Source activation of P300 correlates with negative symptom severity in patients with schizophrenia

Brain Topography

Volumn 27, Issue 2, 2014, Pages 307-317

  Kim, Do Won ^a,b   Shim, Miseon ^a,b   Kim, Jeong In ^b,c   Im, Chang Hwan ^a   Lee, Seung Hwan ^b,c  

^a Hanyang University   (South Korea)

^b Clinical Emotion and Cognition Research Laboratory   (South Korea)

^c Inje University College of Medicine   (South Korea)

Author keywords

Biomarker; Negative symptom; P300; Schizophrenia; Source activity

Indexed keywords

ADULT; BRAIN; ELECTROENCEPHALOGRAPHY; EVENT-RELATED POTENTIALS, P300; FEMALE; HUMANS; MALE; SCHIZOPHRENIA; SEVERITY OF ILLNESS INDEX; SYMPTOM ASSESSMENT;

EID: 84894465286     PISSN: 08960267     EISSN: 15736792     Source Type: Journal    
DOI: 10.1007/s10548-013-0306-x     Document Type: Article

References (67)

1. Anderer P, Pascual-Marqui RD, Semlitsch HV, Saletu B (1998) Electrical sources of P300 event-related brain potentials revealed by low resolution electromagnetic tomography.1. Effects of normal aging. Neuropsychobiology 37(1):20-27. doi: 10.1159/000026472
2. Anderson JE, Wible CG, McCarley RW, Jakab M, Kasai K, Shenton ME (2002) An MRI study of temporal lobe abnormalities and negative symptoms in chronic schizophrenia. Schizophr Res 58(2-3):123-134. doi: 10.1016/S0920-9964(01)00372-3
3. Barta PE, Pearlson GD, Powers RE, Richards SS, Tune LE (1990) Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia. Am J Psychiat 147(11):1457-1462
4. Blackwood DH, Whalley LJ, Christie JE, Blackburn IM, St Clair DM, McInnes A (1987) Changes in auditory P3 event-related potential in schizophrenia and depression. Br j Psychiatry 150:154-160
5. Bleich-Cohen M, Sharon H, Weizman R, Poyurovsky M, Faragian S, Hendler T (2012) Diminished language lateralization in schizophrenia corresponds to impaired inter-hemispheric functional connectivity. Schizophr Res 134(2-3):131-136. doi: 10.1016/j.schres.2011.10.011
6. Boutros NN, Mucci A, Diwadkar V, Tandon R (2013) Negative symptoms in schizophrenia. Clin Schizophr Relat Psychos. doi: 10.3371/CSRP.BOMU.012513
7. Braff DL, Light GA (2004) Preattentional and attentional cognitive deficits as targets for treating schizophrenia. Psychopharmacology 174(1):75-85. doi: 10.1007/s00213-004-1848-0
8. Bramon E, Rabe-Hesketh S, Sham P, Murray RM, Frangou S (2004) Meta-analysis of the P300 and P50 waveforms in schizophrenia. Schizophr Res 70(2-3):315-329. doi: 10.1016/j.schres.2004.01.004
9. Bruder G, Kayser J, Tenke C, Amador X, Friedman M, Sharif Z, Gorman J (1999) Left temporal lobe dysfunction in schizophrenia: event-related potential and behavioral evidence from phonetic and tonal dichotic listening tasks. Arch Gen Psychiatry 56(3):267-276
10. Calhoun VD, Adali T, Giuliani NR, Pekar JJ, Kiehl KA, Pearlson GD (2006) Method for multimodal analysis of independent source differences in schizophrenia: combining gray matter structural and auditory oddball functional data. Hum Brain Mapp 27(1):47-62. doi: 10.1002/hbm.20166
11. Coutanche MN, Thompson-Schill SL, Schultz RT (2011) Multi-voxel pattern analysis of fMRI data predicts clinical symptom severity. NeuroImage 57(1):113-123. doi: 10.1016/j.neuroimage.2011.04.016
12. Crow TJ (1990) Temporal-lobe asymmetries as the key to the etiology of schizophrenia. Schizophr Bull 16(3):433
13. Deakin JFW, Slater P, Simpson MDC, Gilchrist AC, Skan WJ, Royston MC, Reynolds GP, Cross AJ (1989) Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia. J Neurochem 52(6):1781-1786. doi: 10.1111/j.1471-4159.1989.tb07257.x
14. Egan MF, Duncan CC, Suddath RL, Kirch DG, Mirsky AF, Wyatt RJ (1994) Event-related potential abnormalities correlate with structural brain alterations and clinical features in patients with chronic schizophrenia. Schizophr Res 11(3):259-271
