-
3
-
-
79960949865
-
Dermatological side effects of current and upcoming targeted therapies in oncology
-
Bonny M, Buyse V, Brochez L. Dermatological side effects of current and upcoming targeted therapies in oncology. Acta Clin Belg 2011; 66: 97-103.
-
(2011)
Acta Clin Belg
, vol.66
, pp. 97-103
-
-
Bonny, M.1
Buyse, V.2
Brochez, L.3
-
5
-
-
21344462378
-
Cutaneous side-effects of kinase inhibitors and blocking antibodies
-
Robert C, Soria JC, Spatz A, et al. Cutaneous side-effects of kinase inhibitors and blocking antibodies. Lancet Oncol 2005; 6: 491-500.
-
(2005)
Lancet Oncol
, vol.6
, pp. 491-500
-
-
Robert, C.1
Soria, J.C.2
Spatz, A.3
-
6
-
-
71949112710
-
Cutaneous adverse effects in patients treated with the multitargeted kinase inhibitors sorafenib and sunitinib
-
Lee WJ, Lee JL, Chang SE, et al. Cutaneous adverse effects in patients treated with the multitargeted kinase inhibitors sorafenib and sunitinib. Br J Dermatol 2009; 161: 1045-1051.
-
(2009)
Br J Dermatol
, vol.161
, pp. 1045-1051
-
-
Lee, W.J.1
Lee, J.L.2
Chang, S.E.3
-
7
-
-
80051798682
-
The emergence of supportive oncodermatology: the study of dermatologic adverse events to cancer therapies
-
Balagula Y, Rosen ST, Lacouture ME. The emergence of supportive oncodermatology: the study of dermatologic adverse events to cancer therapies. J Am Acad Dermatol 2011; 65: 624-635.
-
(2011)
J Am Acad Dermatol
, vol.65
, pp. 624-635
-
-
Balagula, Y.1
Rosen, S.T.2
Lacouture, M.E.3
-
8
-
-
0035724536
-
Cutaneous side-effects in cancer patients treated with the antiepidermal growth factor receptor antibody C225
-
Busam KJ, Capodieci P, Motzer R, et al. Cutaneous side-effects in cancer patients treated with the antiepidermal growth factor receptor antibody C225. Br J Dermatol 2001; 144: 1169-1176.
-
(2001)
Br J Dermatol
, vol.144
, pp. 1169-1176
-
-
Busam, K.J.1
Capodieci, P.2
Motzer, R.3
-
9
-
-
77956252220
-
Histopathologic and immunohistochemical characterization of rash to human epidermal growth factor receptor 1 (HER1) and HER1/2 inhibitors in cancer patients
-
Nardone B, Nicholson K, Newman M, et al. Histopathologic and immunohistochemical characterization of rash to human epidermal growth factor receptor 1 (HER1) and HER1/2 inhibitors in cancer patients. Clin Cancer Res 2010; 16: 4452-4460.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4452-4460
-
-
Nardone, B.1
Nicholson, K.2
Newman, M.3
-
10
-
-
80052748563
-
Phase II study of cetuximab as first-line single-drug therapy in patients with unresectable squamous cell carcinoma of the skin
-
Maubec E, Petrow P, Scheer-Senyarich I, et al. Phase II study of cetuximab as first-line single-drug therapy in patients with unresectable squamous cell carcinoma of the skin. J Clin Oncol 2011; 29: 3419-3426.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3419-3426
-
-
Maubec, E.1
Petrow, P.2
Scheer-Senyarich, I.3
-
11
-
-
33746920516
-
Description and management of cutaneous side effects during cetuximab or erlotinib treatments: a prospective study of 30 patients
-
Roe E, Garcia Muret MP, Marcuello E, et al. Description and management of cutaneous side effects during cetuximab or erlotinib treatments: a prospective study of 30 patients. J Am Acad Dermatol 2006; 55: 429-437.
-
(2006)
J Am Acad Dermatol
, vol.55
, pp. 429-437
-
-
Roe, E.1
Garcia Muret, M.P.2
Marcuello, E.3
-
12
-
-
79960059394
-
Adverse cutaneous reactions to epidermal growth factor receptor inhibitors: a study of 14 patients
-
Santiago F, Goncalo M, Reis JP, et al. Adverse cutaneous reactions to epidermal growth factor receptor inhibitors: a study of 14 patients. An Bras Dermatol 2011; 86: 483-490.
