IP-10/CXCL10 and MIG/CXCL9 as novel markers for the diagnosis of lymphoma-associated hemophagocytic syndrome

Annals of Hematology

Volumn 93, Issue 3, 2014, Pages 393-401

  Maruoka, Hayato ^a   Inoue, Daichi ^b   Takiuchi, Yoko ^a   Nagano, Seiji ^a   Arima, Hiroshi ^a   Tabata, Sumie ^a   Matsushita, Akiko ^a   Ishikawa, Takayuki ^a   Oita, Tatsuo ^a   Takahashi, Takayuki ^c  

^a KOBE CITY MEDICAL CENTER GENERAL HOSPITAL   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c Shinko Hospital   (Japan)

Author keywords

Cytometric bead array; IP 10; Lymphoma associated hemophagocytic syndrome; MIG

Indexed keywords

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; CHEMOKINE CXCL10; CHEMOKINE CXCL9; DIAGNOSIS, DIFFERENTIAL; FOLLOW-UP STUDIES; HOSPITALS, URBAN; HUMANS; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; LYMPHOMA, NON-HODGKIN; MIDDLE AGED; NEOPLASM STAGING; REAGENT KITS, DIAGNOSTIC; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84894387553     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-013-1878-y     Document Type: Article

References (50)

1. Tsuda H (1997) Hemophagocytic syndrome (HPS) in children and adults. Int J Hematol 65:215-226
2. Imashuku S (1997) Differential diagnosis of hemophagocytic syndrome: underlying disorders and selection of the most effective treatment. Int J Hematol 66:135-151
3. Henter JI, Horne A, Aricó M, Egeler RM, Filipovich AH, Imashuku S, Ladisch S, McClain K, Webb D, Winiarski J, Janka G (2007) HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Canc 48:124-131
4. Henter JI, Elinder G, Söder O, Hansson M, Andersson B, Andersson U (1991) Hypercytokinemia in familial hemophagocytic lymphohistiocytosis. Blood 78:2918-2922
5. Fujiwara F, Hibi S, Imashuku S (1993) Hypercytokinemia in hemophagocytic syndrome. Am J Pediatr Hematol Oncol 15:92-98
6. Akashi K, Hayashi S, Gondo H, Mizuno S, Harada M, Tamura K, Yamasaki K, Uike N, Okamura T, Miyamoto T, Niho Y (1994) Involvement of interferon-gamma and macrophage colony-stimulating factor in pathogenesis of haemophagocytic lymphohistiocytosis in adults. Br J Haematol 87:243-250
7. Osugi Y, Hara J, Tagawa S, Takai K, Hosoi G, Matsuda Y, Ohta H, Fujisaki H, Kobayashi M, Sakata N, Kawa-Ha K, Okada S, Tawa A (1997) Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosis. Blood 89:4100-4103
8. Takada H, Nomura A, Ohga S, Hara T (2001) Interleukin-18 in hemophagocytic lymphohistiocytosis. Leuk Lymphoma 42:21-28
9. Mazodier K, Marin V, Novick D, Farnarier C, Robitail S, Schleinitz N, Veit V, Paul P, Rubinstein M, Dinarello CA, Harlé JR, Kaplanski G (2005) Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome. Blood 106:3483-3489
10. Murohashi I, Yoshida K, Ihara N, Wakao D, Yagasaki F, Nakamura Y, Kawai N, Matsuda A, Jinnai I, Bessho M (2006) Serum levels of Th1/Th2 cytokines, angiogenic growth factors, and other prognostic factors in young adult patients with hemophagocytic syndrome. Lab Hematol 12:71-74
11. Ishii E, Ohga S, Imashuku S, Yasukawa M, Tsuda H, Miura I, Yamamoto K, Horiuchi H, Takada K, Ohshima K, Nakamura S, Kinukawa N, Oshimi K, Kawa K (2007) Nationwide survey of hemophagocytic lymphohistiocytosis in Japan. Int J Hematol 86:58-65
12. Shimazaki C, Inaba T, Nakagawa M (2000) B-cell lymphoma-associated hemophagocytic syndrome. Leuk Lymphoma 38:121-130
13. Takahashi N, Chubachi A, Kume M, Hatano Y, Komatsuda A, Kawabata Y, Yanagiya N, Ichikawa Y, Miura AB, Miura I (2001) A clinical analysis of 52 adult patients with hemophagocytic syndrome: the prognostic significance of the underlying diseases. Int J Hematol 74:209-213
14. Go RS, Wester SM (2004) Immunophenotypic and molecular features, clinical outcomes, treatments, and prognostic factors associated with subcutaneous panniculitis-like T-cell lymphoma. Cancer 101:1404-1413
15. Han AR, Lee HR, Park BB, Hwang IG, Park S, Lee SC, Kim K, Lim HY, Ko YH, Kim SH, Kim WS (2007) Lymphoma-associated hemophagocytic syndrome: clinical features and treatment outcome. Ann Hematol 86:493-498
