Acamprosate: An alcoholism treatment that may not be what we thought

Neuropsychopharmacology

Volumn 39, Issue 4, 2014, Pages 781-782

  Heilig, Markus ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DETERRENTS; ALCOHOLISM; ANIMALS; CALCIUM; HUMANS; MALE; TAURINE;

EID: 84894165274     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.272     Document Type: Note

References (6)

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2. Mason BJ, Lehert P (2012). Acamprosate for alcohol dependence: a sex-specific meta-analysis based on individual patient data. Alcohol Clin Exp Res 36: 497-508.
3. Rimondini R, Arlinde C, Sommer W, Heilig M (2002). Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol. FASEB J 16: 27-35.
4. Spanagel R, Pendyala G, Abarca C, Zghoul T, Sanchis-Segura C, Magnone MC et al (2005). The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption. Nat Med 11: 35-42.
5. Spanagel R, Vengeliene V, Jandeleit B, Fischer WF, Grindstaff K, Zhang X et al (2013). Acamprosate produces its anti-relapse effects via calcium. Neuropsychopharmacology.
6. Umhau JC, Momenan R, Schwandt ML, Singley E, Lifshitz M, Doty L et al (2010). Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study. Arch Gen Psychiatry 67: 1069-1077.