The Moroccan Genetic Disease Database (MGDD): A database for DNA variations related to inherited disorders and disease susceptibility

European Journal of Human Genetics

Volumn 22, Issue 3, 2014, Pages 322-326

  Charoute, Hicham ^a,b   Nahili, Halima ^a   Abidi, Omar ^a   Gabi, Khalid ^a   Rouba, Hassan ^a   Fakiri, Malika ^b   Barakat, Abdelhamid ^a  

^a Institut Pasteur du Maroc   (Morocco)

^b Hassan 1st University   (Morocco)

Author keywords

database; genetic disorders; Morocco; mutations; polymorphisms

Indexed keywords

DATABASES, GENETIC; GENETIC DISEASES, INBORN; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MOROCCO; POLYMORPHISM, GENETIC;

EID: 84894355742     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2013.151     Document Type: Article

References (17)

1. Luo L, Boerwinkle E, Xiong M: Association studies for next-generation sequencing. Genome Res 2011; 21: 1099-1108.
2. Hamosh A, Scott AF, Amberger JS et al: Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res 2005; 33: D514-D517.
3. Stenson PD, Ball EV, Mort M et al: Cooper DN Human Gene Mutation Database (HGMD): 2003 update. Hum Mutat 2003; 21: 577-581.
4. Claustres M, Horaitis O, Vanevski M, Cotton RG: Time for a unified system of mutation description and reporting: a review of locus-specific mutation databases. Genome Res 2002; 12: 680-688.
5. Patrinos GP: National and ethnic mutation databases: recording populations' genography. Hum Mutat 2006; 27: 879-887.
6. Tadmouri GO, Al Ali MT, Al-Haj Ali S, Al Khaja N: CTGA: the database for genetic disorders in Arab populations. Nucleic Acids Res 2006; 34, Database issue D602-D606.
7. Megarbane A, Chouery E, van Baal S, Patrinos GP: The Lebanese National Mutation Frequency database. Eur J Hum Genet 2006; 14(Suppl 1): 365.
8. Tadmouri GO, Nair P, Obeid T, Al Ali MT, Al Khaja N, Hamamy HA: Consanguinity and reproductive health among Arabs. Reprod Health 2009; 6: 17.
9. Jaouad IC, Elalaoui SC, Sbiti A, Elkerh F, Belmahi L, Sefiani A: Consanguineous marriages in Morocco and the consequence for the incidence of autosomal recessive disorders. J Biosoc Sci 2009; 41: 575-581.
10. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM: Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127: 2893-2917.
11. Tazi MA, Abir-Khalil S, Chaouki N et al: Prevalence of the main cardiovascular risk factors in Morocco: results of a National Survey, 2000. J Hypertens 2003; 21: 897-903.
12. Wildeman M, van Ophuizen E, den Dunnen JT, Taschner PE: Improving sequence variant descriptions in mutation databases and literature using the Mutalyzer sequence variation nomenclature checker. Hum Mutat 2008; 29: 6-13.
13. Abidi O, Boulouiz R, Nahili H et al: The analysis of three markers flanking GJB2 gene suggests a single origin of the most common 35delG mutation in the Moroccan population. Biochem Biophys Res Commun 2008; 377: 971-974.
14. Soufir N, Ged C, Bourillon A et al: A prevalent mutation with founder effect in xeroderma pigmentosum group C from north Africa. J Invest Dermatol 2010; 130: 1537-1542.
15. Senhaji MA, Abidi O, Nadifi S et al: c.1643-1644delTG XPC mutation is more frequent in Moroccan patients with xeroderma pigmentosum. Arch Dermatol Res 2012; 305: 53-57.
16. Pastinen T, Perola M, Ignatius J et al: Dissecting a population genome for targeted screening of disease mutations. Hum Mol Genet 2001; 10: 2961-2972.
17. Romdhane L, Abdelhak S: Genetic diseases in the Tunisian population. Am J Med Genet A 2011; 155: 238-267.