15. Eikmeier G, Lodemann E, Zerbin D, Gastpar M (1992) P300, clinical symptoms, and neuropsychological parameters in acute and remitted schizophrenia: a preliminary report. Biol Psychiatry 31(10):1065-1069
16. Faux SF, Mccarley RW, Nestor PG, Shenton ME, Pollak SD, Penhune V, Mondrow E, Marcy B, Peterson A, Horvath T, Davis KL (1993) P300 topographic asymmetries are present in unmedicated schizophrenics. Electroencephalogr Clin Neurophysiol 88(1):32-41. doi: 10.1016/0168-5597(93)90026-L
17. First MB, Gibbon M (1997) User's guide for the structured clinical interview for Dsm-IV Axis II personality disorders: Scid-II. American Psychiatric Press, Arlington
18. First MB, Spitzer RL, Williams JBW (1997) Structured clinical interview for DSM-IV Axis I disorders SCID-I: clinician version, administration booklet. American Psychiatric Press, Arlington
19. Ford JM (1999) Schizophrenia: the broken P300 and beyond. Psychophysiology 36(6):667-682. doi: 10.1017/S0048577299990479
20. Ford JM, Pfefferbaum A, Roth W (1992) P3 and schizophrenia. Ann N Y Acad Sci 658:146-162
21. Fuchs M, Kastner J, Wagner M, Hawes S, Ebersole JS (2002) A standardized boundary element method volume conductor model. Clin Neurophysiol 113(5):702-712. doi: 10.1016/S1388-2457(02)00030-5
22. Galderisi S, Maj M (2009) Deficit schizophrenia: an overview of clinical, biological and treatment aspects. Eur Psychiat 24(8):493-500. doi: 10.1016/j.eurpsy.2009.03.001
23. Galderisi S, Mucci A, Volpe U, Boutros N (2009) Evidence-based medicine and electrophysiology in schizophrenia. Clin Eeg Neurosci 40(2):62-77
24. Havermans R, Honig A, Vuurman EFPM, Krabbendam L, Wilmink J, Lamers T, Verheecke CJ, Jolles J, Romme MAJ, van Praag HM (1999) A controlled study of temporal lobe structure volumes and P300 responses in schizophrenic patients with persistent auditory hallucinations. Schizophr Res 38(2-3):151-158. doi: 10.1016/S0920-9964(99)00006-7
25. Higashima M, Nagasawa T, Kawasaki Y, Oka T, Sakai N, Tsukada T, Koshino Y (2003) Auditory P300 amplitude as a state marker for positive symptoms in schizophrenia: cross-sectional and retrospective longitudinal studies. Schizophr Res 59(2-3):147-157. doi: 10.1016/S0920-9964(01)00397-8
26. Higuchi Y, Sumiyoshi T, Kawasaki Y, Matsui M, Arai H, Kurachi M (2008) Electrophysiological basis for the ability of olanzapine to improve verbal memory and functional outcome in patients with schizophrenia: a LORETA analysis of P300. Schizophr Res 101(1-3):320-330. doi: 10.1016/j.schres.2008.01.020
27. Jeon YW, Polich J (2001) P300 asymmetry in schizophrenia: a meta-analysis. Psychiat Res 104(1):61-74. doi: 10.1016/S0165-1781(01)00297-9
28. Josiassen RC, Roemer RA, Johnson MM, Shagass C (1990) Are gender differences in schizophrenia reflected in brain event-related potentials. Schizophr Bull 16(2):229-246
29. Jung HT, Kim DW, Kim S, Im CH, Lee SH (2012) Reduced source activity of event-related potentials for affective facial pictures in schizophrenia patients. Schizophr Res 136(1-3):150-159. doi: 10.1016/j.schres.2011.10.023
30. Kaustio O, Partanen J, Valkonen-Korhonen M, Viinamäki H, Lehtonen J (2002) Affective and psychotic symptoms relate to different types of P300 alteration in depressive disorder. J Affect Disord 71(1-3):43-50. doi: 10.1016/S0165-0327(01)00410-4
31. Kawasaki Y, Sumiyoshi T, Higuchi Y, Ito T, Takeuchi M, Kurachi M (2007) Voxel-based analysis of P300 electrophysiological topography associated with positive and negative symptoms of schizophrenia. Schizophr Res 94(1-3):164-171. doi: 10.1016/j.schres.2007.04.015
32. Kay SR, Fiszbein A, Opler LA (1987) The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 13(2):261-276
33. Kochi K, Koenig T, Strik WK, Lehmann D (1996) Event-related potential P300 microstate topography during visual one- and two-dimensional tasks in chronic schizophrenics. Eur Arch Psychiatry Clin Neurosci 246(6):288-296
