Novel chemotherapeutic strategies in the management of primary amoebic meningoencephalitis due to Naegleria fowleri

CNS Neuroscience and Therapeutics

Volumn 20, Issue 3, 2014, Pages 289-290

  Baig, Abdul M ^a   Khan, Naveed A ^a  

^a AGA KHAN UNIVERSITY   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

AMEBIASIS; ANTIPARASITIC AGENTS; CENTRAL NERVOUS SYSTEM PROTOZOAL INFECTIONS; DRUG DELIVERY SYSTEMS; HUMANS; NAEGLERIA FOWLERI;

EID: 84894228911     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12225     Document Type: Letter

References (10)

1. Vargas-Zepeda J, Gomez-Alcala AV, Vasquez-Morales JA, Licea-Amaya L, De Jonckheere JF, Lores-Villa F. Successful treatment of Naegleria PAM using IV amphotericin B, fluconazole, and rifampin. Arch Med Res 2005;36:83-86.
2. Maclean RC, Richardson DJ, LePardo R, Marciano-Cabral F. The identification of Naegleria fowleri from water and soil samples by nested PCR. Parasitol Res 2004;93:211-217.
3. Marciano-Cabral F, Cabral G. The immune response to Naegleria fowleri amebae and pathogenesis of infection. FEMS Immunol Med Microbiol 2007;51:243-259.
4. Visvesvara GS, Moura H, Schuster FL. Pathogenic and opportunistic free-living amoebae: Acanthamoeba spp., Balamuthia mandrillaris, Naegleria fowleri, and Sappinia diploidea. FEMS Immunol Med Microbiol 2007;50:1-26.
5. Seidel JS, Harmatz P, Visvesvara GS, Cohen A, Edwards J, Turner J. Successful treatment of primary amebic meningoencephalitis. N Engl J Med 1982;306:346.
6. Schuster FL, Guglielmo BJ, Visvesvara GS. In vitro activity of miltefosine and voriconazole on clinical isolates of free-living amebas: Balamuthia mandrillaris, Acanthamoeba spp., and Naegleria fowleri. J Eukaryot Microbiol 2006;53:121-126.
7. Centers for Disease Control and Prevention (CDC). Primary amebic meningoencephalitis - Arizona, Florida, and Texas, 2007. Morb Mortal Wkly Rep 2008;57:573-577.
8. Atkinson AJ Jr, Bennett JE. Amphotericin B pharmacokinetics in humans. Antimicrob Agents Chemother 1978;13:271-276.
9. Wen MM. Olfactory targeting through intranasal delivery. Discov Med 2011;11:497-503.
10. Baig AM, Iqbal J, Khan NA. In vitro efficacy of clinically available drugs against growth and viability of Acanthamoeba castellanii. Antimicrob Agents Chemother 2013;57:3561-3567.