16. Tong H, Ren Y, Liu H, Xiao F, Mai W, Meng H, Qian W, Huang J, Mao L, Tong Y, Wang L, Qian J, Jin J (2008) Clinical characteristics of T-cell lymphoma associated with hemophagocytic syndrome: comparison of T-cell lymphoma with and without hemophagocytic syndrome. Leuk Lymphoma 49:81-87
17. Ohga S, Matsuzaki A, Nishizaki M, Nagashima T, Kai T, Suda M, Ueda K (1993) Inflammatory cytokines in virus-associated hemophagocytic syndrome. Interferon-gamma as a sensitive indicator of disease activity. Am J Pediatr Hematol Oncol 15:291-298
18. Imashuku S, Hibi S, Tabata Y, Sako M, Sekine Y, Hirayama K, Sakazaki H, Maeda N, Kito H, Shichino H, Mugishima H (1998) Biomarker and morphological characteristics of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis. Med Pediatr Oncol 31:131-137
19. Tang Y, Xu X, Song H, Yang S, Shi S, Wei J, Pan B, Zhao F, Liao C, Luo C (2008) Early diagnostic and prognostic significance of a specific Th1/Th2 cytokine pattern in children with haemophagocytic syndrome. Br J Haematol 143:84-91
20. Miyahara M, Sano M, Shibata K, Matsuzaki M, Ibaraki K, Shimamoto Y, Tokunaga O (2000) B-cell lymphoma-associated hemophagocytic syndrome: clinicopathological characteristics. Ann Hematol 79:378-388
21. Murase T, Nakamura S, Kawauchi K, Matsuzaki H, Sakai C, Inaba T, Nasu K, Tashiro K, Suchi T, Saito H (2000) An Asian variant of intravascular large B-cell lymphoma: clinical, pathological and cytogenetic approaches to diffuse large B-cell lymphoma associated with haemophagocytic syndrome. Br J Hematol 111:826-834
22. Ohno T, Ueda Y, Nagai K, Takahashi T, Konaka Y, Takamatsu T, Suzuki T, Sasada M, Uchiyama T (2003) The serum cytokine profiles of lymphoma-associated hemophagocytic syndrome: a comparative analysis of B-cell and T-cell/Natural killer cell lymphomas. Int J Hematol 77:286-294
23. Chen R, Lowe L, Wilson JD, Crowther E, Tzeggai K, Bishop JE, Varro R (1999) Simultaneous quantification of six human cytokines in a single sample using microparticle-based flow cytometric technology. Clin Chem 45:1693-1694
24. Cook EB, Stahl JL, Lowe L, Chen R, Morgan E, Wilson J, Varro R, Chan A, Graziano FM, Barney NP (2001) Simultaneous measurement of six cytokines in a single sample of human tears using microparticle-based flow cytometry: allergics vs non-allergics. J Immunol Methods 254:109-118
25. Tárnok A, Hambsch J, Chen R, Varro R (2003) Cytometric bead array to measure six cytokines in twenty-five microliters of serum. Clin Chem 49:1000-1002
26. Morgan E, Varro R, Sepulveda H, Ember JA, Apgar J, Wilson J, Lowe L, Chen R, Shivraj L, Agadir A, Campos R, Ernst D, Gaur A (2004) Cytometric bead array: a multiplexed assay platform with applications in various areas of biology. Clin Immunol 110:252-266
27. Varro R, Chen R, Sepulveda H, Apgar J (2007) Bead-based multianalyte flow immunoassays: the cytometric bead array system. Methods Mol Biol 378:125-152
28. Fujii N, Hiraki A, Aoe K, Murakami T, Ikeda K, Masuda K, Matsuo K, Shinagawa K, Ishimaru F, Sugi K, Darzynkiewicz Z, Tanimoto M (2006) Serum cytokine concentrations and acute graft-versus-host disease after allogeneic peripheral blood stem cell transplantation: concurrent measurement of ten cytokines and their respective ratios using cytometric bead array. Int J Mol Med 17:881-885
29. Maier R, Weger M, Haller-Schober EM, EI-Shabrawi Y, Theisl A, Barth A, Aigner R, Haas A (2006) Application of multiplex cytometric bead array technology for the measurement of angiogenic factors in the vitreous. Mol Vis 12:1143-1147
30. Falasca K, Vecchiet F, Ucciferri C, Vignale F, Conti P, Pizzigallo A, Piatteli A, Vecchiet J (2008) Periodontitis and cytokine patterns in HIV positive patients. Eur J Med Res 13:163-168
31. Ichiyama T, Shoji H, Takahashi Y, Matsushige T, Kajimoto M, Inuzuka T, Furukawa S (2008) Cerebrospinal fluid levels of cytokines in non-herpetic acute limbic encephalitis: comparison with herpes simplex encephalitis. Cytokine 44:149-153
