메뉴 건너뛰기




Volumn 8, Issue 11, 2013, Pages

Evaluation of OspA vaccination-induced serological correlates of protection against Lyme borreliosis in a mouse model

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, SURFACE; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL VACCINES; BORRELIA BURGDORFERI; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; IMMUNOGLOBULIN G; LIPOPROTEINS; LYME DISEASE; LYME DISEASE VACCINES; MICE; VACCINATION;

EID: 84894146944     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079022     Document Type: Article
Times cited : (10)

References (41)
  • 5
    • 79952721915 scopus 로고    scopus 로고
    • The expanding Lyme Borrelia complex-clinical significance of genomic species?
    • Stanek G, Reiter M (2011) The expanding Lyme Borrelia complex-clinical significance of genomic species? Clin Microbiol Infect 17: 487-493.
    • (2011) Clin Microbiol Infect , vol.17 , pp. 487-493
    • Stanek, G.1    Reiter, M.2
  • 9
    • 79952591597 scopus 로고    scopus 로고
    • Relationship between immunity to Borrelia burgdorferi outer-surface protein A (OspA) and Lyme arthritis
    • Steere AC, Drouin EE, Glickstein LJ (2011) Relationship between immunity to Borrelia burgdorferi outer-surface protein A (OspA) and Lyme arthritis. Clin Infect Dis 52 Suppl 3: s259-s265.
    • (2011) Clin Infect Dis , vol.52 , Issue.SUPPL. 3
    • Steere, A.C.1    Drouin, E.E.2    Glickstein, L.J.3
  • 10
    • 79952543170 scopus 로고    scopus 로고
    • Correcting a public health fiasco: The need for a new vaccine against Lyme disease
    • Plotkin SA (2011) Correcting a public health fiasco: The need for a new vaccine against Lyme disease. Clin Infect Dis 52 Suppl 3: s271-s275.
    • (2011) Clin Infect Dis , vol.52 , Issue.SUPPL. 3
    • Plotkin, S.A.1
  • 11
    • 79952569307 scopus 로고    scopus 로고
    • Vaccines against Lyme disease: What happened and what lessons can we learn?
    • Poland GA (2011) Vaccines against Lyme disease: What happened and what lessons can we learn? Clin Infect Dis 52 Suppl 3: s253-s258.
    • (2011) Clin Infect Dis , vol.52 , Issue.SUPPL. 3
    • Poland, G.A.1
  • 12
    • 0030756761 scopus 로고    scopus 로고
    • Immunization with a polyvalent OspA vaccine protects mice against Ixodes ricinus tick bites infected by Borrelia burgdorferi ss, Borrelia garinii and Borrelia afzelii
    • DOI 10.1016/S0264-410X(97)00066-2, PII S0264410X97000662
    • Gern L, Hu CM, Voet P, Hauser P, Lobet Y (1997) Immunization with a polyvalent OspA vaccine protects mice against Ixodes ricinus tick bites infected by Borrelia burgdorferi ss, Borrelia garinii and Borrelia afzelii. Vaccine 15: 1551-1557. (Pubitemid 27402138)
    • (1997) Vaccine , vol.15 , Issue.14 , pp. 1551-1557
    • Gern, L.1    Hu, C.M.2    Voet, P.3    Hauser, P.4    Lobet, Y.5
  • 13
    • 0028903299 scopus 로고
    • The Lyme disease vaccine candidate outer surface protein A (OspA) in a formulation compatible with human use protects mice against natural tick transmission of B. Burgdorferi
    • Golde WT, Burkot TR, Piesman J, Dolan MC, Capiau C, et al. (1995) The Lyme disease vaccine candidate outer surface protein A (OspA) in a formulation compatible with human use protects mice against natural tick transmission of B. burgdorferi. Vaccine 13: 435-441.
