Passive movement improves the learning and memory function of rats with cerebral infarction by inhibiting neuron cell apoptosis

Molecular Neurobiology

Volumn 49, Issue 1, 2014, Pages 216-221

  Li, Man ^a   Peng, Jun ^a   Wang, Meng Die ^a   Song, Yan Ling ^b   Mei, Yuan Wu ^a   Fang, Yuan ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Central Hospital   (China)

Author keywords

Bcl 2 mRNA; Caspase 3; Escape latency; Infarction; Passive movement

Indexed keywords

CASPASE 3; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; BRAIN INFARCTION; BRAIN NERVE CELL; BRAIN REGION; IMMUNOHISTOCHEMISTRY; LEARNING; MALE; MEMORY; MORRIS WATER MAZE TEST; NONHUMAN; PASSIVE MOVEMENT; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW;

ANIMALS; APOPTOSIS; CEREBRAL INFARCTION; EXERCISE THERAPY; LEARNING; MALE; MEMORY; MOVEMENT; NEURAL INHIBITION; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 84894308683     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-013-8512-9     Document Type: Review

References (24)

1. Lloyd-Jones D, Adams R et al (2009) Heart disease and stroke statistics - 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 119(3):480-486
2. Saxena SK, Ng TP et al (2007) Is improvement in impaired cognition and depressive symptoms in post-stroke patients associated with recovery in activities of daily living? Acta Neurol Scand 115(5):339-346
3. Tatemichi TK, Desmond DW et al (1992) Dementia after stroke: baseline frequency, risks, and clinical features in a hospitalized cohort. Neurology 42(6):1185-1193
4. Dromerick AW, Lang CE et al (2009) Very early constraint-induced movement during stroke rehabilitation (VECTORS): a single-center RCT. Neurology 73(3):195-201
5. Zhao S, Zhao M et al (2013) Constraint-induced movement therapy overcomes the intrinsic axonal growth-inhibitory signals in stroke rats. Stroke 44(6):1698-1705
6. Ang E-T, Dawe GS et al (2006) Alterations in spatial learning and memory after forced exercise. Brain Res 1113(1):186-193
7. Lou SJ, Liu JY et al (2008) Hippocampal neurogenesis and gene expression depend on exercise intensity in juvenile rats. Brain Res 1210:48-55
8. Radak Z, Toldy A et al (2006) The effects of training and detraining on memory, neurotrophins and oxidative stress markers in rat brain. Neurochem Int 49(4):387-392
9. van Praag H, Christie BR et al (1999) Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc Natl Acad Sci U S A 96(23):13427-13431
10. Liao W, Liu S et al (2002) Modification of the preparation of models of focal ischemic brain injury with suture occlusion in rats. Chin J Phys Med Rehabil 24(6):345-348
11. Longa EZ, Weinstein PR et al (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20:84-91
12. Houle JD, Morris K et al (1999) Effects of fetal spinal cord tissue transplants and cycling exercise on the soleus muscle in spinalized rats. Muscle Nerve 22:846-856
13. Petajan JH, Songster G et al (1981) Effects of passive movement on neurogenic atrophy in rabbit limb muscles. Exp Neurol 71:92-103
14. Morris R (1984) Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods 11(1):47-60
15. Okada M, Tamura A et al (1995) Long-term spatial cognitive impairment following middle cerebral artery occlusion in rats. A behavioral study. J Cereb Blood Flow Metab 15(3):505-512
16. Yonemori F, Yamada H et al (1996) Spatial memory disturbance after focal cerebral ischemia in rats. J Cereb Blood Flow Metab 16(5):973-980
17. Man LI, Peng J et al (2012) Electro-acupuncture combined with transcranial magnetic stimulation improves learning and memory function of rats with cerebral infarction by inhibiting neuron cell apoptosis. J Huazhong Univ Sci Technol Med Sci 32(5):746-749
18. Ni B, Wu X et al (1998) Transient global forebrain ischemia induces a prolonged expression of the caspase-3 mRNA in rat hippocampal CA1 pyramidal neurons. J Cereb Blood Flow Metab 18(3):248-256
19. Swanton E, Savory P et al (1999) Bcl-2 regulates a caspase-3/caspase-2 apoptotic cascade in cytosolic extracts. Oncogene 18(10):1781-1787
20. Zhang R, Xue Y-Y et al (2006) Bcl-2 enhances neurogenesis and inhibits apoptosis of newborn neurons in adult rat brain following a transient middle cerebral artery occlusion. Neurobiol Dis 24(2):345-356
21. Sim Y-J, Kim S-S et al (2004) Treadmill exercise improves short-term memory by suppressing ischemia-induced apoptosis of neuronal cells in gerbils. Neurosci Lett 372(3):256-261
22. Luo CX, Jiang J et al (2007) Voluntary exercise-induced neurogenesis in the postischemic dentate gyrus is associated with spatial memory recovery from stroke. J Neurosci Res 85(8):1637-1646
23. Zhang P, Yu H et al (2013) Early exercise improves cerebral blood flow through increased angiogenesis in experimental stroke rat model. J Neuroeng Rehabil 10:43
24. Ma Y, He M et al (2013) Exercise therapy downregulates the overexpression of TLR4, TLR2, MyD88 and NF-κB after cerebral ischemia in rats. Int J Mol Sci 14(2):3718-3733