Lack of association of EPHX1 gene polymorphisms with risk of hepatocellular carcinoma: A meta-analysis

Tumor Biology

Volumn 35, Issue 1, 2014, Pages 659-666

  Duan, Chen Yang ^a   Liu, Meng Ying ^b   Li, Shao Bo ^b   Ma, Kuan Sheng ^b   Bie, Ping ^b  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Hepatocellular carcinoma; Meta analysis; Microsomal epoxide hydrolase

Indexed keywords

ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; DNA POLYMORPHISM; EPHX1 GENE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC MODEL; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LIVER CELL CARCINOMA; PRIORITY JOURNAL; SENSITIVITY ANALYSIS;

ALLELES; CARCINOMA, HEPATOCELLULAR; CASE-CONTROL STUDIES; EPOXIDE HYDROLASES; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LIVER NEOPLASMS; ODDS RATIO; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PUBLICATION BIAS; RISK;

EID: 84894475988     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-1090-7     Document Type: Article

References (21)

1. El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology. 2007;132:2557-76.
2. El-Serag HB. Hepatocellular carcinoma. N Engl J Med. 2011;365: 1118-27.
3. Coleman WB. Mechanisms of human hepatocarcinogenesis. Curr Mol Med. 2003;3:573-88.
4. McGlynn KA, Rosvold EA, Lustbader ED, Hu Y, ClapperML, et al. Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1. Proc Natl Acad Sci U S A. 1995;92:2384-7.
5. Shen F, Hu Y. Association between the gene polymorphism of epoxide hydrolase and the susceptibility to primary hepatocellular carcinoma. Chin J Med Genet. 1997;14:96-8.
6. Wong NA, Rae F, Bathgate A, Smith CA, Harrison DJ. Polymorphisms of the gene for microsomal epoxide hydrolase and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a Caucasian population. Toxicol Lett. 2000;115:17-22.
7. Tiemersma EW, Omer RE, Bunschoten A, van't Veer P, Kok FJ, et al. Role of genetic polymorphism of glutathione-S-transferase T1 and microsomal epoxide hydrolase in aflatoxin-associated hepatocellular carcinoma. Cancer Epidemiol Biomarkers Prev. 2001; 10:785-91.
8. Sonzogni L, Silvestri L, De Silvestri A, Gritti C, Foti L, et al. Polymorphisms of microsomal epoxide hydrolase gene and severity of HCV related liver disease. Hepatology. 2002;36:195-201.
9. McGlynn KA, Hunter K, LeVoyer T, Roush J,Wise P, et al. Susceptibility to aflatoxin B1-related primary hepatocellular carcinoma in mice and humans. Cancer Res. 2003;63:4594-601.
10. Cao YY, Bian JC, Jiang F, Zhang ZM, Wang QM, et al. Association between the genetic polymorphism of epoxide hydrolase and the genetic susceptibility to primary liver cancer. Fudan Univ J Med Sci. 2004;31:363-7.
11. Kirk GD, Turner PC, Gong Y, Lesi OA, Mendy M, et al. Hepatocellular carcinoma and polymorphisms in carcinogen-metabolizing and DNA repair enzymes in a population with aflatoxin exposure and hepatitis B virus endemicity. Cancer Epidemiol Biomarkers Prev. 2005;14:373-9.
12. Long XD,Ma Y,Wei YP, Deng ZL. The polymorphisms of GSTM1, GSTT1, HYL1*2, and XRCC1, and aflatoxin B1-related hepatocellular carcinoma in Guangxi population, China. Hepatol Res. 2006;36:48-55.
13. Kiran M, Chawla YK, Kaur J. Glutathione-S-transferase and microsomal epoxide hydrolase polymorphismand viral-related hepatocellular carcinoma risk in India. DNA Cell Biol. 2008;27:687-94.
14. He SJ, Gu YY, Lin WZ, Zeng XY, Liao ZH. Polymorphism of microsomal epoxide hydrolase and susceptibility to primary hepatocellular carcinoma. Tumor. 2008;28:125-8.
15. Wei YP, Ma Y, Deng ZL. Aflatoxin high-risk patients with hepatocellular carcinoma microsomal oxide hydrolase gene detection. Zhong Liu Fang Zhi Za Zhi. 2003;10:1009-11.
16. Liu ZG. Detoxifying enzyme gene GSTT-1, EPHX polymorphisms associated with hepatocellular carcinoma. Guangxi: Guangxi Medical University; 2003. p. 1-80.
17. Hassett C, Aicher L, Sidhu JS, Omiecinski CJ. Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants. Hum Mol Genet. 1994;3:421-8.
18. Goode EL, White KL, Vierkant RA, Phelan CM, Cunningham JM, et al. Xenobiotic-metabolizing gene polymorphisms and ovarian cancer risk. Mol Carcinog. 2011;50:397-402.
19. Pinarbasi H, Silig Y, Pinarbasi E. Microsomal epoxide hydrolase polymorphisms. Mol Med Report. 2010;3:723-7.
20. Zhong J-H, Xiang B-D,Ma L, You X-M, Li L-Q, et al.Meta-analysis of microsomal epoxide hydrolase gene polymorphism and risk of hepatocellular carcinoma. PLoS ONE. 2013;8:e57064. doi:10.1371/ journal.pone.0057064.
21. Petitti DB. Approaches to heterogeneity in meta-analysis. Stat Med. 2001;20:3625-33.