-
(2011)
An Bras Dermatol
, vol.86
, pp. 483-490
-
-
Santiago, F.1
Goncalo, M.2
Reis, J.P.3
-
13
-
-
37849008220
-
Markers in the epidermal growth factor receptor pathway and skin toxicity during erlotinib treatment
-
Tan AR, Steinberg SM, Parr AL, et al. Markers in the epidermal growth factor receptor pathway and skin toxicity during erlotinib treatment. Ann Oncol 2008; 19: 185-190.
-
(2008)
Ann Oncol
, vol.19
, pp. 185-190
-
-
Tan, A.R.1
Steinberg, S.M.2
Parr, A.L.3
-
14
-
-
37349121157
-
Erlotinib-induced florid acneiform rash complicated by extensive impetiginization
-
Kardaun SH, Van Duinen KF. Erlotinib-induced florid acneiform rash complicated by extensive impetiginization. Clin Exp Dermatol 2008; 33: 46-49.
-
(2008)
Clin Exp Dermatol
, vol.33
, pp. 46-49
-
-
Kardaun, S.H.1
Van Duinen, K.F.2
-
15
-
-
84857501696
-
Efficacy and safety of erlotinib versus chemotherapy in second-line treatment of patients with advanced, non-small-cell lung cancer with poor prognosis (TITAN): a randomised multicentre, open-label, phase 3 study
-
Ciuleanu T, Stelmakh L, Cicenas S, et al. Efficacy and safety of erlotinib versus chemotherapy in second-line treatment of patients with advanced, non-small-cell lung cancer with poor prognosis (TITAN): a randomised multicentre, open-label, phase 3 study. Lancet Oncol 2012; 13: 300-308.
-
(2012)
Lancet Oncol
, vol.13
, pp. 300-308
-
-
Ciuleanu, T.1
Stelmakh, L.2
Cicenas, S.3
-
16
-
-
74349087063
-
Erlotinib 150 mg daily plus chemotherapy in advanced pancreatic cancer: an interim safety analysis of a multicenter, randomized, cross-over phase III trial of the 'Arbeitsgemeinschaft Internistische Onkologie'
-
Boeck S, Vehling-Kaiser U, Waldschmidt D, et al. Erlotinib 150 mg daily plus chemotherapy in advanced pancreatic cancer: an interim safety analysis of a multicenter, randomized, cross-over phase III trial of the 'Arbeitsgemeinschaft Internistische Onkologie'. Anticancer Drugs 2010; 21: 94-100.
-
(2010)
Anticancer Drugs
, vol.21
, pp. 94-100
-
-
Boeck, S.1
Vehling-Kaiser, U.2
Waldschmidt, D.3
-
17
-
-
79959283388
-
Multi-institutional phase II study of selumetinib in patients with metastatic biliary cancers
-
Bekaii-Saab T, Phelps MA, Li X, et al. Multi-institutional phase II study of selumetinib in patients with metastatic biliary cancers. J Clin Oncol 2011; 29: 2357-2363.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2357-2363
-
-
Bekaii-Saab, T.1
Phelps, M.A.2
Li, X.3
-
18
-
-
80755177739
-
Dermatologic side effects associated with the MEK 1/2 inhibitor selumetinib (AZD6244, ARRY-142886)
-
Balagula Y, Barth Huston K, Busam KJ, et al. Dermatologic side effects associated with the MEK 1/2 inhibitor selumetinib (AZD6244, ARRY-142886). Invest New Drugs 2011; 29: 1114-1121.
-
(2011)
Invest New Drugs
, vol.29
, pp. 1114-1121
-
-
Balagula, Y.1
Barth Huston, K.2
Busam, K.J.3
-
19
-
-
76649090958
-
Case studies showing clinical signs and management of cutaneous toxicity of the MEK1/2 inhibitor AZD6244 (ARRY-142886) in patients with solid tumours
-
Desar IM, Bovenschen HJ, Timmer-Bonte AJ, et al. Case studies showing clinical signs and management of cutaneous toxicity of the MEK1/2 inhibitor AZD6244 (ARRY-142886) in patients with solid tumours. Acta Oncol 2010; 49: 110-113.
-
(2010)
Acta Oncol
, vol.49
, pp. 110-113
-
-
Desar, I.M.1
Bovenschen, H.J.2
Timmer-Bonte, A.J.3
-
20
-
-
78751481518
-
Disseminated follicular eruption during therapy with the MEK inhibitor AZD6244
-
Querfeld C, Duffy K, Magel G, et al. Disseminated follicular eruption during therapy with the MEK inhibitor AZD6244. J Am Acad Dermatol 2011; 64: e17-19.