    • (1995) Vaccine , vol.13 , pp. 435-441
    • Golde, W.T.1    Burkot, T.R.2    Piesman, J.3    Dolan, M.C.4    Capiau, C.5
  • 14
    • 0029053627 scopus 로고
    • Abilities of OspA proteins from different seroprotective groups of Borrelia burgdorferi to protect hamsters from infection
    • Lovrich SD, Callister SM, DuChateau BK, Lim LC, Winfrey J, et al. (1995) Abilities of OspA proteins from different seroprotective groups of Borrelia burgdorferi to protect hamsters from infection. Infect Immun 63: 2113-2119.
    • (1995) Infect Immun , vol.63 , pp. 2113-2119
    • Lovrich, S.D.1    Callister, S.M.2    DuChateau, B.K.3    Lim, L.C.4    Winfrey, J.5
  • 15
    • 84880700297 scopus 로고    scopus 로고
    • Safety and immunogenicity of a novel multivalent OspA vaccine against Lyme borreliosis in healthy adults: A double-blind, randomised, dose-escalation phase I/II clinical trial
    • Wressnigg N, Pollabauer EM, Aichinger G, Portsmouth D, Löw-Baselli A, et al. (2013) Safety and immunogenicity of a novel multivalent OspA vaccine against Lyme borreliosis in healthy adults: a double-blind, randomised, dose-escalation phase I/II clinical trial. Lancet Infect Dis .
    • (2013) Lancet Infect Dis
    • Wressnigg, N.1    Pollabauer, E.M.2    Aichinger, G.3    Portsmouth, D.4    Löw-Baselli, A.5
  • 16
    • 84894132355 scopus 로고    scopus 로고
    • website Available: Accessed 2013 Sep 30
    • Clinical trials.gov website. Phase 1/2 Lyme Vaccine Study. Available: http://clinicaltrials.gov/ct2/show/NCT01504347 . Accessed 2013 Sep 30.
    • Phase 1/2 Lyme Vaccine Study
  • 18
    • 0028593448 scopus 로고
    • The outer surface protein A of the spirochete Borrelia burgdorferi is a plasmin(ogen) receptor
    • Fuchs H, Wallich R, Simon MM, Kramer MD (1994) The outer surface protein A of the spirochete Borrelia burgdorferi is a plasmin(ogen) receptor. Proc Natl Acad Sci U S A 91: 12594-12598.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 12594-12598
    • Fuchs, H.1    Wallich, R.2    Simon, M.M.3    Kramer, M.D.4
  • 19
    • 0031587871 scopus 로고    scopus 로고
    • Plasminogen is required for efficient dissemination of B. burgdorferi in ticks and for enhancement of spirochetemia in mice
    • Coleman JL, Gebbia JA, Piesman J, Degen JL, Bugge TH, et al. (1997) Plasminogen is required for efficient dissemination of B. burgdorferi in ticks and for enhancement of spirochetemia in mice. Cell 89: 1111-1119. (Pubitemid 127678744)
    • (1997) Cell , vol.89 , Issue.7 , pp. 1111-1119
    • Coleman, J.L.1    Gebbia, J.A.2    Piesman, J.3    Degen, J.L.4    Bugge, T.H.5    Benach, J.L.6
  • 21
    • 34547965447 scopus 로고    scopus 로고
    • Tick-host-pathogen interactions in Lyme borreliosis
    • DOI 10.1016/j.pt.2007.07.001, PII S1471492207001699
    • Hovius JW, van Dam AP, Fikrig E (2007) Tick-host-pathogen interactions in Lyme borreliosis. Trends Parasitol 23: 434-438. (Pubitemid 47271975)
    • (2007) Trends in Parasitology , vol.23 , Issue.9 , pp. 434-438
    • Hovius, J.W.R.1    Van Dam, A.P.2    Fikrig, E.3
  • 22
    • 55849126646 scopus 로고    scopus 로고
    • Outer surface protein A protects Lyme disease spirochetes from acquired host immunity in the tick vector
    • Battisti JM, Bono JL, Rosa PA, Schrumpf ME, Schwan TG, et al. (2008) Outer surface protein A protects Lyme disease spirochetes from acquired host immunity in the tick vector. Infect Immun 76: 5228-5237.
