Cancer and inflammation: Differentiation by USPIO-enhanced MR imaging

Journal of Magnetic Resonance Imaging

Volumn 39, Issue 3, 2014, Pages 665-672

  Seyfer, Perla ^a   Pagenstecher, Axel ^a   Mandic, Robert ^a   Klose, Klaus Jochen ^a   Heverhagen, Johannes T ^b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

cancer; contrast media; inflammation; MRI; USPIO

Indexed keywords

DEXTRAN; FERUMOXTRAN-10; MAGNETITE NANOPARTICLE;

ABSCESS; ANIMAL; CANCER TRANSPLANTATION; COMPARATIVE STUDY; DIAGNOSTIC USE; DIFFERENTIAL DIAGNOSIS; DISEASE MODEL; HUMAN; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; NEEDLE BIOPSY; NEOPLASMS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PROCEDURES; RABBIT; RANDOMIZATION; XENOGRAFT;

ABSCESS; ANIMALS; BIOPSY, NEEDLE; DEXTRANS; DIAGNOSIS, DIFFERENTIAL; DISEASE MODELS, ANIMAL; HETEROGRAFTS; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MALE; NEOPLASM TRANSPLANTATION; NEOPLASMS; RABBITS; RANDOM ALLOCATION;

EID: 84894048921     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.24200     Document Type: Article

References (30)