34. Lantz G, Michel CM, Pascual-Marqui RD, Spinelli L, Seeck M, Seri S, Landis T, Rosen I (1997) Extracranial localization of intracranial interictal epileptiform activity using LORETA (low resolution electromagnetic tomography). Electroencephalogr Clin Neurophysiol 102(5):414-422
35. Lee MS, Lee SH, Moon EO, Moon YJ, Kim S, Kim SH, Jung IK (2013) Neuropsychological correlates of the P300 in patients with Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry 40:62-69. doi: 10.1016/j.pnpbp.2012. 08.009
36. Lim Y, Lee SH, Hong SI (2010) Application of N100, P300 and QEEG as a biological marker in patients with schizophrenia. Korean J Psychopharmacol 21:78-86
37. Liu Z, Tam WC, Xue Z, Yao S, Wu D (2004) Positive and negative symptom profile schizophrenia and abnormalities in the P300 component of the event-related potential: a longitudinal controlled study. Psychiatry Res 132(2):131-139. doi: 10.1016/j.pscychresns.2004.03.003
38. Mccarley RW, Shenton ME, Odonnell BF, Faux SF, Kikinis R, Nestor PG, Jolesz FA (1993) Auditory P300 abnormalities and left posterior superior temporal gyrus volume reduction in schizophrenia. Arch Gen Psychiat 50(3):190-197
39. Michie PT, Fox AM, Ward PB, Catts SV, Mcconaghy N (1990) Event-related potential indexes of selective attention and cortical lateralization in schizophrenia. Psychophysiology 27(2):209-227. doi: 10.1111/j.1469-8986.1990. tb00372.x
40. Pae JS, Kwon JS, Youn T, Park HJ, Kim MS, Lee B, Park KS (2003) LORETA imaging of P300 in schizophrenia with individual MRI and 128-channel EEG. NeuroImage 20(3):1552-1560
41. Pascual-Marqui RD (2002) Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details. Method Find Exp Clin 24:5-12
42. Pascual-Marqui RD, Esslen M, Kochi K, Lehmann D (2002) Functional imaging with low-resolution brain electromagnetic tomography (LORETA): a review. Method Find Exp Clin 24:91-95
43. Pearlson GD (1997) Superior temporal gyrus and planum temporale in schizophrenia: a selective review. Prog Neuropsychopharmacol Biol Psychiatry 21(8):1203-1229. doi: 10.1016/S0278-5846(97)00159-0
44. Pfefferbaum A, Ford JM, White PM, Roth WT (1989) P3 in schizophrenia is affected by stimulus modality, response requirements, medication status, and negative symptoms. Arch Gen Psychiatry 46(11):1035-1044
45. Salisbury DF, Shenton ME, Sherwood AR, Fischer IA, YurgelunTodd DA, Tohen M (1998) McCarley RW (1998) First-episode schizophrenic psychosis differs from first-episode affective psychosis and controls in P300 amplitude over left temporal lobe (vol 55, pg 173. Arch Gen Psychiat 55(5):413
46. Santosh PJ, Malhotra S, Raghunathan M, Mehra YN (1994) A study of p300 in melancholic depression-correlation with psychotic features. Biol Psychiatry 35(7):474-479. doi: 10.1016/0006-3223(94)90046-9
47. Sekihara K, Sahani M, Nagarajan SS (2005) Localization bias and spatial resolution of adaptive and non-adaptive spatial filters for MEG source reconstruction. NeuroImage 25(4):1056-1067. doi: 10.1016/j.neuroimage.2004.11. 051
48. Semlitsch HV, Anderer P, Schuster P, Presslich O (1986) A solution for reliable and valid reduction of ocular artifacts, applied to the P300 ERP. Psychophysiology 23(6):695-703
49. Shenton ME, Kikinis R, Jolesz FA, Pollak SD, LeMay M, Wible CG, Hokama H, Martin J, Metcalf D, Coleman M, McCarley RW (1992) Abnormalities of the left temporal lobe and thought disorder in schizophrenia. N Engl J Med 327(9):604-612. doi: 10.1056/NEJM199208273270905
50. St Clair D, Blackwood D, Muir W (1989) P300 abnormality in schizophrenic subtypes. J Psychiatr Res 23(1):49-55
51. Stefansson SB, Jonsdottir TJ (1996) Auditory event-related potentials, auditory digit span, and clinical symptoms in chronic schizophrenic men on neuroleptic medication. Biol Psychiatry 40(1):19-27. doi: 10.1016/0006-3223(95) 00351-7