    • (2008) Infect Immun , vol.76 , pp. 5228-5237
    • Battisti, J.M.1    Bono, J.L.2    Rosa, P.A.3    Schrumpf, M.E.4    Schwan, T.G.5
  • 23
    • 0033498171 scopus 로고    scopus 로고
    • Immunogenicity of a recombinant Borrelia burgdorferi outer surface protein A vaccine against Lyme disease in children
    • Feder HM Jr, Beran J, Van Hoecke C, Abraham B, De Clercq N, et al. (1999) Immunogenicity of a recombinant Borrelia burgdorferi outer surface protein A vaccine against Lyme disease in children. J Pediatr 135: 575-579.
    • (1999) J Pediatr , vol.135 , pp. 575-579
    • Feder Jr., H.M.1    Beran, J.2    Van Hoecke, C.3    Abraham, B.4    De Clercq, N.5
  • 24
    • 0034002761 scopus 로고    scopus 로고
    • Safety and immunogenicity profile of a recombinant outer-surface protein a Lyme disease vaccine: Clinical trial of a 3-dose schedule at 0, 1, and 2 months
    • DOI 10.1016/S0149-2918(00)80035-1
    • Schoen RT, Sikand VK, Caldwell MC, Van Hoecke C, Gillet M, et al. (2000) Safety and immunogenicity profile of a recombinant outer-surface protein A Lyme disease vaccine: clinical trial of a 3-dose schedule at 0, 1, and 2 months. Clin Ther 22: 315-325. (Pubitemid 30213137)
    • (2000) Clinical Therapeutics , vol.22 , Issue.3 , pp. 315-325
    • Schoen, R.T.1    Sikand, V.K.2    Caldwell, M.C.3    Van Hoecke, C.4    Gillet, M.5    Buscarino, C.6    Parenti, D.L.7
  • 25
    • 0037274138 scopus 로고    scopus 로고
    • An open-label, nonrandomized, single-center, prospective extension, clinical trial of booster dose schedules to assess the safety profile and immunogenicity of recombinant outer-surface protein A (OspA) Lyme disease vaccine
    • DOI 10.1016/S0149-2918(03)90027-0
    • Schoen RT, Deshefy-Longhi T, Van Hoecke C, Buscarino C, Fikrig E (2003) An open-label, nonrandomized, single-center, prospective extension, clinical trial of booster dose schedules to assess the safety profile and immunogenicity of recombinant outer-surface protein A (OspA) Lyme disease vaccine. Clin Ther 25: 210-224. (Pubitemid 36206747)
    • (2003) Clinical Therapeutics , vol.25 , Issue.1 , pp. 210-224
    • Schoen, R.T.1    Deshefy-Longhi, T.2    Van-Hoecke, C.3    Buscarino, C.4    Fikrig, E.5
  • 26
    • 0034956661 scopus 로고    scopus 로고
    • Safety and immunogenicity of a recombinant Borrelia burgdorferi outer surface protein a vaccine against Lyme disease in healthy children and adolescents: A randomized controlled trial
    • DOI 10.1542/peds.108.1.123
    • Sikand VK, Halsey N, Krause PJ, Sood SK, Geller R, et al. (2001) Safety and immunogenicity of a recombinant Borrelia burgdorferi outer surface protein A vaccine against lyme disease in healthy children and adolescents: a randomized controlled trial. Pediatrics 108: 123-128. (Pubitemid 32592015)
    • (2001) Pediatrics , vol.108 , Issue.1 , pp. 123-128
    • Sikand, V.K.1    Halsey, N.2    Krause, P.J.3    Sood, S.K.4    Geller, R.5    Van Hoecke, C.6    Buscarino, C.7    Parenti, D.8
  • 27
    • 77954357410 scopus 로고    scopus 로고
    • Correlates of protection induced by vaccination
    • Plotkin SA (2010) Correlates of protection induced by vaccination. Clin Vaccine Immunol 17: 1055-1065.