-
(2011)
J Am Acad Dermatol
, vol.64
-
-
Querfeld, C.1
Duffy, K.2
Magel, G.3
-
21
-
-
47849105015
-
Prospective study of the cutaneous adverse effects of sorafenib, a novel multikinase inhibitor
-
Autier J, Escudier B, Wechsler J, et al. Prospective study of the cutaneous adverse effects of sorafenib, a novel multikinase inhibitor. Arch Dermatol 2008; 144: 886-892.
-
(2008)
Arch Dermatol
, vol.144
, pp. 886-892
-
-
Autier, J.1
Escudier, B.2
Wechsler, J.3
-
22
-
-
39049121694
-
Hand-foot skin reaction in patients treated with sorafenib: a clinicopathological study of cutaneous manifestations due to multitargeted kinase inhibitor therapy
-
Yang CH, Lin WC, Chuang CK, et al. Hand-foot skin reaction in patients treated with sorafenib: a clinicopathological study of cutaneous manifestations due to multitargeted kinase inhibitor therapy. Br J Dermatol 2008; 158: 592-596.
-
(2008)
Br J Dermatol
, vol.158
, pp. 592-596
-
-
Yang, C.H.1
Lin, W.C.2
Chuang, C.K.3
-
23
-
-
58149345018
-
Dermatologic symptoms associated with the multikinase inhibitor sorafenib
-
Robert C, Mateus C, Spatz A, et al. Dermatologic symptoms associated with the multikinase inhibitor sorafenib. J Am Acad Dermatol 2009; 60: 299-305.
-
(2009)
J Am Acad Dermatol
, vol.60
, pp. 299-305
-
-
Robert, C.1
Mateus, C.2
Spatz, A.3
-
24
-
-
79952765808
-
Sorafenib-induced premalignant and malignant skin lesions
-
Williams VL, Cohen PR, Stewart DJ. Sorafenib-induced premalignant and malignant skin lesions. Int J Dermatol 2011; 50: 396-402.
-
(2011)
Int J Dermatol
, vol.50
, pp. 396-402
-
-
Williams, V.L.1
Cohen, P.R.2
Stewart, D.J.3
-
25
-
-
84855435059
-
Skin tumors induced by sorafenib; paradoxic RAS-RAF pathway activation and oncogenic mutations of HRAS, TP53, and TGFBR1
-
Arnault JP, Mateus C, Escudier B, et al. Skin tumors induced by sorafenib; paradoxic RAS-RAF pathway activation and oncogenic mutations of HRAS, TP53, and TGFBR1. Clin Cancer Res 2012; 18: 263-272.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 263-272
-
-
Arnault, J.P.1
Mateus, C.2
Escudier, B.3
-
26
-
-
65249127575
-
Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib
-
Dubauskas Z, Kunishige J, Prieto VG, et al. Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib. Clinical Genitourinary Cancer 2009; 7: 20-23.
-
(2009)
Clinical Genitourinary Cancer
, vol.7
, pp. 20-23
-
-
Dubauskas, Z.1
Kunishige, J.2
Prieto, V.G.3
-
27
-
-
84856071447
-
Phase I, dose-escalation study of BKM120, an oral pan-class I PI3K inhibitor, in patients with advanced solid tumors
-
Bendell JC, Rodon J, Burris HA, et al. Phase I, dose-escalation study of BKM120, an oral pan-class I PI3K inhibitor, in patients with advanced solid tumors. J Clin Oncol 2011; 30: 282-290.
-
(2011)
J Clin Oncol
, vol.30
, pp. 282-290
-
-
Bendell, J.C.1
Rodon, J.2
Burris, H.A.3
-
28
-
-
83255162603
-
First-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors
-
Yap TA, Yan L, Patnaik A, et al. First-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors. J Clin Oncol 2011; 29: 4688-4695.
-
(2011)
J Clin Oncol
, vol.29
, pp. 4688-4695
-
-
Yap, T.A.1
Yan, L.2
Patnaik, A.3
-
29
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 0000; 364: 2507-2516.
-
(0)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
30
-
-
84864340896
-
Safety, pharmacokinetic, pharmacodynamic, and efficacy data for the oral MEK inhibitor trametinib: a phase 1 dose-escalation trial
-
Infante JR, Fecher LA, Falchook GS, et al. Safety, pharmacokinetic, pharmacodynamic, and efficacy data for the oral MEK inhibitor trametinib: a phase 1 dose-escalation trial. Lancet Oncol 2012; 13: 773-781.
