Effectiveness of co-trimoxazole to prevent plasmodium falciparum malaria in HIV-positive pregnant women in sub-saharan Africa: An open-label, randomized controlled trial

Clinical Infectious Diseases

Volumn 58, Issue 5, 2014, Pages 651-659

  Klement, Elise ^a   Pitché, Palokinam ^b   Kendjo, Eric ^c   Singo, Assétina ^b   D'Almeida, Stéphane ^b   Akouete, Folly ^d   Akpaloo, Yawo ^e   Tossa, Kokou ^f   Prince Agbodjan, Serge ^d   Patassi, Akouda ^b   Caumes, Eric ^c  

^a Centre Hospitalier de Bligny   (France)

^b Centre Hospitalo Universitaire   (Togo)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d AlterSanté ^*  (France)

^e Centre Hospitalier Préfectoral   (France)

^f Programme National de Lutte Contre le Paludisme   (Togo)

Author keywords

co trimoxazole; HIV positive pregnant women; P. falciparum malaria; randomized controlled trial; sub Saharan Africa

Indexed keywords

ANTIMALARIAL AGENT; COTRIMOXAZOLE; DRUG COMBINATION; FANASIL, PYRIMETHAMINE DRUG COMBINATION; PYRIMETHAMINE; SULFADOXINE;

ADOLESCENT; ADULT; CLINICAL TRIAL; COMPARATIVE STUDY; COMPLICATION; CONTROLLED STUDY; DRUG COMBINATION; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; MALARIA, FALCIPARUM; MULTICENTER STUDY; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC; RANDOMIZED CONTROLLED TRIAL; TOGO; TREATMENT OUTCOME; YOUNG ADULT;

ADOLESCENT; ADULT; ANTIMALARIALS; DRUG COMBINATIONS; FEMALE; HIV INFECTIONS; HUMANS; INCIDENCE; MALARIA, FALCIPARUM; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC; PYRIMETHAMINE; SULFADOXINE; TOGO; TREATMENT OUTCOME; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION; YOUNG ADULT;

EID: 84894246459     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cit806     Document Type: Article

References (31)

