Evaluation of the potential effect of transgenic rice expressing Cry1Ab on the hematology and enzyme activity in organs of female Swiss rats

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Wang, Yang ^a   Wei, Baoyang ^a   Tian, Yixing ^a   Wang, Zhi ^a   Yun Tian, Shuduan Tan ^a   Dong, Shengzhang ^b   Song, Qisheng ^a,b  

^a HUNAN AGRICULTURAL UNIVERSITY   (China)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL FEED; ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; BLOOD CHEMICAL ANALYSIS; CALCIUM; ENDOTOXINS; ENZYME ACTIVATION; FEMALE; FOOD, GENETICALLY MODIFIED; HEMOLYSIN PROTEINS; LIVER; LYMPHOCYTES; ORGAN SIZE; ORYZA SATIVA; PLANTS, GENETICALLY MODIFIED; RATS;

EID: 84894280333     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080424     Document Type: Article

References (33)

1. Sogawa K, Zhang H, Yang XJ, Liu GJ (2003) Whitebacked planthopper resistance in China rice varieties. Chinese Journal of Rice Science 17 (17): 47-52.
2. Breitler JC, Vassal JM, Catala MD, Meynard D, Marfa V, et al. (2004) Bt rice harbouring cry genes controlled by a constitutive or wound-inducible promoter: protection and transgene expression under Mediterraneanfield conditions. Plant Biotechnology Journal 2 (5): 417-430.
3. Ye GY, Shu QY, Yao HW, Cui HR, Cheng XY, et al. (2001) Field evaluation of resistance of transgenic rice containing a synthetic cry1Ab gene from Bacillus thuringiensis Berliner to two stem borers. Journal of Economic Entomology 94 (1): 271-276.
4. Bashir K, Husnain T, Fatima T, Latif Z, Mehdi SA, et al. (2004) Field evaluation and risk assessment of transgenic indica basmati rice. Molecular Breeding 13 (4): 301-312.
5. Ye RJ, Huang HQ, Yang Z, Chen TY, Liu L, et al. (2009) Development of insect-resistant transgenic rice with Cry1C*-free endosperm. Pest Management Science 65 (9): 1015-1020.
6. Zaidi MA, Ye GY, Yao HW, You TH, Loit E, et al. (2009) Transgenic rice plants expressing a modified cry1Ca1 gene are resistant to Spodoptera litura and Chilo suppressalis . Molecular Biotechnology 43 (3): 232-242.
7. Riaz N, Husnain T, Fatima T, Makhdoom R, Bashir K, et al. (2006) Development of Indica Basmati rice harboring two insecticidal genes for sustainable resistance against lepidopteran insects. South African Journal of Botany 72 (2): 217-223.
8. Chen H, Mang G, Zhang QF, Lin YJ (2008) Effect of transgenic Bacillus thuringiensis rice lines on mortality and feeding behavior of rice stem borers (Lepidoptera: Crambidae). Journal of Economic Entomology 101 (1): 182-189.
9. Ministry of Agriculture of the People's Republic of China (MAPRC) (2009) The second list of approval agricultural genetically modified organisms' safety certificates in 2009.
10. Chen M, Ye GY, Hu C, Datta SK (2003a) Effects of transgenic Bt indica rice on the feeding and oviposition behavior of the brown planthopper, Nilaparvata lugens. Acta Phytophylacica Sinica 30 (4): 365-370.
11. Chen M, Ye GY, Hu C, Tu J, Datta SK (2003b) Effect of transgenic Bt rice on dispersal of planthoppers and leafhoppers as well as their egg parasitic wasp. Journal of Zhejiang University (Agriculture & Life Sciences) 29 (1): 29-33.
12. Li FF, Ye GY, Wu Q, Peng YF, Chen XX (2007) Arthropod abundance and diversity in Bt and non-Bt rice fields. Environmental Entomology 36 (3): 646-654.
13. Chen M, Ye GY, Liu ZC, Yao HW, Chen XX, et al. (2006) Field assessment of the effects of transgenic rice expressing a fused gene of cry1Ab and cry1Ac from Bacillus thuringiensis Berliner on nontarget planthopper and leafhopper populations. Environmental Entomology 35 (1): 127-134.
14. Chen M, Liu ZC, Ye GY, Shen ZC, Hu C, et al. (2007) Impacts of transgenic cry1Ab rice on non-target planthoppers and their main predator Cyrtorhinus lividipennis (Hemiptera: Miridae) - A case study of the compatibility of Bt rice with biological control. Biological Control 42 (2): 242-250.
