Impact of seasonal flux on 25-hydroxyvitamin D and bone turnover in pre- and early pubertal youth

Pediatrics International

Volumn 56, Issue 1, 2014, Pages 35-42

  Rajakumar, Kumaravel ^a   Holick, Michael F ^c   Moore, Charity G ^b   Cohen, Elan ^b   Olabopo, Flora ^a   Haralam, Mary Ann ^a   Bogusz, Jaimee ^c   Nucci, Anita ^d   Greenspan, Susan L ^b  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d GEORGIA STATE UNIVERSITY   (United States)

Author keywords

25 hydroxyvitamin D; biomarkers; bone turnover; children; collagen type 1 cross linked C telopeptide; osteocalcin; parathyroid hormone; season; vitamin D

Indexed keywords

25-HYDROXYVITAMIN D; VITAMIN D;

ANALOGS AND DERIVATIVES; BODY MASS; BONE; BONE DENSITY; CHILD; FEMALE; FOLLOW UP; HUMAN; MALE; METABOLISM; NORMAL HUMAN; PHYSIOLOGY; PUBERTY; RETROSPECTIVE STUDY; SEASON;

BODY MASS INDEX; BONE AND BONES; BONE DENSITY; CHILD; FEMALE; FOLLOW-UP STUDIES; HEALTHY VOLUNTEERS; HUMANS; MALE; PUBERTY; RETROSPECTIVE STUDIES; SEASONS; VITAMIN D;

EID: 84894424822     PISSN: 13288067     EISSN: 1442200X     Source Type: Journal    
DOI: 10.1111/ped.12210     Document Type: Article

References (41)