1. Klement E. Paludisme et infection par le VIH en Afrique subsaharienne. Mise au point. La Lettre de l'Infectiologue 2008; 23:42-9.
2. Ter Kuile FO, Parise ME, Verhoeff FH, et al. The burden of co-infection with human immunodeficiency virus type 1 and malaria in pregnant women in sub-saharan Africa. Am J Trop Med Hyg 2004; 71(2 suppl):41-54.
3. Brentlinger PE, Behrens CB, Micek MA. Challenges in the concurrent management of malaria and HIV in pregnancy in sub-Saharan Africa. Lancet Infect Dis 2006; 6:100-11.
4. World Health Organization. Integrated management of pregnancy and childbirth. Pregnancy, childbirth and postpartum care. A guide for essential practice. Geneva, Switzerland: WHO, 2006. Available at: http://whqlibdoc.who. int/publications/2006/924159084X-eng.pdf. Accessed 4 February 2013.
5. van Eijk AM, Nahlen BL, ter Kuile FO, et al. Effectiveness of intermittent preventive treatment with sulphadoxine-pyrimethamine for control of malaria in pregnancy in western Kenya: a hospital-based based study. Trop Med Int Health 2004; 9:651-60.
6. Programme National de Lutte contre le Paludisme. NLP. Rapport annuel d'activités 2010. Lomé, Togo: Direction Generale de la Sante Direction des Soins de Sante Primaires, 2010.
7. World Health Organization. Guidelines on co-trimoxazole prophylaxis for HIV-related infections among children, adolescents and adults. Recommendations for a public health approach 2006. Available at: http://www.who.int/hiv/pub/ guidelines/ctxguidelines.pdf. Accessed 4 February 2013.
8. Joint United Nations Programme on HIV/AIDS. Provisional WHO/UNAIDS Secretariat recommendations on the use of cotrimoxazole prophylaxis in adults and children living with HIV/AIDS in Africa, 2000. Available at: http://data.unaids.org/publications/IRC-pub04/recommendation-en.pdf. Accessed 4 February 2013.
9. Eliaszewicz M, Flahault A, Roujeau JC, Chosidow O, Caumes E. Prospective evaluation of risk factors of cutaneous drug reactions to sulfonamides in patients with AIDS. J Am Acad Dermatol 2002; 47:40-6.
10. Kamya MR, Gassasira AF, Achan J, et al. Effects of trimethoprimsulfamethoxazole and insecticide-treated bednets on malaria among HIV-infected Ugandan children. AIDS 2007; 21:2059-66.
11. Sandison TG, Homsy J, Arinaitwe E, et al. Protective efficacy of cotrimoxazole prophylaxis against malaria in HIV exposed children in rural Uganda: a randomised clinical trial. BMJ 2011; 342:d1617.
12. Mermin J, Ekwaru JP, Lietchy C, et al. Effect of co-trimoxazole prophylaxis, antiretroviral therapy, and insecticide-treated bednets on the frequency of malaria in HIV-1 infected adults in Uganda: a prospective cohort study. Lancet 2006; 367:1256-61.
13. WHO/Roll Back Malaria. Malaria and HIV interactions and their implications for public health policy. Report of a technical consultation. Geneva, Switzerland: WHO, 2005. Available at: http://whqlibdoc.who. int/publications/2005/9241593350.pdf. Accessed 4 February 2013.
14. Kapito-Tembo A, Meshnick SR, van Hensbroek MB, Phiri K, Fitzgerald MMwapasa V. Marked reduction in prevalence of malaria parasitemia and anemia in HIV-infected pregnant women taking cotrimoxazole with or without sulfadoxine-pyrimethamine intermittent preventive therapy during pregnancy in Malawi. J Infect Dis 2011; 203: 464-72.
15. Runsewe-Abiodun I, Ogunfowora O, Fetuga B. Neonatal malaria in Nigeria-a 2 year review. BMC Pediatrics 2006; 6:19.
16. Campbell JD, Moore D, Degerman R, et al. HIV-infected Ugandan adults taking antiretroviral therapy with CD4 counts 200 cells/μL who discontinue cotrimoxazole prophylaxis have increased risk of malaria and diarrhea. Clin Infect Dis 2012; 54:1204-11.
17. World Health Organization. World malaria report 2012. Malaria country profiles. Togo: African Region. Available at: http://www.who. int/malaria/publications/country-profiles/profile-tgo-en.pdf. Accessed 4 February 2013.
18. Eliades MJ, Wolkon A, Morgah K, et al. Burden of malaria at community level in children less than 5 years of age in Togo. Am J Trop Med Hyg 2006; 75:622-9.
19. World Health Organization. Global report on antimalarial drug efficacy and drug resistance: 2000-2010. Available at: http://whqlibdoc.who.int/ publications/2010/9789241500470-eng.pdf. Accessed 4 February 2013.
20. Iyer JK, Milhous WK, Cortese JF, Kublin JG, Plowe CV. Plasmodium falciparum cross-resistance between trimethoprim and pyrimethamine. Lancet 2001; 358:1066-7.
21. Iriemenam NC, Shah M, Gatei W, et al. Temporal trends of sulphadoxine-pyrimethamine (SP) drug-resistance molecular markers in Plasmodium falciparum parasites from pregnant women in western Kenya. Malar J 2012; 11:134.
22. Cottrell G, Mary JY, Barro D, Cot M. Is malarial placental infection related to peripheral infection at any time of pregnancy? Am J Trop Med Hyg 2005; 73:1112-18.
23. van Eijk AM, Ayisi JG, Ter Kuile FO, et al. HIV, malaria, and infant anaemia as risk factors for postneonatal infant mortality among HIVseropositive women in Kisumu, Kenya. J Infect Dis 2007; 196:30-7.
24. Newman PM, Wanzira H, Tumwine G, et al. Placental malaria among HIV-infected and uninfected women receiving anti-folates in a high transmission area of Uganda. Malar J 2009; 8:254.
25. Nkhoma ET, Kalilani-Phiri L, Mwapasa V, Rogerson SJ, Meshnick SR. Effect of HIV infection and Plasmodium falciparum parasitemia on pregnancy outcomes in Malawi. Am J Trop Med Hyg 2012; 87:29-34.
26. Walter J, Mwiya M, Scott N, et al. Reduction in preterm delivery and neonatal mortality after the introduction of antenatal cotrimoxazole prophylaxis among HIV-infected women with low CD4 cell counts. J Infect Dis 2006; 194:1510-8.
27. Msamanga GI, Taha ET, Young AM, et al. Placental malaria and mother-to-child transmission of human immunodeficiency virus-1. Am J Trop Med Hyg 2009; 80:508-15.
28. Villamor E, Msamanga G, Aboud S, Urassa W, Hunter DJ, Fawzi WW. Adverse perinatal outcomes of HIV1infected women in relation to malaria parasitemia in maternal and umbilical cord blood. Am J Trop Med Hyg 2005; 73:694-7.
29. Naniche D, Lahuerta M, Bardaji A, et al. Mother-to-child transmission of HIV-1: association with malaria prevention, anaemia and placental malaria. HIV Med 2008; 9:757-64.
30. Bulterys PL, Chao A, Dalai SC, et al. Placental malaria and motherto-child transmission of human immunodeficiency virus-1 in rural Rwanda. Am J Trop Med Hyg 2011; 85:202-6.
31. Ter Kuile FO, Steketee RW, Hamer DH, et al. Two-dose versus monthly intermittent preventive treatment of malaria with sulfadoxinepyrimethamine in HIV-seropositive pregnant Zambian women. J Infect Dis 2007; 196:1574-6, 1585-94.