32. Tang Y, Liao C, Xu X, Song H, Shi S, Yang S, Zhao F, Xu W, Chen X, Mao J, Zhang L, Pan B (2011) Evaluation of Th1/Th2 cytokines as a rapid diagnostic tool for severe infection in paediatric haematology/oncology patients by the use of cytometric bead array technology. Clin Microbiol Infect 17:1666-1673
33. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (2008) WHO classification of tumours of haematopoietic and lymphoid tissues, 4th edn. Lyon, IARC
34. Pinsky MR, Vincent JL, Deviere J, Alegre M, Kahn RJ, Dupont E (1993) Serum cytokine levels in human septic shock. Relation to multiple-system organ failure and mortality. Chest 103:565-575
35. Bossink AW, Paemen L, Jansen PM, Hack CE, Thijs LG, Van Damme J (1995) Plasma levels of the chemokines monocyte chemotactic proteins-1 and -2 are elevated in human sepsis. Blood 86:3841-3847
36. Taniguchi T, Koido Y, Aiboshi J, Yamashita T, Suzaki S, Kurokawa A (1999) Change in the ratio of interleukin-6 to interleukin-10 predicts a poor outcome in patients with systemic inflammatory response syndrome. Crit Care Med 27:1262-1264
37. Bozza FA, Gomes RN, Japiassú AM, Soares M, Castro-Faria-Neto HC, Bozza PT, Bozza MT (2004) Macrophage migration inhibitory factor levels correlate with fatal outocome in sepsis. Shock 22:309-313
38. Oberholzer A, Souza SM, Tschoeke SK, Oberholzer C, Abouhamze A, Pribble JP, Moldawer LL (2005) Plasma cytokine measurements augment prognostic scores as indicator of outcome in patients with severe sepsis. Shock 23:488-493
39. Kellum JA, Kong L, Fink MP, Weissfeld LA, Yealy DM, Pinsky MR, Fine J, Krichevsky A, Delude RL, Angus DC (2007) Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study. Arch Intern Med 167:1655-1663
40. Luster AD, Unkeless JC, Ravetch JV (1985) Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins. Nature 315:672-676
41. Ohmori Y, Hamilton TA (1990) A macrophage LPS-inducible early gene encodes the murine homologue of IP-10. Biochem Biophys Res Commun 168:1261-1267
42. Farber JM (1992) A collection of mRNA species that are inducible in the RAW 264.7 mouse macrophage cell line by gamma interferon and other agents. Mol Cell Biol 12:1535-1545
43. Narumi S, Hamilton TA (1991) Inducible expression of murine IP-10 mRNA varies with the state of macrophage inflammation activity. J Immunol 146:3038-3044
44. Gasperini S, Marchi M, Calzetti F, Laudanna C, Vicentini L, Olsen H, Murphy M, Liao F, Farber J, Cassatella MA (1999) Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC) and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils. J Immunol 162:4928-4937
45. Yoneyama H, Narumi S, Zhang Y, Murai M, Baggiolini M, Lanzavecchia A, Ichida T, Asakura H, Matsushima K (2002) Pivotal role of dendritic cell-derived CXCL10 in the retention of T helper cell 1 lymphocytes in secondary lymph nodes. J Exp Med 195:1257-1266
46. Janatpour MJ, Hudak S, Sathe M, Sedgwick JD, McEvoy LM (2001) Tumor necrosis factor-dependent segmental control of MIG expression by high endothelial venules in inflamed lymph nodes regulates monocyte recruitment. J Exp Med 194:1375-1384
47. Bonecchi R, Bianchi G, Bordignon PP, D'Ambrosio D, Lang R, Borsatti A, Sozzani S, Allavena P, Gray PA, Mantovani A, Sinigaglia F (1998) Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med 187:129-134
48. Sallusto F, Lenig D, Mackay CR, Lanzavecchia A (1998) Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 187:875-883
49. Meyer M, Hensbergen PJ, van der Raaij-Helmer EM, Brandacher G, Margreiter R, Heufler C, Koch F, Narumi S, Werner ER, Colvin R, Luster AD, Tensen CP, Werner- Felmayer G (2001) Cross reactivity of three T cell attracting murine chemokines stimulating the CXC chemokine receptor CXCR3 and their induction in cultured cells and during allograft rejection. Eur J Immunol 31:2521-2527
50. Teruya-Feldstein J, Jaffe ES, Burd PR, Kingma DW, Setsuda JE, Tosato G (1999) Differential chemokine expression in tissues involved by Hodgkin's disease: direct correlation of eotaxin expression and tissue eosinophilia. Blood 93:2463-2470