Evaluation of homogeneity and genetic stability of REOLYSIN® (pelareorep) by complete genome sequencing of reovirus after large scale production

Applied Microbiology and Biotechnology

Volumn 98, Issue 4, 2014, Pages 1763-1770

  Chakrabarty, Romit ^a   Tran, Hue ^a   Fortin, Yves ^b   Yu, Zhenbao ^b   Shen, Shi Hsiang ^b   Kolman, John ^c   Onions, David ^c   Voyer, Robert ^b   Hagerman, Allison ^a   Serl, Sarah ^a   Kamen, Amine ^b   Thompson, Brad ^a   Coffey, Matt ^a  

^a ONCOLYTICS BIOTECH INC   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c BioReliance Corporation   (United States)

Author keywords

Genomics; Pelareorep; Phylogeny; REOLYSIN ; Reovirus; Sequencing

Indexed keywords

GENOME, VIRAL; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; PHYLOGENY; REOVIRIDAE;

EID: 84894380172     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-5499-0     Document Type: Article

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