1. Anzai Y, Prince MR,. Iron oxide-enhanced MR lymphography: the evaluation of cervical lymph node metastases in head and neck cancer. J Magn Reson Imaging 1997; 7: 75-81.
2. Bellin MF, Roy C, Kinkel K, et al. Lymph node metastases: safety and effectiveness of MR imaging with ultrasmall superparamagnetic iron oxide particles-initial clinical experience. Radiology 1998; 207: 799-808.
3. Koh DM, Brown G, Temple L, et al. Rectal cancer: mesorectal lymph nodes at MR imaging with USPIO versus histopathologic finding-initial observations. Radiology 2004; 231: 91-99.
4. Mack MG, Balzer JO, Straub R, Eichler K, Vogl TJ,. Superparamagnetic iron oxide-enhanced MR imaging of head and neck lymph nodes. Radiology 2002; 222: 239-244.
5. Weissleder R, Elizondo G, Wittenberg J, Lee AS, Josephson L, Brady TJ,. Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging. Radiology 1990; 175: 494-498.
6. Hauger O, Delalande C, Deminiere C, et al. Nephrotoxic nephritis and obstructive nephropathy: evaluation with MR imaging enhanced with ultrasmall superparamagnetic iron oxide-preliminary findings in a rat model. Radiology 2000; 217: 819-826.
7. Deserno WM, Harisinghani MG, Taupitz M, et al. Urinary bladder cancer: preoperative nodal staging with ferumoxtran- 10-enhanced MR imaging. Radiology 2004; 233: 449-456.
8. Memarsadeghi M, Riedl CC, Kaneider A, et al. Axillary lymph node metastases in patients with breast carcinomas: assessment with nonenhanced versus USPIO-enhanced MR imaging. Radiology 2006; 241: 367-377.
9. Harisinghani MG, Saksena MA, Hahn PF, et al. Ferumoxtran-10-enhanced MR lymphangiography: does contrast-enhanced imaging alone suffice for accurate lymph node characterization? AJR Am J Roentgenol 2006; 186: 144-148.
10. Nishimura H, Tanigawa N, Hiramatsu M, Tatsumi Y, Matsuki M, Narabayashi I,. Preoperative esophageal cancer staging: magnetic resonance imaging of lymph node with ferumoxtran-10, an ultrasmall superparamagnetic iron oxide. J Am Coll Surg 2006; 202: 604-611.
11. Stets C, Brandt S, Wallis F, Buchmann J, Gilbert FJ, Heywang-Kobrunner SH,. Axillary lymph node metastases: a statistical analysis of various parameters in MRI with USPIO. J Magn Reson Imaging 2002; 16: 60-68.
12. Taupitz M, Wagner S, Hamm B, Binder A, Pfefferer D,. Interstitial MR lymphography with iron oxide particles: results in tumor-free and VX2 tumor-bearing rabbits. AJR Am J Roentgenol 1993; 161: 193-200.
13. Lutz AM, Seemayer C, Corot C, et al. Detection of synovial macrophages in an experimental rabbit model of antigen-induced arthritis: ultrasmall superparamagnetic iron oxide-enhanced MR imaging. Radiology 2004; 233: 149-157.
14. Arbab AS, Ichikawa T, Sou H, et al. Ferumoxides-enhanced double-echo T2-weighted MR imaging in differentiating metastases from nonsolid benign lesions of the liver. Radiology 2002; 225: 151-158.
15. Daldrup-Link HE, Rummeny EJ, Ihssen B, Kienast J, Link TM,. Iron-oxide enhanced MR imaging of bone marrow in patients with non-Hodgkin's lymphoma: differentiation between tumor infiltration and hypercellular bone marrow. Eur Radiol 2002; 12: 1557-1566.
16. Kanno S, Wu YJ, Lee PC,. Macrophage accumulation associated with rat cardiac allograft rejection detected by magnetic resonance imaging with ultrasmall superparamagnetic iron oxide particles. Circulation 2001; 104: 934-938.
17. Lutz AM, Gopfert K, Jochum W, Nanz D, Frohlich JM, Weishaupt D,. USPIO-enhanced MR imaging for visualization of synovial hyperperfusion and detection of synovial macrophages: preliminary results in an experimental model of antigen induced arthritis. J Magn Reson Imaging 2006; 24: 657-666.
18. Metz S, Bonaterra G, Rudelius M, Settles M, Rummeny EJ, Daldrup-Link HE,. Capacity of human monocytes to phagocytose approved iron oxide MR contrast agents in vitro. Eur Radiol 2004; 14: 1851-1858.
19. Heverhagen JT,. Noise measurement and estimation in MR imaging experiments. Radiology 2007; 245: 638-639.
20. Rausch M, Baumann D, Neubacher U, Rudin M,. In-vivo visualization of phagocytotic cells in rat brains after transient ischemia by USPIO. NMR Biomed 2002; 15: 278-283.
21. Weissleder R, Cheng HC, Bogdanova A, Bogdanov A,. Magnetically labeled cells can be detected by MR imaging. J Magn Reson Imaging 1997; 7: 258-263.
22. Dousset V, Ballarino L, Delalande C, et al. Comparison of ultrasmall particles of iron oxide (USPIO)-enhanced T2-weighted, conventional T2-weighted, and gadolinium- enhanced T1- weighted MR images in rats with experimental autoimmune encephalomyelitis. AJNR Am J Neuroradiol 1999; 20: 223-227.
23. Tatsumi Y, Tanigawa N, Nishimura H, et al. Preoperative diagnosis of lymph node metastases in gastric cancer by magnetic resonance imaging with ferumoxtran-10. Gastric Cancer 2006; 9: 120-128.
24. Chan TW, Eley C, Liberti P, So A, Kressel HY,. Magnetic resonance imaging of abscesses using lipid-coated iron oxide particles. Invest Radiol 1992; 27: 443-449.
25. Gellissen J, Axmann C, Prescher A, Bohndorf K, Lodemann KP,. Extra- and intracellular accumulation of ultrasmall superparamagnetic iron oxides (USPIO) in experimentally induced abscesses of the peripheral soft tissues and their effects on magnetic resonance imaging. Magn Reson Imaging 1999; 17: 557-567.
26. Kaim AH, Wischer T, O'Reilly T, et al. MR imaging with ultrasmall superparamagnetic iron oxide particles in experimental soft-tissue infections in rats. Radiology 2002; 225: 808-814.
27. Thorek DL, Weisshaar CL, Czupryna JC, Winkelstein BA, Tsourkas A,. Superparamagnetic iron oxide-enhanced magnetic resonance imaging of neuroinflammation in a rat model of radicular pain. Mol Imaging 2011; 10: 206-214.
28. Lutz AM, Weishaupt D, Persohn E, et al. Imaging of macrophages in soft-tissue infection in rats: relationship between ultrasmall superparamagnetic iron oxide dose and MR signal characteristics. Radiology 2005; 234: 765-775.
29. Triantafyllou M, Studer UE, Birkhauser FD, et al. Ultrasmall superparamagnetic particles of iron oxide allow for the detection of metastases in normal sized pelvic lymph nodes of patients with bladder and/or prostate cancer. Eur J Cancer 2013; 49: 616-624.
30. Kinner S, Maderwald S, Albert J, et al. Comparison of two different iron oxide-based contrast agents for discrimination of benign and malignant lymph nodes. Invest Radiol 2012; 47: 511-515.