52. Strik WK, Dierks T, Maurer K (1993) Amplitudes of auditory P300 in remitted and residual schizophrenics: correlations with clinical features. Neuropsychobiology 27(1):54-60. doi: 118953
53. Strik WK, Dierks T, Franzek E, Stober G, Maurer K (1994) P300 asymmetries in schizophrenia revisited with reference-independent methods. Psychiatry Res 55(3):153-166
54. Sumiyoshi T, Higuchi Y, Kawasaki Y, Matsui M, Kato K, Yuuki H, Arai H, Kurachi M (2006) Electrical brain activity and response to olanzapine in schizophrenia: a study with LORETA images of P300. Prog Neuropsychopharmacol Biol Psychiatry 30(7):1299-1303. doi: 10.1016/j.pnpbp.2006.04.028
55. Sumiyoshi T, Higuchi Y, Itoh T, Matsui M, Arai H, Suzuki M, Kurachi M, Sumiyoshi C, Kawasaki Y (2009) Effect of perospirone on P300 electrophysiological activity and social cognition in schizophrenia: a three-dimensional analysis with sLORETA. Psychiat Res Neuroim 172(3):180-183. doi: 10.1016/j.pscychresns.2008.07.005
56. Turetsky BI, Colbath EA, Gur RE (1998) P300 subcomponent abnormalities in schizophrenia: i. Physiological evidence for gender and subtype specific differences in regional pathology. Biol Psychiatry 43(2):84-96. doi: 10.1016/S0006-3223(97)00258-8
57. Umbricht D, Javitt D, Novak G, Bates J, Pollack S, Lieberman J, Kane J (1998) Effects of clozapine on auditory event-related potentials in schizophrenia. Biol Psychiatry 44(8):716-725. doi: 10.1016/S0006-3223(97)00524-6
58. van der Stelt O, Lieberman JA, Belger A (2005) Auditory P300 in high-risk, recent-onset and chronic schizophrenia. Schizophr Res 77(2-3):309-320. doi: 10.1016/j.schres.2005.04.024
59. Volpe U, Mucci A, Bucci P, Merlotti E, Galderisi S, Maj M (2007) The cortical generators of P3a and P3b: a LORETA study. Brain Res Bull 73(4-6):220-230. doi: 10.1016/j.brainresbull.2007.03.003
60. Wang JJ, Hiramatsu KI, Hokama H, Miyazato H, Ogura C (2003) Abnormalities of auditory P300 cortical current density in patients with schizophrenia using high density recording. Int J Psychophysiol 47(3):243-253. doi: 10.1016/S0167-8760(02)00157-5
61. Wang JJ, Tang YX, Li CB, Mecklinger A, Xiao ZP, Zhang MD, Hirayasu Y, Hokama H, Li H (2010) Decreased P300 current source density in drug-naive first episode schizophrenics revealed by high density recording. Int J Psychophysiol 75(3):249-257. doi: 10.1016/j.ijpsycho.2009.12.005
62. Weinberger DR (1988) Schizophrenia and the frontal lobe. Trends Neurosci 11(8):367-370. doi: 10.1016/0166-2236(88)90060-4
63. Winterer G, Mulert C, Mientus S, Gallinat J, Schlattmann P, Dorn H, Herrmann WM (2001) P300 and LORETA: comparison of normal subjects and schizophrenic patients. Brain Topogr 13(4):299-313. doi: 10.1023/A:1011184814194
64. Wolf DH, Turetsky BI, Loughead J, Elliott MA, Pratiwadi R, Gur RE, Gur RC (2008) Auditory oddball fMRI in schizophrenia: association of negative symptoms with regional hypoactivation to novel distractors. Brain Imaging Behav 2(2):132-145. doi: 10.1007/s11682-008-9022-7
65. Wolkin A, Sanfilipo M, Wolf AP, Angrist B, Brodie JD, Rotrosen J (1992) Negative symptoms and hypofrontality in chronic schizophrenia. Arch Gen Psychiat 49(12):959-965. doi: 10.1001/archpsyc.1992.01820120047007
66. Yamasue H, Yamada H, Yumoto M, Kamio S, Kudo N, Uetsuki M, Abe O, Fukuda R, Aoki S, Ohtomo K, Iwanami A, Kato N, Kasai K (2004) Abnormal association between reduced magnetic mismatch field to speech sounds and smaller left planum temporale volume in schizophrenia. NeuroImage 22(2):720-727. doi: 10.1016/j.neuroimage.2004.01.042
67. Ziauddeen H, Dibben C, Kipps C, Hodges JR, McKenna PJ (2011) Negative schizophrenic symptoms and the frontal lobe syndrome: one and the same? Eur Arch Psy Clin N 261(1):59-67. doi: 10.1007/s00406-010-0133-y