1. DeLuca HF,. Overview of general physiologic features and functions of vitamin D. Am. J. Clin. Nutr. 2004; 80 (6 Suppl.): 1689S-1696.
2. Institute of Medicine. Dietary Reference Intakes for Calcium and Vitamin D. National Academies Press, Washington, DC, 2011.
3. Haddad JG Jr, Hahn TJ,. Natural and synthetic sources of circulating 25-hydroxyvitamin D in man. Nature 1973; 244 (5417): 515-517.
4. Lawson DE, Paul AA, Black AE, Cole TJ, Mandal AR, Davie M,. Relative contributions of diet and sunlight to vitamin D state in the elderly. Br. Med. J. 1979; 2 (6185): 303-305.
5. Poskitt EM, Cole TJ, Lawson DE,. Diet, sunlight, and 25-hydroxy vitamin D in healthy children and adults. Br. Med. J. 1979; 1 (6158): 221-223.
6. Webb AR, Kline L, Holick MF,. Influence of season and latitude on the cutaneous synthesis of vitamin D3: Exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin. J. Clin. Endocrinol. Metab. 1988; 67: 373-378.
7. Holick MF,. Vitamin D: A millennium perspective. J. Cell. Biochem. 2003; 88: 296-307.
8. Webb AR,. Who, what, where and when: Influences on cutaneous vitamin D synthesis. Prog. Biophys. Mol. Biol. 2006; 92: 17-25.
9. McKenna MJ, Freaney R,. Secondary hyperparathyroidism in the elderly: Means to defining hypovitaminosis D. Osteoporos. Int. 1998; 8 (Suppl. 2): S3-6.
10. Slemenda CW, Peacock M, Hui S, Zhou L, Johnston CC,. Reduced rates of skeletal remodeling are associated with increased bone mineral density during the development of peak skeletal mass. J. Bone Miner. Res. 1997; 12: 676-682.
11. Rapuri PB, Kinyamu HK, Gallagher JC, Haynatzka V,. Seasonal changes in calciotropic hormones, bone markers, and bone mineral density in elderly women. J. Clin. Endocrinol. Metab. 2002; 87: 2024-2032.
12. Pasco JA, Henry MJ, Kotowicz MA, et al. Seasonal periodicity of serum vitamin D and parathyroid hormone, bone resorption, and fractures: The Geelong Osteoporosis Study. J. Bone Miner. Res. 2004; 19: 752-758.
13. Viljakainen HT, Palssa A, Karkkainen M, et al. A seasonal variation of calcitropic hormones, bone turnover and bone mineral density in early and mid-puberty girls: A cross-sectional study. Br. J. Nutr. 2006; 96: 124-130.
14. Heaney RP, Abrams S, Dawson-Hughes B, et al. Peak bone mass. Osteoporos. Int. 2000; 11: 985-1009.
15. Rajakumar K, Holick MF, Jeong K, et al. Impact of season and diet on vitamin D status of African American and Caucasian children. Clin. Pediatr. (Phila) 2011; 50: 493-502.
16. Marshall WA, Tanner JM,. Variations in pattern of pubertal changes in girls. Arch. Dis. Child. 1969; 44 (235): 291-303.
17. Marshall WA, Tanner JM,. Variations in the pattern of pubertal changes in boys. Arch. Dis. Child. 1970; 45 (239): 13-23.
18. Nucci AM, Russell C, Luo R, et al. The effectiveness of a short food frequency questionnaire in determining vitamin D intake in children. Dermato-Endocrinology 2013; 5: 205-210.
19. Pathak MA, Jimbow K, Szabo G, et al. Sunlight and melanin pigmentation. In:, Smith K, (ed). Photochemical and Photobiological Reviews. Plenum Press, New York, 1976; 211-239.
20. Jimbow K, Fitzpatrick TB, Wick WM,. Biochemistry and physiology of melanin pigmentation. In:, Goldsmith L, (ed). Physiology, Biochemistry, and Molecular Biology of the Skin. Oxford University Press, New York, 1991; 873-909.
21. Holick MF, Siris ES, Binkley N, et al. Prevalence of Vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy. J. Clin. Endocrinol. Metab. 2005; 90: 3215-3224.
22. Wagner CL, Greer FR,. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics 2008; 122: 1142-1152.
23. Cashman KD, Hill TR, Cotter AA, et al. Low vitamin D status adversely affects bone health parameters in adolescents. Am. J. Clin. Nutr. 2008; 87: 1039-1044.
24. Cheng S, Tylavsky F, Kroger H, et al. Association of low 25-hydroxyvitamin D concentrations with elevated parathyroid hormone concentrations and low cortical bone density in early pubertal and prepubertal Finnish girls. Am. J. Clin. Nutr. 2003; 78: 485-492.
25. Lehtonen-Veromaa MK, Mottonen TT, Nuotio IO, Irjala KM, Leino AE, Viikari JS,. Vitamin D and attainment of peak bone mass among peripubertal Finnish girls: A 3-y prospective study. Am. J. Clin. Nutr. 2002; 76: 1446-1453.
26. Outila TA, Karkkainen MU, Lamberg-Allardt CJ,. Vitamin D status affects serum parathyroid hormone concentrations during winter in female adolescents: Associations with forearm bone mineral density. Am. J. Clin. Nutr. 2001; 74: 206-210.
27. Docio S, Riancho JA, Perez A, Olmos JM, Amado JA, Gonzalez-Macias J,. Seasonal deficiency of vitamin D in children: A potential target for osteoporosis-preventing strategies? J. Bone Miner. Res. 1998; 13: 544-548.
28. El-Hajj Fuleihan G, Nabulsi M, Choucair M, et al. Hypovitaminosis D in healthy schoolchildren. Pediatrics 2001; 107: E53.
29. Gordon CM, DePeter KC, Feldman HA, Grace E, Emans SJ,. Prevalence of vitamin D deficiency among healthy adolescents. Arch. Pediatr. Adolesc. Med. 2004; 158: 531-537.
30. Guillemant J, Cabrol S, Allemandou A, Peres G, Guillemant S,. Vitamin D-dependent seasonal variation of PTH in growing male adolescents. Bone 1995; 17: 513-516.
31. Guillemant J, Le HT, Maria A, Allemandou A, Peres G, Guillemant S,. Wintertime vitamin D deficiency in male adolescents: Effect on parathyroid function and response to vitamin D3 supplements. Osteoporos. Int. 2001; 12: 875-879.
32. Brenza HL, Kimmel-Jehan C, Jehan F, et al. Parathyroid hormone activation of the 25-hydroxyvitamin D3-1alpha-hydroxylase gene promoter. Proc. Natl Acad. Sci. USA 1998; 95: 1387-1391.
33. Bonofiglio D, Maggiolini M, Catalano S, et al. Parathyroid hormone is elevated but bone markers and density are normal in young female subjects who consume inadequate dietary calcium. Br. J. Nutr. 2000; 84: 111-116.
34. Tylavsky FA,. Seasonal variation in calcitropic hormones and bone accrual in puberty. Br. J. Nutr. 2006; 96: 4-6.
35. Heaney RP, Holick MF,. Why the IOM recommendations for vitamin D are deficient. J. Bone Miner. Res. 2011; 26: 455-457.
36. Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: An Endocrine Society clinical practice guideline. J. Clin. Endocrinol. Metab. 2011; 96: 1911-1930.
37. Harkness L, Cromer B,. Low levels of 25-hydroxy vitamin D are associated with elevated parathyroid hormone in healthy adolescent females. Osteoporos. Int. 2005; 16: 109-113.
38. Hill KM, McCabe GP, McCabe LD, Gordon CM, Abrams SA, Weaver CM,. An inflection point of serum 25-hydroxyvitamin D for maximal suppression of parathyroid hormone is not evident from multi-site pooled data in children and adolescents. J. Nutr. 2010; 140: 1983-1988.
39. Fraser WD, Ahmad AM, Vora JP,. The physiology of the circadian rhythm of parathyroid hormone and its potential as a treatment for osteoporosis. Curr. Opin. Nephrol. Hypertens. 2004; 13: 437-444.
40. Heuck C, Skjaerbaek C, Wolthers OD,. Diurnal rhythm of serum osteocalcin in normal children. Acta Paediatr. 1998; 87: 930-932.
41. Clowes JA, Hannon RA, Yap TS, Hoyle NR, Blumsohn A, Eastell R,. Effect of feeding on bone turnover markers and its impact on biological variability of measurements. Bone 2002; 30: 886-890.