-
(2012)
Lancet Oncol
, vol.13
, pp. 773-781
-
-
Infante, J.R.1
Fecher, L.A.2
Falchook, G.S.3
-
31
-
-
68849111836
-
The histologic spectrum of epithelial neoplasms induced by sorafenib
-
Kwon EJ, Kish LS, Jaworsky C. The histologic spectrum of epithelial neoplasms induced by sorafenib. J Am Acad Dermato 2009; 61: 522-527.
-
(2009)
J Am Acad Dermato
, vol.61
, pp. 522-527
-
-
Kwon, E.J.1
Kish, L.S.2
Jaworsky, C.3
-
32
-
-
78751622165
-
Clinical presentation and management of dermatological toxicities of epidermal growth factor receptor inhibitors
-
Balagula Y, Garbe C, Myskowski PL, et al. Clinical presentation and management of dermatological toxicities of epidermal growth factor receptor inhibitors. Int J Dermatol 2011; 50: 129-146.
-
(2011)
Int J Dermatol
, vol.50
, pp. 129-146
-
-
Balagula, Y.1
Garbe, C.2
Myskowski, P.L.3
-
33
-
-
80052755557
-
Cutaneous toxicities of the multikinase inhibitors sorafenib and sunitinib
-
McLellan B, Kerr H. Cutaneous toxicities of the multikinase inhibitors sorafenib and sunitinib. Dermatol Ther 2011; 24: 396-400.
-
(2011)
Dermatol Ther
, vol.24
, pp. 396-400
-
-
McLellan, B.1
Kerr, H.2
-
34
-
-
84856007023
-
Radiation-induced increase in cell migration and metastatic potential of cervical cancer cells operates via the K-Ras pathway
-
Su WH, Chuang PC, Huang EY, et al. Radiation-induced increase in cell migration and metastatic potential of cervical cancer cells operates via the K-Ras pathway. Am J Pathol 2012; 180: 862-871.
-
(2012)
Am J Pathol
, vol.180
, pp. 862-871
-
-
Su, W.H.1
Chuang, P.C.2
Huang, E.Y.3
-
35
-
-
67349083594
-
Skin toxicities associated with epidermal growth factor receptor inhibitors
-
Li T, Perez-Soler R. Skin toxicities associated with epidermal growth factor receptor inhibitors. Target Oncol 2009; 4: 107-119.
-
(2009)
Target Oncol
, vol.4
, pp. 107-119
-
-
Li, T.1
Perez-Soler, R.2
-
36
-
-
24044500971
-
Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors
-
Segaert S, van Cutsem E. Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors. Ann Oncol 2005; 16: 1425-1433.
-
(2005)
Ann Oncol
, vol.16
, pp. 1425-1433
-
-
Segaert, S.1
van Cutsem, E.2
-
37
-
-
84863234102
-
Selumetinib (AZD6244; ARRY-142886) in the treatment of metastatic melanoma
-
Patel SP, Kim KB. Selumetinib (AZD6244; ARRY-142886) in the treatment of metastatic melanoma. Expert Opin Investig Drugs 2012; 21: 531-539.
-
(2012)
Expert Opin Investig Drugs
, vol.21
, pp. 531-539
-
-
Patel, S.P.1
Kim, K.B.2
-
38
-
-
79952261716
-
GSK1120212 (JTP-74057) is an inhibitor of MEK activity and activation with favorable pharmacokinetic properties for sustained in vivo pathway inhibition
-
Gilmartin AG, Bleam MR, Groy A, et al. GSK1120212 (JTP-74057) is an inhibitor of MEK activity and activation with favorable pharmacokinetic properties for sustained in vivo pathway inhibition. Clin Cancer Res 2011; 17: 989-1000.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 989-1000
-
-
Gilmartin, A.G.1
Bleam, M.R.2
Groy, A.3
-
39
-
-
79952805490
-
Novel agents in the management of pancreatic adenocarcinoma: phase I studies. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium"
-
San Francisco, CA, USA. January 20-22, 2011
-
Dimou AT, Syrigos KN, Saif MW. Novel agents in the management of pancreatic adenocarcinoma: phase I studies. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011 JOP 2011; 12: 114-116.
-
(2011)
JOP
, vol.12
, pp. 114-116
-
-
Dimou, A.T.1
Syrigos, K.N.2
Saif, M.W.3
-
40
-
-
84864371119
-
Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial
-
Falchook GS, Lewis KD, Infante JR, et al. Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial. Lancet Oncol 2012; 13: 782-789.