    • (2010) Clin Vaccine Immunol , vol.17 , pp. 1055-1065
    • Plotkin, S.A.1
  • 28
    • 0034042121 scopus 로고    scopus 로고
    • Growth-inhibiting antibody responses of humans vaccinated with recombinant outer surface protein a or infected with Borrelia burgdorferi or both
    • DOI 10.1086/315359
    • Luke CJ, Marshall MA, Zahradnik JM, Bybel M, Menefee BE, et al. (2000) Growth-inhibiting antibody responses of humans vaccinated with recombinant outer surface protein A or infected with Borrelia burgdorferi or both. J Infect Dis 181: 1062-1068. (Pubitemid 30194493)
    • (2000) Journal of Infectious Diseases , vol.181 , Issue.3 , pp. 1062-1068
    • Luke, C.J.1    Marshall, M.A.2    Zahradnik, J.M.3    Bybel, M.4    Menefee, B.E.5    Barbour, A.G.6
  • 29
    • 0028331281 scopus 로고
    • Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, or OspC, but not with OspD or the 83-kilodalton antigen
    • Probert WS, LeFebvre RB (1994) Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, or OspC, but not with OspD or the 83-kilodalton antigen. Infect Immun 62: 1920-1926. (Pubitemid 24136997)
    • (1994) Infection and Immunity , vol.62 , Issue.5 , pp. 1920-1926
    • Probert, W.S.1    LeFebvre, R.B.2
  • 30
    • 0028131929 scopus 로고
    • Borrelia burgdorferi antigens that are targeted by antibody-dependent, complement-mediated killing in the rhesus monkey
    • Aydintug MK, Gu Y, Philipp MT (1994) Borrelia burgdorferi antigens that are targeted by antibody-dependent, complement-mediated killing in the rhesus monkey. Infect Immun 62: 4929-4937. (Pubitemid 24332798)
    • (1994) Infection and Immunity , vol.62 , Issue.11 , pp. 4929-4937
    • Aydintug, M.K.1    Gu, Y.2    Philipp, M.T.3
  • 32
    • 0029160257 scopus 로고
    • Incomplete protection of hamsters vaccinated with unlipidated OspA from Borrelia burgdorferi infection is associated with low levels of antibody to an epitope defined by mAb LA-2
    • Johnson BJ, Sviat SL, Happ CM, Dunn JJ, Frantz JC, et al. (1995) Incomplete protection of hamsters vaccinated with unlipidated OspA from Borrelia burgdorferi infection is associated with low levels of antibody to an epitope defined by mAb LA-2. Vaccine 13: 1086-1094.
