinical applications: a review. Cell Prolif. 44 (2011), 86–98.
38. Zengin, E., Chalajour, F., Gehling, U.M., Ito, W.D., Treede, H., Lauke, H., Weil, J., Reichenspurner, H., Kilic, N., Ergün, S., Vascular wall resident progenitor cells: a source for postnatal vasculogenesis. Development, 133, 2006, 1543–1551.
39. Zimmerlin, L., Donnenberg, V.S., Pfeifer, M.E., Meyer, E.M., Péault, B., Rubin, J.P., Donnenberg, A.D., Stromal vascular progenitors in adult human adipose tissue. Cytometry A, 77, 2010, 2230.
40. Zuk, P.A., Zhu, M., Mizuno, H., Huang, J., Futrell, J.W., Katz, A.J., Benhaim, P., Lorenz, H.P., Hedrick, M.H., Multilineage cells from human adipose tissue: implications for cellbased therapies. Tissue Eng., 7, 2001, 211–228.