-
(2012)
Lancet Oncol
, vol.13
, pp. 782-789
-
-
Falchook, G.S.1
Lewis, K.D.2
Infante, J.R.3
-
41
-
-
79955960147
-
Meta-analysis of dermatological toxicities associated with sorafenib
-
Zhang L, Zhou Q, Ma L, et al. Meta-analysis of dermatological toxicities associated with sorafenib. Clin Exp Dermatol 2011; 36: 344-350.
-
(2011)
Clin Exp Dermatol
, vol.36
, pp. 344-350
-
-
Zhang, L.1
Zhou, Q.2
Ma, L.3
-
42
-
-
70449647041
-
Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib
-
Lipworth AD, Robert C, Zhu AX. Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib. Oncology 2009; 77: 257-271.
-
(2009)
Oncology
, vol.77
, pp. 257-271
-
-
Lipworth, A.D.1
Robert, C.2
Zhu, A.X.3
-
43
-
-
45349101568
-
Multiple squamous cell carcinomas of the skin after therapy with sorafenib combined with tipifarnib
-
Hong DS, Reddy SB, Prieto VG, et al. Multiple squamous cell carcinomas of the skin after therapy with sorafenib combined with tipifarnib. Arch Dermatol 2008; 144: 779-782.
-
(2008)
Arch Dermatol
, vol.144
, pp. 779-782
-
-
Hong, D.S.1
Reddy, S.B.2
Prieto, V.G.3
-
44
-
-
0033179479
-
Paradoxical activation of Raf by a novel Raf inhibitor
-
Hall-Jackson CA, Eyers PA, Cohen P, et al. Paradoxical activation of Raf by a novel Raf inhibitor. Chem Biol 1999; 6: 559-568.
-
(1999)
Chem Biol
, vol.6
, pp. 559-568
-
-
Hall-Jackson, C.A.1
Eyers, P.A.2
Cohen, P.3
-
45
-
-
84862908097
-
RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors
-
Su F, Viros A, Milagre C, et al. RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors. N Engl J Med 2012; 366: 207-215.
-
(2012)
N Engl J Med
, vol.366
, pp. 207-215
-
-
Su, F.1
Viros, A.2
Milagre, C.3
-
46
-
-
84856067754
-
Induction of cutaneous squamous cell carcinomas by RAF inhibitors: cause for concern?
-
Lacouture ME, O'Reilly K, Rosen N, et al. Induction of cutaneous squamous cell carcinomas by RAF inhibitors: cause for concern? J Clin Oncol 2012; 30: 329-330.
-
(2012)
J Clin Oncol
, vol.30
, pp. 329-330
-
-
Lacouture, M.E.1
O'Reilly, K.2
Rosen, N.3
-
47
-
-
84862908526
-
RAS mutations are associated with the development of cutaneous squamous cell tumors in patients treated with RAF Inhibitors
-
Oberholzer PA, Kee D, Dziunycz P, et al. RAS mutations are associated with the development of cutaneous squamous cell tumors in patients treated with RAF Inhibitors. J Clin Oncol 2012; 30: 316-321.
-
(2012)
J Clin Oncol
, vol.30
, pp. 316-321
-
-
Oberholzer, P.A.1
Kee, D.2
Dziunycz, P.3
-
48
-
-
79953072406
-
Partial recessive IFN-gammaR1 deficiency: genetic, immunological and clinical features of 14 patients from 11 kindreds
-
Sologuren I, Boisson-Dupuis S, Pestano J, et al. Partial recessive IFN-gammaR1 deficiency: genetic, immunological and clinical features of 14 patients from 11 kindreds. Hum Mol Genet 2011; 20: 1509-1523.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 1509-1523
-
-
Sologuren, I.1
Boisson-Dupuis, S.2
Pestano, J.3
-
49
-
-
77955902713
-
Refractory aggressive keratoacanthoma centrifugum marginatum of the scalp controlled with the epidermal growth factor receptor inhibitor erlotinib
-
Bulj TK, Krunic AL, Cetner AS, et al. Refractory aggressive keratoacanthoma centrifugum marginatum of the scalp controlled with the epidermal growth factor receptor inhibitor erlotinib. Br J Dermatol 2010; 163: 633-637.
-
(2010)
Br J Dermatol
, vol.163
, pp. 633-637
-
-
Bulj, T.K.1
Krunic, A.L.2
Cetner, A.S.3
|