15. Bernal CC, Aguda RM, Cohen MB (2002) Effect of rice lines transformed with Bacillus thuringiensis toxin genes on the brown planthopper and its predator Cyrtorhinus lividipennis. Entomologia Experimentalis et Applicata 102 (1): 21-28.
16. Chen M, Ye GY, Lu XM, Hu C, Peng YF, et al. (2005) Biotransfer and bioaccumulation of Cry1Ab insecticidal protein in rice plant - brown planthopper - wolf spider food chain. Acta Entomologica Sinica, 48 (2): 208-213.
17. Bai YY, Jiang MX, Cheng JA, Wang D (2006) Effects of CrylAb toxin on Propylea japonica (Thunberg) (Coleoptera: Coccinellidae) through its prey, Nilaparvata lugens Stal (Homoptera: Delphacidae), feeding on transgenic Bt rice. Environmental Entomology 35 (4): 1130-1136.
18. Chen M, Gong Y, Liu ZC, Fanf Q, Hu C, et al. (2009) Analysis of Cry1Ab toxin bioaccumulation in a food chain of Bt rice, an herbivore and a predator. Ecotoxicology 18: 230-238.
19. Wang ZH, Wang Y, Cui HR, Xia YW, Altosaar I, et al. (2002) Toxilogical evaluation of transgenic rice flour with a synthetic Cry1Ab gene from Bacillus thuringiensis. Journal of the Science of Food and Agriculture 82: 738-744.
20. Schrøder M, Poulsen M, Wilcks A, Kroghsbo S, Miller A, et al. (2007) A 90-day safety study of genetically modified rice expressing Cry1Ab protein (Bacillus thuringiensis toxin) inWistar rats. Food and Chemical Toxicology 45 (3): 339-349.
21. Kroghsbo S, Madsen C, Poulsen M, Schrøder M, Kvist PH, et al. (2008) Immunotoxicological studies of genetically modified rice expressing PHA-E lectin or Bt toxin in Wistar rats. Toxicology 245 (1-2): 24-34.
22. Mesnage R, Clair E, Gress S, Then C, Székácsd A, et al. (2013) Cytotoxicity on human cells of Cry1Ab and Cry1Ac Bt insecticidal toxins alone or with a glyphosate-based herbicide. Journal of Applied Toxicology 33: 695-699.
23. Xu W, Cao S, He X, Luo Y, Guo X, et al. (2009) Safety assessment of Cry1Ab/Ac fusion protein 47 (7): 1459-65.
24. Gorun V, Proinov I, Baltescu V, Balaban G, Barzu O (1978) Modified Ellman procedure for assay of cholinesterases in crude enzymatic preparations. Analytical Biochemistry 86 (1): 324-6.
25. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using realtime quantitative PCR and the 2 DDC(T) Method. Methods 25(4): 402-408.
26. OECD (2004) Series on the safety of novel food and feed. No.10.Consensus document on compositional considerations for new varieties of rice (Oryza sativa): key food and feed nutrients and antinutrients.
27. Walsh MC, Buzoianu SG, Gardiner GE, Rea MC, Gelencsér E, et al. (2011) Fate of transgenic DNA from orally administered Bt MON810 maize and effects on immune response and growth in pigs. PLoS ONE 6 (11): e27177.
28. Chowdhury EH, Kuribara H, Hino A, Sultana P, Mikami O, et al. (2003a) Detection of corn intrinsic and recombinant DNA fragments and Cry1Ab protein in the gastrointestinal contents of pigs fed genetically modified corn Bt11. Journal of Animal Science 81 (10): 2546-2551.
29. Chowdhury EH, Shimada N, Murata H, Mikami O, Sultana P, et al. (2003b) Detection of Cry1Ab protein in gastrointestinal contents but not visceral organs of genetically modified Bt11-fed calves. Veterinary and Human Toxicology 45 (2): 72-75.
30. Aris A, Leblanc S (2011) Maternal and fetal exposure to pesticides associated to genetically modified foods in Eastern Townships of Quebec, Canada. Reproductive Toxicology 31(4): 528-33.
31. Walsh MC, Buzoianu SG, Rea MC, O'Donovan O, Gelencsér E, et al. (2012) Effects of feeding Bt MON810 maize to pigs for 110 days on peripheral immune response and digestive fate of the cry1Ab gene and truncated Bt toxin. PLoS ONE 7 (5): e36141.
32. Chubb IW, Pilowsky PM, Springell HJ, Pollard AC (1979) Acetylcholinesterase in human amniotic fluid: An index of fetal neural development? Lancet 1 (8118): 688-90.
33. Poinar GO Jr (1975) Description and biology of a new insect parasitic rhabditoid, Heterorhabditis bacteriophora n. n. gen. sp (Rhabditida; Heterorhabditidae n. fam). Nematologica 21: 463-470.