Racial differences in vasopressor requirements for septic shock

Shock

Volumn 41, Issue 3, 2014, Pages 188-192

  Bauman, Zachary M ^a   Killu, Keith F ^a   Rech, Megan A ^b   Bernabei Combs, Jenna L ^c   Gassner, Marika Y ^a   Coba, Victor E ^a   Tovbin, Alina ^a   Kunkel, Patti L ^a   Mlynarek, Mark E ^a  

^a HENRY FORD HOSPITAL   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c Providence Hospital Mobile   (United States)

Author keywords

African American; hypotension; norepinephrine; race; septic shock; Vasopressors

Indexed keywords

AFRICAN AMERICANS; AGED; AGED, 80 AND OVER; DOSE-RESPONSE RELATIONSHIP, DRUG; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HOSPITALS, TEACHING; HUMANS; HYPERTENSION; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SHOCK, SEPTIC; TERTIARY CARE CENTERS; TIME FACTORS; VASOCONSTRICTOR AGENTS;

EID: 84894416600     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000103     Document Type: Article

References (26)

1. Havel C, Arrich J, Losert H, Gamper G, Mullner M, Herkner H: Vasopressors for hypotensive shock. Cochrane Database Syst Rev 5:CD003709, 2011.
2. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, et al.: Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med 41(2):580-637, 2013.
3. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G, et al.: International Sepsis Definitions Conference. Crit Care Med 31(4):1250-1256, 2003.
4. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345(19):1368-1377, 2001.
5. Azevedo LC, Park M, Schettino GP: Novel potential therapies for septic shock. Shock 30(Suppl 1):60-66, 2008.
6. Esteban A, Frutos-Vivar F, Ferguson ND, Penuelas O, Lorente JA, Gordo F, Honrubia T, Algora A, Bustos A, Garcia G, et al.: Sepsis incidence and outcome: contrasting the intensive care unit with the hospital ward. Crit Care Med 35(5):1284-1289, 2007.
7. Martin GS, Mannino DM, Eaton S, Moss M: The epidemiology of sepsis in the United States from 1979 through 2000. N Engl JMed 348(16):1546-1554, 2003.
8. Alberti C, Brun-Buisson C, Chevret S, Antonelli M, Goodman SV, Martin C, Moreno R, Ochagavia AR, Palazzo M, Werdan K, et al.: Systemic inflammatory response and progression to severe sepsis in critically ill infected patients. Am J Respir Crit Care Med 171(5):461-468, 2005.
9. Schnell D, Besset S, Lengliné E, Maziers N, Zafrani L, Reuter D, Moreau AS, Canet E, Lemiale V, Azoulay E: Impact of a recent chemotherapy on the duration and intensity of the norepinephrine support during septic shock. Shock 39(2): 138-143, 2013.
10. Adams JM: Some racial differences in blood pressures and morbidity in a group of white and colored workmen. Am J Med Sci 184:342, 1932.
11. Falkner B: Differences in blacks and whites with essential hypertension: biochemistry and endocrine. Hypertension 15(6 Pt 2):681-686, 1990.
12. Gillum RF: Pathophysiology of hypertension in black and whites: a review of the basis of racial blood pressure differences. Hypertension 1(5):468-475, 1979.
13. Murphy JK, Alpert BS, Moes DM, Somes GW: Race and cardiovascular reactivity: a neglected relationship. Hypertension 8(11):1075-1083, 1986.
14. Dimsdale JE, Graham RM, Ziegler MG, Zusman RM, Berry CC: Age, race diagnosis and sodium effects on the pressor response to infused norepinephrine. Hypertension 10(6):564-569, 1987.
15. Sherwood A, Hinderliter AL: Responses to alpha- and beta-adrenergic receptor agonists: effects of race in borderline hypertensive compared to normotensive man. Am J Hypertens 6(7 Pt 1):630-635, 1993.
16. Svetky LP, Chen YT, McKeown SP, Preis L,Wilson AF: Preliminary evidence of linkage of salt sensitivity in black Americans at the beta2Vadrenergic receptor locus. Hypertension 29(4):918-922, 1997.
17. Lovenberg W, Bruckwick EA, Alexander RW, Horwitz D, Keiser HR: Evaluation of serum dopamine-beta-hydroxylase activity as an index of sympathetic nervous activity in man. Adv Biochem Psychopharmacol 12(0): 121-128, 1974.
18. Mills PJ, Dimsdale JE, Ziegler MG, Nelesen RA: Racial differences in epinephrine and beta2-adrenergic receptors. Hypertension 25(1):88-91, 1995.
19. Freedman RR, Girgis R: Effects of menstrual cycle and race on peripheral vascular [alpha]-adrenergic responsiveness. Hypertension 35(3):795-799, 2000.
20. Lang CC, Stein CM, He HB, Belas FJ, Blair IA, Wood M, Wood AJ. Blunted blood pressure response to central sympathoinhibition in normotensive blacks: increased importance of nonsympathetic factors in blood pressure maintenance in blacks. Hypertension 30(2 Pt 1):157-162, 1997.
21. Small KM, McGraw DW, Liggett SB: Pharmacology and physiology of human adrenergic receptor polymorphisms. Annu Rev Pharmacol Toxicol 43: 381-411, 2003.
22. Goldstein DS: Plasma catecholamines and essential hypertension: an analytical review. Hypertension 5(1):86-99, 1983.
23. Suarez EC, Saab PG, Llabre MM, Kuhn CM, Zimmerman E: Ethnicity, gender, and age effects of adrenoceptors and physiological responses to emotional stress. Psychophysiology 41(3):450-460, 2004.
24. Svetkey LP, Timmons PZ, Emovon O, Anderson NB, Preis L, Chen YT: Association of hypertension with beta2- and alpha2c10Vadrenergic receptor genotype. Hypertension 27(6):1210-1215, 1996.
25. Ferguson-Myrthil N: Vasopressor use in adult patients. Cardiol Rev 20(3): 153-158, 2012.
26. Persichini R, Silva S, Teboul JL, Jozwiak M, Chemla D, Richard C, Monnet X. Effects of norepinephrine on mean systemic pressures and venous return in human septic shock. Crit Care Med 40(12):3146-3153, 2012.