    • (1995) Vaccine , vol.13 , pp. 1086-1094
    • Johnson, B.J.1    Sviat, S.L.2    Happ, C.M.3    Dunn, J.J.4    Frantz, J.C.5
  • 33
    • 0030765380 scopus 로고    scopus 로고
    • Vaccination of natural reservoir hosts with recombinant lipidated OspA induces a transmission-blocking immunity against Lyme disease spirochaetes associated with high levels of LA-2 equivalent antibodies
    • DOI 10.1016/S0264-410X(97)00086-8, PII S0264410X97000868
    • Kurtenbach K, Dizij A, Voet P, Hauser P, Simon MM (1997) Vaccination of natural reservoir hosts with recombinant lipidated OspA induces a transmission-blocking immunity against Lyme disease spirochaetes associated with high levels of LA-2 equivalent antibodies. Vaccine 15: 1670-1674. (Pubitemid 27445746)
    • (1997) Vaccine , vol.15 , Issue.15 , pp. 1670-1674
    • Kurtenbach, K.1    Dizij, A.2    Voet, P.3    Hauser, P.4    Simon, M.M.5
  • 34
    • 0029917096 scopus 로고    scopus 로고
    • Detection of anti-Borrelia burgdorferi antibody responses with the borreliacidal antibody test, indirect fluorescent-antibody assay performed by flow cytometry, and western immunoblotting
    • Creson JR, Lim LC, Glowacki NJ, Callister SM, Schell RF (1996) Detection of anti-Borrelia burgdorferi antibody responses with the borreliacidal antibody test, indirect fluorescent-antibody assay performed by flow cytometry, and western immunoblotting. Clin Diagn Lab Immunol 3: 184-190. (Pubitemid 26103754)
    • (1996) Clinical and Diagnostic Laboratory Immunology , vol.3 , Issue.2 , pp. 184-190
    • Creson, J.R.1    Lim, L.C.L.2    Glowacki, N.J.3    Callister, S.M.4    Schell, R.F.5
  • 36
    • 84877831723 scopus 로고    scopus 로고
    • Quantitative Detection of Borrelia burgdorferi sensu lato in Erythema Migrans Skin Lesions Using Internally Controlled Duplex Real Time PCR
    • O'Rourke M, Traweger A, Lusa L, Stupica D, Maraspin V, et al. (2013) Quantitative Detection of Borrelia burgdorferi sensu lato in Erythema Migrans Skin Lesions Using Internally Controlled Duplex Real Time PCR. PLoS One 8: e63968.
    • (2013) PLoS One , vol.8
    • O'Rourke, M.1    Traweger, A.2    Lusa, L.3    Stupica, D.4    Maraspin, V.5
  • 38
    • 0029010350 scopus 로고
    • Growth inhibition of Borrelia burgdorferi sensu lato by antibodies. A contribution to understanding the pathogenesis and improving diagnosis of Lyme borreliosis
    • Sadziene A, Barbour AG (1995) [Growth inhibition of Borrelia burgdorferi sensu lato by antibodies. A contribution to understanding the pathogenesis and improving diagnosis of Lyme borreliosis]. Wien Med Wochenschr 145: 162-165.
    • (1995) Wien Med Wochenschr , vol.145 , pp. 162-165
    • Sadziene, A.1    Barbour, A.G.2
  • 39
    • 0037900067 scopus 로고    scopus 로고
    • Investigations on the mode and dynamics of transmission and infectivity of Borrelia burgdorferi sensu stricto and Borrelia afzelii in Ixodes ricinus ticks
    • Crippa M, Rais O, Gern L (2002) Investigations on the mode and dynamics of transmission and infectivity of Borrelia burgdorferi sensu stricto and Borrelia afzelii in Ixodes ricinus ticks. Vector Borne Zoonotic Dis 2: 3-9.
    • (2002) Vector Borne Zoonotic Dis , vol.2 , pp. 3-9
    • Crippa, M.1    Rais, O.2    Gern, L.3
  • 40
    • 0000475694 scopus 로고
    • Histological examination of Borrelia burgdorferi infections in unfed Ixodes ricinus nymphs
    • Lebet N, Gern L (1994) Histological examination of Borrelia burgdorferi infections in unfed Ixodes ricinus nymphs. Experimental & Applied Acarology 18: 177-183.
    • (1994) Experimental & Applied Acarology , vol.18 , pp. 177-183
    • Lebet, N.1    Gern, L.2
  • 41
    • 0028387455 scopus 로고
    • Characterization of Borrelia burgdorferi isolated from different organs of Ixodes ricinus ticks collected in nature
    • Leuba-Garcia S, Kramer MD, Wallich R, Gern L (1994) Characterization of Borrelia burgdorferi isolated from different organs of Ixodes ricinus ticks collected in nature. Zentralbl Bakteriol 280: 468-475. (Pubitemid 2068444)
    • (1994) Zentralblatt fur Bakteriologie , vol.280 , Issue.4 , pp. 468-475
    • Leuba-Garcia, S.1    Kramer, M.D.2    Wallich, R.3    Gern, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.